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51 records found for search term Sms
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1345734SMSspermine synthaseThis gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson SyndromX2194070921994837Human246symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1557826Smsspermine synthasePredicted to enable spermine synthase activity. Acts upstream of or within spermine metabolic process. Is expressed in several structures, including central nervous system; ganglia; limb; respiratory system; and tooth. Human ortholog(s) of this gene implicated in anxiety disorder and syndromic X-linX156226847156275283Mouse148symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1564826Smsspermine synthaseENCODES a protein that exhibits spermine synthase activity; INVOLVED IN spermine biosynthetic process; spermine metabolic process (ortholog); PARTICIPATES IN spermine metabolic pathway; methionine cycle/metabolic pathway; polyamine metabolic pathway; ASSOCIATED WITH anxiety disorder (ortholog); DeveX4133169341387713Rat119symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
9044410Smsspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dNW_00495550922775012328612Chinchilla22symbolgene, protein-coding, MODEL [RefSeq]
11922425SMSspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dX1457143214625601Bonobo29symbolgene, protein-coding, MODEL [RefSeq]
12323985SMSspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dX1774902017803351Dog29symbolgene, protein-coding, MODEL [RefSeq]
12642188Smsspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dNW_00493662423455732402157Squirrel31symbolgene, protein-coding, MODEL [RefSeq]
13947556SMSspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dPig31symbolgene, protein-coding, MODEL [RefSeq]
14388488SmsFlysymbolgene, null
18363849SMSspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dGreen Monkey31symbolgene, protein-coding, MODEL [RefSeq]
18902871Smsspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dNaked Mole-Rat29symbolgene, protein-coding, MODEL [RefSeq]
155232694smsTropical Clawed Frogsymbolgene, null
626112523Smsspermine synthaseENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH anxiety dBlack Rat22symbolgene, protein-coding, MODEL [RefSeq]
14387485sms-1Roundwormsymbolgene, null
25825180sms-2Roundwormsymbolgene, null
598152333sms-2Roundwormsymbolgene, null
14387486sms-3Roundwormsymbolgene, null
152177569sms-5Roundwormsymbolgene, null
155232693sms.LAfrican Clawed Frogsymbolgene, null
2298745Sms-psspermine synthase, pseudogeneX6181873461820243Mousesymbol , PhenoGen , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
7577342Sms-ps1spermine synthase, pseudogene 18114842988114847431Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
1585184Sms-ps2spermine synthase, pseudogene 2INTERACTS WITH (+)-schisandrin B; tetrachloromethane3163403896163405478Rat3symbol , PhenoGen , old_gene_symbolgene, pseudo, VALIDATED [RefSeq]
1318304RAI1retinoic acid induced 1This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. The protein encoded by this gene includes a polymorphic polyglutamine tract in the N-terminal domain. Expression o171768145817811453Human398old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
737192Sstr1somatostatin receptor 1Enables somatostatin receptor activity. Acts upstream of or within cellular response to leukemia inhibitory factor; glutamate receptor signaling pathway; and neuropeptide signaling pathway. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; re125825852458262822Mouse123old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1552204Sstr2somatostatin receptor 2The protein encoded by this gene is a receptor for somatostatin, which acts at many sites to inhibit the release of several hormones and other secretory proteins. The encoded protein is a member of the superfamily of receptors having seven transmembrane segments and is involved in many processes, in11113510153113516854Mouse198old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1551363Sstr3somatostatin receptor 3Enables signaling receptor binding activity. Predicted to be involved in neuropeptide signaling pathway. Located in ciliary membrane; neuron projection; and non-motile cilium. Is expressed in several structures, including central nervous system; cochlea; gallbladder; genitourinary system; and gut. O157842121478433565Mouse127old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
735551Sstr4somatostatin receptor 4Predicted to enable neuropeptide binding activity and somatostatin receptor activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of arachidonate secretion; and regulation of signal transduction. Predicted to be active in neuron projec2148237297148238684Mouse107old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
736502Sstr5somatostatin receptor 5Predicted to enable neuropeptide binding activity and somatostatin receptor activity. Acts upstream of or within glucose homeostasis and regulation of insulin secretion. Located in plasma membrane. Is expressed in brain; cochlea; cochlear duct epithelium; cochlear ganglion; and organ of Corti. Human172570884925716262Mouse99old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
25824857SMSP1SMS pseudogene 1X4771780747719180Humansymbol , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
16559215AC026774.2spermine synthase (SMS) pseudogeneHumannamegene, processed_pseudogene
16558618AC106800.1spermine synthase (SMS) pseudogeneHumannamegene, processed_pseudogene
16551967AL354714.2spermine synthase (SMS) pseudogeneHumannamegene, processed_pseudogene
16555319AL583856.1spermine synthase (SMS) pseudogeneHumannamegene, processed_pseudogene
14379011SMSrFlysymbolgene, null
