Hrc (histidine rich calcium binding protein) - Rat Genome Database

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Gene: Hrc (histidine rich calcium binding protein) Rattus norvegicus
Analyze
Symbol: Hrc
Name: histidine rich calcium binding protein
RGD ID: 727864
Description: Predicted to enable ATPase binding activity; calcium ion binding activity; and transmembrane transporter binding activity. Involved in negative regulation of calcium ion import into sarcoplasmic reticulum and negative regulation of cytosolic calcium ion concentration. Predicted to be located in several cellular components, including Z disc; mitochondrion; and sarcoplasmic reticulum membrane. Orthologous to human HRC (histidine rich calcium binding protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: sarcoplasmic reticulum histidine-rich calcium-binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,949,750 - 104,953,475 (+)NCBIGRCr8
mRatBN7.2195,813,262 - 95,816,987 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,813,253 - 95,816,984 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,198,707 - 101,202,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,671,382 - 109,675,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,961,782 - 102,965,504 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,324,788 - 101,328,391 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,324,652 - 101,328,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,388,311 - 102,391,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,805,143 - 95,808,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,883,253 - 95,886,857 (+)NCBI
Celera190,069,730 - 90,073,333 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
HrcRatCardiac Fibrosis severityISOHrc (Mus musculus)9685495associated with Heart FailureRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
HrcRatBrugada syndrome  ISOHRC (Homo sapiens)8554872ClinVar Annotator: match by term: Sudden Unexplained Nocturnal Death Syndrome (SUNDS)ClinVarPMID:20562447 more ...
HrcRatdevelopmental and epileptic encephalopathy 12  ISOHRC (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 12ClinVarPMID:28492532
HrcRatprogressive familial heart block  ISOHRC (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary bundle branch system defectClinVarPMID:20562447 more ...
HrcRatProgressive Familial Heart Block Type I  ISOHRC (Homo sapiens)8554872ClinVar Annotator: match by term: Heart block progressive familial type 1ClinVarPMID:20562447 more ...
HrcRatprogressive familial heart block type IA  ISOHRC (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary bundle branch system defectClinVarPMID:20562447 more ...
HrcRatprogressive familial heart block type IB  ISOHRC (Homo sapiens)8554872ClinVar more ...ClinVarPMID:20562447 more ...
HrcRatSudden Unexpected Nocturnal Death Syndrome  ISOHRC (Homo sapiens)8554872ClinVar Annotator: match by term: Sudden unexpected nocturnal death syndromeClinVarPMID:20562447 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
HrcRatBody Weight  ISOHRC (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17030629
HrcRatCardiomegaly  ISOHRC (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17030629

1 to 20 of 66 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
HrcRat1,2-dimethylhydrazine decreases expressionISOHrc (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of HRC mRNACTDPMID:22206623
HrcRat17beta-estradiol decreases expressionISOHrc (Mus musculus)6480464Estradiol results in decreased expression of HRC mRNACTDPMID:19484750
HrcRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of HRC mRNACTDPMID:32145629
HrcRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of HRC mRNACTDPMID:32109520
HrcRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of HRC mRNACTDPMID:34747641
HrcRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
HrcRat4,4'-sulfonyldiphenol increases expressionISOHrc (Mus musculus)6480464bisphenol S results in increased expression of HRC mRNACTDPMID:30951980
HrcRat4,4'-sulfonyldiphenol decreases methylationISOHrc (Mus musculus)6480464bisphenol S results in decreased methylation of HRC exonCTDPMID:33297965
HrcRat5-aza-2'-deoxycytidine affects expressionISOHRC (Homo sapiens)6480464Decitabine affects the expression of HRC mRNACTDPMID:23300844
HrcRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of HRC mRNACTDPMID:24780913
HrcRatalpha-Zearalanol decreases expressionEXP 6480464Zeranol results in decreased expression of HRC mRNACTDPMID:35163327
HrcRatalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of HRC mRNACTDPMID:35163327
HrcRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of HRC mRNACTDPMID:16483693
HrcRatamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of HRC mRNACTDPMID:30779732
HrcRatatrazine decreases expressionEXP 6480464Atrazine results in decreased expression of HRC mRNACTDPMID:36841081
HrcRatbenzo[a]pyrene decreases expressionISOHrc (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of HRC mRNACTDPMID:22228805
HrcRatbenzo[a]pyrene decreases methylationISOHRC (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of HRC 5' UTR and Benzo(a)pyrene results in decreased methylation of HRC exonCTDPMID:27901495
HrcRatbenzo[a]pyrene affects methylationISOHRC (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of HRC promoterCTDPMID:27901495
HrcRatbenzo[a]pyrene increases methylationISOHRC (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of HRC 3' UTRCTDPMID:27901495
HrcRatbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of HRC mRNACTDPMID:25181051 and PMID:32145629

