Slc39a4 (solute carrier family 39 member 4) - Rat Genome Database

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Gene: Slc39a4 (solute carrier family 39 member 4) Rattus norvegicus
Analyze
Symbol: Slc39a4
Name: solute carrier family 39 member 4
RGD ID: 1306701
Description: Predicted to enable several functions, including monoatomic cation transmembrane transporter activity; zinc ion binding activity; and zinc ion sensor activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion import across plasma membrane. Predicted to act upstream of or within cellular response to zinc ion starvation. Predicted to be located in apical plasma membrane and recycling endosome membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in acrodermatitis enteropathica. Orthologous to human SLC39A4 (solute carrier family 39 member 4); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC300051; MGC156705; solute carrier family 39 (zinc transporter), member 4; zinc transporter ZIP4; ZIP-4; zrt- and Irt-like protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,214,017 - 110,218,202 (-)NCBIGRCr8
mRatBN7.27108,333,368 - 108,337,553 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,333,381 - 108,337,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,075,214 - 110,079,418 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,298,788 - 112,302,992 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,259,628 - 112,263,832 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,675,718 - 117,682,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,675,720 - 117,680,004 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,663,813 - 117,667,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,661,925 - 114,666,098 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,696,147 - 114,700,327 (-)NCBI
Celera7104,683,583 - 104,687,756 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
irinotecan  (EXP)
lead diacetate  (EXP)
leflunomide  (EXP)
Licochalcone B  (ISO)
methimazole  (EXP)
methyl beta-cyclodextrin  (ISO)
methyl methanesulfonate  (ISO)
N(4)-hydroxycytidine  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (ISO)
nickel dichloride  (EXP)
nimesulide  (EXP)
oxycodone  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sucrose  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (EXP)
triptonide  (ISO)
trovafloxacin  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc dichloride  (EXP,ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
apical plasma membrane  (IEA,ISO,ISS)
cytoplasmic vesicle  (ISO,ISS)
plasma membrane  (IBA,ISO,ISS)
recycling endosome membrane  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Kury S, etal., Nat Genet. 2002 Jul;31(3):239-40. Epub 2002 Jun 17.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:12801924   PMID:14612438   PMID:15358787   PMID:15489334   PMID:19530166   PMID:22242765   PMID:23013362   PMID:23376485   PMID:26702153  