1559938Smsl1spermine synthase like 1ENCODES a protein that exhibits spermine synthase activity (inferred); transferase activity (inferred); INVOLVED IN polyamine biosynthetic process (inferred); polyamine metabolic process (inferred); spermine biosynthetic process (inferred)138496827584969961Rat10symbol , PhenoGengene, protein-coding, MODEL [RefSeq]
1315069SAMD8sterile alpha motif domain containing 8Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Involved in ceramide biosynthetic process and regulation of ceramide biosynthetic process. Located in cytosol and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]107509959375182123Human97old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1315070Samd8sterile alpha motif domain containing 8Enables ceramide phosphoethanolamine synthase activity. Acts upstream of or within ceramide biosynthetic process and ceramide phosphoethanolamine biosynthetic process. Predicted to be located in cytosol and endoplasmic reticulum. Predicted to be active in Golgi membrane; endoplasmic reticulum membra142180059921848794Mouse105old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1352309SGMS1sphingomyelin synthase 1The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. [provided by RefSeq, Jul 2008]105030560050625184Human180old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1553375Sgms1sphingomyelin synthase 1Enables ceramide phosphoethanolamine synthase activity and sphingomyelin synthase activity. Involved in sphingomyelin biosynthetic process. Acts upstream of or within ceramide biosynthetic process. Predicted to be located in Golgi trans cisterna. Predicted to be active in Golgi membrane; endoplasmic193210012732367285Mouse238old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
14026119SGMS1sphingomyelin synthase 1ENCODES a protein that exhibits ceramide cholinephosphotransferase activity (inferred); ceramide phosphoethanolamine synthase activity (inferred); kinase activity (inferred); INVOLVED IN cellular response to lipopolysaccharide (ortholog); cellular response to tumor necrosis factor (ortholog); ceramiPig36old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
1305778Sgms2sphingomyelin synthase 2ENCODES a protein that exhibits ceramide cholinephosphotransferase activity (ortholog); ceramide phosphoethanolamine synthase activity (ortholog); sphingomyelin synthase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); ceramide phosphoethanolamine biosynthetic process (orth2222567661222641804Rat174old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1331987Sgms2sphingomyelin synthase 2Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthe3131112634131197204Mouse203old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1605563SGMS2sphingomyelin synthase 2Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthe4107824563107915047Human264old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
3761SstsomatostatinENCODES a protein that exhibits identical protein binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN hyperosmotic response; response to acidic pH; response to amino acid; PARTICIPATES IN somatostatin signaling pathway; cimetidine pharmacodynamics pathway; esomeprazole pharmacodynam119046154690462823Rat201old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
734231SSTsomatostatinThe hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled soma3187668912187670394Human211old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
737256SstsomatostatinEnables receptor ligand activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels and somatostatin signaling pathway. Acts upstream of or within regulation of cell migration. Located in extracellular space. Is active in GABA-ergic synapse and cytosol. Is expressed in162370832723710041Mouse242old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1320988SmtnsmoothelinPredicted to enable actin binding activity. Acts upstream of or within negative regulation of systemic arterial blood pressure and positive regulation of cardiac muscle contraction. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in alimentary system; bladder wall; limb; and musc1134675223489337Mouse156old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
3763Sstr2somatostatin receptor 2ENCODES a protein that exhibits PDZ domain binding; somatostatin receptor activity; protein heterodimerization activity (ortholog); INVOLVED IN cellular response to estradiol stimulus; cellular response to glucocorticoid stimulus; cerebellum development; ASSOCIATED WITH Brain Injuries; Experimental 109916335399170519Rat168old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
3764Sstr4somatostatin receptor 4ENCODES a protein that exhibits somatostatin receptor activity; INVOLVED IN cell migration; cellular response to glucocorticoid stimulus; forebrain development; PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED3156307992156309855Rat95old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
3765Sstr5somatostatin receptor 5ENCODES a protein that exhibits somatostatin receptor activity; INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; cellular response to glucocorticoid stimulus; glucose homeostasis (ortholog); PARTICIPATES IN bipolar disorder pathway; ASSOCIATED WITH Experimental 101501020915017469Rat79old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
620308Sstr3somatostatin receptor 3ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN cellular response to estradiol stimulus; cellular response to glucocorticoid stimulus; cerebellum development; ASSOCIATED WITH Brain Injuries; Experimental Diabetes Mellitus; neuroendocrine tumor (ortholog); FOUND IN 7111973049111980250Rat126old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]