Gtf2a2 (general transcription factor 2A subunit 2) - Rat Genome Database

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Gene: Gtf2a2 (general transcription factor 2A subunit 2) Rattus norvegicus
Analyze
Symbol: Gtf2a2
Name: general transcription factor 2A subunit 2
RGD ID: 620720
Description: Predicted to enable several functions, including RNA polymerase II general transcription initiation factor activity; general transcription initiation factor binding activity; and protein dimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription factor TFIIA complex and transcription factor TFIID complex. Orthologous to human GTF2A2 (general transcription factor IIA subunit 2); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 4-tert-Octylphenol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: general transcription factor IIa 2; general transcription factor IIA subunit 2; general transcription factor IIA, 2; general transcription factor IIa, 2 (12kD subunit); general transcription factor2A subunit 2; MGC188808; TFIIA-gamma; transcription initiation factor IIA gamma chain; transcription initiation factor IIA subunit 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8879,542,682 - 79,556,484 (+)NCBIGRCr8
mRatBN7.2870,662,447 - 70,675,576 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl870,662,428 - 70,675,569 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,628,292 - 67,628,621 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,133,660 - 67,133,989 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0872,311,551 - 72,320,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0876,422,341 - 76,435,587 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl876,422,359 - 76,435,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0876,640,681 - 76,653,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4874,447,866 - 74,456,735 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1874,466,919 - 74,475,789 (+)NCBI
Celera871,051,449 - 71,060,316 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2a2RatBloom syndrome  ISOGTF2A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:28492532
Gtf2a2Ratcolorectal cancer  ISOGTF2A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2a2Rat(+)-catechin multiple interactionsISOGTF2A2 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of GTF2A2 mRNACTDPMID:24763279
Gtf2a2Rat1,2-dichloroethane decreases expressionISOGtf2a2 (Mus musculus)6480464ethylene dichloride results in decreased expression of GTF2A2 mRNACTDPMID:28960355
Gtf2a2Rat1,2-dimethylhydrazine decreases expressionISOGtf2a2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of GTF2A2 mRNACTDPMID:22206623
Gtf2a2Rat1,2-dimethylhydrazine multiple interactionsISOGtf2a2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GTF2A2 mRNACTDPMID:22206623
Gtf2a2Rat17beta-estradiol decreases expressionISOGtf2a2 (Mus musculus)6480464Estradiol results in decreased expression of GTF2A2 mRNACTDPMID:39298647
Gtf2a2Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOGtf2a2 (Mus musculus)64804642 more ...CTDPMID:30294300
Gtf2a2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGtf2a2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of GTF2A2 mRNACTDPMID:21889950
Gtf2a2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGtf2a2 (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of GTF2A2 mRNACTDPMID:25975270
Gtf2a2Rat2-hydroxypropanoic acid decreases expressionISOGTF2A2 (Homo sapiens)6480464Lactic Acid results in decreased expression of GTF2A2 mRNACTDPMID:30851411
Gtf2a2Rat4,4'-diaminodiphenylmethane decreases expressionISOGtf2a2 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of GTF2A2 mRNACTDPMID:18648102
Gtf2a2Rat4-tert-Octylphenol increases expressionEXP 64804644-tert-octylphenol results in increased expression of GTF2A2 mRNACTDPMID:17011747
Gtf2a2Ratacrylamide increases expressionISOGTF2A2 (Homo sapiens)6480464Acrylamide results in increased expression of GTF2A2 mRNACTDPMID:32763439
Gtf2a2Ratall-trans-retinoic acid decreases expressionISOGTF2A2 (Homo sapiens)6480464Tretinoin results in decreased expression of GTF2A2 proteinCTDPMID:16646664
Gtf2a2Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of GTF2A2 mRNACTDPMID:16483693
Gtf2a2Ratarsenite(3-) multiple interactionsISOGTF2A2 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to GTF2A2 mRNA]CTDPMID:32406909
Gtf2a2Ratbenzo[a]pyrene increases methylationISOGTF2A2 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of GTF2A2 promoterCTDPMID:27901495
Gtf2a2Ratbeta-lapachone increases expressionISOGTF2A2 (Homo sapiens)6480464beta-lapachone results in increased expression of GTF2A2 mRNACTDPMID:38218311
Gtf2a2Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of GTF2A2 mRNACTDPMID:25181051 and PMID:31129395
Gtf2a2Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of GTF2A2 mRNACTDPMID:34947998
Gtf2a2Ratbisphenol A increases expressionISOGtf2a2 (Mus musculus)6480464bisphenol A results in increased expression of GTF2A2 mRNACTDPMID:38074096