Genomics

Comparative Map Data
Slc39a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,214,017 - 110,218,202 (-)NCBIGRCr8
mRatBN7.27108,333,368 - 108,337,553 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,333,381 - 108,337,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,075,214 - 110,079,418 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,298,788 - 112,302,992 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,259,628 - 112,263,832 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,675,718 - 117,682,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,675,720 - 117,680,004 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,663,813 - 117,667,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,661,925 - 114,666,098 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,696,147 - 114,700,327 (-)NCBI
Celera7104,683,583 - 104,687,756 (-)NCBICelera
Cytogenetic Map7q34NCBI
SLC39A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,412,414 - 144,416,844 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,409,742 - 144,416,844 (-)EnsemblGRCh38hg38GRCh38
GRCh378145,637,798 - 145,642,228 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,608,606 - 145,613,081 (-)NCBINCBI36Build 36hg18NCBI36
Build 348145,608,606 - 145,613,081NCBI
Celera8141,812,232 - 141,816,707 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,751,031 - 140,755,512 (-)NCBIHuRef
CHM1_18145,676,089 - 145,680,570 (-)NCBICHM1_1
T2T-CHM13v2.08145,582,227 - 145,586,657 (-)NCBIT2T-CHM13v2.0
Slc39a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,496,583 - 76,501,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,496,583 - 76,501,584 (-)EnsemblGRCm39 Ensembl
GRCm381576,612,383 - 76,618,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,612,383 - 76,617,384 (-)EnsemblGRCm38mm10GRCm38
MGSCv371576,442,813 - 76,447,282 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,439,638 - 76,444,107 (-)NCBIMGSCv36mm8
Celera1578,105,998 - 78,110,467 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.16NCBI
Slc39a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,040,877 - 3,046,250 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,041,316 - 3,047,419 (-)NCBIChiLan1.0ChiLan1.0
SLC39A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,903,143 - 161,908,026 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,432,188 - 137,437,027 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,178,792 - 141,183,565 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,169,089 - 144,173,517 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,169,089 - 144,173,517 (-)Ensemblpanpan1.1panPan2
SLC39A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,833,073 - 37,838,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,833,156 - 37,838,522 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,794,803 - 37,799,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,307,751 - 38,312,842 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,308,739 - 38,312,970 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,999,570 - 38,004,661 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,108,215 - 38,113,309 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,584,583 - 38,589,678 (-)NCBIUU_Cfam_GSD_1.0
Slc39a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303411,386 - 416,321 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,838,030 - 7,842,262 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,836,612 - 7,842,262 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC39A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4372,660 - 378,516 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14372,681 - 378,519 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24464,005 - 469,123 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC39A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,622,100 - 138,626,749 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,622,224 - 138,626,376 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,229,126 - 1,234,212 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc39a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,434,169 - 12,438,510 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,433,024 - 12,438,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc39a4
6 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:413
Count of miRNA genes:193
Interacting mature miRNAs:216
Transcripts:ENSRNOT00000040422, ENSRNOT00000071522
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
AU041686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,333,545 - 108,333,844 (+)MAPPERmRatBN7.2
Rnor_6.07117,675,896 - 117,676,194NCBIRnor6.0
Rnor_5.07117,663,979 - 117,664,277UniSTSRnor5.0
RGSC_v3.47114,662,091 - 114,662,389UniSTSRGSC3.4
Celera7104,683,749 - 104,684,047UniSTS
Cytogenetic Map7q34UniSTS
RH131800  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,333,376 - 108,333,556 (+)MAPPERmRatBN7.2
Rnor_6.07117,675,727 - 117,675,906NCBIRnor6.0
Rnor_5.07117,663,810 - 117,663,989UniSTSRnor5.0
RGSC_v3.47114,661,922 - 114,662,101UniSTSRGSC3.4
Celera7104,683,580 - 104,683,759UniSTS
RH 3.4 Map7795.3UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 44 113 91 90 59 25 59 6 212 91 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000040422   ⟹   ENSRNOP00000047376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,333,381 - 108,337,553 (-)Ensembl
Rnor_6.0 Ensembl7117,675,720 - 117,680,004 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000071522   ⟹   ENSRNOP00000066561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,333,381 - 108,337,553 (-)Ensembl
Rnor_6.0 Ensembl7117,676,948 - 117,679,219 (-)Ensembl
RefSeq Acc Id: NM_001077669   ⟹   NP_001071137
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,214,017 - 110,218,202 (-)NCBI
mRatBN7.27108,333,368 - 108,337,553 (-)NCBI
Rnor_6.07117,675,730 - 117,679,903 (-)NCBI
Rnor_5.07117,663,813 - 117,667,986 (-)NCBI
RGSC_v3.47114,661,925 - 114,666,098 (-)RGD
Celera7104,683,583 - 104,687,756 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001071137 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0JPN2 (Get FASTA)   NCBI Sequence Viewer  
  AAI27515 (Get FASTA)   NCBI Sequence Viewer  
  EDM15958 (Get FASTA)   NCBI Sequence Viewer  
  EDM15959 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047376.4
  ENSRNOP00000066561.3
RefSeq Acc Id: NP_001071137   ⟸   NM_001077669
- Peptide Label: precursor
- UniProtKB: A0JPN2 (UniProtKB/Swiss-Prot),   A0A0H2UHY4 (UniProtKB/TrEMBL),   A6HSB3 (UniProtKB/TrEMBL),   M0RAL0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066561   ⟸   ENSRNOT00000071522
Ensembl Acc Id: ENSRNOP00000047376   ⟸   ENSRNOT00000040422
Protein Domains
Zinc transporter ZIP4 N-terminal   Zinc transporter ZIP4/12 EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0JPN2-F1-model_v2 AlphaFold A0JPN2 1-656 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695430
Promoter ID:EPDNEW_R5953
Type:multiple initiation site
Name:Slc39a4_1
Description:solute carrier family 39 member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07117,679,894 - 117,679,954EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306701 AgrOrtholog
BioCyc Gene G2FUF-32917 BioCyc
Ensembl Genes ENSRNOG00000014314 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040422.6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOT00000071522.3 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7100017 IMAGE-MGC_LOAD
InterPro ZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZIP4_12_EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZIP4_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZIP_Transporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:300051 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156705 IMAGE-MGC_LOAD
NCBI Gene 300051 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 39 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC TRANSPORTER ZIP4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_Zip UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zip UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZIP4_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc39a4 PhenoGen
RatGTEx ENSRNOG00000014314 RatGTEx
UniProt A0A0H2UHY4 ENTREZGENE, UniProtKB/TrEMBL
  A0JPN2 ENTREZGENE
  A6HSB3 ENTREZGENE, UniProtKB/TrEMBL
  M0RAL0 ENTREZGENE, UniProtKB/TrEMBL
  S39A4_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc39a4  solute carrier family 39 member 4  Slc39a4  solute carrier family 39 (zinc transporter), member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Slc39a4  solute carrier family 39 (zinc transporter), member 4   Slc39a4_predicted  solute carrier family 39 (zinc transporter), member 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Slc39a4_predicted  solute carrier family 39 (zinc transporter), member 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED