TOX (thymocyte selection associated high mobility group box) - Rat Genome Database

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Gene: TOX (thymocyte selection associated high mobility group box) Pan paniscus
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Symbol: TOX
Name: thymocyte selection associated high mobility group box
RGD ID: 11857055
Description: ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN lymph node development (ortholog); lymphocyte differentiation (ortholog); Peyer's patch development (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thymocyte selection-associated high mobility group box protein TOX
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2774,489,654 - 74,795,117 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1850,142,418 - 50,449,169 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0855,246,933 - 55,553,839 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1856,913,312 - 57,219,640 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl856,922,773 - 57,219,410 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TOX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2774,489,654 - 74,795,117 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1850,142,418 - 50,449,169 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0855,246,933 - 55,553,839 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1856,913,312 - 57,219,640 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl856,922,773 - 57,219,410 (-)Ensemblpanpan1.1panPan2
TOX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38858,805,412 - 59,119,147 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl858,805,412 - 59,119,147 (-)EnsemblGRCh38hg38GRCh38
GRCh37859,717,971 - 60,031,706 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36859,880,531 - 60,194,321 (-)NCBINCBI36Build 36hg18NCBI36
Celera855,710,971 - 56,023,242 (-)NCBICelera
Cytogenetic Map8q12.1NCBI
HuRef855,205,353 - 55,519,346 (-)NCBIHuRef
CHM1_1859,770,293 - 60,083,901 (-)NCBICHM1_1
T2T-CHM13v2.0859,226,626 - 59,540,470 (-)NCBIT2T-CHM13v2.0
Tox
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3946,686,353 - 6,991,557 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl46,686,353 - 6,991,557 (-)EnsemblGRCm39 Ensembl
GRCm3846,686,353 - 6,991,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl46,686,353 - 6,991,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv3746,614,533 - 6,917,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3646,614,605 - 6,917,870 (-)NCBIMGSCv36mm8
Celera46,590,011 - 6,896,370 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.04NCBI
Tox
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8524,672,487 - 24,968,754 (-)NCBIGRCr8
mRatBN7.2519,874,994 - 20,171,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl519,874,467 - 20,171,272 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx522,100,634 - 22,397,195 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0523,694,988 - 23,991,309 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0523,475,253 - 23,771,571 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0519,892,698 - 20,189,721 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl519,892,698 - 20,189,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0524,669,152 - 24,965,951 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4520,304,971 - 20,601,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1520,306,623 - 20,780,036 (-)NCBI
Celera519,165,384 - 19,461,532 (-)NCBICelera
Cytogenetic Map5q12NCBI
Tox
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544419,453,783 - 19,795,167 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544419,453,789 - 19,796,419 (+)NCBIChiLan1.0ChiLan1.0
TOX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1299,542,471 - 9,841,759 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl299,544,561 - 9,842,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha299,854,051 - 10,152,715 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0299,627,150 - 9,926,763 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl299,626,943 - 9,926,757 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1299,624,865 - 9,923,979 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0299,750,678 - 10,048,990 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02910,030,303 - 10,329,882 (-)NCBIUU_Cfam_GSD_1.0
Tox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530360,638,151 - 60,938,267 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649613,847,210 - 14,147,886 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649613,847,210 - 14,146,110 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl473,810,290 - 74,115,151 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1473,810,180 - 74,115,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2480,756,768 - 80,906,112 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1854,777,490 - 55,086,819 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl854,776,015 - 54,927,091 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603986,630,447 - 86,940,047 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tox
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474432,865,720 - 33,218,643 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474432,865,781 - 33,218,453 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000049221   ⟹   ENSPPAP00000026388
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl856,922,773 - 57,219,410 (-)Ensembl
RefSeq Acc Id: XM_003809058   ⟹   XP_003809106
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2774,489,654 - 74,795,117 (-)NCBI
NHGRI_mPanPan1850,142,418 - 50,449,169 (-)NCBI
Mhudiblu_PPA_v0855,246,933 - 55,553,839 (-)NCBI
PanPan1.1856,913,312 - 57,219,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008961194   ⟹   XP_008959442
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2774,489,654 - 74,795,112 (-)NCBI
NHGRI_mPanPan1850,142,418 - 50,449,169 (-)NCBI
Mhudiblu_PPA_v0855,246,933 - 55,553,669 (-)NCBI
PanPan1.1856,914,979 - 57,219,569 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055116573   ⟹   XP_054972548
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2774,489,654 - 74,793,592 (-)NCBI
NHGRI_mPanPan1850,142,418 - 50,447,622 (-)NCBI
RefSeq Acc Id: XM_055116574   ⟹   XP_054972549
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2774,489,654 - 74,794,840 (-)NCBI
NHGRI_mPanPan1850,142,418 - 50,448,762 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003809106 (Get FASTA)   NCBI Sequence Viewer  
  XP_008959442 (Get FASTA)   NCBI Sequence Viewer  
  XP_054972548 (Get FASTA)   NCBI Sequence Viewer  
  XP_054972549 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000026388
  ENSPPAP00000026388.1
RefSeq Acc Id: XP_003809106   ⟸   XM_003809058
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B9Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008959442   ⟸   XM_008961194
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B9Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000026388   ⟸   ENSPPAT00000049221
RefSeq Acc Id: XP_054972549   ⟸   XM_055116574
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B9Y0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054972548   ⟸   XM_055116573
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B9Y0 (UniProtKB/TrEMBL)
Protein Domains
HMG box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036301 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049221.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
NCBI Gene TOX ENTREZGENE
PANTHER AGAP000281-PA UniProtKB/TrEMBL
  THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
PRINTS HIGHMOBLTY12 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A2R9B9Y0 ENTREZGENE, UniProtKB/TrEMBL