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Pathways
Genes search result for Pan paniscus
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58 records found for search term Tox
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
11857055TOXthymocyte selection associated high mobility group boxENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN lymph node development (ortholog); lymphocyte differentiation (ortholog); Peyer's patch development (ortholog); FOUND IN nucleus (inferred)85524693355553839Bonobo26symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11779807TOX2TOX high mobility group box family member 2ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN female gonad development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to gonadotropin (ortholog); FOUND IN nucleoplasm (inferred);204024289340400054Bonobo15symbol , namegene, protein-coding, MODEL [RefSeq]
11840435TOX3TOX high mobility group box family member 3ENCODES a protein that exhibits chromatin binding (inferred); chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN calcium-mediated signaling (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cleft Lip with or wit163269029032800974Bonobo26symbol , namegene, protein-coding, MODEL [RefSeq]
11690053TOX4TOX high mobility group box family member 4ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN regulation of transcription elongation by RNA polymerase II (ortholog); FOUND IN chromatin (ortholog)1422948922316901Bonobo21symbol , namegene, protein-coding, MODEL [RefSeq]
11906044LOC100979454TOX high mobility group box family member 4-like4104945274104949947Bonobonamegene, pseudo, MODEL [RefSeq]
12041700GUCY2Cguanylate cyclase 2CENCODES a protein that exhibits guanylate cyclase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN regulation of cell population proliferation (ortholog); response to toxic substance (ortholog); ASSOCIATE121460879414687190Bonobo37old_gene_name , descriptiongene, protein-coding, MODEL [RefSeq]
12001049LOC100969124anthrax toxin receptor-like104326984444029825Bonobonamegene, protein-coding, MODEL [RefSeq]
11730902LOC100989777ras-related C3 botulinum toxin substrate 16141918410141919483Bonobonamegene, protein-coding, MODEL [RefSeq]
11700628LOC100972350ras-related C3 botulinum toxin substrate 1-like49970929999709937Bonoboold_gene_name , namegene, pseudo, MODEL [RefSeq]
11787637LOC100985182ras-related C3 botulinum toxin substrate 1-likeX126569979126570487Bonoboold_gene_name , namegene, pseudo, MODEL [RefSeq]
11838581LOC100986696ras-related C3 botulinum toxin substrate 1-like68375767183759345Bonoboold_gene_name , namegene, pseudo, MODEL [RefSeq]
11671162LOC100994316ras-related C3 botulinum toxin substrate 1-like132249720922501268Bonoboold_gene_name , namegene, pseudo, MODEL [RefSeq]
11823702ANTXR1ANTXR cell adhesion molecule 1ENCODES a protein that exhibits actin filament binding (inferred); collagen binding (inferred); metal ion binding (inferred); INVOLVED IN blood vessel development (ortholog); negative regulation of extracellular matrix assembly (ortholog); positive regulation of metallopeptidase activity (ortholog);2A6905425369290554Bonobo43old_gene_namegene, protein-coding, MODEL [RefSeq]
11773787ANTXR2ANTXR cell adhesion molecule 2ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN collagen fibril organization (ortholog); single fertilization (ortholog); uterus development (ortholog); ASSOCIATED WITH ankylosing 44412428244284949Bonobo35old_gene_namegene, protein-coding, MODEL [RefSeq]
12009118ANTXRLANTXR like104392877143971522Bonoboold_gene_namegene, protein-coding, MODEL [RefSeq]
11890627SLC47A1solute carrier family 47 member 1ENCODES a protein that exhibits amide transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (ortholog); monoatomic cation transport (ortholog); organic cation transport (ortholog); PARTICIPATES I173153282131577523Bonobo42old_gene_namegene, protein-coding, MODEL [RefSeq]
11977069SLC47A2solute carrier family 47 member 2ENCODES a protein that exhibits antiporter activity (inferred); polyspecific organic cation:proton antiporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN organic cation transport (inferred); proton transmembrane transport (inferred); transmembrane transport (infer173141299031454667Bonobo14old_gene_namegene, protein-coding, MODEL [RefSeq]
