Lgals2 (galectin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Lgals2 (galectin 2) Rattus norvegicus
Analyze
Symbol: Lgals2
Name: galectin 2
RGD ID: 621269
Description: Enables galactoside binding activity. Predicted to be involved in several processes, including T cell homeostasis; positive regulation of apoptotic process; and positive regulation of inflammatory response. Predicted to be part of galectin complex. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human LGALS2 (galectin 2); PARTICIPATES IN myocardial infarction pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: gal-2; galectin-2; lectin galactoside-binding soluble 2 (galectin 2); lectin, galactoside-binding, soluble 2; lectin, galactoside-binding, soluble, 2; lectin, galactoside-binding, soluble, 2 (galectin 2)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,283,630 - 112,290,228 (-)NCBIGRCr8
mRatBN7.27110,403,171 - 110,410,046 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,403,173 - 110,404,802 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,153,320 - 112,159,807 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,376,850 - 114,383,337 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,345,224 - 114,351,701 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,071,122 - 120,077,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,071,124 - 120,077,612 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,062,255 - 120,069,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,811,332 - 116,817,822 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,845,563 - 116,852,052 (-)NCBI
Celera7106,737,582 - 106,744,072 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,6-dinitrotoluene  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
cefaloridine  (EXP)
chlordecone  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibenzofurans  (ISO)
dicrotophos  (ISO)
dimethylarsinic acid  (ISO)
flutamide  (EXP)
furan  (EXP)
genistein  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
lipopolysaccharide  (ISO)
methylarsonic acid  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nitrofen  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP)
PCB138  (EXP)
pinostrobin  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
rotenone  (EXP)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
galectin complex  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Effects of lymphotoxin-alpha gene and galectin 2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules, and risk of coronary heart disease. Asselbergs FW, etal., Clin Sci (Lond). 2006 Oct 16;.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Identification and cloning of rat galectin-2: expression is predominantly in epithelial cells of the stomach. Oka T, etal., Arch Biochem Biophys 1999 Jan 15;361(2):195-201.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro. Ozaki K, etal., Nature. 2004 May 6;429(6987):72-5.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18064431  


Genomics

Comparative Map Data
Lgals2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,283,630 - 112,290,228 (-)NCBIGRCr8
mRatBN7.27110,403,171 - 110,410,046 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,403,173 - 110,404,802 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,153,320 - 112,159,807 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,376,850 - 114,383,337 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,345,224 - 114,351,701 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,071,122 - 120,077,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,071,124 - 120,077,612 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,062,255 - 120,069,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,811,332 - 116,817,822 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,845,563 - 116,852,052 (-)NCBI
Celera7106,737,582 - 106,744,072 (-)NCBICelera
Cytogenetic Map7q34NCBI
LGALS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,570,248 - 37,580,087 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,570,248 - 37,582,616 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,966,255 - 37,976,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,296,199 - 36,305,970 (-)NCBINCBI36Build 36hg18NCBI36
Build 342236,290,753 - 36,300,524NCBI
Celera2221,768,112 - 21,777,886 (-)NCBICelera
Cytogenetic Map22q13.1ENTREZGENE
HuRef2220,933,465 - 20,943,235 (-)NCBIHuRef
CHM1_12237,924,981 - 37,934,762 (-)NCBICHM1_1
T2T-CHM13v2.02238,031,510 - 38,041,349 (-)NCBIT2T-CHM13v2.0
Lgals2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,735,060 - 78,739,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,735,060 - 78,739,729 (-)EnsemblGRCm39 Ensembl
GRCm381578,850,860 - 78,855,529 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,850,860 - 78,855,529 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,681,290 - 78,685,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,578,396 - 79,579,182 (-)NCBIMGSCv36mm8
MGSCv361578,678,117 - 78,682,784 (-)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Lgals2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,988,193 - 23,989,703 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,988,193 - 24,001,868 (-)NCBIChiLan1.0ChiLan1.0
LGALS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,430,416 - 47,440,663 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,119,399 - 50,130,636 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,488,257 - 18,498,401 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,320,775 - 36,330,281 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,320,775 - 36,330,281 (-)Ensemblpanpan1.1panPan2
LGALS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,012,534 - 27,015,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,010,550 - 27,015,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,967,191 - 26,970,371 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,804,386 - 27,807,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,804,368 - 27,807,840 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,526,563 - 27,529,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,835,255 - 27,838,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,012,763 - 28,015,944 (+)NCBIUU_Cfam_GSD_1.0
Lgals2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,453,091 - 10,478,358 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,483,572 - 3,488,730 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,463,195 - 3,500,431 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGALS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,237,745 - 10,250,162 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,237,772 - 10,244,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,795,590 - 7,802,388 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LGALS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,275,277 - 20,287,978 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045105,540,698 - 105,550,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lgals2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,319,011 - 10,321,069 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,315,705 - 10,321,253 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lgals2
52 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:87
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000011750
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat

Markers in Region
RH130148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,403,026 - 110,403,182 (+)MAPPERmRatBN7.2
Rnor_6.07120,070,978 - 120,071,133NCBIRnor6.0
Rnor_5.07120,062,111 - 120,062,266UniSTSRnor5.0
RGSC_v3.47116,811,188 - 116,811,343UniSTSRGSC3.4
Celera7106,737,438 - 106,737,593UniSTS
RH 3.4 Map7838.5UniSTS
Cytogenetic Map7q34UniSTS
RH128291  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,403,199 - 110,403,410 (+)MAPPERmRatBN7.2
Rnor_6.07120,071,151 - 120,071,361NCBIRnor6.0
Rnor_5.07120,062,284 - 120,062,494UniSTSRnor5.0
RGSC_v3.47116,811,361 - 116,811,571UniSTSRGSC3.4
Celera7106,737,611 - 106,737,821UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 26 26 26 10
Low 1 9 24 15 10 15 2 2 5 21 24 11 2
Below cutoff 12 6 8 5 6 11 2 15 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011750   ⟹   ENSRNOP00000011750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,403,173 - 110,404,802 (-)Ensembl
Rnor_6.0 Ensembl7120,071,124 - 120,077,612 (-)Ensembl
RefSeq Acc Id: NM_133599   ⟹   NP_598283
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,283,633 - 112,290,123 (-)NCBI
mRatBN7.27110,403,171 - 110,409,662 (-)NCBI
Rnor_6.07120,071,122 - 120,077,612 (-)NCBI
Rnor_5.07120,062,255 - 120,069,133 (-)NCBI
RGSC_v3.47116,811,332 - 116,817,822 (-)RGD
Celera7106,737,582 - 106,744,072 (-)RGD
Sequence:
RefSeq Acc Id: XM_039078346   ⟹   XP_038934274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,283,630 - 112,290,228 (-)NCBI
mRatBN7.27110,403,231 - 110,410,046 (-)NCBI
Protein Sequences
Protein RefSeqs NP_598283 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934274 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA74954 (Get FASTA)   NCBI Sequence Viewer  
  EDM15846 (Get FASTA)   NCBI Sequence Viewer  
  EDM15847 (Get FASTA)   NCBI Sequence Viewer  
  EDM15848 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011750.4
GenBank Protein Q9Z144 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_598283   ⟸   NM_133599
- UniProtKB: Q9Z144 (UniProtKB/Swiss-Prot),   A6HSM4 (UniProtKB/TrEMBL),   A6HSM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011750   ⟸   ENSRNOT00000011750
RefSeq Acc Id: XP_038934274   ⟸   XM_039078346
- Peptide Label: isoform X1
Protein Domains
Galectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z144-F1-model_v2 AlphaFold Q9Z144 1-130 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695469
Promoter ID:EPDNEW_R5993
Type:single initiation site
Name:Lgals2_1
Description:galectin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07120,077,637 - 120,077,697EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621269 AgrOrtholog
BioCyc Gene G2FUF-32796 BioCyc
Ensembl Genes ENSRNOG00000008539 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011750.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galectin_CRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 171134 ENTREZGENE
PANTHER GALECTIN-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11346 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Gal-bind_lectin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lgals2 PhenoGen
PROSITE GALECTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008539 RatGTEx
SMART Gal-bind_lectin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2Q5R2_RAT UniProtKB/TrEMBL
  A6HSM4 ENTREZGENE, UniProtKB/TrEMBL
  A6HSM5 ENTREZGENE, UniProtKB/TrEMBL
  A6HSM6_RAT UniProtKB/TrEMBL
  LEG2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Lgals2  galectin 2  Lgals2  galectin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-18 Lgals2  galectin 2  Lgals2  lectin, galactoside-binding, soluble, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-10-22 Lgals2  lectin, galactoside-binding, soluble, 2  Lgals2  lectin, galactoside-binding, soluble 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Lgals2  lectin, galactoside-binding, soluble 2    lectin, galactoside-binding, soluble, 2 (galectin 2)  Name updated 1299863 APPROVED
2002-08-07 Lgals2  lectin, galactoside-binding, soluble, 2 (galectin 2)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the epithelial cells of the stomach and in intestine 633279