1 to 20 of 66 rows

Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
HrcRatcalcium ion homeostasis acts_upstream_of_or_withinISOHrc (Mus musculus)1624291 PMID:16600288RGDPMID:16600288
HrcRatnegative regulation of calcium ion import into sarcoplasmic reticulum  IMP 9685495 RGD 
HrcRatnegative regulation of cytosolic calcium ion concentration  IMP 9685495 RGD 
HrcRatpositive regulation of heart contraction involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
HrcRatpositive regulation of heart rate involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
HrcRatpositive regulation of relaxation of cardiac muscle involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
HrcRatregulation of calcium ion transmembrane transport involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
HrcRatregulation of cell communication by electrical coupling involved in cardiac conduction involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
HrcRatregulation of cytosolic calcium ion concentration involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
HrcRatregulation of heart contraction acts_upstream_of_or_withinISOHrc (Mus musculus)1624291 PMID:16600288RGDPMID:16600288
HrcRatregulation of heart rate involved_inISOHRC (Homo sapiens)1624291 PMID:18617481RGDPMID:18617481
HrcRatregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum involved_inISOHRC (Homo sapiens)1624291UniProtKB:B9EIW1 and PMID:24125847RGDPMID:24125847
1 to 12 of 12 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
HrcRatcytosol located_inISOHRC (Homo sapiens)1624291 RGDGO_REF:0000052
HrcRatendoplasmic reticulum located_inISOHRC (Homo sapiens)1624291 RGDGO_REF:0000052
HrcRatmitochondrion located_inISOHRC (Homo sapiens)1624291 RGDGO_REF:0000052
HrcRatsarcoplasmic reticulum membrane located_inISOHrc (Mus musculus)1624291 PMID:16600288RGDPMID:16600288
HrcRatZ disc located_inISOHRC (Homo sapiens)1624291 PMID:24125847RGDPMID:24125847

Molecular Function

  


#
Reference Title
Reference Citation
1. Increased Ca2+ storage capacity in the sarcoplasmic reticulum by overexpression of HRC (histidine-rich Ca2+ binding protein). Kim E, etal., Biochem Biophys Res Commun 2003 Jan 3;300(1):192-6.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
4. AAV-mediated knock-down of HRC exacerbates transverse aorta constriction-induced heart failure. Park CS, etal., PLoS One. 2012;7(8):e43282. doi: 10.1371/journal.pone.0043282. Epub 2012 Aug 28.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:15777620   PMID:16600288   PMID:17526652   PMID:18617481   PMID:24125847   PMID:35352799  