11945782RAC1Rac family small GTPase 1ENCODES a protein that exhibits ATPase binding (ortholog); enzyme binding (ortholog); G protein activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament organization (ortholog); actin filament polymerization (ortholog); PARTICIPATES IN Arf family mediated signaling770393797068866Bonobo316old_gene_namegene, protein-coding, MODEL [RefSeq]
11819903RAC2Rac family small GTPase 2ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); bone resorption (ortholog); cell projection assembly (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Chronic Perio221813851718159023Bonobo63old_gene_namegene, protein-coding, MODEL [RefSeq]
11781046RAC3Rac family small GTPase 3ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell projection assembly (ortholog); cerebral cortex GABAergic interneuron development (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); basal cell carci177643626476439492Bonobo49old_gene_namegene, protein-coding, MODEL [RefSeq]
12034311TMEM181transmembrane protein 181ENCODES a protein that exhibits toxic substance binding (inferred); FOUND IN membrane (inferred)6156431076156529012Bonobo4descriptiongene, protein-coding, MODEL [RefSeq]
11999817ABTB2ankyrin repeat and BTB domain containing 2ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); FOUND IN nucleoplasm (inferred)113412766834335680Bonobo4descriptiongene, protein-coding, MODEL [RefSeq]
11855552AQP10aquaporin 10ENCODES a protein that exhibits channel activity (inferred); glycerol channel activity (inferred); urea transmembrane transporter activity (inferred); INVOLVED IN glycerol transmembrane transport (inferred); protein homotetramerization (inferred); response to tox1129677969129682681Bonobo26descriptiongene, protein-coding, MODEL [RefSeq]
11694678ARHGAP33Rho GTPase activating protein 33ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol binding (inferred); protein kinase binding (inferred); INVOLVED IN regulation of dendritic spine morphogenesis (ortholog); response to toxic substance (ortholog); ASSOCIAT193270487732710778Bonobo31descriptiongene, protein-coding, MODEL [RefSeq]
12018981ASS1argininosuccinate synthase 1ENCODES a protein that exhibits argininosuccinate synthase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN acute-phase response (ortholog); argininosuccinate metabolic process (ortholog); cellular response to amine stimulus (ortholog); PARTI9101569442101625899Bonobo126descriptiongene, protein-coding, MODEL [RefSeq]
11748045BLMHbleomycin hydrolaseENCODES a protein that exhibits aminopeptidase activity (inferred); cysteine-type aminopeptidase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog);172647603926519782Bonobo29descriptiongene, protein-coding, MODEL [RefSeq]
11879212CDH13cadherin 13ENCODES a protein that exhibits adiponectin binding (inferred); beta-catenin binding (inferred); cadherin binding (inferred); INVOLVED IN cellular response to toxic substance (ortholog); cellular response to xenobiotic stimulus (ortholog); ASSOCIATED WITH amphet166325548264418053Bonobo87descriptiongene, protein-coding, MODEL [RefSeq]
11810364CRISPLD2cysteine rich secretory protein LCCL domain containing 2ENCODES a protein that exhibits glycosaminoglycan binding (inferred); heparin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); lung development (ortholog); ASSOCIATED WITH liver disease (ortholog); lung disease (ortholog); toxic ence166548896565578502Bonobo13descriptiongene, protein-coding, MODEL [RefSeq]
11744115CYP2F1cytochrome P450 family 2 subfamily F member 1ENCODES a protein that exhibits monooxygenase activity (ortholog); INVOLVED IN naphthalene catabolic process (ortholog); response to toxic substance (ortholog); trichloroethylene metabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); 193812492138137574Bonobo23descriptiongene, protein-coding, MODEL [RefSeq]
11740237DHX15DEAH-box helicase 15ENCODES a protein that exhibits ATP binding (inferred); double-stranded RNA binding (inferred); helicase activity (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN ribosome biogenesis pathway; splice41893111918988048Bonobo49descriptiongene, protein-coding, MODEL [RefSeq]
11676943GFERgrowth factor, augmenter of liver regenerationENCODES a protein that exhibits flavin-dependent sulfhydryl oxidase activity (ortholog); INVOLVED IN cellular response to actinomycin D (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to toxic substance (ortholog); PARTICIPATES 16716640720196Bonobo59descriptiongene, protein-coding, MODEL [RefSeq]
