Sms (spermine synthase) - Rat Genome Database

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Gene: Sms (spermine synthase) Mus musculus
Analyze
Symbol: Sms
Name: spermine synthase
RGD ID: 1557826
MGI Page MGI
Description: Predicted to enable spermine synthase activity. Acts upstream of or within spermine metabolic process. Is expressed in several structures, including central nervous system; ganglia; limb; respiratory system; and tooth. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Snyder type. Orthologous to human SMS (spermine synthase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI427066; Gy; gyro; Sp; spermidine aminopropyltransferase; SpmST; SPMSY
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm17927   Gm17929   Gm6292   Gm7270   Gm7333   Gm8234   Gm8952   Sms-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X156,226,847 - 156,275,283 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX156,226,851 - 156,275,283 (-)EnsemblGRCm39 Ensembl
GRCm38X157,443,851 - 157,492,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX157,443,855 - 157,492,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X153,881,886 - 153,929,978 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X152,788,059 - 152,836,139 (-)NCBIMGSCv36mm8
CeleraX140,696,273 - 140,722,448 (-)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX72.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
actinomycin D  (ISO)
Aflatoxin B2 alpha  (ISO)
alpha-Zearalanol  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (ISO)
Bisphenol B  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chloropicrin  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
ethanol  (EXP)
folic acid  (EXP)
furan  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
PhIP  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
prednisolone  (ISO)
propiconazole  (EXP)
rac-lactic acid  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tetrahydropalmatine  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Aminooxy analogues of spermidine as inhibitors of spermine synthase and substrates of hepatic polyamine acetylating activity. Eloranta TO, etal., J Biochem. 1990 Oct;108(4):593-8.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. S-adenosylmethionine in liver health, injury, and cancer. Lu SC and Mato JM, Physiol Rev. 2012 Oct;92(4):1515-42. doi: 10.1152/physrev.00047.2011.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. A perspective of polyamine metabolism. Wallace HM, etal., Biochem J. 2003 Nov 15;376(Pt 1):1-14.
Additional References at PubMed
PMID:9063736   PMID:9467015   PMID:9545633   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11160858   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273  
PMID:14681479   PMID:15459188   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18583422   PMID:18799693   PMID:19001365   PMID:19131104   PMID:19641749   PMID:19859664  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:23870131   PMID:24652767   PMID:27572106   PMID:30973865   PMID:38355793   PMID:38463005  


Genomics

Comparative Map Data
Sms
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X156,226,847 - 156,275,283 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX156,226,851 - 156,275,283 (-)EnsemblGRCm39 Ensembl
GRCm38X157,443,851 - 157,492,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX157,443,855 - 157,492,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X153,881,886 - 153,929,978 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X152,788,059 - 152,836,139 (-)NCBIMGSCv36mm8
CeleraX140,696,273 - 140,722,448 (-)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX72.48NCBI
SMS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X21,940,709 - 21,994,837 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX21,940,709 - 21,994,837 (+)EnsemblGRCh38hg38GRCh38
GRCh37X21,958,827 - 22,012,955 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X21,868,763 - 21,922,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X21,718,498 - 21,772,611NCBI
CeleraX26,079,796 - 26,133,909 (+)NCBICelera
Cytogenetic MapXp22.11NCBI
HuRefX19,699,279 - 19,753,795 (+)NCBIHuRef
CHM1_1X21,989,118 - 22,043,385 (+)NCBICHM1_1
T2T-CHM13v2.0X21,524,038 - 21,578,161 (+)NCBIT2T-CHM13v2.0
Sms
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X41,331,693 - 41,387,713 (+)NCBIGRCr8
mRatBN7.2X37,516,949 - 37,572,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX37,516,931 - 37,570,822 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX38,715,556 - 38,768,732 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X42,182,753 - 42,235,926 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X39,867,459 - 39,920,628 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X40,363,646 - 40,415,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX40,363,646 - 40,415,109 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X40,674,244 - 40,725,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X58,816,210 - 58,870,980 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX38,144,381 - 38,195,833 (+)NCBICelera
Cytogenetic MapXq21NCBI
Sms
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555092,276,878 - 2,329,620 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555092,277,501 - 2,328,612 (+)NCBIChiLan1.0ChiLan1.0
SMS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X23,749,232 - 23,816,094 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X23,752,622 - 23,819,491 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X14,571,432 - 14,625,601 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X21,952,477 - 21,980,209 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX21,949,830 - 21,980,209 (+)Ensemblpanpan1.1panPan2
SMS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X17,749,020 - 17,803,351 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX17,749,530 - 17,802,999 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X17,724,469 - 17,762,827 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X17,741,907 - 17,796,615 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X17,763,366 - 17,818,317 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X17,823,900 - 17,878,940 (+)NCBIUU_Cfam_GSD_1.0
Sms
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X10,755,764 - 10,814,207 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366242,346,018 - 2,401,893 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366242,345,573 - 2,402,157 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX18,118,256 - 18,169,390 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X18,118,332 - 18,169,396 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X19,300,734 - 19,353,814 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X20,418,435 - 20,475,227 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX20,418,494 - 20,476,276 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605622,273,775 - 22,330,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sms
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248296,883,027 - 6,931,389 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248296,883,018 - 6,931,646 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sms
1507 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1323
Count of miRNA genes:631
Interacting mature miRNAs:793
Transcripts:ENSMUST00000112529, ENSMUST00000123770, ENSMUST00000127089, ENSMUST00000145477, ENSMUST00000146026
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX144474380169476592Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX133540040165298595Mouse
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX144474380169476592Mouse
12738421Lfibq17_mliver fibrosis QTL 17 (mouse)X148148453164945064Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX120993165160213038Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX125685149159685269Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse

