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Strain: F344

Symbol: F344
Strain: F344
Full Name: Fischer
RGD ID: 60994
Citation ID: RRID:RGD_60994
Ontology ID: RS:0000215
Type: inbred
Available Source: NIH Autoimmune Rat Model Repository and Development Center
Origination: NIH Autoimmune Rat Model Repository and Development Center
Description: Curtiss and Dunning 1920 at Columbia University Institute for Cancer Research,To Heston 1949 (Billingham and Silvers 1959). To National Institutes of Health in 1951 (Hansen et al 1982). Subsequent sublines from Dunning or NIH.
Coat Color: Albino.
Inbred Generations: F155
Last Known Status: Unknown

Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
brain ventricle morphology trait  EXP 68693 RGD 
femur mineral mass  EXP 1553896 RGD 
heart left ventricle mass  EXP 1578627 RGD 
lumbar vertebra area  EXP 1553896 RGD 
lumbar vertebra mineral mass  EXP 1553896 RGD 


References - curated
# Reference Title Reference Citation
1. Fine mapping of Lvm1: a quantitative trait locus controlling heart size independently of blood pressure. Di Nicolantonio R, etal., Pulm Pharmacol Ther. 2006;19(1):70-3. Epub 2005 Apr 25.
2. Genome-wide linkage analysis of inherited hydrocephalus in the H-Tx rat. Jones HC, etal., Mamm Genome 2001 Jan;12(1):22-6.
3. Genome screen for bone mineral density phenotypes in Fisher 344 and Lewis rat strains. Koller DL, etal., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14.
4. A new obesity-prone, glucose-intolerant rat strain (F.DIO). Levin BE, etal., Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R1184-91. Epub 2003 Jul 10.
5. F-DIO obesity-prone rat is insulin resistant before obesity onset. Levin BE, etal., Am J Physiol Regul Integr Comp Physiol. 2005 Sep;289(3):R704-11. doi: 10.1152/ajpregu.00216.2005. Epub 2005 May 5.
6. Gain of function mutation in the mineralocorticoid receptor of the Brown Norway rat. Marissal-Arvy N, etal., J Biol Chem 2004 Sep 17;279(38):39232-9. Epub 2004 Jul 12.


Strain QTL Data
Symbol Name Trait
Bmd1 Bone mineral density QTL 1 femur mineral mass   (VT:0010011)    
Bmd2 Bone mineral density QTL 2 lumbar vertebra area   (VT:0010570)    
Bmd3 Bone mineral density QTL 3 femur mineral mass   (VT:0010011)    
Bmd4 Bone mineral density QTL 4 lumbar vertebra mineral mass   (VT:0010511)    
Bmd5 Bone mineral density QTL 5 lumbar vertebra mineral mass   (VT:0010511)    
Bvd6 Brain ventricular dilatation QTL 6 brain ventricle morphology trait   (VT:0000822)    
Cm49 Cardiac mass QTL 49 heart left ventricle mass   (VT:0007031)    

Additional Information