| 11857055 | TOX | thymocyte selection associated high mobility group box | ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN lymph node development (ortholog); lymphocyte differentiation (ortholog); Peyer's patch development (ortholog); FOUND IN nucleus (inferred) | 8 | 55246933 | 55553839 | Bonobo | 26 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11779807 | TOX2 | TOX high mobility group box family member 2 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN female gonad development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to gonadotropin (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | 20 | 40242893 | 40400054 | Bonobo | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11840435 | TOX3 | TOX high mobility group box family member 3 | ENCODES a protein that exhibits chromatin binding (inferred); chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN calcium-mediated signaling (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cleft Lip with or wit hout Cleft Palate, Nonsyndromic, 7 (ortholog); Liver Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred) | 16 | 32690290 | 32800974 | Bonobo | 26 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11690053 | TOX4 | TOX high mobility group box family member 4 | ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN regulation of transcription elongation by RNA polymerase II (ortholog); FOUND IN chromatin (ortholog) | 14 | 2294892 | 2316901 | Bonobo | 21 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11906044 | LOC100979454 | TOX high mobility group box family member 4-like | | 4 | 104945274 | 104949947 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 12041700 | GUCY2C | guanylate cyclase 2C | ENCODES a protein that exhibits guanylate cyclase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN regulation of cell population proliferation (ortholog); response to toxic substance (ortholog); ASSOCIATE D WITH abdominal obesity-metabolic syndrome (ortholog); Colorectal Neoplasms (ortholog); congenital diarrhea 6 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); plasma membrane (inferred) | 12 | 14608794 | 14687190 | Bonobo | 37 | old_gene_name , description | gene, protein-coding, MODEL [RefSeq] |
| 12001049 | LOC100969124 | anthrax toxin receptor-like | | 10 | 43269844 | 44029825 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11730902 | LOC100989777 | ras-related C3 botulinum toxin substrate 1 | | 6 | 141918410 | 141919483 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11700628 | LOC100972350 | ras-related C3 botulinum toxin substrate 1-like | | 4 | 99709299 | 99709937 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 11787637 | LOC100985182 | ras-related C3 botulinum toxin substrate 1-like | | X | 126569979 | 126570487 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 11838581 | LOC100986696 | ras-related C3 botulinum toxin substrate 1-like | | 6 | 83757671 | 83759345 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 11671162 | LOC100994316 | ras-related C3 botulinum toxin substrate 1-like | | 13 | 22497209 | 22501268 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 11823702 | ANTXR1 | ANTXR cell adhesion molecule 1 | ENCODES a protein that exhibits actin filament binding (inferred); collagen binding (inferred); metal ion binding (inferred); INVOLVED IN blood vessel development (ortholog); negative regulation of extracellular matrix assembly (ortholog); positive regulation of metallopeptidase activity (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); breast cancer (ortholog); colorectal cancer (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); filopodium membrane (inferred) | 2A | 69054253 | 69290554 | Bonobo | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11773787 | ANTXR2 | ANTXR cell adhesion molecule 2 | ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN collagen fibril organization (ortholog); single fertilization (ortholog); uterus development (ortholog); ASSOCIATED WITH ankylosing spondylitis (ortholog); anthrax disease (ortholog); congenital myopathy 1A (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); membrane (inferred) | 4 | 44124282 | 44284949 | Bonobo | 35 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12009118 | ANTXRL | ANTXR like | | 10 | 43928771 | 43971522 | Bonobo | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11890627 | SLC47A1 | solute carrier family 47 member 1 | ENCODES a protein that exhibits amide transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (ortholog); monoatomic cation transport (ortholog); organic cation transport (ortholog); PARTICIPATES I N cisplatin response pathway; metformin pharmacokinetics pathway; ASSOCIATED WITH kidney disease (ortholog); FOUND IN vesicle (ortholog) | 17 | 31532821 | 31577523 | Bonobo | 42 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11977069 | SLC47A2 | solute carrier family 47 member 2 | ENCODES a protein that exhibits antiporter activity (inferred); polyspecific organic cation:proton antiporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN organic cation transport (inferred); proton transmembrane transport (inferred); transmembrane transport (infer red); PARTICIPATES IN metformin pharmacokinetics pathway; FOUND IN