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Biological Process
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Cellular Component
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2a2Ratcytosol located_inISOGTF2A2 (Homo sapiens)1624291 RGDGO_REF:0000052
Gtf2a2Ratnucleoplasm located_inISOGTF2A2 (Homo sapiens)1624291 RGDGO_REF:0000052
Gtf2a2Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Gtf2a2Ratnucleus located_inISOGTF2A2 (Homo sapiens)1624291 PMID:10022900RGDPMID:10022900
Gtf2a2Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Gtf2a2Rattranscription factor TFIIA complex part_ofISOGTF2A2 (Homo sapiens)1624291 PMID:7724559 more ...RGDPMID:7724559 more ...
Gtf2a2Rattranscription factor TFIIA complex part_ofIBAFB:FBgn0013347 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gtf2a2Rattranscription factor TFIIA complex part_ofIEAInterPro:IPR003194 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Gtf2a2Rattranscription factor TFIIA complex part_ofIEAInterPro:IPR003194 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Gtf2a2Rattranscription factor TFIID complex part_ofISOGTF2A2 (Homo sapiens)1624291 PMID:27193682RGDPMID:27193682
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Molecular Function
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RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2a2RatRNA polymerase II transcription initiation pathway  ISOGTF2A2 (Homo sapiens)9681721 RGD 

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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Structural insights into transcription initiation by RNA polymerase II. Grunberg S and Hahn S, Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11.
4. TFIIAalpha/beta-like factor is encoded by a germ cell-specific gene whose expression is up-regulated with other general transcription factors during spermatogenesis in the mouse. Han SY, etal., Biol Reprod 2001 Feb;64(2):507-17.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2. Yu S, etal., J Biol Chem. 2008 Feb 29;283(9):5542-53. doi: 10.1074/jbc.M705653200. Epub 2008 Jan 2.
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PMID:1302244   PMID:7724559   PMID:7958899   PMID:7958900   PMID:8626665   PMID:12477932   PMID:19235719   PMID:27193682  



Gtf2a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8879,542,682 - 79,556,484 (+)NCBIGRCr8
mRatBN7.2870,662,447 - 70,675,576 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl870,662,428 - 70,675,569 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,628,292 - 67,628,621 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,133,660 - 67,133,989 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0872,311,551 - 72,320,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0876,422,341 - 76,435,587 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl876,422,359 - 76,435,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0876,640,681 - 76,653,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4874,447,866 - 74,456,735 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1874,466,919 - 74,475,789 (+)NCBI
Celera871,051,449 - 71,060,316 (-)NCBICelera
Cytogenetic Map8q24NCBI
GTF2A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381559,638,062 - 59,657,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1559,638,062 - 59,657,541 (-)EnsemblGRCh38hg38GRCh38
GRCh371559,930,261 - 59,949,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361557,718,358 - 57,736,987 (-)NCBINCBI36Build 36hg18NCBI36
Build 341557,718,357 - 57,736,985NCBI
Celera1536,818,236 - 36,837,689 (-)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1536,752,262 - 36,771,682 (-)NCBIHuRef
CHM1_11560,048,219 - 60,067,695 (-)NCBICHM1_1
T2T-CHM13v2.01557,439,769 - 57,459,225 (-)NCBIT2T-CHM13v2.0
Gtf2a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39969,919,830 - 69,930,148 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl969,919,832 - 69,930,148 (+)EnsemblGRCm39 Ensembl
GRCm38970,012,548 - 70,022,866 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl970,012,550 - 70,022,866 (+)EnsemblGRCm38mm10GRCm38
MGSCv37969,860,357 - 69,870,654 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36969,811,714 - 69,822,011 (+)NCBIMGSCv36mm8
Celera967,229,001 - 67,239,301 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map939.18NCBI
Gtf2a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545015,181,824 - 15,195,594 (+)NCBIChiLan1.0ChiLan1.0
GTF2A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21648,902,349 - 48,922,048 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11553,085,842 - 53,104,641 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01538,608,360 - 38,627,156 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11556,913,452 - 56,932,051 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1556,913,452 - 56,932,052 (-)Ensemblpanpan1.1panPan2
GTF2A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13024,502,825 - 24,522,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3024,484,701 - 24,522,207 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3024,476,918 - 24,496,309 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03024,671,512 - 24,691,163 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3024,671,512 - 24,691,398 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13024,597,440 - 24,616,848 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03024,679,848 - 24,699,256 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03024,867,205 - 24,886,587 (-)NCBIUU_Cfam_GSD_1.0
Gtf2a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640102,788,934 - 102,803,926 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647120,636,202 - 20,652,013 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647120,636,997 - 20,651,986 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1112,390,594 - 112,402,265 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11112,371,276 - 112,399,541 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21124,288,264 - 124,316,522 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12623,850,483 - 23,868,477 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048117,459,828 - 117,477,971 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478112,498,702 - 12,512,810 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478112,498,057 - 12,510,701 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gtf2a2
15 total Variants


