Ugt2b10 (UDP glucuronosyltransferase 2 family, polypeptide B10) - Rat Genome Database

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Gene: Ugt2b10 (UDP glucuronosyltransferase 2 family, polypeptide B10) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ugt2b10
Name: UDP glucuronosyltransferase 2 family, polypeptide B10
RGD ID: 1309989
Description: Predicted to enable glucuronosyltransferase activity. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305264; UDP glucuronosyltransferase 2 family, polypeptide B34; UDP glycosyltransferase 2 family, polypeptide B10; UDP-glucuronosyltransferase 2B10; Ugt2b34
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,436,939 - 21,483,494 (+)NCBIGRCr8
mRatBN7.21421,107,996 - 21,128,648 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,108,006 - 21,127,828 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1421,447,268 - 21,476,568 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01422,766,204 - 22,795,506 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01421,297,288 - 21,326,588 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01422,806,132 - 22,826,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01422,700,436 - 22,725,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41422,725,811 - 22,745,391 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11422,726,191 - 22,745,391 (+)NCBI
Celera1420,601,357 - 20,620,726 (+)NCBICelera
Cytogenetic Map14p21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Variants

.
Variants in Ugt2b10
139 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:30
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000002728
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141487516830883947Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000002724   ⟹   ENSRNOP00000002724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1421,024,035 - 21,035,784 (+)Ensembl
Rnor_6.0 Ensembl1422,724,399 - 22,736,148 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000002728   ⟹   ENSRNOP00000002728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1421,108,006 - 21,127,828 (+)Ensembl
Rnor_6.0 Ensembl1422,806,132 - 22,825,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089471   ⟹   ENSRNOP00000069054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)Ensembl
Rnor_6.0 Ensembl1422,724,070 - 22,806,839 (+)Ensembl
RefSeq Acc Id: NM_001191676   ⟹   NP_001178605
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,462,841 - 21,483,494 (+)NCBI
mRatBN7.21421,107,996 - 21,128,648 (+)NCBI
Rnor_6.01422,806,132 - 22,825,444 (+)NCBI
Rnor_5.01422,700,436 - 22,725,838 (+)NCBI
Celera1420,601,357 - 20,620,726 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063273072   ⟹   XP_063129142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,436,939 - 21,483,480 (+)NCBI
RefSeq Acc Id: XM_063273073   ⟹   XP_063129143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,462,803 - 21,483,480 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178605 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129142 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129143 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002728.2
RefSeq Acc Id: NP_001178605   ⟸   NM_001191676
- Peptide Label: precursor
- UniProtKB: D4A132 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002728   ⟸   ENSRNOT00000002728
Ensembl Acc Id: ENSRNOP00000002724   ⟸   ENSRNOT00000002724
Ensembl Acc Id: ENSRNOP00000069054   ⟸   ENSRNOT00000089471
RefSeq Acc Id: XP_063129142   ⟸   XM_063273072
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129143   ⟸   XM_063273073
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699258
Promoter ID:EPDNEW_R9783
Type:multiple initiation site
Name:Ugt2b17_1
Description:UDP glucuronosyltransferase family 2 member B17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9782  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01422,806,105 - 22,806,165EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309989 AgrOrtholog
BioCyc Gene G2FUF-16090 BioCyc
Ensembl Genes ENSRNOG00000001990 Ensembl
  ENSRNOG00000062781 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002728.3 UniProtKB/TrEMBL
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/TrEMBL
InterPro UDP-glycosyltransferase UniProtKB/TrEMBL
  UDP_glucos_trans UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/TrEMBL
KEGG Report rno:305264 UniProtKB/TrEMBL
NCBI Gene 305264 ENTREZGENE
PANTHER EG:EG0003.4 PROTEIN-RELATED UniProtKB/TrEMBL
  UDP-GLUCURONOSYLTRANSFERASE UniProtKB/TrEMBL
Pfam UDPGT UniProtKB/TrEMBL
PharmGKB UGT2B10 RGD
PhenoGen Ugt2b10 PhenoGen
PROSITE UDPGT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001990 RatGTEx
  ENSRNOG00000062781 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/TrEMBL
UniProt D4A132 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-02-02 Ugt2b10  UDP glucuronosyltransferase 2 family, polypeptide B10  Ugt2b34  UDP glucuronosyltransferase 2 family, polypeptide B34  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ugt2b34  UDP glucuronosyltransferase 2 family, polypeptide B34  Ugt2b10_predicted  UDP glycosyltransferase 2 family, polypeptide B10 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Ugt2b10_predicted  UDP glycosyltransferase 2 family, polypeptide B10 (predicted)      Symbol and Name status set to approved 70820 APPROVED