11888119GLYATglycine-N-acyltransferaseENCODES a protein that exhibits acyltransferase activity (inferred); glycine N-acyltransferase activity (inferred); glycine N-benzoyltransferase activity (inferred); INVOLVED IN benzoyl-CoA metabolic process (inferred); glycine metabolic process (inferred); response to tox115396367653985965Bonobo22descriptiongene, protein-coding, MODEL [RefSeq]
11943564GSTA4glutathione S-transferase alpha 4ENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN cellular response to lithium ion (ortholog); response to herbicide (ortholog); response to nicotine (ortholog); PARTICIPATES IN glutathione conjugation pathway; ASSOCIATED WITH arter65253294252550404Bonobo34descriptiongene, protein-coding, MODEL [RefSeq]
11933967HTR1D5-hydroxytryptamine receptor 1DENCODES a protein that exhibits serotonin binding (ortholog); INVOLVED IN regulation of synaptic vesicle exocytosis (ortholog); response to toxic substance (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Hypotension (ortholog); obsessive-compulsive dis12237826222403918Bonobo36descriptiongene, protein-coding, MODEL [RefSeq]
11974812IDO1indoleamine 2,3-dioxygenase 1ENCODES a protein that exhibits amino acid binding (ortholog); indoleamine 2,3-dioxygenase activity (ortholog); oxygen binding (ortholog); INVOLVED IN inflammatory response (ortholog); kynurenic acid biosynthetic process (ortholog); L-tryptophan catabolic process to L-kynurenine (ortholog); PARTICIP83910831039123611Bonobo89descriptiongene, protein-coding, MODEL [RefSeq]
11938780IL20RAinterleukin 20 receptor subunit alphaENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); INVOLVED IN cytokine-mediated signaling pathway (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); regulation of bone resorption (ortholog); ASSOCIATED WITH Spo6134762355134805937Bonobo12descriptiongene, protein-coding, MODEL [RefSeq]
12012737IL20RBinterleukin 20 receptor subunit betaENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); INVOLVED IN homeostasis of number of cells within a tissue (ortholog); immune response-inhibiting signal transduction (ortholog); inflammatory response to antigenic stimulus (ortholog); ASSOCIAT3133995863134045206Bonobo18descriptiongene, protein-coding, MODEL [RefSeq]
11738170IL21interleukin 21ENCODES a protein that exhibits cytokine activity (inferred); cytokine receptor binding (inferred); interleukin-2 receptor binding (inferred); INVOLVED IN positive regulation of B cell proliferation (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of i4114795979114806936Bonobo88descriptiongene, protein-coding, MODEL [RefSeq]
11939345IL23Ainterleukin 23 subunit alphaENCODES a protein that exhibits cytokine activity (inferred); interleukin-23 receptor binding (inferred); INVOLVED IN positive regulation of receptor signaling pathway via JAK-STAT (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); T cell proliferation (ortholog); PART123257532132576856Bonobo86descriptiongene, protein-coding, MODEL [RefSeq]
12043423IL2RBinterleukin 2 receptor subunit betaENCODES a protein that exhibits interleukin-2 binding (ortholog); interleukin-2 receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pat221803946918069952Bonobo54descriptiongene, protein-coding, MODEL [RefSeq]
11979195LDLRlow density lipoprotein receptorENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN artery development (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN atherosclerosis pathway; ASSO191064022510683728Bonobo321descriptiongene, protein-coding, MODEL [RefSeq]
11858708LRP5LDL receptor related protein 5ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN amino acid transport (ortholog); anatomical structure regression (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN altered Wnt signali116339651163534471Bonobo153descriptiongene, protein-coding, MODEL [RefSeq]
11969005LRP6LDL receptor related protein 6ENCODES a protein that exhibits apolipoprotein binding (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); axis elongation (ortholog); axis elongation involved in somitogenesis (orthol121212141112288590Bonobo223descriptiongene, protein-coding, MODEL [RefSeq]
11905130NEFMneurofilament medium chainENCODES a protein that exhibits protein-containing complex binding (ortholog); signaling receptor binding (ortholog); toxic substance binding (ortholog); INVOLVED IN axo-dendritic transport (ortholog); axon regeneration (ortholog); cellular response to estradiol82418133524186701Bonobo65descriptiongene, protein-coding, MODEL [RefSeq]