Assembly: RGSC_v3.4
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
8 74447873 74447874 A G snv WN/N (KNAW), MR/N (KNAW), M520/N (KNAW), LE/Stm (KNAW), FHL/EurMcwi (MCW), ACI/N (KNAW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (MCW), FHH/EurMcwi (MCW), BUF/N (KNAW) View more Information
8 74447918 74447919 G A snv ACI/EurMcwi (MCW), FHL/EurMcwi (MCW) View more Information
8 74449130 74449131 A G snv LCR/2Mco (UMich), HCR/2Mco (UMich), LCR/1Mco (UMich), HCR/1Mco (UMich), FHL/EurMcwi (MCW), ACI/EurMcwi (MCW) View more Information
8 74449161 74449162 A T snv ACI/EurMcwi (MCW), FHL/EurMcwi (MCW), M520/N (KNAW), LCR/2Mco (UMich), LCR/1Mco (UMich), HCR/1Mco (UMich), HCR/2Mco (UMich) View more Information
8 74449171 74449172 A C snv SS/JrHsdMcwi (MCW), ACI/N (KNAW), BN/SsN (KNAW), BN/NHsdMcwi (KNAW), ACI/EurMcwi (MCW), LE/Stm (KNAW), M520/N (KNAW), FHL/EurMcwi (MCW), F344/NRrrc (KNAW) View more Information


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
8 76649881 76649882 C T snv ACI/EurMcwi (MCW), FHL/EurMcwi (MCW) View more Information
8 76649926 76649927 T C snv ACI/EurMcwi (MCW), FHL/EurMcwi (MCW) View more Information


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
8 76426342 76426343 A G snv MR/N (MCW), WN/N (MCW), M520/N (MCW), Buf/N (MCW), ACI/N (MCW) View more Information
8 76427630 76427631 A T snv M520/N (MCW) View more Information
8 76427640 76427641 A C snv M520/N (MCW), BN/SsN (MCW), ACI/N (MCW), F344/NRrrc (MCW) View more Information

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:124
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000014706
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat

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RH128620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2870,675,419 - 70,675,611 (+)MAPPERmRatBN7.2
Rnor_6.0876,435,325 - 76,435,516NCBIRnor6.0
Rnor_5.0876,640,752 - 76,640,943UniSTSRnor5.0
RGSC_v3.4874,456,857 - 74,457,048UniSTSRGSC3.4
Celera871,051,136 - 71,051,327UniSTS
Cytogenetic Map8q24UniSTS
BF390041  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2870,671,233 - 70,671,355 (+)MAPPERmRatBN7.2
Rnor_6.0876,431,139 - 76,431,260NCBIRnor6.0
Rnor_5.0876,645,008 - 76,645,129UniSTSRnor5.0
RGSC_v3.4874,452,671 - 74,452,792UniSTSRGSC3.4
Celera871,055,392 - 71,055,513UniSTS
Cytogenetic Map8q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 11 43 82 57 60 41 19 41 160 73 74 35 41 19


1 to 16 of 16 rows
RefSeq Transcripts NM_001412186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_178067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF000944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 16 of 16 rows

