Fam43a (family with sequence similarity 43, member A)

Advanced Search (OLGA)

Gene: Fam43a (family with sequence similarity 43, member A) Rattus norvegicus

Analyze

Symbol:

Fam43a

Name:

family with sequence similarity 43, member A

RGD ID:

1304790

Description:

Orthologous to human FAM43A (family with sequence similarity 43 member A); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC288031; LOC288031; MGC116410; RGD1304790; similar to CG8312-PA

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	83,633,165 - 83,636,313 (-)	NCBI		GRCr8
mRatBN7.2	11	70,128,253 - 70,131,401 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	70,128,253 - 70,131,401 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	78,972,298 - 78,975,446 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	71,609,970 - 71,613,113 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	70,661,406 - 70,664,554 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	73,676,601 - 73,679,003 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	73,676,601 - 73,678,984 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	76,748,265 - 76,750,667 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	72,010,484 - 72,012,886 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	72,068,960 - 72,078,160 (-)	NCBI
Celera	11	128,018 - 130,420 (+)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R)-pantothenic acid (ISO)

1-naphthyl isothiocyanate (EXP)

15-acetyldeoxynivalenol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-hydroxypropanoic acid (ISO)

2-palmitoylglycerol (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (EXP,ISO)

actinomycin D (ISO)

afimoxifene (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

avobenzone (ISO)

azathioprine (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

Benzo[k]fluoranthene (ISO)

beta-lapachone (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

DDE (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

entinostat (ISO)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

genistein (ISO)

gentamycin (EXP)

glycidol (EXP)

hydroquinone (ISO)

lead(0) (ISO)

leflunomide (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

methotrexate (ISO)

methylisothiazolinone (ISO)

N-nitrosodimethylamine (EXP)

nickel sulfate (ISO)

niclosamide (ISO)

Nutlin-3 (ISO)

oxaliplatin (EXP)

ozone (ISO)

panobinostat (ISO)

paracetamol (ISO)

pentanal (ISO)

phenylmercury acetate (ISO)

progesterone (ISO)

propanal (ISO)

quercitrin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

sunitinib (ISO)

temozolomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

tris(2-butoxyethyl) phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Fam43a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	83,633,165 - 83,636,313 (-)	NCBI		GRCr8
mRatBN7.2	11	70,128,253 - 70,131,401 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	70,128,253 - 70,131,401 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	78,972,298 - 78,975,446 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	71,609,970 - 71,613,113 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	70,661,406 - 70,664,554 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	73,676,601 - 73,679,003 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	73,676,601 - 73,678,984 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	76,748,265 - 76,750,667 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	72,010,484 - 72,012,886 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	72,068,960 - 72,078,160 (-)	NCBI
Celera	11	128,018 - 130,420 (+)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

FAM43A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	194,685,883 - 194,689,037 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	194,685,883 - 194,689,037 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	194,406,612 - 194,409,766 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	195,887,911 - 195,891,055 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	195,887,918 - 195,891,061	NCBI
Celera	3	192,820,433 - 192,823,578 (+)	NCBI		Celera
Cytogenetic Map	3	q29	NCBI
HuRef	3	191,784,777 - 191,787,922 (+)	NCBI		HuRef
CHM1_1	3	194,369,331 - 194,372,476 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	197,382,461 - 197,385,616 (+)	NCBI		T2T-CHM13v2.0

Fam43a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	30,418,541 - 30,421,615 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	30,418,541 - 30,421,615 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	30,599,723 - 30,602,797 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	30,599,723 - 30,602,797 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	30,599,809 - 30,602,883 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	30,519,470 - 30,522,502 (+)	NCBI		MGSCv36	mm8
Celera	16	31,114,283 - 31,117,357 (+)	NCBI		Celera
Cytogenetic Map	16	B2	NCBI
cM Map	16	21.34	NCBI

Fam43a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	14,203,879 - 14,205,165 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	14,202,955 - 14,206,087 (-)	NCBI	ChiLan1.0	ChiLan1.0

FAM43A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	192,609,863 - 192,612,030 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	192,614,585 - 192,616,755 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	191,981,521 - 191,984,684 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	202,291,669 - 202,294,824 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	202,292,603 - 202,293,877 (+)	Ensembl	panpan1.1		panPan2

FAM43A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	31,070,520 - 31,073,393 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	31,070,951 - 31,073,312 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	31,101,312 - 31,103,894 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	31,329,672 - 31,332,254 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	31,330,856 - 31,332,208 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	31,123,619 - 31,126,204 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	31,158,810 - 31,161,371 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	31,784,902 - 31,787,487 (-)	NCBI		UU_Cfam_GSD_1.0

