Sms (spermine synthase) - Rat Genome Database

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Gene: Sms (spermine synthase) Heterocephalus glaber
Analyze
Symbol: Sms
Name: spermine synthase
RGD ID: 18902871
Description: ENCODES a protein that exhibits spermine synthase activity (ortholog); INVOLVED IN spermine biosynthetic process (ortholog); spermine metabolic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Developmental Disease (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248296,883,027 - 6,931,389 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248296,883,018 - 6,931,646 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Sms
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248296,883,027 - 6,931,389 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248296,883,018 - 6,931,646 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SMS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X21,940,709 - 21,994,837 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX21,940,709 - 21,994,837 (+)EnsemblGRCh38hg38GRCh38
GRCh37X21,958,827 - 22,012,955 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X21,868,763 - 21,922,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X21,718,498 - 21,772,611NCBI
CeleraX26,079,796 - 26,133,909 (+)NCBICelera
Cytogenetic MapXp22.11NCBI
HuRefX19,699,279 - 19,753,795 (+)NCBIHuRef
CHM1_1X21,989,118 - 22,043,385 (+)NCBICHM1_1
T2T-CHM13v2.0X21,524,038 - 21,578,161 (+)NCBIT2T-CHM13v2.0
Sms
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X156,226,847 - 156,275,283 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX156,226,851 - 156,275,283 (-)EnsemblGRCm39 Ensembl
GRCm38X157,443,851 - 157,492,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX157,443,855 - 157,492,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X153,881,886 - 153,929,978 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X152,788,059 - 152,836,139 (-)NCBIMGSCv36mm8
CeleraX140,696,273 - 140,722,448 (-)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX72.48NCBI
Sms
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X41,331,693 - 41,387,713 (+)NCBIGRCr8
mRatBN7.2X37,516,949 - 37,572,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX37,516,931 - 37,570,822 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX38,715,556 - 38,768,732 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X42,182,753 - 42,235,926 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X39,867,459 - 39,920,628 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X40,363,646 - 40,415,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX40,363,646 - 40,415,109 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X40,674,244 - 40,725,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X58,816,210 - 58,870,980 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX38,144,381 - 38,195,833 (+)NCBICelera
Cytogenetic MapXq21NCBI
Sms
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555092,276,878 - 2,329,620 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555092,277,501 - 2,328,612 (+)NCBIChiLan1.0ChiLan1.0
SMS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X23,749,232 - 23,816,094 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X23,752,622 - 23,819,491 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X14,571,432 - 14,625,601 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X21,952,477 - 21,980,209 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX21,949,830 - 21,980,209 (+)Ensemblpanpan1.1panPan2
SMS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X17,749,020 - 17,803,351 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX17,749,530 - 17,802,999 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X17,724,469 - 17,762,827 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X17,741,907 - 17,796,615 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X17,763,366 - 17,818,317 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X17,823,900 - 17,878,940 (+)NCBIUU_Cfam_GSD_1.0
Sms
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X10,755,764 - 10,814,207 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366242,346,018 - 2,401,893 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366242,345,573 - 2,402,157 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX18,118,256 - 18,169,390 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X18,118,332 - 18,169,396 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X19,300,734 - 19,353,814 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X20,418,435 - 20,475,227 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX20,418,494 - 20,476,276 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605622,273,775 - 22,330,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000002382   ⟹   ENSHGLP00000002333
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248296,883,027 - 6,931,389 (+)Ensembl
RefSeq Acc Id: XM_004866189   ⟹   XP_004866246
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248296,883,018 - 6,931,646 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004866246 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002333
  ENSHGLP00100026483
GenBank Protein JAO00866 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004866246   ⟸   XM_004866189
- UniProtKB: A0A0P6J9B1 (UniProtKB/TrEMBL),   G5C1I5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000002333   ⟸   ENSHGLT00000002382


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001773 Ensembl, ENTREZGENE
  ENSHGLG00100019420 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000002382 ENTREZGENE
  ENSHGLT00100026751 UniProtKB/TrEMBL
Gene3D-CATH 2.30.140.10 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro PABS UniProtKB/TrEMBL
  PABS_CS UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  Spermidine_synt_N UniProtKB/TrEMBL
  Spermidine_synt_N_sf UniProtKB/TrEMBL
  Spermine_synthase_animal UniProtKB/TrEMBL
  SpmSyn_N UniProtKB/TrEMBL
KEGG Report hgl:101696715 UniProtKB/TrEMBL
NCBI Gene Sms ENTREZGENE
PANTHER PTHR46315 UniProtKB/TrEMBL
  SPERMINE SYNTHASE UniProtKB/TrEMBL
Pfam Spermine_synt_N UniProtKB/TrEMBL
  Spermine_synth UniProtKB/TrEMBL
  SpmSyn_N UniProtKB/TrEMBL
PROSITE PABS_1 UniProtKB/TrEMBL
  PABS_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0P6J9B1 ENTREZGENE, UniProtKB/TrEMBL
  G5C1I5 ENTREZGENE, UniProtKB/TrEMBL