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57 records found for search term Il10
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2886Il10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding; cytokine activity (ortholog); protein dimerization activity (ortholog); INVOLVED IN cellular response to estradiol stimulus; immune response; liver regeneration; PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-4 signaling134502492145029586Rat1872symbol , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
10785Il10interleukin 10This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress a1130947459130952707Mouse2122array_id_rg_u34b_affymetrix , symbol , array_id_affy_mg_u74c_ensembl , PhenoGen , array_id_affy_mu11ksuba_ensembl , array_id_affy_mg_u74b_ensembl , array_id_affy_mg_u74av2_ensembl , array_id_rg_u34c_affymetrix , array_id_affy_mg_u74a_ensembl , array_id_rg_u34a_affymetrix , array_id_affy_mg_u74cv2_engene, protein-coding, REVIEWED [RefSeq]
735591IL10interleukin 10The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrop1206767602206772494Human2061symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
8705394Il10interleukin 10ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-10 receptor binding (ortholog); protein dimerization activity (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradioNW_0049554064230778942312255Chinchilla500symbolgene, protein-coding, MODEL [RefSeq]
11872917IL10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradiol stimulus (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway;1182369234182374207Bonobo505symbolgene, protein-coding, MODEL [RefSeq]
12383470IL10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradiol stimulus (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway;759332855937057Dog525symbolgene, protein-coding, PROVISIONAL [RefSeq]
12567926Il10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradiol stimulus (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway;NW_00493655758348745838502Squirrel504symbolgene, protein-coding, MODEL [RefSeq]
14209127IL10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN cellular response to antibiotic; cellular response to virus; branching involved in labyrinthine layer morphogenesis (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-4 signaling pathway; APig532symbolgene, protein-coding, PROVISIONAL [RefSeq]
18418932IL10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradiol stimulus (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway;Green Monkey504symbolgene, protein-coding, MODEL [RefSeq]
18901054Il10interleukin 10ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradiol stimulus (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway;Naked Mole-Rat504symbolgene, protein-coding, MODEL [RefSeq]
155249630il10Tropical Clawed Frogsymbolgene, null
626165333Il10interleukin 10ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-10 receptor binding (ortholog); protein dimerization activity (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); cellular response to estradioBlack Rat499symbolgene, protein-coding, MODEL [RefSeq]
155254761il10.LAfrican Clawed Frogsymbolgene, null
155246077il10.SAfrican Clawed Frogsymbolgene, null
620138Il10rainterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding; interleukin-10 receptor activity; INVOLVED IN regulation of synapse organization; response to lipopolysaccharide; interleukin-10-mediated signaling pathway (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; cytokine mediated signalin85445975454474786Rat154symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
731000IL10RAinterleukin 10 receptor subunit alphaThe protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to pro11117986394118003037Human206symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
731001Il10rainterleukin 10 receptor, alphaPredicted to enable interleukin-10 binding activity and interleukin-10 receptor activity. Predicted to be involved in several processes, including interleukin-10-mediated signaling pathway; intestinal epithelial structure maintenance; and ubiquitin-dependent endocytosis. Predicted to be located in c94516513545180447Mouse198symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8870193Il10rainterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); intestinal epithelial structure maintenance (ortholog); negative regulation of autophagy (ortholog); PARTICIPATES IN InterNW_0049554121918253619197083Chinchilla34symbolgene, protein-coding, MODEL [RefSeq]
11682135IL10RAinterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH COVID-19 (ortholog);11112820445112835603Bonobo39symbolgene, protein-coding, MODEL [RefSeq]
12381536IL10RAinterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH COVID-19 (ortholog);51567577515688935Dog38symbolgene, protein-coding, MODEL [RefSeq]
12678253Il10rainterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH COVID-19 (ortholog);NW_00493654230994843113159Squirrel39symbolgene, protein-coding, MODEL [RefSeq]
13972708IL10RAinterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH COVID-19 (ortholog);Pig38symbolgene, protein-coding, MODEL [RefSeq]
18487568IL10RAinterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH COVID-19 (ortholog);Green Monkey39symbolgene, protein-coding, MODEL [RefSeq]
18913398Il10rainterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH COVID-19 (ortholog);Naked Mole-Rat38symbolgene, protein-coding, MODEL [RefSeq]
288083405il10raTropical Clawed Frogsymbolgene, null
625961627Il10rainterleukin 10 receptor subunit alphaENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); intestinal epithelial structure maintenance (ortholog); negative regulation of autophagy (ortholog); PARTICIPATES IN InterBlack Rat34symbolgene, protein-coding, MODEL [RefSeq]
1345772IL10RBinterleukin 10 receptor subunit betaThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10213326636733310182Human154symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1556884Il10rbinterleukin 10 receptor, betaEnables interleukin-10 receptor activity. Predicted to be involved in interleukin-10-mediated signaling pathway; positive regulation of cellular respiration; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in membrane. Predicted to be active in plasma memb169120316691222718Mouse153symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1560373Il10rbinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); positive regulation of cellular respiration (ortholog); positive regulation of receptor signaling pathway via JAK-STAT (ortho114413247144154062Rat130symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
