Msi1 (musashi RNA-binding protein 1) - Rat Genome Database

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Gene: Msi1 (musashi RNA-binding protein 1) Rattus norvegicus
Analyze
Symbol: Msi1
Name: musashi RNA-binding protein 1
RGD ID: 628778
Description: Predicted to enable RNA binding activity; molecular condensate scaffold activity; and protein homodimerization activity. Involved in epithelial cell differentiation and response to hormone. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Biomarker of brain infarction and brain ischemia. Orthologous to human MSI1 (musashi RNA binding protein 1); PARTICIPATES IN mRNA decay pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Msi1h; Musashi homolog 1(Drosophila); musashi-1; RNA-binding protein Musashi homolog 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,815,225 - 46,911,852 (-)NCBIGRCr8
mRatBN7.21241,158,301 - 41,251,134 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,158,599 - 41,191,076 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,329,615 - 42,351,639 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,943,282 - 42,965,305 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,003,827 - 42,025,850 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01246,899,835 - 46,935,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1246,895,447 - 46,920,952 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,696,700 - 48,731,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,425,957 - 42,462,517 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,289,344 - 42,310,487 (-)NCBI
Celera1242,786,001 - 42,821,164 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Msi1Ratbrain infarction  IEP 1582664 RGD 
Msi1Ratbrain ischemia  IEP 633285 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Msi1Ratshort chain acyl-CoA dehydrogenase deficiency  ISOMSI1 (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of butyryl-CoA dehydrogenaseClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Msi1Rat1,2-dimethylhydrazine multiple interactionsISOMsi1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MSI1 mRNACTDPMID:22206623
Msi1Rat17beta-estradiol increases expressionISOMSI1 (Homo sapiens)6480464Estradiol results in increased expression of MSI1 mRNA and Estradiol results in increased expression of MSI1 proteinCTDPMID:27271280
Msi1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MSI1 mRNACTDPMID:19490992 and PMID:33387578
Msi1Rat3,3',5-triiodo-L-thyronine multiple interactionsISOMsi1 (Mus musculus)6480464[pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of MSI1 mRNACTDPMID:34289950
Msi1Rat4,4'-sulfonyldiphenol decreases methylationISOMsi1 (Mus musculus)6480464bisphenol S results in decreased methylation of MSI1 exonCTDPMID:33297965
Msi1Rat4,4'-sulfonyldiphenol affects methylationISOMsi1 (Mus musculus)6480464bisphenol S affects the methylation of MSI1 geneCTDPMID:31683443
Msi1Rat5-aza-2'-deoxycytidine decreases expressionISOMSI1 (Homo sapiens)6480464Decitabine results in decreased expression of MSI1 mRNACTDPMID:19363521
Msi1Rat5-aza-2'-deoxycytidine multiple interactionsISOMSI1 (Homo sapiens)6480464TP53 protein affects the reaction [Decitabine results in decreased expression of MSI1 mRNA]CTDPMID:19363521
Msi1Ratall-trans-retinoic acid affects expressionISOMSI1 (Homo sapiens)6480464Tretinoin affects the expression of MSI1 mRNACTDPMID:15498508
Msi1Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MSI1 mRNACTDPMID:35163327
Msi1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of MSI1 mRNACTDPMID:16483693
Msi1Ratarsenous acid multiple interactionsISOMSI1 (Homo sapiens)6480464Arsenic Trioxide promotes the reaction [MSI1 protein binds to EIF2AK2 protein modified form] more ...CTDPMID:29486283
Msi1Ratbenzo[a]pyrene decreases methylationISOMsi1 (Mus musculus)6480464Benzo(a)pyrene results in decreased methylation of MSI1 intronCTDPMID:27901495
Msi1Ratbenzo[a]pyrene increases methylationISOMSI1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of MSI1 promoterCTDPMID:27901495
Msi1Ratbis(2-ethylhexyl) phthalate multiple interactionsISOMSI1 (Homo sapiens)6480464[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of MSI1 geneCTDPMID:33872906
Msi1Ratbisphenol A decreases expressionISOMsi1 (Mus musculus)6480464bisphenol A results in decreased expression of MSI1 mRNACTDPMID:22687993 and PMID:35278557
Msi1Ratbisphenol A decreases methylationISOMSI1 (Homo sapiens)6480464bisphenol A results in decreased methylation of MSI1 geneCTDPMID:31601247
Msi1Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of MSI1 mRNACTDPMID:34947998
Msi1Ratbisphenol A multiple interactionsISOMSI1 (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in increased methylation of MSI1 gene and IGF1 protein inhibits the reaction [bisphenol A results in decreased expression of MSI1 mRNA]CTDPMID:27271280 and PMID:31601247
Msi1Ratbisphenol A decreases expressionISOMSI1 (Homo sapiens)6480464bisphenol A results in decreased expression of MSI1 mRNA and bisphenol A results in decreased expression of MSI1 proteinCTDPMID:27271280

