Smtn (smoothelin) - Rat Genome Database

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Gene: Smtn (smoothelin) Mus musculus
Analyze
Symbol: Smtn
Name: smoothelin
RGD ID: 1320988
MGI Page MGI
Description: Predicted to enable actin binding activity. Acts upstream of or within negative regulation of systemic arterial blood pressure and positive regulation of cardiac muscle contraction. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of filamentous actin. Predicted to be active in microtubule organizing center. Is expressed in alimentary system; bladder wall; limb; and musculature. Orthologous to human SMTN (smoothelin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: smoothelin A; smsmo
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,467,522 - 3,489,337 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,467,523 - 3,490,612 (-)EnsemblGRCm39 Ensembl
GRCm38113,517,522 - 3,539,292 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,517,523 - 3,540,612 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,417,525 - 3,439,295 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,417,526 - 3,439,242 (-)NCBIMGSCv36mm8
Celera114,008,414 - 4,030,184 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.47NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (EXP)
chlordecone  (EXP)
chlorpyrifos  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cocaine  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
glycidol  (ISO)
inulin  (EXP)
isoprenaline  (EXP)
lead diacetate  (EXP)
methotrexate  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
nitrofen  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
progesterone  (EXP,ISO)
quercetin  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
triptonide  (EXP)
trovafloxacin  (EXP)
urethane  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGD IEA MGD IEA
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10023782   PMID:10349636   PMID:10922068   PMID:10965129   PMID:11042159   PMID:11076861   PMID:11544199   PMID:12477932   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16285958   PMID:16602821   PMID:18678771   PMID:18799693   PMID:21068062   PMID:21267068   PMID:21565611   PMID:21677750   PMID:21803035   PMID:21873635   PMID:21979435   PMID:26206133  
PMID:26930384   PMID:28049658   PMID:28378742   PMID:32325033   PMID:32520726   PMID:37497580  


Genomics

Comparative Map Data
Smtn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,467,522 - 3,489,337 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,467,523 - 3,490,612 (-)EnsemblGRCm39 Ensembl
GRCm38113,517,522 - 3,539,292 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,517,523 - 3,540,612 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,417,525 - 3,439,295 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,417,526 - 3,439,242 (-)NCBIMGSCv36mm8
Celera114,008,414 - 4,030,184 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.47NCBI
SMTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,064,118 - 31,104,624 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,064,105 - 31,104,757 (+)EnsemblGRCh38hg38GRCh38
GRCh372231,460,104 - 31,500,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,807,305 - 29,830,609 (+)NCBINCBI36Build 36hg18NCBI36
Build 342229,801,858 - 29,825,163NCBI
Celera2215,277,437 - 15,300,741 (+)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,439,094 - 14,462,417 (+)NCBIHuRef
CHM1_12231,437,118 - 31,460,447 (+)NCBICHM1_1
T2T-CHM13v2.02231,527,653 - 31,568,123 (+)NCBIT2T-CHM13v2.0
Smtn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,622,223 - 82,644,525 (-)NCBIGRCr8
mRatBN7.21478,398,595 - 78,420,908 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,397,778 - 78,420,886 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,839,785 - 82,862,070 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,079,891 - 84,102,176 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,525,655 - 80,547,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,755,141 - 83,776,871 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,755,142 - 83,776,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,443,088 - 84,464,813 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01480,301,566 - 80,303,230 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,160,580 - 84,182,869 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,179,725 - 84,202,043 (-)NCBI