9030080Il10rbinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); positive regulation of cellular respiration (ortholog); positive regulation of receptor signaling pathway via JAK-STAT (orthoNW_0049554073264109732659360Chinchilla20symbolgene, protein-coding, MODEL [RefSeq]
11786188IL10RBinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (inferred); cytokine receptor activity (inferred); interleukin-10 receptor activity (inferred); INVOLVED IN cytokine-mediated signaling pathway (inferred); defense response to virus (inferred); interleukin-10-mediated signaling pathway (inferred); 211962880819668268Bonobo25symbolgene, protein-coding, MODEL [RefSeq]
12253882IL10RBinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (inferred); signaling receptor activity (inferred); INVOLVED IN blood coagulation (inferred); cytokine-mediated signaling pathway (inferred); defense response to virus (inferred); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH br312879154128815163Dog29symbolgene, protein-coding, MODEL [RefSeq]
12551263Il10rbinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (inferred); cytokine receptor activity (inferred); interleukin-10 receptor activity (inferred); INVOLVED IN cytokine-mediated signaling pathway (inferred); defense response to virus (inferred); interleukin-10-mediated signaling pathway (inferred); NW_00493650090330779057465Squirrel25symbolgene, protein-coding, MODEL [RefSeq]
14133381IL10RBinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (inferred); signaling receptor activity (inferred); INVOLVED IN cytokine-mediated signaling pathway (inferred); defense response to virus (inferred); interleukin-10-mediated signaling pathway (inferred); PARTICIPATES IN Interleukin-10 signaling patPig24symbolgene, protein-coding, PROVISIONAL [RefSeq]
18499833IL10RBinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (inferred); cytokine receptor activity (inferred); interleukin-10 receptor activity (inferred); INVOLVED IN cytokine-mediated signaling pathway (inferred); defense response to virus (inferred); interleukin-10-mediated signaling pathway (inferred); Green Monkey25symbolgene, protein-coding, MODEL [RefSeq]
18928850Il10rbinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); positive regulation of cellular respiration (ortholog); positive regulation of receptor signaling pathway via JAK-STAT (ortholog); PARTICIPATES IN Interleukin-10 signalinNaked Mole-Rat27symbolgene, protein-coding, MODEL [RefSeq]
20866602IL10RBinterleukin 10 receptor subunit betaGreen Monkeysymbolgene, protein-coding
284471979il10rbTropical Clawed Frogsymbolgene, null
626100223Il10rbinterleukin 10 receptor subunit betaENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); positive regulation of cellular respiration (ortholog); positive regulation of receptor signaling pathway via JAK-STAT (orthoBlack Rat20symbolgene, protein-coding, MODEL [RefSeq]
286292928il10ra.LAfrican Clawed Frogsymbolgene, null
287717554il10ra.SAfrican Clawed Frogsymbolgene, null
284470981il10rb.LAfrican Clawed Frogsymbolgene, null
286578015il10rb.SAfrican Clawed Frogsymbolgene, null
7252141IL10RB-DTIL10RB divergent transcriptINTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; antirheumatic drug; cisplatin213326563233266260Human6symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbolgene, ncrna, VALIDATED [RefSeq]
155773416IFNAR2-IL10RBIFNAR2-IL10RB readthroughThis locus represents naturally occurring readthrough transcription between the neighboring IFNAR2 (interferon alpha and beta receptor subunit 2) and IL10RB (interleukin 10 receptor subunit beta) genes on chromosome 21. The readthrough transcript encodes a prote213322993833297221Human7symbol , old_gene_name , COSMIC , name , description , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1353403IL20interleukin 20The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this c1206863565206869223Human70description , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1605405IL24interleukin 24This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this g1206897443206904139Human250description , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1315107IL19interleukin 19The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activato1206770773206842981Human82descriptiongene, protein-coding, REVIEWED [RefSeq]
1344987IL22interleukin 22This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a rol126824824268253604Human136descriptiongene, protein-coding, REVIEWED [RefSeq]
1352751IL22RA1interleukin 22 receptor subunit alpha 1The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a12411977124143140Human98descriptiongene, protein-coding, REVIEWED [RefSeq]
1346180IL26interleukin 26This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contrib126820134968225810Human40descriptiongene, protein-coding, REVIEWED [RefSeq]
1352815SOCS2suppressor of cytokine signaling 2This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins 129356996993626236Human320descriptiongene, protein-coding, REVIEWED [RefSeq]
730833SOCS3suppressor of cytokine signaling 3This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10177835677878360925Human491descriptiongene, protein-coding, REVIEWED [RefSeq]
1347142IFNL1interferon lambda 1This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines e193929640739298673Human67descriptiongene, protein-coding, REVIEWED [RefSeq]
1351993IFNL2interferon lambda 2This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines enc193926839639270188Human33descriptiongene, protein-coding, VALIDATED [RefSeq]
1348657IFNL3interferon lambda 3This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines enc193924345539245250Human69descriptiongene, protein-coding, REVIEWED [RefSeq]
1603554IFNLR1interferon lambda receptor 1The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including12415416824187289Human84descriptiongene, protein-coding, REVIEWED [RefSeq]