Ensembl Acc Id: ENSRNOT00000084148   ⟹   ENSRNOP00000071778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl870,662,456 - 70,675,569 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085496   ⟹   ENSRNOP00000068825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl870,662,428 - 70,675,568 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112984   ⟹   ENSRNOP00000077033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl870,662,428 - 70,675,302 (+)Ensembl
RefSeq Acc Id: NM_001412186   ⟹   NP_001399115
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,355 - 79,556,484 (+)NCBI
mRatBN7.2870,662,447 - 70,675,576 (+)NCBI
RefSeq Acc Id: NM_053345   ⟹   NP_445797
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,355 - 79,556,484 (+)NCBI
mRatBN7.2870,662,447 - 70,675,576 (+)NCBI
Rnor_6.0876,426,335 - 76,435,203 (+)NCBI
Rnor_5.0876,640,681 - 76,653,942 (-)NCBI
RGSC_v3.4874,447,866 - 74,456,735 (+)RGD
Celera871,051,449 - 71,060,316 (-)RGD
Sequence:
RefSeq Acc Id: NR_178067
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,355 - 79,556,484 (+)NCBI
mRatBN7.2870,662,447 - 70,675,576 (+)NCBI
RefSeq Acc Id: XM_039082206   ⟹   XP_038938134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,499 - 79,556,484 (+)NCBI
mRatBN7.2870,665,433 - 70,675,576 (+)NCBI
RefSeq Acc Id: XM_063266219   ⟹   XP_063122289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,542,682 - 79,556,484 (+)NCBI
RefSeq Acc Id: XM_063266220   ⟹   XP_063122290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,479 - 79,556,484 (+)NCBI
RefSeq Acc Id: XM_063266221   ⟹   XP_063122291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,542,682 - 79,553,345 (+)NCBI
RefSeq Acc Id: XM_063266222   ⟹   XP_063122292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,542,682 - 79,552,438 (+)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_445797   ⟸   NM_053345
- UniProtKB: O08950 (UniProtKB/Swiss-Prot),   A6KEU8 (UniProtKB/TrEMBL),   A6KEU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038938134   ⟸   XM_039082206
- Peptide Label: isoform X2
- UniProtKB: O08950 (UniProtKB/Swiss-Prot),   A6KEU8 (UniProtKB/TrEMBL),   A6KEU9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000071778   ⟸   ENSRNOT00000084148
Ensembl Acc Id: ENSRNOP00000068825   ⟸   ENSRNOT00000085496
Ensembl Acc Id: ENSRNOP00000077033   ⟸   ENSRNOT00000112984
Transcription initiation factor IIA gamma subunit C-   Transcription initiation factor IIA gamma subunit N-

Name Modeler Protein Id AA Range Protein Structure
AF-O08950-F1-model_v2 AlphaFold O08950 1-109 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696105
Promoter ID:EPDNEW_R6627
Type:multiple initiation site
Name:LOC103695118_1
Description:transcription initiation factor IIA subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0876,422,353 - 76,422,413EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29946 BioCyc
Ensembl Genes ENSRNOG00000056701 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000085496 ENTREZGENE
  ENSRNOT00000085496.2 UniProtKB/Swiss-Prot
  ENSRNOT00000115150 ENTREZGENE
Gene3D-CATH 1.10.287.190 UniProtKB/Swiss-Prot
  2.30.18.10 UniProtKB/Swiss-Prot
InterPro TFIIA_a-hlx UniProtKB/Swiss-Prot
  TFIIA_b-brl UniProtKB/Swiss-Prot
  TFIIA_gsu UniProtKB/Swiss-Prot
  TFIIA_gsu_C UniProtKB/Swiss-Prot
  TFIIA_gsu_N UniProtKB/Swiss-Prot
KEGG Report rno:83828 UniProtKB/Swiss-Prot
NCBI Gene 83828 ENTREZGENE
PANTHER PTHR10966 UniProtKB/Swiss-Prot
Pfam TFIIA_gamma_C UniProtKB/Swiss-Prot
  TFIIA_gamma_N UniProtKB/Swiss-Prot
PhenoGen Gtf2a2 PhenoGen
PIRSF Hum_TFIIA_gamma UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000056701 RatGTEx
Superfamily-SCOP SSF50784 UniProtKB/Swiss-Prot
  Transcription factor IIA (TFIIA), alpha-helical domain UniProtKB/Swiss-Prot
UniProt A0A0G2K1B8_RAT UniProtKB/TrEMBL
  A0A8I5ZJD1_RAT UniProtKB/TrEMBL
  A6KEU4_RAT UniProtKB/TrEMBL
  A6KEU5_RAT UniProtKB/TrEMBL
  A6KEU8 ENTREZGENE, UniProtKB/TrEMBL
  A6KEU9 ENTREZGENE, UniProtKB/TrEMBL
  A6KEV1 ENTREZGENE, UniProtKB/TrEMBL
  B5DEM4 ENTREZGENE, UniProtKB/TrEMBL
  O08950 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-18 Gtf2a2  general transcription factor 2A subunit 2  Gtf2a2  general transcription factor2A subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-04 Gtf2a2  general transcription factor2A subunit 2  Gtf2a2  general transcription factor IIA, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Gtf2a2  general transcription factor IIA, 2  Gtf2a2  general transcription factor IIa 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Gtf2a2  general transcription factor Iia 2    general transcription factor IIa, 2 (12kD subunit)  Name updated 1299863 APPROVED
2002-08-07 Gtf2a2  general transcription factor IIa, 2 (12kD subunit)      Symbol and Name status set to provisional 70820 PROVISIONAL