Tmcc3 (transmembrane and coiled-coil domain family 3) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Tmcc3 (transmembrane and coiled-coil domain family 3) Rattus norvegicus
Analyze
Symbol: Tmcc3
Name: transmembrane and coiled-coil domain family 3
RGD ID: 1307241
Description: Predicted to enable 14-3-3 protein binding activity and identical protein binding activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in endomembrane system. Orthologous to human TMCC3 (transmembrane and coiled-coil domain family 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC314751; RGD1307241; similar to RIKEN cDNA C630016B22 gene; transmembrane and coiled coil domains 3; transmembrane and coiled-coil domain protein 3; transmembrane and coiled-coil domains protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,781,452 - 31,058,888 (+)NCBIGRCr8
mRatBN7.2728,893,972 - 29,171,935 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,893,967 - 29,171,926 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx731,098,421 - 31,170,349 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0733,261,070 - 33,333,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0733,031,565 - 33,103,518 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0735,266,953 - 35,543,770 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl735,309,265 - 35,543,759 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0735,333,406 - 35,608,386 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4731,691,945 - 31,764,354 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1731,712,381 - 31,780,818 (+)NCBI
Celera726,189,445 - 26,261,477 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-dichloroaniline  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
crocidolite asbestos  (ISO)
Dibutyl phosphate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
enzalutamide  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
isoprenaline  (ISO)
manganese(II) chloride  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
mocetinostat  (ISO)
morphine  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
ozone  (ISO)
paracetamol  (EXP)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sunitinib  (ISO)
tacedinaline  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:25931508   PMID:27697108  


Genomics

Comparative Map Data
Tmcc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,781,452 - 31,058,888 (+)NCBIGRCr8
mRatBN7.2728,893,972 - 29,171,935 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,893,967 - 29,171,926 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx731,098,421 - 31,170,349 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0733,261,070 - 33,333,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0733,031,565 - 33,103,518 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0735,266,953 - 35,543,770 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl735,309,265 - 35,543,759 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0735,333,406 - 35,608,386 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4731,691,945 - 31,764,354 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1731,712,381 - 31,780,818 (+)NCBI
Celera726,189,445 - 26,261,477 (+)NCBICelera
Cytogenetic Map7q13NCBI
TMCC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381294,567,122 - 94,650,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1294,567,122 - 94,650,557 (-)EnsemblGRCh38hg38GRCh38
GRCh371294,960,898 - 95,044,333 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361293,486,168 - 93,568,455 (-)NCBINCBI36Build 36hg18NCBI36
Build 341293,464,516 - 93,546,792NCBI
Celera1294,632,124 - 94,715,494 (-)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1292,028,002 - 92,111,318 (-)NCBIHuRef
CHM1_11294,925,848 - 95,009,358 (-)NCBICHM1_1
T2T-CHM13v2.01294,547,898 - 94,631,383 (-)NCBIT2T-CHM13v2.0
Tmcc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391094,147,544 - 94,426,816 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1094,147,811 - 94,426,818 (+)EnsemblGRCm39 Ensembl
GRCm381094,311,682 - 94,590,954 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1094,311,949 - 94,590,956 (+)EnsemblGRCm38mm10GRCm38
MGSCv371093,977,602 - 94,053,699 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361093,944,678 - 94,020,753 (+)NCBIMGSCv36mm8
Celera1096,487,680 - 96,563,644 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.88NCBI
Tmcc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540531,262,019 - 31,268,612 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540531,258,087 - 31,484,029 (-)NCBIChiLan1.0ChiLan1.0
TMCC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210102,631,360 - 102,940,098 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112102,627,724 - 102,936,490 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01292,150,075 - 92,233,394 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11295,508,740 - 95,556,182 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1295,508,740 - 95,556,182 (-)Ensemblpanpan1.1panPan2