Celera1477,311,041 - 77,333,331 (-)NCBICelera
Cytogenetic Map14q21NCBI
Smtn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,273,602 - 5,297,604 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,271,615 - 5,294,151 (+)NCBIChiLan1.0ChiLan1.0
SMTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,036,635 - 41,060,211 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,735,328 - 43,758,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,105,016 - 12,128,365 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,942,889 - 29,966,256 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,942,895 - 29,966,256 (+)Ensemblpanpan1.1panPan2
SMTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,085,356 - 24,108,005 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,085,382 - 24,108,540 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,955,752 - 23,978,245 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,468,412 - 24,490,906 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,468,434 - 24,490,906 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,171,777 - 24,194,301 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,433,828 - 24,456,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,495,094 - 24,517,587 (+)NCBIUU_Cfam_GSD_1.0
Smtn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118117,005,130 - 117,028,133 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755264,570 - 289,260 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755264,635 - 285,668 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,879,317 - 47,902,698 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,879,317 - 47,902,700 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,990,987 - 51,014,394 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,972,812 - 13,996,124 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,974,686 - 13,999,061 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,123,501 - 112,146,815 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smtn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,559,026 - 7,585,154 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,559,364 - 7,582,080 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smtn
513 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1943
Count of miRNA genes:578
Interacting mature miRNAs:693
Transcripts:ENSMUST00000020718, ENSMUST00000020721, ENSMUST00000075118, ENSMUST00000110011, ENSMUST00000136243, ENSMUST00000144635, ENSMUST00000151804, ENSMUST00000154861, ENSMUST00000156201, ENSMUST00000170588
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
RH141532  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38113,517,569 - 3,517,763UniSTSGRCm38
MGSCv37113,417,572 - 3,417,766UniSTSGRCm37
Celera114,008,461 - 4,008,655UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map11A2-A3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001159284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001284427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001284428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001284429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001425504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF064236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF132449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI480617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ010305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL713875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW490128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB661878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY724924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK388087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000020718   ⟹   ENSMUSP00000020718
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,467,523 - 3,477,937 (-)Ensembl
GRCm38.p6 Ensembl113,517,523 - 3,527,937 (-)Ensembl
RefSeq Acc Id: ENSMUST00000020721   ⟹   ENSMUSP00000020721
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,467,523 - 3,489,292 (-)Ensembl
GRCm38.p6 Ensembl113,517,523 - 3,539,292 (-)Ensembl
RefSeq Acc Id: ENSMUST00000075118   ⟹   ENSMUSP00000074621
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,467,523 - 3,489,239 (-)Ensembl
GRCm38.p6 Ensembl113,517,523 - 3,539,239 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110011   ⟹   ENSMUSP00000105638