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Msi1Ratcentral nervous system development involved_inIBAPANTHER:PTN004472241 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Msi1Ratepithelial cell differentiation  IEP 1582662 RGD 
Msi1Ratregulation of translation involved_inIBAFB:FBgn0011666 and PANTHER:PTN0044722391600115GO_REF:0000033GO_CentralGO_REF:0000033
Msi1Ratresponse to hormone  IMP 1582665 RGD 

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Msi1Ratcytoplasm located_inIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Msi1Ratcytoplasm located_inISOMsi1 (Mus musculus)1624291 PMID:11588182 and PMID:15076722RGDPMID:11588182 and PMID:15076722
Msi1Ratcytoplasm is_active_inIBAMGI:107376 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Msi1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Msi1Ratnucleus located_inIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Msi1Ratnucleus located_inISOMsi1 (Mus musculus)1624291 PMID:15076722RGDPMID:15076722
Msi1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
1 to 9 of 9 rows

Molecular Function
1 to 19 of 19 rows

  
Object Symbol
Species
Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Msi1Ratidentical protein binding enablesISOMSI1 (Homo sapiens)1624291UniProtKB:O43347 and PMID:30367664RGDPMID:30367664
Msi1Ratidentical protein binding enablesIEAUniProtKB:O43347 and ensembl:ENSP000002575521600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratidentical protein binding enablesISOMsi1 (Mus musculus)1624291UniProtKB:Q61474 and PMID:26197342RGDPMID:26197342
Msi1Ratidentical protein binding enablesIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratmolecular condensate scaffold activity enablesIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratmolecular condensate scaffold activity enablesISOMsi1 (Mus musculus)1624291 PMID:32225071RGDPMID:32225071
Msi1RatmRNA binding enablesIBAPANTHER:PTN004472239 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Msi1Ratnucleic acid binding enablesIEAInterPro:IPR0359791600115GO_REF:0000002InterProGO_REF:0000002
Msi1Ratpoly(U) RNA binding enablesIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratpoly(U) RNA binding enablesISOMsi1 (Mus musculus)1624291 PMID:11588182RGDPMID:11588182
Msi1Ratprotein binding enablesISOMSI1 (Homo sapiens)1624291UniProtKB:P10636-8 more ...RGDPMID:30367664 and PMID:32296183
Msi1Ratprotein homodimerization activity enablesIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratprotein homodimerization activity enablesISOMsi1 (Mus musculus)1624291 PMID:32225071RGDPMID:32225071
Msi1RatRNA binding enablesIEAUniRule:UR0004146191600115GO_REF:0000104UniProtGO_REF:0000104
Msi1RatRNA binding  NAS 633285 RGD 
Msi1RatRNA binding enablesIEAInterPro:IPR000504 and InterPro:IPR0341261600115GO_REF:0000002InterProGO_REF:0000002
Msi1RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Msi1Ratsingle-stranded RNA binding enablesIEAUniProtKB:Q61474 and ensembl:ENSMUSP000001205161600115GO_REF:0000107EnsemblGO_REF:0000107
Msi1Ratsingle-stranded RNA binding enablesISOMsi1 (Mus musculus)1624291 PMID:11588182RGDPMID:11588182
1 to 19 of 19 rows

Imported Annotations - KEGG (archival)

Object Symbol
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Term
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Reference
Notes
Source
Original Reference(s)
Msi1RatmRNA decay pathway  IEA 6907045 KEGGrno:03015

1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Regulation of tau RNA maturation by thyroid hormone is mediated by the neural RNA-binding protein musashi-1. Cuadrado A, etal., Mol Cell Neurosci. 2002 Jun;20(2):198-210.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution. Nagata H, etal., FEBS Lett. 2006 Jan 9;580(1):27-33. Epub 2005 Dec 6.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia. Yagita Y, etal., J Neurosci Res 2002 Sep 15;69(6):750-6.
10. Proliferation and differentiation of neural stem cells in adult rats after cerebral infarction. Zhang B, etal., Chin Med Sci J. 2004 Jun;19(2):73-7.
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PMID:11588182   PMID:15076722   PMID:22681889   PMID:23236886   PMID:23374535   PMID:25888190   PMID:26197342   PMID:30367664   PMID:33810326   PMID:33843023  