TMCC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11534,624,804 - 34,850,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1534,629,079 - 34,638,550 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1535,010,916 - 35,272,624 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01535,288,245 - 35,549,907 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1535,290,221 - 35,359,506 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11534,561,751 - 34,823,350 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01534,651,390 - 34,913,699 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01534,920,090 - 35,182,019 (-)NCBIUU_Cfam_GSD_1.0
Tmcc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494525,137,690 - 25,349,231 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650710,886,202 - 11,095,457 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650710,886,187 - 10,905,945 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMCC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl588,438,365 - 88,682,319 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1588,409,560 - 88,682,328 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,038,097 - 93,105,107 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMCC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11189,964,934 - 90,216,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1189,969,260 - 89,979,591 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037154,895,315 - 155,203,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmcc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475012,338,033 - 12,400,385 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475012,186,314 - 12,404,661 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmcc3
2403 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:490
Count of miRNA genes:252
Interacting mature miRNAs:334
Transcripts:ENSRNOT00000010316
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat

Markers in Region
RH143281  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2729,171,571 - 29,171,780 (+)MAPPERmRatBN7.2
Rnor_6.0735,543,405 - 35,543,613NCBIRnor6.0
Rnor_5.0735,608,023 - 35,608,231UniSTSRnor5.0
RGSC_v3.4731,764,000 - 31,764,208UniSTSRGSC3.4
Celera726,261,123 - 26,261,331UniSTS
RH 3.4 Map7207.2UniSTS
Cytogenetic Map7q13UniSTS
RH131191  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2729,171,685 - 29,171,867 (+)MAPPERmRatBN7.2
Rnor_6.0735,543,519 - 35,543,700NCBIRnor6.0
Rnor_5.0735,608,137 - 35,608,318UniSTSRnor5.0
RGSC_v3.4731,764,114 - 31,764,295UniSTSRGSC3.4
Celera726,261,237 - 26,261,418UniSTS
Cytogenetic Map7q13UniSTS
RH137473  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2729,152,390 - 29,152,573 (+)MAPPERmRatBN7.2
Rnor_6.0735,524,169 - 35,524,351NCBIRnor6.0
Rnor_5.0735,588,763 - 35,588,945UniSTSRnor5.0
RGSC_v3.4731,744,223 - 31,744,405UniSTSRGSC3.4
Celera726,241,930 - 26,242,112UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000010316   ⟹   ENSRNOP00000010316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl729,100,175 - 29,171,926 (+)Ensembl
Rnor_6.0 Ensembl735,472,102 - 35,543,759 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080291   ⟹   ENSRNOP00000074786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl729,158,911 - 29,171,926 (+)Ensembl
Rnor_6.0 Ensembl735,309,265 - 35,541,344 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094886   ⟹   ENSRNOP00000076849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl728,893,967 - 29,171,926 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095728   ⟹   ENSRNOP00000079968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl728,978,702 - 29,171,926 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101181   ⟹   ENSRNOP00000077448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl729,134,170 - 29,171,926 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102476   ⟹   ENSRNOP00000081540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl729,135,020 - 29,171,926 (+)Ensembl
RefSeq Acc Id: NM_001108084   ⟹   NP_001101554
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,987,133 - 31,058,879 (+)NCBI
mRatBN7.2729,100,175 - 29,171,926 (+)NCBI
Rnor_6.0735,472,102 - 35,543,759 (+)NCBI
Rnor_5.0735,333,406 - 35,608,386 (+)NCBI
RGSC_v3.4731,691,945 - 31,764,354 (+)RGD
Celera726,189,445 - 26,261,477 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241261   ⟹   XP_006241323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8731,022,010 - 31,058,888 (+)NCBI
mRatBN7.2729,135,003 - 29,171,935 (+)NCBI
Rnor_6.0735,506,904 - 35,543,770 (+)NCBI
Rnor_5.0735,333,406 - 35,608,386 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594836   ⟹   XP_017450325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,693 - 31,058,888 (+)NCBI
mRatBN7.2728,893,972 - 29,171,935 (+)NCBI
Rnor_6.0735,309,222 - 35,543,770 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594840   ⟹   XP_017450329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,904 - 31,058,888 (+)NCBI
