| 70490 | Nat1 | N-acetyltransferase 1 | ENCODES a protein that exhibits arylamine N-acetyltransferase activity; INVOLVED IN liver development; response to thyroxine; PARTICIPATES IN caffeine metabolic pathway; ASSOCIATED WITH adenocarcinoma (ortholog); allergic contact dermatitis (ortholog); asthma (ortholog); FOUND IN cytoplasm (inferred ); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione | 16 | 26984882 | 27005194 | Rat | 207 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 735739 | Nat1 | N-acetyl transferase 1 | Enables arylamine N-acetyltransferase activity. Predicted to be located in cytoplasm. Is expressed in several structures, including adrenal gland; brain; genitourinary system; submandibular gland; and thymus. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); contact dermatitis (multiple); leukemia (multiple); and lung disease (multiple). Orthologous to several human genes including NAT2 (N-acetyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 67943620 | 67945183 | Mouse | 209 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1344668 | NAT1 | N-acetyltransferase 1 | This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabo lize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] | 8 | 18170467 | 18223689 | Human | 209 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 11755418 | NAT1 | N-acetyltransferase 1 | ENCODES a protein that exhibits arylamine N-acetyltransferase activity (ortholog); INVOLVED IN liver development (ortholog); response to thyroxine (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); allergic contact dermatitis (ortholog); asthma (ortholog) | 8 | 17425852 | 17439684 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14380964 | NAT1 | | | | | | Yeast | | symbol | gene, null |
| 14383333 | NAT1 | | | | | | Fly | | symbol | gene, null |
| 1313238 | EIF4G2 | eukaryotic translation initiation factor 4 gamma 2 | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-termin al region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] | 11 | 10797046 | 10808926 | Human | 154 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1313239 | Eif4g2 | eukaryotic translation initiation factor 4, gamma 2 | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-termin al region of eIF4G, that contains the binding sites for eIF4A and eIF3; eIF4G in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. Transgene expression of the apolipoprotein B mRNA-editing enzyme (APOBEC-1) causes extensive editing of this mRNA, which could contribute to the potent oncogenesis induced by overexpression of APOBEC-1. In vitro and in vivo studies in human indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. This also appears to be true for mouse. Two alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 7 | 110667192 | 110682237 | Mouse | 173 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 621477 | Eif4g2-ps1 | eukaryotic translation initiation factor 4, gamma 2, pseudogene 1 | pseudogene of the gamma 2 subunit of translation initiation factor Eif4f | 9 | 40542958 | 40546739 | Rat | | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 18476206 | LOC103215401 | arylamine N-acetyltransferase 1 | ENCODES a protein that exhibits arylamine N-acetyltransferase activity (ortholog); INVOLVED IN liver development (ortholog); response to thyroxine (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); allergic contact dermatitis (ortholog); asthma (ortholog) | | | | Green Monkey | 26 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 628620 | Slc38a3 | solute carrier family 38, member 3 | ENCODES a protein that exhibits L-asparagine transmembrane transporter activity; L-asparagine, sodium:proton antiporter activity; L-glutamine transmembrane transporter activity; INVOLVED IN asparagine transmembrane transport; asparagine transport; female pregnancy; PARTICIPATES IN glutamate signalin g pathway; ASSOCIATED WITH Endotoxemia; Experimental Seizures; metabolic acidosis; FOUND IN basolateral plasma membrane; plasma membrane; apical plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 8 | 117202534 | 117220310 | Rat | 266 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 730997 | SLC38A3 | solute carrier family 38 member 3 | Enables L-amino acid transmembrane transporter activity. Involved in carboxylic acid transport. Located in plasma membrane. Implicated in developmental and epileptic encephalopathy 102. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 50205271 | 50221486 | Human | 291 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 730998 | Slc38a3 | solute carrier family 38, member 3 | Enables L-asparagine, sodium:proton antiporter activity; L-glutamine, sodium:proton antiporter activity; and L-histidine, sodium:proton antiporter activity. Involved in carboxylic acid transport and intracellular amino acid homeostasis. Acts upstream of or within several processes, including carboxy lic acid transport; cellular response to potassium ion starvation; and response to acidic pH. Located in apical plasma membrane. Is expressed in several structures, including central nervous system; metanephros; pancreas; pericardium; and retina. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 102. Orthologous to human SLC38A3 (solute carrier family 38 member 3). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 107528353 | 107546167 | Mouse | 268 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 731947 | SLC6A2 | solute carrier family 6 member 2 | This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic in tolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] | 16 | 55655988 | 55706192 | Human | 281 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1306717 | Nat10 | N-acetyltransferase 10 | ENCODES a protein that exhibits DNA polymerase binding (ortholog); mRNA N-acetyltransferase activity (ortholog); N-acetyltransferase activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); positive regulation of translation (ortholog); protein acetylat ion (ortholog); FOUND IN midbody (ortholog); nucleolus (ortholog); small-subunit processome (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; amphetamine | 3 | 110566582 | 110604829 | Rat | 134 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1315495 | Nat10 | N-acetyltransferase 10 | Predicted to enable DNA polymerase binding activity; N-acetyltransferase activity; and tRNA binding activity. Predicted to be involved in several processes, including RNA modification; regulation of centrosome duplication; and regulation of macromolecule biosynthetic process. Predicted to be located in midbody. Predicted to be part of small-subunit processome and telomerase holoenzyme complex. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; clavicle; cranium bone primordium; early conceptus; and skeletal musculature. Orthologous to human NAT10 (N-acetyltransferase 10). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 103551603 | 103593292 | Mouse | 155 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605376 | NAT10 | N-acetyltransferase 10 | The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation, tRNA acetylation, the biosynthesis of 18S rRNA, and the enhancement of nuclear architecture and chromatin organization. [provided by RefSeq, Oct 2016] | 11 | 34105629 | 34146908 | Human | 137 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9005672 | Nat10 | N-acetyltransferase 10 | ENCODES a protein that exhibits DNA polymerase binding (ortholog); mRNA N-acetyltransferase activity (ortholog); N-acetyltransferase activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); positive regulation of translation (ortholog); protein acetylat ion (ortholog); FOUND IN midbody (ortholog); nucleolus (ortholog); small-subunit processome (ortholog) | NW_004955422 | 12085970 | 12122644 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11917953 | NAT10 | N-acetyltransferase 10 | ENCODES a protein that exhibits 18S rRNA cytidine N-acetyltransferase activity (inferred); acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); INVOLVED IN protein acetylation (ortholog); FOUND IN 90S preribosome (inferred); midb ody (inferred); nucleolus (inferred) | 11 | 34082304 | 34127793 | Bonobo | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12300302 | NAT10 | N-acetyltransferase 10 | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); ATP binding (inferred); INVOLVED IN protein acetylation (ortholog); FOUND IN midbody (inferred); nucleolus (inferred); small-subunit processome (inferred) | 18 | 33654701 | 33692642 | Dog | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12600046 | Nat10 | N-acetyltransferase 10 | ENCODES a protein that exhibits DNA polymerase binding (ortholog); mRNA N-acetyltransferase activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); positive regulation of translation (ortholog); protein acetylation (ortholog); FOUND IN midbody (ortholo g); small-subunit processome (ortholog); telomerase holoenzyme complex (ortholog) | NW_004936533 | 3870795 | 3911498 | Squirrel | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14017912 | NAT10 | N-acetyltransferase 10 | ENCODES a protein that exhibits 18S rRNA cytidine N-acetyltransferase activity (inferred); acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); INVOLVED IN protein acetylation (ortholog); FOUND IN midbody (inferred); nucleolus (i nferred); small-subunit processome (inferred) | | | | Pig | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18587989 | NAT10 | N-acetyltransferase 10 | ENCODES a protein that exhibits 18S rRNA cytidine N-acetyltransferase activity (inferred); acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); INVOLVED IN protein acetylation (ortholog); FOUND IN 90S preribosome (inferred); midb ody (inferred); nucleolus (inferred) | | | | Green Monkey | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909597 | Nat10 | N-acetyltransferase 10 | ENCODES a protein that exhibits 18S rRNA cytidine N-acetyltransferase activity (inferred); acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); INVOLVED IN protein acetylation (ortholog); FOUND IN 90S preribosome (inferred); midb ody (inferred); nucleolus (inferred) | | | | Naked Mole-Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155260097 | nat10 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625940892 | Nat10 | N-acetyltransferase 10 | ENCODES a protein that exhibits DNA polymerase binding (ortholog); mRNA N-acetyltransferase activity (ortholog); N-acetyltransferase activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomerase (ortholog); positive regulation of translation (ortholog); protein acetylat ion (ortholog); FOUND IN midbody (ortholog); nucleolus (ortholog); small-subunit processome (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1565991 | Nat14 | N-acetyltransferase 14 | INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 77939430 | 77941950 | Rat | 38 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1601749 | NAT14 | N-acetyltransferase 14 (putative) | Predicted to enable N-acetyltransferase activity. Predicted to be involved in DNA-templated transcription initiation and positive regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 55485188 | 55487566 | Human | 49 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1618012 | Nat14 | N-acetyltransferase 14 | Predicted to enable N-acetyltransferase activity. Predicted to be located in membrane. Orthologous to human NAT14 (N-acetyltransferase 14 (putative)). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 4925250 | 4928005 | Mouse | 48 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8792146 | Nat14 | N-acetyltransferase 14 (putative) | | NW_004955567 | 809832 | 812313 | Chinchilla | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11783358 | NAT14 | N-acetyltransferase 14 (putative) | | 19 | 52529201 | 52531984 | Bonobo | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12427077 | NAT14 | N-acetyltransferase 14 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); N-acetyltransferase activity (inferred); FOUND IN membrane (inferred) | 1 | 102222483 | 102225299 | Dog | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12532265 | Nat14 | N-acetyltransferase 14 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); N-acetyltransferase activity (inferred); FOUND IN membrane (inferred) | NW_004936886 | 711402 | 713557 | Squirrel | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14252518 | NAT14 | N-acetyltransferase 14 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); N-acetyltransferase activity (inferred); FOUND IN membrane (inferred) | | | | Pig | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18539865 | NAT14 | N-acetyltransferase 14 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); N-acetyltransferase activity (inferred); FOUND IN membrane (inferred) | | | | Green Monkey | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18926513 | Nat14 | N-acetyltransferase 14 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); N-acetyltransferase activity (inferred); FOUND IN membrane (inferred) | | | | Naked Mole-Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20865740 | NAT14 | N-acetyltransferase 14 (putative) | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155243878 | nat14 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626141046 | Nat14 | N-acetyltransferase 14 (putative) | | | | | Black Rat | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1601690 | NAT16 | N-acetyltransferase 16 (putative) | Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 101170496 | 101180293 | Human | 22 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8910930 | Nat16 | N-acetyltransferase 16 (putative) | | NW_004955456 | 16114681 | 16118249 | Chinchilla | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11909257 | NAT16 | N-acetyltransferase 16 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); transferase activity (inferred) | 7 | 93310922 | 93320565 | Bonobo | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12387957 | NAT16 | N-acetyltransferase 16 (putative) | | 6 | 8692259 | 8696178 | Dog | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12524682 | Nat16 | N-acetyltransferase 16 (putative) | | NW_004936543 | 1067456 | 1075223 | Squirrel | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18550770 | NAT16 | N-acetyltransferase 16 (putative) | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); transferase activity (inferred) | | | | Green Monkey | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246210 | nat16 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155260177 | nat10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859095 | nat10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863642 | nat10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864485 | nat10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864865 | nat10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626178744 | nat10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245947 | nat14.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244973 | nat14.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626174945 | nat16.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405855918 | nat16.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856182 | nat16.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857451 | nat16.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862618 | nat16.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626182309 | nat16.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626184555 | nat16.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1343133 | NAA15 | N-alpha-acetyltransferase 15, NatA auxiliary subunit | N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes the a uxillary subunit of the N-terminal acetyltransferase A (NatA) complex. [provided by RefSeq, Jan 2017] | 4 | 139301505 | 139391384 | Human | 210 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1346528 | NAA30 | N-alpha-acetyltransferase 30, NatC catalytic subunit | Enables protein-N-terminal amino-acid acetyltransferase activity. Involved in protein stabilization. Located in cytosol and nucleus. Part of NatC complex. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 57390586 | 57415906 | Human | 74 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1558569 | Naa30 | N(alpha)-acetyltransferase 30, NatC catalytic subunit | Predicted to enable protein-N-terminal amino-acid acetyltransferase activity. Predicted to be involved in protein stabilization. Predicted to be located in cytosol and nucleus. Predicted to be part of NatC complex. Orthologous to human NAA30 (N-alpha-acetyltransferase 30, NatC catalytic subunit). [p rovided by Alliance of Genome Resources, Apr 2025] | 14 | 49409703 | 49428346 | Mouse | 79 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1559923 | Naa30 | N(alpha)-acetyltransferase 30, NatC catalytic subunit | ENCODES a protein that exhibits protein-N-terminal amino-acid acetyltransferase activity (ortholog); INVOLVED IN protein stabilization (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); NatC complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; benzo[a]pyrene | 15 | 24935060 | 24954435 | Rat | 78 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12430536 | NAA30 | N-alpha-acetyltransferase 30, NatC catalytic subunit | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); protein N-terminal-methionine acetyltransferase activity (inferred); INVOLVED IN protein stabilization (inferred); FOUND IN cytoplasm (inferred) ; cytosol (inferred); NatC complex (inferred) | 8 | 32939442 | 32959854 | Dog | 17 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1557405 | Naa40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | Predicted to enable histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and protein N-terminal-serine acetyltransferase activity. Acts upstream of or within lipid metabolic process. Predicted to be located in centriolar satellite; cytosol; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human NAA40 (N-alpha-acetyltransferase 40, NatD catalytic subunit). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 7203033 | 7218587 | Mouse | 102 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1565838 | Naa40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | ENCODES a protein that exhibits histone H2A acetyltransferase activity (ortholog); histone H4 acetyltransferase activity (ortholog); protein N-terminal-serine acetyltransferase activity (ortholog); INVOLVED IN lipid metabolic process (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); I NTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 213842686 | 213860079 | Rat | 80 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1602685 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit | Enables histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and protein N-terminal-serine acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within lipid metabolic process. Located in centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 63939002 | 63957319 | Human | 75 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12376758 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); histone H2A acetyltransferase activity (inferred); INVOLVED IN lipid metabolic process (ortholog); FOUND IN cytoplasm (inferred); cytosol (infer red); nucleoplasm (inferred) | 18 | 53054662 | 53077156 | Dog | 21 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1310944 | Naa50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | ENCODES a protein that exhibits histone H4 acetyltransferase activity (ortholog); protein-lysine-acetyltransferase activity (ortholog); protein-N-terminal amino-acid acetyltransferase activity (ortholog); INVOLVED IN establishment of mitotic sister chromatid cohesion (ortholog); mitotic sister chrom atid cohesion, centromeric (ortholog); N-terminal protein amino acid acetylation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); NatA complex (ortholog); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; alpha-Zearalanol | 11 | 70044281 | 70066754 | Rat | 116 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1322131 | NAA50 | N-alpha-acetyltransferase 50, NatE catalytic subunit | Enables histone H4 acetyltransferase activity and protein-N-terminal amino-acid acetyltransferase activity. Involved in N-terminal protein amino acid acetylation; establishment of mitotic sister chromatid cohesion; and mitotic sister chromatid cohesion, centromeric. Located in cytosol and nucleolus. Part of NatA complex. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 113716458 | 113746249 | Human | 112 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1322132 | Naa50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | Predicted to enable histone H4 acetyltransferase activity and protein-N-terminal amino-acid acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation; establishment of mitotic sister chromatid cohesion; and mitotic sister chromatid cohesion, centromeric. Predi cted to be located in cytosol and nucleolus. Predicted to be part of NatA complex. Is expressed in several structures, including alimentary system; integumental system; nose; respiratory system; and telencephalon. Orthologous to human NAA50 (N-alpha-acetyltransferase 50, NatE catalytic subunit). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 43960154 | 43983825 | Mouse | 128 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1308915 | Naa60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit | ENCODES a protein that exhibits histone H4 acetyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-N-terminal amino-acid acetyltransferase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); chromosome segregation (ortholog); N-terminal pep tidyl-methionine acetylation (ortholog); ASSOCIATED WITH Idiopathic Basal Ganglia Calcification 1 (ortholog); Idiopathic Basal Ganglia Calcification 9 (ortholog); FOUND IN Golgi membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 10 | 12129026 | 12149053 | Rat | 85 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1318957 | Naa60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit | Predicted to enable histone H4 acetyltransferase activity; protein homodimerization activity; and protein-N-terminal amino-acid acetyltransferase activity. Predicted to be involved in several processes, including N-terminal peptidyl-methionine acetylation; chromosome segregation; and nucleosome asse mbly. Predicted to be active in Golgi membrane. Orthologous to human NAA60 (N-alpha-acetyltransferase 60, NatF catalytic subunit). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 3690365 | 3722645 | Mouse | 92 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1605347 | NAA60 | N-alpha-acetyltransferase 60, NatF catalytic subunit | This gene encodes an enzyme that localizes to the Golgi apparatus, where it transfers an acetyl group to the N-terminus of free proteins. This enzyme acts on histones, and its activity is important for chromatin assembly and chromosome integrity. Alternative splicing and the use of alternative promo ters results in multiple transcript variants. The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting; transcript variants originating from this position are expressed from the maternal allele. [provided by RefSeq, Nov 2015] | 16 | 3443611 | 3486963 | Human | 162 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 12118189 | NAA60 | N-alpha-acetyltransferase 60, NatF catalytic subunit | ENCODES a protein that exhibits histone H4 acetyltransferase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cell population proliferation (ortholog); N-terminal peptidyl-methionine acetylation (ortholog); N-terminal protein amino acid acetylation (ortholog); ASSOCIATE D WITH Idiopathic Basal Ganglia Calcification 1 (ortholog); Idiopathic Basal Ganglia Calcification 9 (ortholog); FOUND IN Golgi membrane (inferred) | 6 | 37759233 | 37784224 | Dog | 25 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 732527 | NAT2 | N-acetyltransferase 2 | This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polym orphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019] | 8 | 18386301 | 18401218 | Human | 302 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 732528 | Nat2 | N-acetyltransferase 2 (arylamine N-acetyltransferase) | Enables arylamine N-acetyltransferase activity. Predicted to be located in cytoplasm. Is expressed in several structures, including adrenal gland; female reproductive system; respiratory system; spleen; and sympathetic ganglion. Human ortholog(s) of this gene implicated in several diseases, includin g autoimmune disease (multiple); carcinoma (multiple); contact dermatitis (multiple); leukemia (multiple); and lung disease (multiple). Orthologous to several human genes including NAT1 (N-acetyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 67947527 | 67955296 | Mouse | 311 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1316848 | Nat3 | N-acetyltransferase 3 | Enables L-amino acid transmembrane transporter activity. Acts upstream of or within L-amino acid transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); contact dermatitis (multiple); leukemi a (multiple); and lung disease (multiple). Orthologous to human NAT1 (N-acetyltransferase 1) and NAT2 (N-acetyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 67976506 | 68001279 | Mouse | 17 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308854 | Thumpd1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 1,2-dimethylhydrazine; 2,4-dinitrotoluene | 1 | 183510242 | 183516282 | Rat | 73 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1318865 | THUMPD1 | THUMP domain 1 NAT10 acetyltransferase adaptor | Enables RNA binding activity. Predicted to be involved in tRNA modification. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 20733664 | 20741818 | Human | 98 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 8753248 | Thumpd1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog) | NW_004955493 | 32326 | 40283 | Chinchilla | 2 | name | gene, protein-coding, MODEL [RefSeq] |
| 11671200 | THUMPD1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog) | 16 | 17666536 | 17677158 | Bonobo | 8 | name | gene, protein-coding, MODEL [RefSeq] |
| 12554958 | Thumpd1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog) | NW_004936501 | 6050866 | 6058171 | Squirrel | 8 | name | gene, protein-coding, MODEL [RefSeq] |
| 18389278 | THUMPD1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog) | | | | Green Monkey | 8 | name | gene, protein-coding, MODEL [RefSeq] |
| 18919765 | Thumpd1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog) | | | | Naked Mole-Rat | 8 | name | gene, protein-coding, MODEL [RefSeq] |
| 626098455 | Thumpd1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog) | | | | Black Rat | 2 | name | gene, protein-coding, MODEL [RefSeq] |
| 16552013 | NAA50P2 | NAA50 pseudogene 2 | | | | | Human | | old_gene_name | gene, unprocessed_pseudogene |