Hrc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,949,750 - 104,953,475 (+)NCBIGRCr8
mRatBN7.2195,813,262 - 95,816,987 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,813,253 - 95,816,984 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,198,707 - 101,202,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,671,382 - 109,675,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,961,782 - 102,965,504 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,324,788 - 101,328,391 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,324,652 - 101,328,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,388,311 - 102,391,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,805,143 - 95,808,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,883,253 - 95,886,857 (+)NCBI
Celera190,069,730 - 90,073,333 (+)NCBICelera
Cytogenetic Map1q22NCBI
HRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,151,198 - 49,155,396 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,151,198 - 49,155,396 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,654,455 - 49,658,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,346,267 - 54,350,493 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,346,269 - 54,350,476NCBI
Celera1946,521,679 - 46,525,908 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,030,689 - 46,034,918 (-)NCBIHuRef
CHM1_11949,656,583 - 49,660,812 (-)NCBICHM1_1
T2T-CHM13v2.01952,145,932 - 52,150,133 (-)NCBIT2T-CHM13v2.0
Hrc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,984,693 - 44,988,397 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,984,714 - 44,988,398 (+)EnsemblGRCm39 Ensembl
GRCm38745,335,269 - 45,338,973 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,335,290 - 45,338,974 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,590,639 - 52,594,343 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,203,443 - 45,207,015 (+)NCBIMGSCv36mm8
Celera740,791,527 - 40,795,231 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.26NCBI
Hrc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,583,876 - 1,587,355 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,583,661 - 1,587,457 (+)NCBIChiLan1.0ChiLan1.0
HRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,266,107 - 55,270,451 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,185,639 - 57,189,978 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,162,231 - 46,166,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,089,281 - 55,093,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,089,384 - 55,093,463 (-)Ensemblpanpan1.1panPan2
HRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,304,718 - 107,308,741 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,304,924 - 107,308,740 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,892,417 - 106,896,448 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,829,579 - 107,833,610 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,811,395 - 107,833,766 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,497,676 - 107,501,707 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,143,909 - 107,147,940 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,979,496 - 107,983,527 (+)NCBIUU_Cfam_GSD_1.0
Hrc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,470,024 - 21,473,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,083,602 - 3,092,308 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,088,072 - 3,092,034 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,337,347 - 54,341,625 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,337,348 - 54,341,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,986,764 - 49,990,919 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HRC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,372,758 - 42,378,273 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,372,861 - 42,377,267 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,265,945 - 22,271,134 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hrc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,938,074 - 4,941,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Hrc
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:66
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000028116
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 45 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000028116   ⟹   ENSRNOP00000028116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,813,253 - 95,816,977 (+)Ensembl
Rnor_6.0 Ensembl1101,324,652 - 101,328,435 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112846   ⟹   ENSRNOP00000097166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,813,422 - 95,815,889 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113100   ⟹   ENSRNOP00000084422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,813,253 - 95,816,984 (+)Ensembl
RefSeq Acc Id: NM_181369   ⟹   NP_852034
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,949,750 - 104,953,475 (+)NCBI
mRatBN7.2195,813,262 - 95,816,987 (+)NCBI
Rnor_6.01101,324,788 - 101,328,391 (+)NCBI
Rnor_5.01102,388,311 - 102,391,914 (+)NCBI
RGSC_v3.4195,805,143 - 95,808,746 (+)RGD
Celera190,069,730 - 90,073,333 (+)RGD
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_852034 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP31904 (Get FASTA)   NCBI Sequence Viewer  
  EDM07375 (Get FASTA)   NCBI Sequence Viewer  
  EDM07376 (Get FASTA)   NCBI Sequence Viewer  
  EDM07377 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028116
  ENSRNOP00000028116.3
  ENSRNOP00000084422.1
  ENSRNOP00000097166.1
1 to 9 of 9 rows
RefSeq Acc Id: NP_852034   ⟸   NM_181369
- Peptide Label: precursor
- UniProtKB: G3V8S6 (UniProtKB/TrEMBL),   A6JB08 (UniProtKB/TrEMBL),   Q80W59 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028116   ⟸   ENSRNOT00000028116
Ensembl Acc Id: ENSRNOP00000084422   ⟸   ENSRNOT00000113100
Ensembl Acc Id: ENSRNOP00000097166   ⟸   ENSRNOT00000112846

Name Modeler Protein Id AA Range Protein Structure
AF-G3V8S6-F1-model_v2 AlphaFold G3V8S6 1-754 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690034
Promoter ID:EPDNEW_R559
Type:multiple initiation site
Name:Hrc_1
Description:histidine rich calcium binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,324,712 - 101,324,772EPDNEW


1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59694 BioCyc
Ensembl Genes ENSRNOG00000020719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028116 ENTREZGENE
  ENSRNOT00000028116.6 UniProtKB/TrEMBL
  ENSRNOT00000112846.1 UniProtKB/TrEMBL
  ENSRNOT00000113100.1 UniProtKB/TrEMBL
InterPro His-rich_Ca-bd UniProtKB/TrEMBL
  Hist_rich_Ca-bd UniProtKB/TrEMBL
KEGG Report rno:292905 UniProtKB/TrEMBL
NCBI Gene 292905 ENTREZGENE
PANTHER HRCB UniProtKB/TrEMBL
  SARCOPLASMIC RETICULUM HISTIDINE-RICH CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
Pfam Hist_rich_Ca-bd UniProtKB/TrEMBL
PhenoGen Hrc PhenoGen
RatGTEx ENSRNOG00000020719 RatGTEx
UniProt A0A8I5ZZ96_RAT UniProtKB/TrEMBL
  A0A8I6AUL9_RAT UniProtKB/TrEMBL
  A6JB07_RAT UniProtKB/TrEMBL
  A6JB08 ENTREZGENE, UniProtKB/TrEMBL
  A6JB09_RAT UniProtKB/TrEMBL
  G3V8S6 ENTREZGENE, UniProtKB/TrEMBL
  Q80W59 ENTREZGENE, UniProtKB/TrEMBL
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Hrc  histidine rich calcium binding protein      Symbol and Name status set to approved 1299863 APPROVED