HRC (histidine rich calcium binding protein) - Rat Genome Database

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Gene: HRC (histidine rich calcium binding protein) Chlorocebus sabaeus
Analyze
Symbol: HRC
Name: histidine rich calcium binding protein
RGD ID: 18697479
Description: ENCODES a protein that exhibits ATPase binding (inferred); calcium ion binding (inferred); transmembrane transporter binding (inferred); INVOLVED IN calcium ion homeostasis (ortholog); negative regulation of calcium ion import into sarcoplasmic reticulum (ortholog); negative regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH Body Weight (ortholog); Brugada syndrome (ortholog); Cardiac Fibrosis (ortholog); FOUND IN sarcoplasmic reticulum membrane (inferred); Z disc (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sarcoplasmic reticulum histidine-rich calcium-binding protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,372,758 - 42,378,273 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,372,861 - 42,377,267 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,265,945 - 22,271,134 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HRC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,372,758 - 42,378,273 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,372,861 - 42,377,267 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,265,945 - 22,271,134 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
HRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,151,198 - 49,155,396 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,151,198 - 49,155,396 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,654,455 - 49,658,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,346,267 - 54,350,493 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,346,269 - 54,350,476NCBI
Celera1946,521,679 - 46,525,908 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,030,689 - 46,034,918 (-)NCBIHuRef
CHM1_11949,656,583 - 49,660,812 (-)NCBICHM1_1
T2T-CHM13v2.01952,145,932 - 52,150,133 (-)NCBIT2T-CHM13v2.0
Hrc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,984,693 - 44,988,397 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,984,714 - 44,988,398 (+)EnsemblGRCm39 Ensembl
GRCm38745,335,269 - 45,338,973 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,335,290 - 45,338,974 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,590,639 - 52,594,343 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,203,443 - 45,207,015 (+)NCBIMGSCv36mm8
Celera740,791,527 - 40,795,231 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.26NCBI
Hrc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,949,750 - 104,953,475 (+)NCBIGRCr8
mRatBN7.2195,813,262 - 95,816,987 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,813,253 - 95,816,984 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,198,707 - 101,202,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,671,382 - 109,675,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,961,782 - 102,965,504 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,324,788 - 101,328,391 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,324,652 - 101,328,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,388,311 - 102,391,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,805,143 - 95,808,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,883,253 - 95,886,857 (+)NCBI
Celera190,069,730 - 90,073,333 (+)NCBICelera
Cytogenetic Map1q22NCBI
Hrc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,583,876 - 1,587,355 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,583,661 - 1,587,457 (+)NCBIChiLan1.0ChiLan1.0
HRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,266,107 - 55,270,451 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,185,639 - 57,189,978 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,162,231 - 46,166,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,089,281 - 55,093,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,089,384 - 55,093,463 (-)Ensemblpanpan1.1panPan2
HRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,304,718 - 107,308,741 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,304,924 - 107,308,740 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,892,417 - 106,896,448 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,829,579 - 107,833,610 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,811,395 - 107,833,766 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,497,676 - 107,501,707 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,143,909 - 107,147,940 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,979,496 - 107,983,527 (+)NCBIUU_Cfam_GSD_1.0
Hrc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,470,024 - 21,473,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,083,602 - 3,092,308 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,088,072 - 3,092,034 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,337,347 - 54,341,625 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,337,348 - 54,341,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,986,764 - 49,990,919 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Hrc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,938,074 - 4,941,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 17 33 33 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000770   ⟹   ENSCSAP00000015294
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl642,372,861 - 42,377,267 (-)Ensembl
RefSeq Acc Id: XM_007997511   ⟹   XP_007995702
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1642,372,758 - 42,378,272 (-)NCBI
Vero_WHO_p1.0NW_02366607322,265,945 - 22,271,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007997512   ⟹   XP_007995703
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1642,372,758 - 42,378,273 (-)NCBI
Vero_WHO_p1.0NW_02366607322,265,945 - 22,271,134 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007995702 (Get FASTA)   NCBI Sequence Viewer  
  XP_007995703 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015294.1
RefSeq Acc Id: XP_007995703   ⟸   XM_007997512
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S355 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007995702   ⟸   XM_007997511
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S355 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000015294   ⟸   ENSCSAT00000000770


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002752 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000770.1 UniProtKB/TrEMBL
InterPro Hist_rich_Ca-bd UniProtKB/TrEMBL
  HRC UniProtKB/TrEMBL
  Osteopontin UniProtKB/TrEMBL
KEGG Report csab:103235023 UniProtKB/TrEMBL
NCBI Gene HRC ENTREZGENE
PANTHER PTHR15054 UniProtKB/TrEMBL
  SARCOPLASMIC RETICULUM HISTIDINE-RICH CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
Pfam Hist_rich_Ca-bd UniProtKB/TrEMBL
PRINTS OSTEOPONTIN UniProtKB/TrEMBL
UniProt A0A0D9S355 ENTREZGENE, UniProtKB/TrEMBL