membrane (inferred); plasma membrane (inferred) | 17 | 31412990 | 31454667 | Bonobo | 14 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11945782 | RAC1 | Rac family small GTPase 1 | ENCODES a protein that exhibits ATPase binding (ortholog); enzyme binding (ortholog); G protein activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament organization (ortholog); actin filament polymerization (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; azathioprine pharmacodynamics pathway; c-Jun N-terminal kinases MAPK signaling pathway; ASSOCIATED WITH autosomal dominant intellectual developmental disorder 48 (ortholog); breast cancer (ortholog); Cardiomegaly (ortholog); FOUND IN actin filament (ortholog); cell cortex (ortholog); cell projection (ortholog) | 7 | 7039379 | 7068866 | Bonobo | 316 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11819903 | RAC2 | Rac family small GTPase 2 | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); bone resorption (ortholog); cell projection assembly (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Chronic Perio dontitis (ortholog); Disease Progression (ortholog); FOUND IN actin filament (inferred); cytoplasm (inferred); cytosol (inferred) | 22 | 18138517 | 18159023 | Bonobo | 63 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11781046 | RAC3 | Rac family small GTPase 3 | ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell projection assembly (ortholog); cerebral cortex GABAergic interneuron development (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); basal cell carci noma (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell periphery (ortholog); endomembrane system (ortholog); filamentous actin (ortholog) | 17 | 76436264 | 76439492 | Bonobo | 49 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12034311 | TMEM181 | transmembrane protein 181 | ENCODES a protein that exhibits toxic substance binding (inferred); FOUND IN membrane (inferred) | 6 | 156431076 | 156529012 | Bonobo | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 11999817 | ABTB2 | ankyrin repeat and BTB domain containing 2 | ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); FOUND IN nucleoplasm (inferred) | 11 | 34127668 | 34335680 | Bonobo | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 11855552 | AQP10 | aquaporin 10 | ENCODES a protein that exhibits channel activity (inferred); glycerol channel activity (inferred); urea transmembrane transporter activity (inferred); INVOLVED IN glycerol transmembrane transport (inferred); protein homotetramerization (inferred); response to tox >ic substance (inferred); PARTICIPATES IN water transport pathway; FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); membrane (inferred) | 1 | 129677969 | 129682681 | Bonobo | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 11694678 | ARHGAP33 | Rho GTPase activating protein 33 | ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol binding (inferred); protein kinase binding (inferred); INVOLVED IN regulation of dendritic spine morphogenesis (ortholog); response to toxic substance (ortholog); ASSOCIAT ED WITH autism spectrum disorder (ortholog); disease of mental health (ortholog); temporal lobe epilepsy (ortholog); FOUND IN dendritic spine (ortholog); postsynaptic density (ortholog) | 19 | 32704877 | 32710778 | Bonobo | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 12018981 | ASS1 | argininosuccinate synthase 1 | ENCODES a protein that exhibits argininosuccinate synthase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN acute-phase response (ortholog); argininosuccinate metabolic process (ortholog); cellular response to amine stimulus (ortholog); PARTI CIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Acute-Phase Reaction (ortholog); adult-onset type II citrullinemia (ortholog); FOUND IN cell body fiber (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog) | 9 | 101569442 | 101625899 | Bonobo | 126 | description | gene, protein-coding, MODEL [RefSeq] |
| 11748045 | BLMH | bleomycin hydrolase | ENCODES a protein that exhibits aminopeptidase activity (inferred); cysteine-type aminopeptidase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease 1 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | 17 | 26476039 | 26519782 | Bonobo | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 11879212 | CDH13 | cadherin 13 | ENCODES a protein that exhibits adiponectin binding (inferred); beta-catenin binding (inferred); cadherin binding (inferred); INVOLVED IN cellular response to toxic substance (ortholog); cellular response to xenobiotic stimulus (ortholog); ASSOCIATED WITH amphet amine abuse (ortholog); arteriosclerosis (ortholog); Barrett's esophagus (ortholog); FOUND IN GABA-ergic synapse (ortholog); perinuclear region of cytoplasm (ortholog); synapse (ortholog) | 16 | 63255482 | 64418053 | Bonobo | 87 | description | gene, protein-coding, MODEL [RefSeq] |
| 11810364 | CRISPLD2 | cysteine rich secretory protein LCCL domain containing 2 | ENCODES a protein that exhibits glycosaminoglycan binding (inferred); heparin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); lung development (ortholog); ASSOCIATED WITH liver disease (ortholog); lung disease (ortholog); toxic ence phalopathy (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred); transport vesicle (inferred) | 16 | 65488965 | 65578502 | Bonobo | 13 | description | gene, protein-coding, MODEL [RefSeq] |