mRatBN7.2728,935,931 - 29,171,935 (+)NCBI
Rnor_6.0735,309,222 - 35,543,770 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079073   ⟹   XP_038935001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,904 - 31,058,888 (+)NCBI
mRatBN7.2728,893,972 - 29,171,935 (+)NCBI
RefSeq Acc Id: XM_039079074   ⟹   XP_038935002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,680 - 31,058,888 (+)NCBI
mRatBN7.2728,894,707 - 29,171,935 (+)NCBI
RefSeq Acc Id: XM_039079076   ⟹   XP_038935004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,839,443 - 31,058,888 (+)NCBI
mRatBN7.2728,974,874 - 29,171,935 (+)NCBI
RefSeq Acc Id: XM_039079077   ⟹   XP_038935005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,675 - 31,058,888 (+)NCBI
mRatBN7.2728,894,729 - 29,171,935 (+)NCBI
RefSeq Acc Id: XM_039079079   ⟹   XP_038935007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,897,988 - 31,058,888 (+)NCBI
mRatBN7.2729,011,039 - 29,171,935 (+)NCBI
RefSeq Acc Id: XM_039079081   ⟹   XP_038935009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,897,988 - 31,058,888 (+)NCBI
mRatBN7.2729,011,024 - 29,171,935 (+)NCBI
RefSeq Acc Id: XM_063263446   ⟹   XP_063119516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8731,021,944 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263447   ⟹   XP_063119517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,904 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263448   ⟹   XP_063119518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,904 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263449   ⟹   XP_063119519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,904 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263450   ⟹   XP_063119520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,693 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263451   ⟹   XP_063119521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,693 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263452   ⟹   XP_063119522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,693 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263453   ⟹   XP_063119523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,682 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263454   ⟹   XP_063119524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8731,020,649 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263455   ⟹   XP_063119525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8731,014,968 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263456   ⟹   XP_063119526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,901 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263457   ⟹   XP_063119527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8731,043,561 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263458   ⟹   XP_063119528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,822,900 - 31,058,888 (+)NCBI
RefSeq Acc Id: XM_063263459   ⟹   XP_063119529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,781,452 - 31,058,888 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101554 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241323 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450325 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450329 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935001 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935002 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935004 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935005 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935007 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935009 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119516 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119517 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119518 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119519 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119520 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119521 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119522 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119523 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119524 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119525 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119526 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119527 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119528 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119529 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM16878 (Get FASTA)   NCBI Sequence Viewer  
  EDM16879 (Get FASTA)   NCBI Sequence Viewer  
  EDM16880 (Get FASTA)   NCBI Sequence Viewer  
  EDM16881 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010316.4
  ENSRNOP00000074786.2
  ENSRNOP00000076849.1
  ENSRNOP00000077448.1
  ENSRNOP00000079968.1
  ENSRNOP00000081540.1
RefSeq Acc Id: NP_001101554   ⟸   NM_001108084
- UniProtKB: D3ZLE2 (UniProtKB/TrEMBL),   A6IG18 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241323   ⟸   XM_006241261