Msi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,815,225 - 46,911,852 (-)NCBIGRCr8
mRatBN7.21241,158,301 - 41,251,134 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,158,599 - 41,191,076 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,329,615 - 42,351,639 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,943,282 - 42,965,305 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,003,827 - 42,025,850 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01246,899,835 - 46,935,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1246,895,447 - 46,920,952 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,696,700 - 48,731,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,425,957 - 42,462,517 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,289,344 - 42,310,487 (-)NCBI
Celera1242,786,001 - 42,821,164 (-)NCBICelera
Cytogenetic Map12q16NCBI
MSI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,339,662 - 120,369,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,341,330 - 120,369,164 (-)EnsemblGRCh38hg38GRCh38
GRCh3712120,779,133 - 120,806,967 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,263,516 - 119,291,341 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412119,241,852 - 119,269,678NCBI
Celera12120,412,237 - 120,440,052 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12117,787,331 - 117,814,272 (-)NCBIHuRef
CHM1_112120,747,072 - 120,774,927 (-)NCBICHM1_1
T2T-CHM13v2.012120,326,839 - 120,356,341 (-)NCBIT2T-CHM13v2.0
Msi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,567,734 - 115,593,757 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,567,658 - 115,593,757 (+)EnsemblGRCm39 Ensembl
GRCm385115,359,059 - 115,455,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,429,599 - 115,455,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv375115,879,694 - 115,904,211 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,690,684 - 115,715,201 (+)NCBIMGSCv36mm8
Celera5112,528,152 - 112,553,235 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.09NCBI
Msi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545511,268,650 - 11,298,378 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545511,269,486 - 11,298,342 (+)NCBIChiLan1.0ChiLan1.0
MSI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,402,554 - 128,430,509 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,398,931 - 128,426,786 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012117,915,879 - 117,943,772 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,289,281 - 121,316,276 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,289,281 - 121,316,276 (-)Ensemblpanpan1.1panPan2
MSI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,266,302 - 16,288,980 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,266,586 - 16,289,012 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,270,168 - 16,292,838 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,533,308 - 16,556,005 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,533,366 - 16,555,993 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,494,719 - 16,517,389 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,571,374 - 16,594,034 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,614,085 - 16,635,848 (-)NCBIUU_Cfam_GSD_1.0
Msi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118146,074,570 - 146,097,615 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668573,453 - 596,696 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668573,459 - 595,278 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,331,377 - 40,356,788 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,331,371 - 40,356,793 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21442,789,298 - 42,812,679 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MSI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111115,691,313 - 115,719,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037129,383,701 - 129,411,767 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Msi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474713,291,071 - 13,316,532 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474713,290,999 - 13,316,410 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Msi1
557 total Variants

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:55
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000001532
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 40 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat

