Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Phf20l1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PHF20L1 mRNA | CTD | PMID:36331819 | Phf20l1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of PHF20L1 mRNA | CTD | PMID:28960355 | Phf20l1 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Phf20l1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of PHF20L1 mRNA | CTD | PMID:22206623 | Phf20l1 | Rat | 17beta-estradiol | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of PHF20L1 mRNA | CTD | PMID:19167446 | Phf20l1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Phf20l1 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Phf20l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHF20L1 mRNA | CTD | PMID:22298810 | Phf20l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PHF20L1 mRNA | CTD | PMID:32109520 and PMID:33387578 | Phf20l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHF20L1 mRNA | CTD | PMID:22574217 | Phf20l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHF20L1 mRNA | CTD | PMID:21570461 | Phf20l1 | Rat | 2-methylcholine | affects expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of PHF20L1 mRNA | CTD | PMID:21179406 | Phf20l1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PHF20L1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PHF20L1 mRNA | CTD | PMID:28628672 | Phf20l1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PHF20L1 mRNA | CTD | PMID:28628672 | Phf20l1 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of PHF20L1 mRNA | CTD | PMID:28973697 | Phf20l1 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PHF20L1 mRNA | CTD | PMID:28973697 | Phf20l1 | Rat | aflatoxin B1 | increases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PHF20L1 mRNA | CTD | PMID:19770486 | Phf20l1 | Rat | aflatoxin B1 | decreases methylation | ISO | PHF20L1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PHF20L1 gene | CTD | PMID:27153756 | Phf20l1 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | PHF20L1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of PHF20L1 intron | CTD | PMID:30157460 | Phf20l1 | Rat | amiodarone | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of PHF20L1 mRNA | CTD | PMID:19774075 | Phf20l1 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PHF20L1 mRNA | CTD | PMID:38685447 | Phf20l1 | Rat | antirheumatic drug | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PHF20L1 mRNA | CTD | PMID:24449571 | Phf20l1 | Rat | aristolochic acid A | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PHF20L1 mRNA | CTD | PMID:33212167 | Phf20l1 | Rat | Aroclor 1254 | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of PHF20L1 mRNA | CTD | PMID:23650126 | Phf20l1 | Rat | arsane | affects methylation | ISO | PHF20L1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PHF20L1 gene | CTD | PMID:25304211 | Phf20l1 | Rat | arsenic atom | affects methylation | ISO | PHF20L1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PHF20L1 gene | CTD | PMID:25304211 | Phf20l1 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of PHF20L1 gene | CTD | PMID:35440735 | Phf20l1 | Rat | benzo[a]pyrene | increases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PHF20L1 mRNA | CTD | PMID:22228805 | Phf20l1 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of PHF20L1 mRNA | CTD | PMID:31163220 | Phf20l1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PHF20L1 mRNA | CTD | PMID:25181051 more ... | Phf20l1 | Rat | bisphenol A | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PHF20L1 mRNA | CTD | PMID:36232920 | Phf20l1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PHF20L1 mRNA | CTD | PMID:32528016 | Phf20l1 | Rat | bisphenol A | decreases methylation | ISO | PHF20L1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of PHF20L1 gene | CTD | PMID:31601247 | Phf20l1 | Rat | bisphenol A | affects splicing | ISO | Phf20l1 (Mus musculus) | 6480464 | bisphenol A affects the splicing of PHF20L1 mRNA | CTD | PMID:37894381 | Phf20l1 | Rat | bisphenol A | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PHF20L1 mRNA | CTD | PMID:28628672 | Phf20l1 | Rat | butanal | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of PHF20L1 mRNA | CTD | PMID:26079696 | Phf20l1 | Rat | cadmium dichloride | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PHF20L1 mRNA | CTD | PMID:38568856 | Phf20l1 | Rat | CGP 52608 | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PHF20L1 gene] | CTD | PMID:28238834 | Phf20l1 | Rat | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of PHF20L1 mRNA | CTD | PMID:23125180 | Phf20l1 | Rat | chrysene | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | chrysene results in decreased expression of PHF20L1 mRNA | CTD | PMID:26377693 | Phf20l1 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of PHF20L1 mRNA | CTD | PMID:24386269 | Phf20l1 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of PHF20L1 mRNA | CTD | PMID:30556269 | Phf20l1 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of PHF20L1 mRNA | CTD | PMID:30556269 | Phf20l1 | Rat | coumestrol | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PHF20L1 mRNA | CTD | PMID:19167446 | Phf20l1 | Rat | coumestrol | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of PHF20L1 mRNA | CTD | PMID:19167446 | Phf20l1 | Rat | crocidolite asbestos | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of PHF20L1 mRNA | CTD | PMID:29279043 | Phf20l1 | Rat | dexamethasone | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PHF20L1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PHF20L1 mRNA | CTD | PMID:28628672 | Phf20l1 | Rat | Dibutyl phosphate | affects expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of PHF20L1 mRNA | CTD | PMID:37042841 | Phf20l1 | Rat | dibutyl phthalate | increases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of PHF20L1 mRNA | CTD | PMID:21266533 | Phf20l1 | Rat | dorsomorphin | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Phf20l1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PHF20L1 mRNA | CTD | PMID:29391264 | Phf20l1 | Rat | Enterolactone | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PHF20L1 