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Gene: Nat2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)) Mus musculus
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Symbol: Nat2
Name: N-acetyltransferase 2 (arylamine N-acetyltransferase)
Description: Exhibits arylamine N-acetyltransferase activity. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); dermatitis (multiple); leukemia (multiple); lung disease (multiple); and rheumatic disease (multiple). Is expressed in several structures, including adrenal gland; female reproductive system; respiratory system; spleen; and sympathetic ganglion. Orthologous to several human genes including NAT1 (N-acetyltransferase 1); PARTICIPATES IN caffeine pharmacokinetics pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 4-aminobenzoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: arylamide acetylase 2; arylamine N-acetyltransferase 2; AV377607; N-acetyl transferase 2; N-acetyltransferase type 2; NAT-2
Orthologs:
Homo sapiens (human) : NAT2 (N-acetyltransferase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nat2 (N-acetyltransferase 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NAT2 (N-acetyltransferase 2)
Chlorocebus sabaeus (green monkey) : NAT2 (N-acetyltransferase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: Loci in other organisms that are functionally homologous to this one are validly referred to as both NAT1 and NAT2; i.e., the functional homologs of NAT1 include mouse and rat Nat2, while the functional homologs of human NAT2 include mouse and rat Nat1. Name:sequence associations are consistent with current use in the field. [13 Feb 2013]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl867,494,858 - 67,502,584 (+)Ensembl
GRCm38867,494,875 - 67,502,644 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37870,018,774 - 70,026,479 (+)NCBIGRCm37mm9NCBIm37
MGSCv36870,423,937 - 70,431,559 (+)NCBImm8
Celera870,048,329 - 70,056,034 (+)NCBICelera
Cytogenetic Map8 B3.2NCBI
cM Map833.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732528
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.