1 to 10 of 40 rows
AW533646  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,191,132 - 41,191,293 (+)MAPPERmRatBN7.2
mRatBN7.21241,191,132 - 41,191,684 (+)MAPPERmRatBN7.2
Rnor_6.01246,927,866 - 46,928,417NCBIRnor6.0
Rnor_6.01246,927,866 - 46,928,026NCBIRnor6.0
Rnor_5.01248,724,520 - 48,725,071UniSTSRnor5.0
Rnor_5.01248,724,520 - 48,724,680UniSTSRnor5.0
RGSC_v3.41242,455,048 - 42,455,208UniSTSRGSC3.4
RGSC_v3.41242,455,048 - 42,455,599UniSTSRGSC3.4
Celera1242,813,849 - 42,814,400UniSTS
Celera1242,813,849 - 42,814,009UniSTS
RH 3.4 Map12772.12UniSTS
Cytogenetic Map12q16UniSTS
RH134213  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,190,227 - 41,190,408 (+)MAPPERmRatBN7.2
Rnor_6.01246,926,961 - 46,927,141NCBIRnor6.0
Rnor_5.01248,723,615 - 48,723,795UniSTSRnor5.0
RGSC_v3.41242,454,143 - 42,454,323UniSTSRGSC3.4
Celera1242,812,944 - 42,813,124UniSTS
Cytogenetic Map12q16UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 90 89 58 25 58 6 217 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000001532   ⟹   ENSRNOP00000001532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,158,599 - 41,191,076 (-)Ensembl
Rnor_6.0 Ensembl1246,895,447 - 46,920,952 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117406   ⟹   ENSRNOP00000084373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,158,599 - 41,191,076 (-)Ensembl
RefSeq Acc Id: NM_148890   ⟹   NP_683688
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,845,425 (-)NCBI
mRatBN7.21241,158,301 - 41,184,690 (-)NCBI
Rnor_6.01246,899,835 - 46,935,335 (-)NCBI
Rnor_5.01248,696,700 - 48,731,989 (-)NCBI
RGSC_v3.41242,425,957 - 42,462,517 (-)RGD
Celera1242,786,001 - 42,821,164 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089120   ⟹   XP_038945048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,845,436 (-)NCBI
mRatBN7.21241,158,301 - 41,184,704 (-)NCBI
RefSeq Acc Id: XM_039089121   ⟹   XP_038945049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,845,436 (-)NCBI
mRatBN7.21241,158,301 - 41,184,704 (-)NCBI
RefSeq Acc Id: XM_039089122   ⟹   XP_038945050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,845,436 (-)NCBI
mRatBN7.21241,158,301 - 41,184,704 (-)NCBI
RefSeq Acc Id: XM_039089123   ⟹   XP_038945051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,842,452 (-)NCBI
mRatBN7.21241,158,301 - 41,181,749 (-)NCBI
RefSeq Acc Id: XM_039089124   ⟹   XP_038945052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,839,664 (-)NCBI
mRatBN7.21241,158,301 - 41,178,582 (-)NCBI
RefSeq Acc Id: XM_039089125   ⟹   XP_038945053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,911,852 (-)NCBI
mRatBN7.21241,158,301 - 41,251,134 (-)NCBI
RefSeq Acc Id: XM_063271088   ⟹   XP_063127158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,815,225 - 46,845,436 (-)NCBI
RefSeq Acc Id: XM_063271090   ⟹   XP_063127160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,839,669 (-)NCBI
RefSeq Acc Id: XM_063271091   ⟹   XP_063127161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,819,039 - 46,839,673 (-)NCBI
RefSeq Acc Id: XR_010056363
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,815,225 - 46,845,436 (-)NCBI
RefSeq Acc Id: XR_010056364
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,815,225 - 46,845,436 (-)NCBI
1 to 5 of 12 rows
1 to 5 of 12 rows
RefSeq Acc Id: NP_683688   ⟸   NM_148890
- UniProtKB: Q8K3P4 (UniProtKB/Swiss-Prot),   A6J1U2 (UniProtKB/TrEMBL),   F1LRH1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001532   ⟸   ENSRNOT00000001532
RefSeq Acc Id: XP_038945053   ⟸   XM_039089125
- Peptide Label: isoform X7
- UniProtKB: A6J1U2 (UniProtKB/TrEMBL),   F1LRH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945050   ⟸   XM_039089122
- Peptide Label: isoform X4
- UniProtKB: A6J1U2 (UniProtKB/TrEMBL),   F1LRH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945049   ⟸   XM_039089121
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GAA4 (UniProtKB/TrEMBL),   A6J1U2 (UniProtKB/TrEMBL),   F1LRH1 (UniProtKB/TrEMBL)
RRM

Name Modeler Protein Id AA Range Protein Structure
AF-Q8K3P4-F1-model_v2 AlphaFold Q8K3P4 1-362 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-18993 BioCyc
Ensembl Genes ENSRNOG00000001156 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001532 ENTREZGENE
  ENSRNOT00000001532.6 UniProtKB/Swiss-Prot
  ENSRNOT00000117406 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
InterPro MSI_RRM2 UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
KEGG Report rno:259272 UniProtKB/Swiss-Prot
NCBI Gene 259272 ENTREZGENE
PANTHER RNA-BINDING PROTEIN MUSASHI HOMOLOG 1 UniProtKB/Swiss-Prot
  RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 UniProtKB/Swiss-Prot
Pfam RRM_1 UniProtKB/Swiss-Prot
PhenoGen Msi1 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001156 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt A0A8I6GAA4 ENTREZGENE, UniProtKB/TrEMBL
  A6J1U2 ENTREZGENE, UniProtKB/TrEMBL
  F1LRH1 ENTREZGENE, UniProtKB/TrEMBL
  MSI1H_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-02 Msi1  musashi RNA-binding protein 1  Msi1  Musashi homolog 1(Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-16 Msi1  Musashi homolog 1(Drosophila)  Msi1h  musashi homolog 1(Drosophila)  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-01-20 Msi1h  musashi homolog 1(Drosophila)    Musashi homolog 1(Drosophila)  Name updated 1299863 APPROVED
2003-02-27 Msi1h  Musashi homolog 1(Drosophila)      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression expressed in neural stem cells 633285