| 11744115 | CYP2F1 | cytochrome P450 family 2 subfamily F member 1 | ENCODES a protein that exhibits monooxygenase activity (ortholog); INVOLVED IN naphthalene catabolic process (ortholog); response to toxic substance (ortholog); trichloroethylene metabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Experimental Liver Neoplasms (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum membrane (inferred) | 19 | 38124921 | 38137574 | Bonobo | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 11740237 | DHX15 | DEAH-box helicase 15 | ENCODES a protein that exhibits ATP binding (inferred); double-stranded RNA binding (inferred); helicase activity (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN ribosome biogenesis pathway; splice osome pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); basal cell carcinoma (ortholog); epilepsy (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferred) | 4 | 18931119 | 18988048 | Bonobo | 49 | description | gene, protein-coding, MODEL [RefSeq] |
| 11676943 | GFER | growth factor, augmenter of liver regeneration | ENCODES a protein that exhibits flavin-dependent sulfhydryl oxidase activity (ortholog); INVOLVED IN cellular response to actinomycin D (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to toxic substance (ortholog); PARTICIPATES IN intermembrane space assembly pathway of mitochondrial protein import; mitochondrial iron-sulfur cluster export pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); Acute-On-Chronic Liver Failure (ortholog); FOUND IN extracellular space (ortholog) | 16 | 716640 | 720196 | Bonobo | 59 | description | gene, protein-coding, MODEL [RefSeq] |
| 11888119 | GLYAT | glycine-N-acyltransferase | ENCODES a protein that exhibits acyltransferase activity (inferred); glycine N-acyltransferase activity (inferred); glycine N-benzoyltransferase activity (inferred); INVOLVED IN benzoyl-CoA metabolic process (inferred); glycine metabolic process (inferred); response to tox >toxic substance (inferred); FOUND IN mitochondrion (inferred) | 11 | 53963676 | 53985965 | Bonobo | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 11943564 | GSTA4 | glutathione S-transferase alpha 4 | ENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN cellular response to lithium ion (ortholog); response to herbicide (ortholog); response to nicotine (ortholog); PARTICIPATES IN glutathione conjugation pathway; ASSOCIATED WITH arter iosclerosis (ortholog); Burns (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytosol (inferred) | 6 | 52532942 | 52550404 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11933967 | HTR1D | 5-hydroxytryptamine receptor 1D | ENCODES a protein that exhibits serotonin binding (ortholog); INVOLVED IN regulation of synaptic vesicle exocytosis (ortholog); response to toxic substance (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Hypotension (ortholog); obsessive-compulsive dis order (ortholog); FOUND IN glutamatergic synapse (ortholog); neuronal dense core vesicle (ortholog) | 1 | 22378262 | 22403918 | Bonobo | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 11974812 | IDO1 | indoleamine 2,3-dioxygenase 1 | ENCODES a protein that exhibits amino acid binding (ortholog); indoleamine 2,3-dioxygenase activity (ortholog); oxygen binding (ortholog); INVOLVED IN inflammatory response (ortholog); kynurenic acid biosynthetic process (ortholog); L-tryptophan catabolic process to L-kynurenine (ortholog); PARTICIP ATES IN kynurenine metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); Acute Lung Injury (ortholog); Animal Toxoplasmosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); smooth muscle contractile fiber (inferred) | 8 | 39108310 | 39123611 | Bonobo | 89 | description | gene, protein-coding, MODEL [RefSeq] |
| 11938780 | IL20RA | interleukin 20 receptor subunit alpha | ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); INVOLVED IN cytokine-mediated signaling pathway (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); regulation of bone resorption (ortholog); ASSOCIATED WITH Spo ntaneous Abortions (ortholog); toxic shock syndrome (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 6 | 134762355 | 134805937 | Bonobo | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 12012737 | IL20RB | interleukin 20 receptor subunit beta | ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); INVOLVED IN homeostasis of number of cells within a tissue (ortholog); immune response-inhibiting signal transduction (ortholog); inflammatory response to antigenic stimulus (ortholog); ASSOCIAT ED WITH toxic shock syndrome (ortholog); FOUND IN plasma membrane (inferred) | 3 | 133995863 | 134045206 | Bonobo | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 11738170 | IL21 | interleukin 21 | ENCODES a protein that exhibits cytokine activity (inferred); cytokine receptor binding (inferred); interleukin-2 receptor binding (inferred); INVOLVED IN positive regulation of B cell proliferation (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of i nterleukin-10 production (ortholog); ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); Animal Toxoplasmosis (ortholog); anogenital venereal wart (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); plasma membrane (inferred) | 4 | 114795979 | 114806936 | Bonobo | 88 | description | gene, protein-coding, MODEL [RefSeq] |