Fam43a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	124,110,293 - 124,113,397 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936711	137,281 - 138,570 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936711	136,411 - 139,558 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FAM43A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	131,663,310 - 131,665,439 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	131,662,474 - 131,665,653 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	141,266,879 - 141,269,989 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FAM43A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	88,771,634 - 88,774,770 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	88,772,565 - 88,773,836 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	62,460,502 - 62,463,654 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam43a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	63,205,990 - 63,207,267 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	63,205,027 - 63,208,444 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fam43a
5 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	62
Count of miRNA genes:	55
Interacting mature miRNAs:	57
Transcripts:	ENSRNOT00000002355
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	59802794	82566553	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	45459323	75190161	Rat
634339	Niddm50	Non-insulin dependent diabetes mellitus QTL 50	3.32		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	66422148	86241447	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	19456205	76331918	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	66113321	82169223	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	60346590	86241447	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
1354656	Bvd3	Brain ventricular dilatation QTL 3	3.64	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	69446070	82846715	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
1354593	Stl12	Serum triglyceride level QTL 12	3.36		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	11	66422148	86241447	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	55136729	82993457	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	56351424	86241447	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	59802794	82566545	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
15	11	55	139	115	110	67	31	67	12	256	121	107	45	75	43

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001039002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC099231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002355 ⟹ ENSRNOP00000002355

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	70,128,253 - 70,131,401 (-)	Ensembl
Rnor_6.0 Ensembl	11	73,676,601 - 73,678,984 (-)	Ensembl

RefSeq Acc Id:

NM_001039002 ⟹ NP_001034091

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	83,633,165 - 83,636,313 (-)	NCBI
mRatBN7.2	11	70,128,253 - 70,131,401 (-)	NCBI
Rnor_6.0	11	73,676,601 - 73,679,003 (-)	NCBI
Rnor_5.0	11	76,748,265 - 76,750,667 (-)	NCBI
RGSC_v3.4	11	72,010,484 - 72,012,886 (-)	RGD
Celera	11	128,018 - 130,420 (+)	RGD

Sequence:

show sequence

TTTTTTTTTTTTTTTTTTTCTTTCTTTCTAAGATTGTACCCCAGCCCCTGCGGGGTTCCCAAGC
ACTATCTGGCCTCTCCTGCCTCCATCTTCCTGTCCTGGAGGTCCTCCCAGCTCGAGTTTTATTT
TTCGAGCTTGCCCGGGCAAAGCGACGCCTGGGTTGGTGGCCCTGCGGGGCTCGTACCCCGCGCT
CGGCCACCGCCGCCCAGCCACTCCCGGACGTCCTCCGGAGATGCTGCCGTGGAAGAAGCACAAG
TTCGAGCTGCTGGCCGAGGCGCCGCCGCGGCAGGCGTCCAAGCCTAAGGGCTACGCTGTGAGCC
TGCACTACTCCGCGCTCAGCTCCCTGGCGAGAGCCTGCCCGGAAGGCGCGCTCAGCCGGGTGGG
CAGCATGTTCCGCTCCAAGCGCAAGAAGCTGCACATCACCAGCGAGGACCCCACTTACACTGTG
CTCTACCTGGGGAATGCCACCACCATCCAGGCTCGCGGGGACGGTTGTACTGACCTAGCGGTGG
GCAAGATCTGGAGCAAGAGTGAGGCCGGCCGTCAAGGGACTAAGATGAAGCTGACCGTGAGTGC
GCAAGGCATCCGCATGGTGCATGCCGAGGAACGAGCGCTGCGACGTCCCGGACACCTCTACCTG
CTGCACCGCGTCACCTACTGTGTGGCAGACGCGCGGTTGCCCAAAGTCTTCGCCTGGGTGTACC
GGCATGAGCTGAAGCACAAGGCGGTAATGCTACGCTGCCACGCGGTGCTGGTGTCCAAGCCGGA
GAAGGCTCAGGCCATGGCCCTGCTGCTCTACCAGACGTCAGCCAACGCTCTGGCAGAGTTTAAA
CGTCTCAAGCGGCGGGATGATGCACGTCACCAGCAGCAGGAGTTGGTGGGCGCACACACCATCC
CCTTAGTGCCGCTGCGCAAGCTGCTCTTGCACGGACCTTGCTGCTACAAGCCGCCAGTGGAGCG
TAGCCGCAGCGCTCCCAAGCTGGGCTCCATCACCGAGGACCTGCTTGGGGAACAGCAGGAGGAG
GAGCTGCAGGAAGAAGAAGAAGAGGAGCACCTCGAGGGCTGCCTGGAGGAGGAGGAGGAGGAGG
AGGAAGAAGAAGAGGACCGCGTGGGGGATGGGGATCCAGCAGAGGAAGAGGCTGAGACGCAGAG
GGCGCTGGTGGTGGCCATGCAGTTGGAATGTGAGGACTTGCTGGACCCGCTGGAAAATGGCCAC
GAGGAGGCGTTGGGGGACGGTGGGGTCTCTCTGGGCCCCAGCTCCGGGACACCACTTCCTCTGT
CAGGCTGTGCTTCAGACATGAAGGCCCAACTGTCACAGCTTATTAGTGACCTGGGTGACCTTAG
CTTTGGCAATGACGTGAGCACCCTGGAGTCCGACTTAAGGGTGACACGCCTGTTGTCGGGCGAG
AGCACAGGCAGCGAGAGCTCCATCGAGGGTGGAGGCCTGGACGCCACCTCGGCCAGCCCTGGCA
ACCCATCCGGCCCTGCTGACAGCACCAGCCTAGATGAGCCCTACTCAAGCTAAGCTACCAGAAG
ACTTCTCCGTGCGCTCACTCCCCCCAGCCCTCCACATACACACAGTGGTTCCCCAACAGTAGTT
CTATTCCCCTTAAACTCCAGGAAAGGGAAAATGATGCACTTGAGGCCCTGGGTTTGGAGTTTCC
TGGAGAGCTATTCTCTCTCCAGTTACCCCAGCGCTTTGGCTCTGAGGTGGCTCAGGTTGTGAGC
CGGGAGATGGGGGGCGGGGAAGAAGCACTACAAAGGAAAGAGATAGGCTTTCCAGGGTGGGTGA
GGGAAAGCGGGCTGAAGCTGGAAAAGGCCAAGGGCGGGCTGGAGGTGCCCAGCAGCCGGTTTCC
TGTTTGTGAGGCAGCTGGGGCTTGGGAAGGAGGGGTTAACTTCCTCTCCAGACCCCCTGACTGG
AAGGCCTCTCTCTGTCTTCAATATCTCATTAACAAAGTCACTTTCATAATGTTGAGGCTTTAAT
GCCGCTTACCTGCCCCCAGTTCTTTTGGATATGAGAGCTTGGGCTGTTTACCTCAGACTCAAAC
TCTTGAAAGTATGCCAAATTTCTCAGATAACTCTTTTATGGGGGGCGGAGGGCGGGGTATGAAA
GTTGTGTTTTGTTTACAGTTAAAGAAATCTAATATCTAAGACACACACACACACACAAAAGGAA
TTTTCCTTTAGAAATACACACCTTCCTCATGCCCCAAAGCTCCTACTCCATGATGCTATGTAAA
ATATTTTTGCACCGTTGTGAAGTATTTTTGACTTTTTTTTTTTGTACATATATCTGTGTTCTTG
GAGCCGAATGTTTATATTTCTTTTGCTGTGCAAAAGATAACCTGTAAAATGTTGTTCGGTTGTA
TATATGGAAATGTGTATAAAACATTTTGTTATTTTTTTTGAGCAAAAAAAAAAAAAAAAAAAAA
AAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001034091	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH99231	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002355.6

