Strain Report - Rat Genome Database

Name: F344/Stm
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: F344/Stm
Symbol:	F344/Stm
Strain:	F344
Substrain:	Stm
RGD ID:	1302686
Citation ID:	RRID:RGD_1302686
Ontology ID:	RS:0000428
Also known as:	NBRP Rat No: 0140; MDC-01-73
Type:	inbred
Source:	National BioResource Project for the Rat in Japan
Origin:	Derived from F344/DuCrlj rats that were purchased from Charles River Kanagawa, Japan. These are maintained by brother and sister mating.
Inbred Generations:	F23
Last Known Status:	Live Animals; Cryopreserved Embryo; Cryopreserved Sperm
Research Usage	Diabetes Obesity; Cancer

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

T-Cell Lymphoma (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased T cell derived lymphoma incidence (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

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Clinical Measurement

heart rate

systolic blood pressure

body weight

body temperature

red blood cell count

blood hemoglobin level

white blood cell count

platelet count

hematocrit

mean corpuscular volume

plasma glucose level

plasma aspartate aminotransferase activity level

plasma alanine aminotransferase activity level

plasma alkaline phosphatase activity level

plasma total protein level

plasma albumin level

plasma phosphate level

plasma chloride level

plasma sodium level

plasma potassium level

heart wet weight

heart weight to body weight ratio

both kidneys wet weight

lung wet weight

urine potassium level

urine sodium level

brain weight to body weight ratio

both kidneys wet weight as percentage of body weight

liver weight as percentage of body weight

spleen weight to body weight ratio

brain wet weight

lung weight to body weight ratio

liver wet weight

both adrenal glands wet weight

spleen wet weight

both testes wet weight

activated partial thromboplastin time

prothrombin time

timed urine volume

mean corpuscular hemoglobin

mean corpuscular hemoglobin concentration

blood basophil count to total leukocyte count ratio

blood eosinophil count to total leukocyte count ratio

blood lymphocyte count to total leukocyte count ratio

blood monocyte count to total leukocyte count ratio

total plasma calcium level

urine chloride level

plasma creatinine level

plasma triglyceride level

plasma total cholesterol level

plasma urea nitrogen level

both adrenal glands weight to body weight ratio

plasma high density lipoprotein cholesterol level

plasma low density lipoprotein cholesterol level

both testes wet weight to body weight ratio

urine sodium excretion rate to body weight ratio

timed urine volume to body weight ratio

urine chloride excretion rate to body weight ratio

urine potassium excretion rate to body weight ratio

plasma total bilirubin level

blood segmented neutrophil count to total leukocyte count ratio

blood band neutrophil count to total leukocyte count ratio

non-specified leukocyte count to total leukocyte count ratio

plasma albumin to plasma total protein ratio

References

References - curated


1.	Hashimoto R, etal., Exp Anim. 2013;62(3):181-7.
2.	Lu LM, etal., Br J Cancer 1999 May;80(5-6):855-61.
3.	Mashimo T, etal., BMC Genet. 2006 Apr 4;7:19.
4.	Personal Communication with NBRP
5.	RGD Automated Pipelines
6.	Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
7.	Shisa H, etal., Mamm Genome 1997 May;8(5):324-7.

Region

Damaging Variants

	Number of Damaging Variants
Sample	Rnor_6.0	Rnor_5.0	RGSC_v3.4
F344/Stm (KyushuU)		1181
F344/Stm (2019)	2704
F344/Stm (2019)

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_other	A BAC library for this strain is available from the RIKEN BioResource Center.	2292911
strain_reproduction	Good breeding performance.	628402

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-05-09	F344/Stm		F344/Stm		Name updated	68913	APPROVED
2012-05-09	F344/Stm		F344/Stm		Name updated	68913	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: F344/Stm

Related Phenotype Data for Term "F344/Stm" (RS:0000428)