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Gene: GNAQ (G protein subunit alpha q) Homo sapiens
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Symbol: GNAQ
Name: G protein subunit alpha q
Description: Exhibits GTPase activator activity. Involved in negative regulation of protein kinase activity; protein stabilization; and regulation of canonical Wnt signaling pathway. Localizes to the extracellular exosome and lysosomal membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CMC1; G-ALPHA-q; GAQ; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide-binding protein alpha-q; guanine nucleotide-binding protein G(q) subunit alpha; heterotrimeric guanine nucleotide-binding protein alpha q subunit; SWS
Orthologs:
Mus musculus (house mouse) : Gnaq (guanine nucleotide binding protein, alpha q polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnaq (G protein subunit alpha q)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnaq (G protein subunit alpha q)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986730 (guanine nucleotide-binding protein G(q) subunit alpha)
Canis lupus familiaris (dog) : GNAQ (G protein subunit alpha q)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnaq (G protein subunit alpha q)
Sus scrofa (pig) : GNAQ (G protein subunit alpha q)
Chlorocebus sabaeus (African green monkey) : GNAQ (G protein subunit alpha q)
Heterocephalus glaber (naked mole-rat) : Gnaq (G protein subunit alpha q)
more info ...
Related Pseudogenes: GNAQP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl977,716,097 - 78,031,811 (-)Ensembl
GRCh38977,716,097 - 78,031,811 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37980,335,189 - 80,646,219 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36979,525,009 - 79,836,012 (-)NCBINCBI36hg18NCBI36
Build 34977,564,746 - 77,875,746NCBI
Celera950,912,294 - 51,223,287 (-)NCBI
Cytogenetic Map9q21.2NCBI
HuRef950,167,421 - 50,477,535 (-)NCBIHuRef
CHM1_1980,478,436 - 80,793,818 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GNAQ
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731425
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.