Markers in Region
AI427066  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,443,921 - 157,444,052UniSTSGRCm38
MGSCv37X153,881,853 - 153,881,984UniSTSGRCm37
CeleraX140,696,240 - 140,696,371UniSTS
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
Whitehead/MRC_RHX1807.89UniSTS
AW524902  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381031,213,502 - 31,213,688UniSTSGRCm38
GRCm38X157,443,917 - 157,444,085UniSTSGRCm38
MGSCv371030,933,308 - 30,933,494UniSTSGRCm37
MGSCv37X153,881,849 - 153,882,017UniSTSGRCm37
CeleraX140,696,236 - 140,696,404UniSTS
Celera1032,139,990 - 32,140,176UniSTS
Cytogenetic MapXF4UniSTS
Cytogenetic Map10A4UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X62,775,668 - 62,776,167UniSTSGRCm38
MGSCv37X153,903,661 - 153,904,010UniSTSGRCm37
MGSCv37X153,907,903 - 153,908,080UniSTSGRCm37
MGSCv37X153,885,242 - 153,885,698UniSTSGRCm37
MGSCv37X153,898,227 - 153,898,469UniSTSGRCm37
MGSCv37X153,930,120 - 153,930,780UniSTSGRCm37
CeleraX49,185,576 - 49,186,075UniSTS
Cytogenetic MapXA6UniSTS
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
cM MapX65.45UniSTS
cM MapX65.45UniSTS
cM MapX65.45UniSTS
cM MapX65.45UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,460,295 - 157,460,537UniSTSGRCm38
MGSCv37X153,898,227 - 153,898,469UniSTSGRCm37
CeleraX140,712,606 - 140,712,848UniSTS
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,465,729 - 157,466,078UniSTSGRCm38
MGSCv37X153,903,661 - 153,904,010UniSTSGRCm37
CeleraX140,718,034 - 140,718,383UniSTS
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,447,310 - 157,447,766UniSTSGRCm38
MGSCv37X153,885,242 - 153,885,698UniSTSGRCm37
CeleraX140,699,629 - 140,700,085UniSTS
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,469,971 - 157,470,148UniSTSGRCm38
MGSCv37X153,907,903 - 153,908,080UniSTSGRCm37
CeleraX140,722,309 - 140,722,486UniSTS
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X157,492,188 - 157,492,848UniSTSGRCm38
MGSCv37X153,930,120 - 153,930,780UniSTSGRCm37
Cytogenetic MapXF4UniSTS
cM MapX65.45UniSTS
Sms  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXF4UniSTS
Cytogenetic MapXA6UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF031486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF136179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y09419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000112529   ⟹   ENSMUSP00000108148
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX156,226,851 - 156,275,283 (-)Ensembl
GRCm38.p6 EnsemblX157,443,855 - 157,492,287 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123770   ⟹   ENSMUSP00000115810
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX156,248,860 - 156,274,368 (-)Ensembl
GRCm38.p6 EnsemblX157,465,864 - 157,491,372 (-)Ensembl
Ensembl Acc Id: ENSMUST00000127089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX156,241,870 - 156,275,040 (-)Ensembl
GRCm38.p6 EnsemblX157,458,874 - 157,492,044 (-)Ensembl
Ensembl Acc Id: ENSMUST00000145477   ⟹   ENSMUSP00000131254
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX156,228,692 - 156,275,062 (-)Ensembl
GRCm38.p6 EnsemblX157,445,696 - 157,492,066 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146026
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX156,238,990 - 156,243,857 (-)Ensembl
GRCm38.p6 EnsemblX157,455,994 - 157,460,861 (-)Ensembl
RefSeq Acc Id: NM_001359185   ⟹   NP_001346114
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X156,226,847 - 156,274,364 (-)NCBI
GRCm38X157,443,851 - 157,491,368 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009214   ⟹   NP_033240
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X156,226,847 - 156,275,283 (-)NCBI
GRCm38X157,443,851 - 157,492,287 (-)NCBI
MGSCv37X153,881,886 - 153,929,978 (-)RGD
CeleraX140,696,273 - 140,722,448 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033240   ⟸   NM_009214
- Peptide Label: isoform 1
- UniProtKB: Q9CT09 (UniProtKB/Swiss-Prot),   Q8C7P4 (UniProtKB/Swiss-Prot),   Q3UDT8 (UniProtKB/Swiss-Prot),   Q3TUP0 (UniProtKB/Swiss-Prot),   Q3TL65 (UniProtKB/Swiss-Prot),   A2AC82 (UniProtKB/Swiss-Prot),   Q9R282 (UniProtKB/Swiss-Prot),   P97355 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346114   ⟸   NM_001359185
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000131254   ⟸   ENSMUST00000145477
Ensembl Acc Id: ENSMUSP00000108148   ⟸   ENSMUST00000112529
Ensembl Acc Id: ENSMUSP00000115810   ⟸   ENSMUST00000123770
Protein Domains
PABS   Spermine synthase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97355-F1-model_v2 AlphaFold P97355 1-366 view protein structure