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZPM9 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450325   ⟸   XM_017594836
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K8Y7 (UniProtKB/TrEMBL),   A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450329   ⟸   XM_017594840
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K8Y7 (UniProtKB/TrEMBL),   A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074786   ⟸   ENSRNOT00000080291
Ensembl Acc Id: ENSRNOP00000010316   ⟸   ENSRNOT00000010316
RefSeq Acc Id: XP_038935001   ⟸   XM_039079073
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935002   ⟸   XM_039079074
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935005   ⟸   XM_039079077
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935004   ⟸   XM_039079076
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935009   ⟸   XM_039079081
- Peptide Label: isoform X4
- UniProtKB: A6IG20 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935007   ⟸   XM_039079079
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZPM9 (UniProtKB/TrEMBL),   A0A0G2K8Y7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079968   ⟸   ENSRNOT00000095728
Ensembl Acc Id: ENSRNOP00000076849   ⟸   ENSRNOT00000094886
Ensembl Acc Id: ENSRNOP00000081540   ⟸   ENSRNOT00000102476
Ensembl Acc Id: ENSRNOP00000077448   ⟸   ENSRNOT00000101181
RefSeq Acc Id: XP_063119529   ⟸   XM_063263459
- Peptide Label: isoform X4
- UniProtKB: A6IG20 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119523   ⟸   XM_063263453
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119522   ⟸   XM_063263452
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119520   ⟸   XM_063263450
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119521   ⟸   XM_063263451
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119528   ⟸   XM_063263458
- Peptide Label: isoform X4
- UniProtKB: A6IG20 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119526   ⟸   XM_063263456
- Peptide Label: isoform X4
- UniProtKB: A6IG20 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119519   ⟸   XM_063263449
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119517   ⟸   XM_063263447
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119518   ⟸   XM_063263448
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y957 (UniProtKB/TrEMBL),   A6IG16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119525   ⟸   XM_063263455
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119524   ⟸   XM_063263454
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119516   ⟸   XM_063263446
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119527   ⟸   XM_063263457
- Peptide Label: isoform X4
- UniProtKB: A6IG20 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLE2-F1-model_v2 AlphaFold D3ZLE2 1-477 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695156
Promoter ID:EPDNEW_R5680
Type:initiation region
Name:Tmcc3_1
Description:transmembrane and coiled-coil domain family 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0735,472,104 - 35,472,164EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307241 AgrOrtholog
BioCyc Gene G2FUF-34370 BioCyc
Ensembl Genes ENSRNOG00000007713 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010316.6 UniProtKB/TrEMBL
  ENSRNOT00000080291.2 UniProtKB/TrEMBL
  ENSRNOT00000094886.1 UniProtKB/TrEMBL
  ENSRNOT00000095728.1 UniProtKB/TrEMBL
  ENSRNOT00000101181.1 UniProtKB/TrEMBL
  ENSRNOT00000102476.1 UniProtKB/TrEMBL
InterPro Predicted_TM_coiled-coil_2 UniProtKB/TrEMBL
KEGG Report rno:314751 UniProtKB/TrEMBL
NCBI Gene 314751 ENTREZGENE
PANTHER PTHR17613 UniProtKB/TrEMBL
  TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3 UniProtKB/TrEMBL
Pfam Tmemb_cc2 UniProtKB/TrEMBL
PhenoGen Tmcc3 PhenoGen
RatGTEx ENSRNOG00000007713 RatGTEx
UniProt A0A0G2K8Y7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y957 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZJH3_RAT UniProtKB/TrEMBL
  A0A8I5ZPM9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT53 ENTREZGENE, UniProtKB/TrEMBL
  A6IG16 ENTREZGENE, UniProtKB/TrEMBL
  A6IG18 ENTREZGENE, UniProtKB/TrEMBL
  A6IG20 ENTREZGENE, UniProtKB/TrEMBL
  D3ZLE2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Tmcc3  transmembrane and coiled-coil domain family 3  Tmcc3  transmembrane and coiled coil domains 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Tmcc3  transmembrane and coiled coil domains 3  Tmcc3_predicted  transmembrane and coiled-coil domain family 3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tmcc3_predicted  transmembrane and coiled-coil domain family 3 (predicted)  RGD1307241_predicted  similar to RIKEN cDNA C630016B22 gene (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1307241_predicted  similar to RIKEN cDNA C630016B22 gene (predicted)  LOC314751_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314751_predicted  similar to RIKEN cDNA C630016B22 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL