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Gene: Nat2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)) Mus musculus
Symbol: Nat2
Name: N-acetyltransferase 2 (arylamine N-acetyltransferase)
Description: Exhibits arylamine N-acetyltransferase activity. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); dermatitis (multiple); leukemia (multiple); lung disease (multiple); and rheumatic disease (multiple). Is expressed in several structures, including adrenal gland; female reproductive system; respiratory system; spleen; and sympathetic ganglion. Orthologous to several human genes including NAT1 (N-acetyltransferase 1); PARTICIPATES IN caffeine pharmacokinetics pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 4-aminobenzoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: arylamide acetylase 2; arylamine N-acetyltransferase 2; AV377607; N-acetyl transferase 2; N-acetyltransferase type 2; NAT-2
Homo sapiens (human) : NAT2 (N-acetyltransferase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nat2 (N-acetyltransferase 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NAT2 (N-acetyltransferase 2)
Chlorocebus sabaeus (green monkey) : NAT2 (N-acetyltransferase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: Loci in other organisms that are functionally homologous to this one are validly referred to as both NAT1 and NAT2; i.e., the functional homologs of NAT1 include mouse and rat Nat2, while the functional homologs of human NAT2 include mouse and rat Nat1. Name:sequence associations are consistent with current use in the field. [13 Feb 2013]
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl867,494,858 - 67,502,584 (+)Ensembl
GRCm38867,494,875 - 67,502,644 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37870,018,774 - 70,026,479 (+)NCBIGRCm37mm9NCBIm37
MGSCv36870,423,937 - 70,431,559 (+)NCBImm8
Celera870,048,329 - 70,056,034 (+)NCBICelera
Cytogenetic Map8 B3.2NCBI
cM Map833.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nat2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732528
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.