| 11939345 | IL23A | interleukin 23 subunit alpha | ENCODES a protein that exhibits cytokine activity (inferred); interleukin-23 receptor binding (inferred); INVOLVED IN positive regulation of receptor signaling pathway via JAK-STAT (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); T cell proliferation (ortholog); PART ICIPATES IN interleukin-23 signaling pathway; ASSOCIATED WITH Amebic Liver Abscess (ortholog); Animal Toxoplasmosis (ortholog); atopic dermatitis (ortholog); FOUND IN interleukin-23 receptor complex (ortholog); plasma membrane (ortholog) | 12 | 32575321 | 32576856 | Bonobo | 86 | description | gene, protein-coding, MODEL [RefSeq] |
| 12043423 | IL2RB | interleukin 2 receptor subunit beta | ENCODES a protein that exhibits interleukin-2 binding (ortholog); interleukin-2 receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pat hway; ASSOCIATED WITH allergic disease (ortholog); Animal Toxoplasmosis (ortholog); asthma (ortholog); FOUND IN cell surface (ortholog) | 22 | 18039469 | 18069952 | Bonobo | 54 | description | gene, protein-coding, MODEL [RefSeq] |
| 11979195 | LDLR | low density lipoprotein receptor | ENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN artery development (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN atherosclerosis pathway; ASSO CIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Animal Toxoplasmosis (ortholog); aortic atherosclerosis (ortholog); FOUND IN caveola (ortholog); plasma membrane (ortholog); recycling endosome membrane (ortholog) | 19 | 10640225 | 10683728 | Bonobo | 321 | description | gene, protein-coding, MODEL [RefSeq] |
| 11858708 | LRP5 | LDL receptor related protein 5 | ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN amino acid transport (ortholog); anatomical structure regression (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN altered Wnt signali ng, canonical pathway; N-cadherin signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH autosomal dominant osteopetrosis 1 (ortholog); autosomal dominant polycystic kidney disease (ortholog); BCARD syndrome (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred); plasma membrane (inferred) | 11 | 63396511 | 63534471 | Bonobo | 153 | description | gene, protein-coding, MODEL [RefSeq] |
| 11969005 | LRP6 | LDL receptor related protein 6 | ENCODES a protein that exhibits apolipoprotein binding (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); axis elongation (ortholog); axis elongation involved in somitogenesis (orthol og); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH anodontia (ortholog); autosomal dominant polycystic kidney disease (ortholog); coronary artery disease (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | 12 | 12121411 | 12288590 | Bonobo | 223 | description | gene, protein-coding, MODEL [RefSeq] |
| 11905130 | NEFM | neurofilament medium chain | ENCODES a protein that exhibits protein-containing complex binding (ortholog); signaling receptor binding (ortholog); toxic substance binding (ortholog); INVOLVED IN axo-dendritic transport (ortholog); axon regeneration (ortholog); cellular response to estradiol stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); congenital hypothyroidism (ortholog); FOUND IN axon (ortholog); intermediate filament (ortholog); neurofilament (ortholog) | 8 | 24181335 | 24186701 | Bonobo | 65 | description | gene, protein-coding, MODEL [RefSeq] |
| 12026151 | NR4A2 | nuclear receptor subfamily 4 group A member 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN adult locomotory behavior (ortholog); cellular response to oxidative stress (ortholog); centr al nervous system neuron differentiation (ortholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH Animal Toxoplasmosis (ortholog); Arsenic Poisoning (ortholog); autism spectrum disorder (ortholog); FOUND IN chromatin (ortholog) | 2B | 43584835 | 43593118 | Bonobo | 112 | description | gene, protein-coding, MODEL [RefSeq] |
| 11823762 | P2RX1 | purinergic receptor P2X 1 | ENCODES a protein that exhibits ATP binding (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); insemination (ortholog); monoatomic cation transmembrane transport (ortholog); ASSOCIATED WITH toxic encephalopathy (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); presynaptic active zone membrane (ortholog) | 17 | 3944636 | 3965260 | Bonobo | 71 | description | gene, protein-coding, MODEL [RefSeq] |
| 11922530 | PHAX | phosphorylated adaptor for RNA export | ENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN snRNA export from nucleus (ortholog); ASSOCIATED WITH Hirschsprung's disease (ortholog); FOUND IN neuronal cell body (ortholog) | 5 | 122005976 | 122032326 | Bonobo | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 11722915 | PPP1R9A | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic sub stance (ortholog); ASSOCIATED WITH Experimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog) | 7 | 86863919 | 87251634 | Bonobo | 77 | description | gene, protein-coding, MODEL [RefSeq] |
