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42 records found for search term Gcg
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2668GcgglucagonENCODES a protein that exhibits glucagon receptor binding; hormone activity; gastric inhibitory polypeptide receptor binding (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of appetite; response to L-arginine; PARTICIPATES IN for36752248967531533Rat271symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
10626GcgglucagonThis gene encodes glucagon, a pancreatic hormone that counteracts the action of insulin in the bloodstream. The encoded protein is processed to generate glucagon and two other glucagon-like peptides, GLP1 and GLP2. Glucagon stimulates gluconeogenesis, glycogenolysis and lipolysis. GLP1 induces secre26230487462313997Mouse269symbol , PhenoGengene, protein-coding, REVIEWED [RefSeq]
68970GCGglucagonThe protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a speci2162142882162152247Human261symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8840939GcgglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN positive regulation of adenylate cyclase activity; adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortNW_0049554491170815211716429Chinchilla71symbolgene, protein-coding, MODEL [RefSeq]
11754449GCGglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); intracellular glucose homeostasis (ortholog2B4943637949446559Bonobo76symbolgene, protein-coding, MODEL [RefSeq]
12079627GCGglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); glucose homeostasis (ortholog); intracellul3675446377554171Dog79symbolgene, protein-coding, PROVISIONAL [RefSeq]
12716296GcgglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); intracellular glucose homeostasis (orthologNW_0049364691690665816916045Squirrel76symbolgene, protein-coding, MODEL [RefSeq]
13851160GCGglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN positive regulation of bicellular tight junction assembly; positive regulation of ERK1 and ERK2 cascade; adenylate cyclase-modulaPig82symbolgene, protein-coding, PROVISIONAL [RefSeq]
18555556GCGglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); intracellular glucose homeostasis (orthologGreen Monkey76symbolgene, protein-coding, MODEL [RefSeq]
18916317GcgglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupNaked Mole-Rat75symbolgene, protein-coding, MODEL [RefSeq]
20867169GCGglucagonGreen Monkeysymbolgene, protein-coding
155233872gcgTropical Clawed Frogsymbolgene, null
626085216GcgglucagonENCODES a protein that exhibits gastric inhibitory polypeptide receptor binding (ortholog); glucagon receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupBlack Rat70symbolgene, protein-coding, MODEL [RefSeq]
155249711gcg.LAfrican Clawed Frogsymbolgene, null
626187572gcg.SAfrican Clawed Frogsymbolgene, null
15036840Trnar-gcgtransfer RNA arginine (anticodon GCG)This record serves to anchor the annotations of this class of tRNAs at multiple locations on the chinchilla, long-tailed genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMeChinchillasymbol , namegene, trna
625840747Trnar-gcgtransfer RNA arginine (anticodon GCG)This record represents a tRNA model predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).Black Ratsymbol , namegene, trna, MODEL [RefSeq]
626152484Trnar-gcgtransfer RNA arginine (anticodon GCG)This record represents a tRNA model predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).Black Ratsymbol , namegene, trna, MODEL [RefSeq]
1307153Chac1ChaC glutathione-specific gamma-glutamylcyclotransferase 1ENCODES a protein that exhibits glutathione specific gamma-glutamylcyclotransferase activity (ortholog); Notch binding (ortholog); INVOLVED IN intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ortholog); negative regulation of Notch signaling pathway (ortholog); nega3126796131126799352Rat311old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1316176Chac1ChaC, cation transport regulator 1Enables Notch binding activity. Involved in neurogenesis. Acts upstream of or within response to caloric restriction. Located in trans-Golgi network. Is expressed in several structures, including bone; brain; gonad; hemolymphoid system gland; and neural ectoderm. Orthologous to human CHAC1 (ChaC glu2119181723119184807Mouse308old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1604291CHAC1ChaC glutathione specific gamma-glutamylcyclotransferase 1This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in th154095347140956512Human305old_gene_namegene, protein-coding, REVIEWED [RefSeq]
1309120Chac2ChaC glutathione specific gamma-glutamylcyclotransferase 2ENCODES a protein that exhibits glutathione specific gamma-glutamylcyclotransferase activity (ortholog); INVOLVED IN glutathione catabolic process (inferred); FOUND IN cytosol (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide14108921669108929215Rat124old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1319283Chac2ChaC, cation transport regulator 2Predicted to enable glutathione specific gamma-glutamylcyclotransferase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human CHAC2 (ChaC glutathione specific gamma-glutamylcyclotransferase 2113092670730936365Mouse122old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1606619CHAC2ChaC glutathione specific gamma-glutamylcyclotransferase 2The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis. [pro25376778353775196Human124old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
14371077GCG1Yeastsymbolgene, null
2669Gcgrglucagon receptorENCODES a protein that exhibits glucagon receptor activity; peptide hormone binding; INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; exocytosis; PARTICIPATES IN G protein mediated signal10106306803106314970Rat182symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
69010GCGRglucagon receptorThe protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]178180415081814008Human201symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1332263Gcgrglucagon receptorEnables glucagon receptor activity. Involved in several processes, including cellular response to glucagon stimulus; glucose homeostasis; and regulation of glycogen metabolic process. Acts upstream of or within cellular response to starvation and positive regulation of gene expression. Is active in 11120420011120429815Mouse270symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9027570Gcgrglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular NW_00495550613404101348028Chinchilla32symbolgene, protein-coding, MODEL [RefSeq]
11846774GCGRglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular 177620502376220171Bonobo44symbolgene, protein-coding, MODEL [RefSeq]
12435104GCGRglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular 9455744463070Dog38symbolgene, protein-coding, MODEL [RefSeq]
12447688Gcgrglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular NW_00493659453477895351852Squirrel43symbolgene, protein-coding, MODEL [RefSeq]
14186528GCGRglucagon receptorENCODES a protein that exhibits glucagon receptor activity; peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular response toPig45symbolgene, protein-coding, MODEL [RefSeq]
18471836GCGRglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular Green Monkey43symbolgene, protein-coding, MODEL [RefSeq]
18929383Gcgrglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular Naked Mole-Rat44symbolgene, protein-coding, MODEL [RefSeq]
155231224gcgrTropical Clawed Frogsymbolgene, null
625882070Gcgrglucagon receptorENCODES a protein that exhibits glucagon receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cellular Black Rat32symbolgene, protein-coding, MODEL [RefSeq]
155232347gcgr.LAfrican Clawed Frogsymbolgene, null
737005GPX1glutathione peroxidase 1The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for gro34935717649358353Human1328descriptiongene, protein-coding, REVIEWED [RefSeq]
1345820PABPN1poly(A) binding protein nuclear 1This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-st142332145723326163Human169descriptiongene, protein-coding, REVIEWED [RefSeq]
151347606Ddah1em1Ywxudimethylarginine dimethylaminohydrolase 1; CRISPR/Cas9 induced mutant 1, YwxuASSOCIATED WITH increased aorta wall thickness; increased heart right ventricle weight; increased right ventricle systolic pressure; ASSOCIATED WITH Pulmonary Arterial HypertensionRat7descriptiongene, allele
2546Egr4early growth response 4ENCODES a protein that exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to growth factor stimulus; pos4119605358119607817Rat125old_gene_namegene, protein-coding, VALIDATED [RefSeq]