mRNA | CTD | PMID:19167446 | Phf20l1 | Rat | entinostat | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of PHF20L1 mRNA | CTD | PMID:26272509 and PMID:27188386 | Phf20l1 | Rat | entinostat | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF20L1 mRNA | CTD | PMID:27188386 | Phf20l1 | Rat | ethyl methanesulfonate | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of PHF20L1 mRNA | CTD | PMID:23649840 | Phf20l1 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of PHF20L1 mRNA | CTD | PMID:31881178 | Phf20l1 | Rat | folic acid | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of PHF20L1 mRNA | CTD | PMID:21867686 | Phf20l1 | Rat | folic acid | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PHF20L1 mRNA | CTD | PMID:25629700 | Phf20l1 | Rat | FR900359 | increases phosphorylation | ISO | PHF20L1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of PHF20L1 protein | CTD | PMID:37730182 | Phf20l1 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of PHF20L1 mRNA | CTD | PMID:25539665 | Phf20l1 | Rat | genistein | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Genistein results in decreased expression of PHF20L1 mRNA | CTD | PMID:32186404 | Phf20l1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PHF20L1 mRNA | CTD | PMID:33387578 | Phf20l1 | Rat | glyphosate | decreases methylation | EXP | | 6480464 | Glyphosate results in decreased methylation of PHF20L1 gene | CTD | PMID:31011160 | Phf20l1 | Rat | hydrogen peroxide | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of PHF20L1 mRNA | CTD | PMID:18951874 | Phf20l1 | Rat | indometacin | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PHF20L1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PHF20L1 mRNA | CTD | PMID:28628672 | Phf20l1 | Rat | methyl methanesulfonate | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PHF20L1 mRNA | CTD | PMID:23649840 | Phf20l1 | Rat | methylmercury chloride | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PHF20L1 mRNA | CTD | PMID:28001369 | Phf20l1 | Rat | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of PHF20L1 mRNA | CTD | PMID:24136188 | Phf20l1 | Rat | ozone | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of PHF20L1 mRNA | CTD | PMID:35430440 | Phf20l1 | Rat | p-chloromercuribenzoic acid | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of PHF20L1 mRNA | CTD | PMID:26272509 | Phf20l1 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF20L1 mRNA | CTD | PMID:27188386 | Phf20l1 | Rat | paracetamol | affects expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PHF20L1 mRNA | CTD | PMID:17562736 | Phf20l1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PHF20L1 mRNA | CTD | PMID:33387578 | Phf20l1 | Rat | PCB138 | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Phf20l1 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PHF20L1 mRNA | CTD | PMID:27153767 | Phf20l1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PHF20L1 mRNA | CTD | PMID:36331819 | Phf20l1 | Rat | phenobarbital | affects expression | ISO | Phf20l1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of PHF20L1 mRNA | CTD | PMID:23091169 | Phf20l1 | Rat | pirinixic acid | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PHF20L1 mRNA | CTD | PMID:19710929 | Phf20l1 | Rat | resveratrol | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PHF20L1 mRNA | CTD | PMID:23557933 | Phf20l1 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of PHF20L1 mRNA | CTD | PMID:19013527 | Phf20l1 | Rat | SB 431542 | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Phf20l1 | Rat | silicon dioxide | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PHF20L1 mRNA | CTD | PMID:25895662 | Phf20l1 | Rat | sodium arsenite | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PHF20L1 mRNA | CTD | PMID:38568856 | Phf20l1 | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of PHF20L1 mRNA | CTD | PMID:22110744 | Phf20l1 | Rat | succimer | multiple interactions | ISO | Phf20l1 (Mus musculus) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of PHF20L1 mRNA | CTD | PMID:26378955 | Phf20l1 | Rat | tetraphene | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of PHF20L1 mRNA | CTD | PMID:26377693 | Phf20l1 | Rat | thimerosal | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of PHF20L1 mRNA | CTD | PMID:16870260 | Phf20l1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PHF20L1 mRNA | CTD | PMID:23411599 | Phf20l1 | Rat | thiram | increases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Thiram results in increased expression of PHF20L1 mRNA | CTD | PMID:38568856 | Phf20l1 | Rat | titanium dioxide | increases methylation | ISO | Phf20l1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of PHF20L1 gene | CTD | PMID:35295148 | Phf20l1 | Rat | toluene | increases expression | EXP | | 6480464 | Toluene results in increased expression of PHF20L1 mRNA | CTD | PMID:22967744 | Phf20l1 | Rat | trichostatin A | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of PHF20L1 mRNA | CTD | PMID:24935251 and PMID:26272509 | Phf20l1 | Rat | trichostatin A | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF20L1 mRNA | CTD | PMID:27188386 | Phf20l1 | Rat | troglitazone | decreases expression | ISO | Phf20l1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of PHF20L1 mRNA | CTD | PMID:28973697 | Phf20l1 | Rat | valproic acid | decreases expression | ISO | PHF20L1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PHF20L1 mRNA | CTD | PMID:23179753 more ... | Phf20l1 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of PHF20L1 mRNA | CTD | PMID:29427782 | Phf20l1 | Rat | valproic acid | multiple interactions | ISO | PHF20L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF20L1 mRNA | CTD | PMID:27188386 | Phf20l1 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of PHF20L1 mRNA | CTD | PMID:19015723 | Phf20l1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of PHF20L1 mRNA | CTD | PMID:23034163 | Phf20l1 | Rat | vinclozolin | decreases methylation | EXP | | 6480464 | vinclozolin results in decreased methylation of PHF20L1 gene | CTD | PMID:31079544 | |
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