| 11714007 | PTPN13 | protein tyrosine phosphatase non-receptor type 13 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphatidylinositol 3-kinase regulatory subunit binding (inferred); phosphoprotein phosphatase activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); negative regulation o f excitatory synapse assembly (ortholog); negative regulation of protein phosphorylation (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH breast cancer (ortholog); colon cancer (ortholog); colorectal cancer (ortholog); FOUND IN cell body (ortholog); midbody (ortholog) | 4 | 78893598 | 79118745 | Bonobo | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 11747854 | RNASE6 | ribonuclease A family member 6 | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); nuclease activity (inferred); INVOLVED IN defense response to virus (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); FOUND IN c ytoplasmic vesicle (inferred); extracellular region (inferred); extracellular space (inferred) | 14 | 1642819 | 1644582 | Bonobo | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 12028797 | RORC | RAR related orphan receptor C | ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription coactivator binding (ortholog); INVOLVED IN adipose tissue development (ortholog); alpha-beta T cell differentiation (ortholog); cell differentiation (ortholog); ASSOCIATED WITH advanced sleep phase syndrome (ortholog); Animal Toxoplasmosis (ortholog); bacterial pneumonia (ortholog); FOUND IN external side of plasma membrane (ortholog) | 1 | 127164725 | 127190479 | Bonobo | 83 | description | gene, protein-coding, MODEL [RefSeq] |
| 11858057 | SLC17A3 | solute carrier family 17 member 3 | ENCODES a protein that exhibits efflux transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport (ortholog); urate metabolic process (ort holog); urate transport (ortholog); ASSOCIATED WITH gout (ortholog); FOUND IN apical plasma membrane (ortholog); cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog) | 6 | 25678412 | 25707948 | Bonobo | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 11726005 | SLC22A3 | solute carrier family 22 member 3 | ENCODES a protein that exhibits dopamine:sodium symporter activity (ortholog); spermidine transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN dopamine transport (ortholog); histamine transport (ortholog ); histamine uptake (ortholog); PARTICIPATES IN lamivudine pharmacokinetics pathway; metformin pharmacokinetics pathway; ASSOCIATED WITH Coxsackievirus Infections (ortholog); Kidney Neoplasms (ortholog); myocarditis (ortholog); FOUND IN apical plasma membrane (inferred); basal plasma membrane (inferred); basolateral plasma membrane (inferred) | 6 | 158240390 | 158344338 | Bonobo | 79 | description | gene, protein-coding, MODEL [RefSeq] |
| 11966990 | SLC22A9 | solute carrier family 22 member 9 | ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog); FOUND IN basolateral plasma membrane (infe rred); membrane (inferred) | 11 | 58722649 | 58763800 | Bonobo | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 12014409 | SRSF9 | serine and arginine rich splicing factor 9 | ENCODES a protein that exhibits mRNA binding (inferred); nucleic acid binding (inferred); protein domain specific binding (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCI ATED WITH Experimental Autoimmune Encephalomyelitis (ortholog); human immunodeficiency virus infectious disease (ortholog); urinary bladder cancer (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 12 | 118043325 | 118052107 | Bonobo | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 11693778 | ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | ENCODES a protein that exhibits sialyltransferase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); F OUND IN Golgi membrane (inferred) | 12 | 63972127 | 64112083 | Bonobo | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 11729943 | STING1 | stimulator of interferon response cGAMP interactor 1 | ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP binding (inferred); cyclic-di-GMP binding (inferred); identical protein binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); defense response to virus (ortholog); positive regulation of transcription by RNA polymerase I I (ortholog); ASSOCIATED WITH Animal Toxoplasmosis (ortholog); brucellosis (ortholog); Chediak-Higashi syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | 5 | 134845689 | 134852938 | Bonobo | 132 | description | gene, protein-coding, MODEL [RefSeq] |
| 11791631 | XRCC1 | X-ray repair cross complementing 1 | ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (inferred); ADP-D-ribose modification-dependent protein binding (inferred); damaged DNA binding (inferred); INVOLVED IN base-excision repair (ortholog); DNA damage response (ortholog); DNA repair (ortholog ); PARTICIPATES IN base excision repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH 5 Alpha Fluorouracil Toxicity (ortholog); acute lymphoblastic leukemia (ortholog); asphyxia neonatorum (ortholog); FOUND IN chromatin (inferred); chromosome (inferred); chromosome, telomeric region (inferred) | 19 | 40485052 | 40522188 | Bonobo | 201 | description | gene, protein-coding, MODEL [RefSeq] |