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,467,523 - 3,487,398 (-)Ensembl
GRCm38.p6 Ensembl113,517,523 - 3,537,398 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136243   ⟹   ENSMUSP00000117307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,482,603 - 3,489,251 (-)Ensembl
GRCm38.p6 Ensembl113,532,603 - 3,539,251 (-)Ensembl
RefSeq Acc Id: ENSMUST00000144635
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,470,538 - 3,472,554 (-)Ensembl
GRCm38.p6 Ensembl113,520,538 - 3,522,554 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,484,814 - 3,489,249 (-)Ensembl
GRCm38.p6 Ensembl113,534,814 - 3,539,249 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154861
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,467,523 - 3,489,252 (-)Ensembl
GRCm38.p6 Ensembl113,517,523 - 3,539,252 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156201   ⟹   ENSMUSP00000118750
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,482,460 - 3,490,612 (-)Ensembl
GRCm38.p6 Ensembl113,532,460 - 3,540,612 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170588   ⟹   ENSMUSP00000133155
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,467,523 - 3,489,292 (-)Ensembl
GRCm38.p6 Ensembl113,517,523 - 3,539,292 (-)Ensembl
RefSeq Acc Id: NM_001159284   ⟹   NP_001152756
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,254 (-)NCBI
GRCm38113,517,522 - 3,539,292 (-)NCBI
MGSCv37113,417,525 - 3,439,295 (-)RGD
Celera114,008,414 - 4,030,184 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001284427   ⟹   NP_001271356
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,254 (-)NCBI
GRCm38113,517,522 - 3,539,292 (-)NCBI
Celera114,008,414 - 4,030,184 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001284428   ⟹   NP_001271357
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,254 (-)NCBI
GRCm38113,517,522 - 3,539,292 (-)NCBI
Celera114,008,414 - 4,030,184 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001284429   ⟹   NP_001271358
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,292 (-)NCBI
GRCm38113,517,522 - 3,539,292 (-)NCBI
Celera114,008,414 - 4,030,184 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001425501   ⟹   NP_001412430
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,470,744 - 3,489,254 (-)NCBI
RefSeq Acc Id: NM_001425502   ⟹   NP_001412431
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,477,942 (-)NCBI
RefSeq Acc Id: NM_001425503   ⟹   NP_001412432
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,254 (-)NCBI
RefSeq Acc Id: NM_001425504   ⟹   NP_001412433
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,477,942 (-)NCBI
RefSeq Acc Id: NM_013870   ⟹   NP_038898
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,254 (-)NCBI
GRCm38113,517,522 - 3,539,292 (-)NCBI
MGSCv37113,417,525 - 3,439,295 (-)RGD
Celera114,008,414 - 4,030,184 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514724   ⟹   XP_006514787
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,487,572 (-)NCBI
GRCm38113,517,522 - 3,537,570 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017314586   ⟹   XP_017170075
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,201 (-)NCBI
GRCm38113,517,522 - 3,539,254 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246062   ⟹   XP_030101922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,487,430 (-)NCBI
GRCm38113,517,522 - 3,537,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246063   ⟹   XP_030101923
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,487,430 (-)NCBI
GRCm38113,517,522 - 3,537,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246064   ⟹   XP_030101924
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,471,016 - 3,487,430 (-)NCBI
GRCm38113,521,016 - 3,537,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156747   ⟹   XP_036012640
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,487,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156748   ⟹   XP_036012641
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,487,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156749   ⟹   XP_036012642
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,471,016 - 3,479,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156750   ⟹   XP_036012643
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,467,522 - 3,489,337 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001152756 (Get FASTA)   NCBI Sequence Viewer  
