Strain Report - Rat Genome Database

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Strain: F344/Crli

Symbol: F344/Crli
Strain: F344
Substrain: Crli
RGD ID: 737690
Citation ID: RRID:RGD_737690
Ontology ID: RS:0000307
Type: inbred
Source: Charles River, Calco, Italy
Origin: These animals were from Charles River Italia, Calco, LC, Italy
Last Known Status: Unknown

Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344/Crli  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
liver integrity trait  EXP 629566 RGD 

Disease Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease. Calvisi DF, etal., Int J Cancer. 2009 Jun 16.
2. Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis. De Miglio MR, etal., Cancer Res 2002 Aug 1;62(15):4459-63.
3. Mapping a sex hormone-sensitive gene determining female resistance to liver carcinogenesis in a congenic F344.BN-Hcs4 rat. De Miglio MR, etal., Cancer Res. 2006 Nov 1;66(21):10384-90.
4. Phenotypic reversion of rat neoplastic liver nodules is under genetic control. De Miglio MR, etal., Int J Cancer 2003 May 20;105(1):70-5.
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Strain QTL Data
Symbol Name Trait
Hcar10 Hepatocarcinoma resistance QTL 10 liver integrity trait   (VT:0010547)    
Hcar11 Hepatocarcinoma resistance QTL 11 liver integrity trait   (VT:0010547)    
Hcar12 Hepatocarcinoma resistance QTL 12 liver integrity trait   (VT:0010547)    
Hcar9 Hepatocarcinoma resistance QTL 9 liver integrity trait   (VT:0010547)    
Hcas3 Hepatocarcinoma susceptibility QTL 3 liver integrity trait   (VT:0010547)    
Hcas4 Hepatocarcinoma susceptibility QTL 4 liver integrity trait   (VT:0010547)    

Additional Information