RefSeq Acc Id:

NP_001034091 ⟸ NM_001039002

- UniProtKB:

Q4KLG0 (UniProtKB/TrEMBL), F1M8K2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKKLHIT
SEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERAL
RRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAMALLLYQTS
ANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITED
LLGEQQEEELQEEEEEEHLEGCLEEEEEEEEEEEDRVGDGDPAEEEAETQRALVVAMQLECEDL
LDPLENGHEEALGDGGVSLGPSSGTPLPLSGCASDMKAQLSQLISDLGDLSFGNDVSTLESDLR
VTRLLSGESTGSESSIEGGGLDATSASPGNPSGPADSTSLDEPYSS

hide sequence

Ensembl Acc Id:

ENSRNOP00000002355 ⟸ ENSRNOT00000002355

Protein Domains

PID

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4KLG0-F1-model_v2	AlphaFold	Q4KLG0	1-430	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304790	AgrOrtholog
BioCyc Gene	G2FUF-21022	BioCyc
Ensembl Genes	ENSRNOG00000001728	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002355.8	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7442928	IMAGE-MGC_LOAD
InterPro	Adapter_Engulfment-Domain	UniProtKB/TrEMBL
	FAM43A/B_PTB	UniProtKB/TrEMBL
	PH_type	UniProtKB/TrEMBL
	PTB/PI_dom	UniProtKB/TrEMBL
KEGG Report	rno:288031	UniProtKB/TrEMBL
MGC_CLONE	MGC:116410	IMAGE-MGC_LOAD
NCBI Gene	288031	ENTREZGENE
PANTHER	PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER	UniProtKB/TrEMBL
	PROTEIN FAM43A	UniProtKB/TrEMBL
Pfam	PID_2	UniProtKB/TrEMBL
PhenoGen	Fam43a	PhenoGen
RatGTEx	ENSRNOG00000001728	RatGTEx
SMART	PTB	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
UniProt	F1M8K2	ENTREZGENE
	Q4KLG0	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1M8K2	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Fam43a	family with sequence similarity 43, member A	RGD1304790	similar to CG8312-PA	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1304790	similar to CG8312-PA	RGD1304790_predicted	similar to CG8312-PA (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1304790_predicted	similar to CG8312-PA (predicted)	LOC288031_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC288031_predicted	similar to CG8312-PA (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - CTD