  NP_001271356 (Get FASTA)   NCBI Sequence Viewer  
  NP_001271357 (Get FASTA)   NCBI Sequence Viewer  
  NP_001271358 (Get FASTA)   NCBI Sequence Viewer  
  NP_001412430 (Get FASTA)   NCBI Sequence Viewer  
  NP_001412431 (Get FASTA)   NCBI Sequence Viewer  
  NP_001412432 (Get FASTA)   NCBI Sequence Viewer  
  NP_001412433 (Get FASTA)   NCBI Sequence Viewer  
  NP_038898 (Get FASTA)   NCBI Sequence Viewer  
  XP_006514787 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170075 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101922 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101923 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101924 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012640 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012641 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012642 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012643 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD29628 (Get FASTA)   NCBI Sequence Viewer  
  AAF01480 (Get FASTA)   NCBI Sequence Viewer  
  AAF25577 (Get FASTA)   NCBI Sequence Viewer  
  AAF25578 (Get FASTA)   NCBI Sequence Viewer  
  AAF25579 (Get FASTA)   NCBI Sequence Viewer  
  AAF25580 (Get FASTA)   NCBI Sequence Viewer  
  AAF67392 (Get FASTA)   NCBI Sequence Viewer  
  AAH10599 (Get FASTA)   NCBI Sequence Viewer  
  AAH66192 (Get FASTA)   NCBI Sequence Viewer  
  AAH69836 (Get FASTA)   NCBI Sequence Viewer  
  AAH69839 (Get FASTA)   NCBI Sequence Viewer  
  BAB26278 (Get FASTA)   NCBI Sequence Viewer  
  BAC27188 (Get FASTA)   NCBI Sequence Viewer  
  BAE41853 (Get FASTA)   NCBI Sequence Viewer  
  CAA09076 (Get FASTA)   NCBI Sequence Viewer  
  EDL40433 (Get FASTA)   NCBI Sequence Viewer  
  EDL40434 (Get FASTA)   NCBI Sequence Viewer  
  EDL40435 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020718.5
  ENSMUSP00000020721
  ENSMUSP00000020721.9
  ENSMUSP00000074621
  ENSMUSP00000074621.4
  ENSMUSP00000105638.2
  ENSMUSP00000117307.2
  ENSMUSP00000118750.2
  ENSMUSP00000133155
  ENSMUSP00000133155.2
GenBank Protein Q921U8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_038898   ⟸   NM_013870
- Peptide Label: isoform b
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152756   ⟸   NM_001159284
- Peptide Label: isoform b
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001271356   ⟸   NM_001284427
- Peptide Label: isoform a
- UniProtKB: Q9R253 (UniProtKB/Swiss-Prot),   Q9R0D0 (UniProtKB/Swiss-Prot),   Q9JLU7 (UniProtKB/Swiss-Prot),   Q9JHG8 (UniProtKB/Swiss-Prot),   Q8CD93 (UniProtKB/Swiss-Prot),   Q6NSW1 (UniProtKB/Swiss-Prot),   Q3TCV2 (UniProtKB/Swiss-Prot),   Q9Z0Q2 (UniProtKB/Swiss-Prot),   Q921U8 (UniProtKB/Swiss-Prot),   D3Z3Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001271358   ⟸   NM_001284429
- Peptide Label: isoform c
- UniProtKB: Q921U8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001271357   ⟸   NM_001284428
- Peptide Label: isoform b
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006514787   ⟸   XM_006514724
- Peptide Label: isoform X8
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017170075   ⟸   XM_017314586
- Peptide Label: isoform X4
- UniProtKB: Q9R253 (UniProtKB/Swiss-Prot),   Q9R0D0 (UniProtKB/Swiss-Prot),   Q9JLU7 (UniProtKB/Swiss-Prot),   Q9JHG8 (UniProtKB/Swiss-Prot),   Q8CD93 (UniProtKB/Swiss-Prot),   Q6NSW1 (UniProtKB/Swiss-Prot),   Q3TCV2 (UniProtKB/Swiss-Prot),   Q9Z0Q2 (UniProtKB/Swiss-Prot),   Q921U8 (UniProtKB/Swiss-Prot),   D3Z3Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101922   ⟸   XM_030246062
- Peptide Label: isoform X1
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030101923   ⟸   XM_030246063
- Peptide Label: isoform X2
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030101924   ⟸   XM_030246064
- Peptide Label: isoform X3
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000133155   ⟸   ENSMUST00000170588
RefSeq Acc Id: ENSMUSP00000105638   ⟸   ENSMUST00000110011
RefSeq Acc Id: ENSMUSP00000020718   ⟸   ENSMUST00000020718
RefSeq Acc Id: ENSMUSP00000020721   ⟸   ENSMUST00000020721
RefSeq Acc Id: ENSMUSP00000074621   ⟸   ENSMUST00000075118
RefSeq Acc Id: ENSMUSP00000117307   ⟸   ENSMUST00000136243
RefSeq Acc Id: ENSMUSP00000118750   ⟸   ENSMUST00000156201
RefSeq Acc Id: XP_036012643   ⟸   XM_036156750
- Peptide Label: isoform X9