12026151NR4A2nuclear receptor subfamily 4 group A member 2ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN adult locomotory behavior (ortholog); cellular response to oxidative stress (ortholog); centr2B4358483543593118Bonobo112descriptiongene, protein-coding, MODEL [RefSeq]
11823762P2RX1purinergic receptor P2X 1ENCODES a protein that exhibits ATP binding (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); insemination (ortholog); monoatomic cation transmembrane transport (ortholog); 1739446363965260Bonobo71descriptiongene, protein-coding, MODEL [RefSeq]
11922530PHAXphosphorylated adaptor for RNA exportENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN snRNA export from nucleus (ortholog); ASSOCIATED WITH Hirschsprung's disease (ortholog); FOUND IN neuronal cell body (ortholog)5122005976122032326Bonobo18descriptiongene, protein-coding, MODEL [RefSeq]
11722915PPP1R9Aprotein phosphatase 1 regulatory subunit 9AENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic sub78686391987251634Bonobo77descriptiongene, protein-coding, MODEL [RefSeq]
11714007PTPN13protein tyrosine phosphatase non-receptor type 13ENCODES a protein that exhibits hydrolase activity (inferred); phosphatidylinositol 3-kinase regulatory subunit binding (inferred); phosphoprotein phosphatase activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); negative regulation o47889359879118745Bonobo74descriptiongene, protein-coding, MODEL [RefSeq]
11747854RNASE6ribonuclease A family member 6ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); nuclease activity (inferred); INVOLVED IN defense response to virus (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); FOUND IN c1416428191644582Bonobo26descriptiongene, protein-coding, MODEL [RefSeq]
12028797RORCRAR related orphan receptor CENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription coactivator binding (ortholog); INVOLVED IN adipose tissue development (ortholog); alpha-beta T cell differentiation (ortholog); cell differentiation (ortholog); ASSOCIATED1127164725127190479Bonobo83descriptiongene, protein-coding, MODEL [RefSeq]
11858057SLC17A3solute carrier family 17 member 3ENCODES a protein that exhibits efflux transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport (ortholog); urate metabolic process (ort62567841225707948Bonobo17descriptiongene, protein-coding, MODEL [RefSeq]
11726005SLC22A3solute carrier family 22 member 3ENCODES a protein that exhibits dopamine:sodium symporter activity (ortholog); spermidine transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN dopamine transport (ortholog); histamine transport (ortholog6158240390158344338Bonobo79descriptiongene, protein-coding, MODEL [RefSeq]
11966990SLC22A9solute carrier family 22 member 9ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog); FOUND IN basolateral plasma membrane (infe115872264958763800Bonobo15descriptiongene, protein-coding, MODEL [RefSeq]
12014409SRSF9serine and arginine rich splicing factor 9ENCODES a protein that exhibits mRNA binding (inferred); nucleic acid binding (inferred); protein domain specific binding (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCI12118043325118052107Bonobo28descriptiongene, protein-coding, MODEL [RefSeq]
11693778ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENCODES a protein that exhibits sialyltransferase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); F126397212764112083Bonobo18descriptiongene, protein-coding, MODEL [RefSeq]
11729943STING1stimulator of interferon response cGAMP interactor 1ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP binding (inferred); cyclic-di-GMP binding (inferred); identical protein binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); defense response to virus (ortholog); positive regulation of transcription by RNA polymerase I5134845689134852938Bonobo132descriptiongene, protein-coding, MODEL [RefSeq]
11791631XRCC1X-ray repair cross complementing 1ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (inferred); ADP-D-ribose modification-dependent protein binding (inferred); damaged DNA binding (inferred); INVOLVED IN base-excision repair (ortholog); DNA damage response (ortholog); DNA repair (ortholog194048505240522188Bonobo201descriptiongene, protein-coding, MODEL [RefSeq]