Promoters
RGD ID:6846392
Promoter ID:MM_KWN:62526
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Spleen
Transcripts:OTTMUST00000046292
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X153,929,194 - 153,929,694 (-)MPROMDB
RGD ID:6846414
Promoter ID:MM_KWN:62527
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Lung,   MEF_B4
Transcripts:ENSMUST00000096351,   ENSMUST00000112529,   OTTMUST00000046293,   OTTMUST00000046295,   XM_001473146_1_GM14680
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X153,929,761 - 153,930,261 (-)MPROMDB
RGD ID:13681708
Promoter ID:EPDNEW_M25003
Type:initiation region
Name:Sms_1
Description:Mus musculus spermine synthase , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X157,492,046 - 157,492,106EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109490 AgrOrtholog
Ensembl Genes ENSMUSG00000071708 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112529 ENTREZGENE
  ENSMUST00000112529.8 UniProtKB/Swiss-Prot
  ENSMUST00000123770.2 UniProtKB/TrEMBL
  ENSMUST00000145477.8 UniProtKB/TrEMBL
Gene3D-CATH 2.30.140.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PABS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PABS_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spermidine_synt_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spermidine_synt_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spermine_synthase_animal UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SpmSyn_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20603 UniProtKB/Swiss-Prot
MGD MGI:109490 ENTREZGENE
NCBI Gene 20603 ENTREZGENE
PANTHER PTHR46315 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPERMINE SYNTHASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Spermine_synt_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spermine_synth UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SpmSyn_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sms PhenoGen
PROSITE PABS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PABS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AC81_MOUSE UniProtKB/TrEMBL
  A2AC82 ENTREZGENE
  E9PZ58_MOUSE UniProtKB/TrEMBL
  P97355 ENTREZGENE
  Q3TL65 ENTREZGENE
  Q3TUP0 ENTREZGENE
  Q3UDT8 ENTREZGENE
  Q8C7P4 ENTREZGENE
  Q9CT09 ENTREZGENE
  Q9R282 ENTREZGENE
  SPSY_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A2AC82 UniProtKB/Swiss-Prot
  Q3TL65 UniProtKB/Swiss-Prot
  Q3TUP0 UniProtKB/Swiss-Prot
  Q3UDT8 UniProtKB/Swiss-Prot
  Q8C7P4 UniProtKB/Swiss-Prot
  Q9CT09 UniProtKB/Swiss-Prot
  Q9R282 UniProtKB/Swiss-Prot