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036012640   ⟸   XM_036156747
- Peptide Label: isoform X5
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036012641   ⟸   XM_036156748
- Peptide Label: isoform X6
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036012642   ⟸   XM_036156749
- Peptide Label: isoform X7
RefSeq Acc Id: NP_001412432   ⟸   NM_001425503
- Peptide Label: isoform e
RefSeq Acc Id: NP_001412433   ⟸   NM_001425504
- Peptide Label: isoform f
- UniProtKB: D3YVS1 (UniProtKB/TrEMBL),   Q9D7A0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001412431   ⟸   NM_001425502
- Peptide Label: isoform d
- UniProtKB: D3YVS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001412430   ⟸   NM_001425501
- Peptide Label: isoform b
- UniProtKB: D3Z3Q3 (UniProtKB/TrEMBL)
Protein Domains
Calponin-homology (CH)   Smoothelin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q921U8-F1-model_v2 AlphaFold Q921U8 1-923 view protein structure

Promoters
RGD ID:6822173
Promoter ID:MM_KWN:6172
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:OTTMUST00000011169
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36113,422,521 - 3,423,272 (-)MPROMDB
RGD ID:6846905
Promoter ID:MM_ACW:6537
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:SMTN.ISEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36113,424,771 - 3,425,271 (-)MPROMDB
RGD ID:6822175
Promoter ID:MM_KWN:6173
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000020718
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36113,427,571 - 3,428,071 (-)MPROMDB
RGD ID:6822171
Promoter ID:MM_KWN:6177
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:ENSMUST00000110011
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36113,436,829 - 3,437,329 (-)MPROMDB
RGD ID:6822174
Promoter ID:MM_KWN:6178
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001159284,   NM_013870,   OTTMUST00000011167,   OTTMUST00000011168,   OTTMUST00000011170,   OTTMUST00000011171,   UC007HTH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36113,439,014 - 3,439,514 (-)MPROMDB
RGD ID:8673738
Promoter ID:EPDNEW_M14900
Type:multiple initiation site
Name:Smtn_2
Description:Mus musculus smoothelin , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14901  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38113,527,942 - 3,528,002EPDNEW
RGD ID:8673742
Promoter ID:EPDNEW_M14901
Type:multiple initiation site
Name:Smtn_1
Description:Mus musculus smoothelin , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14900  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38113,539,254 - 3,539,314EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354727 AgrOrtholog
Ensembl Genes ENSMUSG00000020439 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020718.10 UniProtKB/TrEMBL
  ENSMUST00000020721 ENTREZGENE
  ENSMUST00000020721.15 UniProtKB/Swiss-Prot
  ENSMUST00000075118 ENTREZGENE
  ENSMUST00000075118.10 UniProtKB/Swiss-Prot
  ENSMUST00000110011.8 UniProtKB/TrEMBL
  ENSMUST00000136243.2 UniProtKB/TrEMBL
  ENSMUST00000154861 ENTREZGENE
  ENSMUST00000156201.8 UniProtKB/TrEMBL
  ENSMUST00000170588 ENTREZGENE
  ENSMUST00000170588.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.418.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMTN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:29856 UniProtKB/Swiss-Prot
MGD MGI:1354727 ENTREZGENE
NCBI Gene 29856 ENTREZGENE
PANTHER CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMOOTHELIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Smoothelin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Smtn PhenoGen
PROSITE PS50021 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00033 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47576 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3YVS1 ENTREZGENE, UniProtKB/TrEMBL
  D3YZ10_MOUSE UniProtKB/TrEMBL
  D3Z3Q3 ENTREZGENE, UniProtKB/TrEMBL
  D3Z525_MOUSE UniProtKB/TrEMBL
  Q3TCV2 ENTREZGENE
  Q6NSW1 ENTREZGENE
  Q8CD93 ENTREZGENE
  Q921U8 ENTREZGENE
  Q9D7A0 ENTREZGENE, UniProtKB/TrEMBL
  Q9JHG8 ENTREZGENE
  Q9JLU7 ENTREZGENE
  Q9R0D0 ENTREZGENE
  Q9R253 ENTREZGENE
  Q9Z0Q2 ENTREZGENE
  SMTN_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TCV2 UniProtKB/Swiss-Prot
  Q6NSW1 UniProtKB/Swiss-Prot
  Q8CD93 UniProtKB/Swiss-Prot
  Q9JHG8 UniProtKB/Swiss-Prot
  Q9JLU7 UniProtKB/Swiss-Prot
  Q9R0D0 UniProtKB/Swiss-Prot
  Q9R253 UniProtKB/Swiss-Prot
  Q9Z0Q2 UniProtKB/Swiss-Prot