Insl6 (insulin-like 6) - Rat Genome Database

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Gene: Insl6 (insulin-like 6) Rattus norvegicus
Analyze
Symbol: Insl6
Name: insulin-like 6
RGD ID: 62061
Description: Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within several processes, including flagellated sperm motility; male gonad development; and spermatid development. Predicted to be located in extracellular region. Orthologous to human INSL6 (insulin like 6); INTERACTS WITH 17beta-estradiol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: insulin-like peptide 6; insulin-like peptide INSL6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,483,530 - 236,487,065 (-)NCBIGRCr8
mRatBN7.21227,069,958 - 227,073,493 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,069,958 - 227,073,493 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,471,624 - 235,475,151 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,401,288 - 242,404,815 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,218,731 - 235,222,261 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,473,292 - 247,476,827 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,473,292 - 247,476,827 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,721,416 - 254,724,951 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,990,534 - 232,994,069 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,154,556 - 233,158,092 (-)NCBI
Celera1224,221,875 - 224,225,410 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 14 of 14 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Insl6Ratacute myeloid leukemia  ISOINSL6 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15781101 more ...
Insl6RatBudd-Chiari syndrome  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Budd-Chiari syndromeClinVarPMID:15781101 more ...
Insl6Ratchromosome 9p deletion syndrome  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 9p deletion syndromeClinVarPMID:25741868
Insl6Ratfamilial erythrocytosis 1  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Erythrocytosis autosomal dominant benignClinVarPMID:15781101 more ...
Insl6Ratgenetic disease  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:24728327 more ...
Insl6Rathereditary breast ovarian cancer syndrome  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Breast-ovarian cancer more ...ClinVarPMID:25741868
Insl6RatHereditary Neoplastic Syndromes  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromeClinVarPMID:25741868 and PMID:28492532
Insl6Ratmyelofibrosis  ISOINSL6 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15781101 more ...
Insl6Ratmyeloid neoplasm  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Myeloproliferative disorderClinVarPMID:15781101 more ...
Insl6Ratpolycythemia  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: ERYTHROCYTOSIS and SOMATICClinVarPMID:15781101 more ...
Insl6Ratpolycythemia vera  ISOINSL6 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15781101 more ...
Insl6Ratprimary ovarian insufficiency  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Premature ovarian failureClinVarPMID:25741868
Insl6RatSplenomegaly  ISOINSL6 (Homo sapiens)8554872ClinVar Annotator: match by term: Enlarged SpleenClinVarPMID:15781101 more ...
Insl6RatThrombocythemia 3  ISOINSL6 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15781101 more ...
1 to 14 of 14 rows

1 to 20 of 54 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Insl6Rat(1->4)-beta-D-glucan multiple interactionsISOInsl6 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of INSL6 mRNACTDPMID:36331819
Insl6Rat1,2-dimethylhydrazine decreases expressionISOInsl6 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of INSL6 mRNACTDPMID:22206623
Insl6Rat1,2-dimethylhydrazine multiple interactionsISOInsl6 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of INSL6 mRNACTDPMID:22206623
Insl6Rat17alpha-ethynylestradiol affects expressionISOInsl6 (Mus musculus)6480464Ethinyl Estradiol affects the expression of INSL6 mRNACTDPMID:17555576
Insl6Rat17alpha-ethynylestradiol multiple interactionsISOInsl6 (Mus musculus)6480464[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of INSL6 mRNACTDPMID:37844793
Insl6Rat17beta-estradiol multiple interactionsEXP 6480464[Testosterone co-treated with Estradiol] results in increased expression of INSL6 mRNACTDPMID:32741896
Insl6Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOInsl6 (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of INSL6 mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of INSL6 mRNACTDPMID:16214954 and PMID:25975270
Insl6Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOInsl6 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of INSL6 mRNACTDPMID:18796159 more ...
Insl6Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOInsl6 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of INSL6 mRNACTDPMID:20702594 more ...
Insl6Rat2,3,7,8-Tetrachlorodibenzofuran affects expressionISOInsl6 (Mus musculus)64804642 more ...CTDPMID:20702594
Insl6Rat3,3',4,4',5-pentachlorobiphenyl affects expressionISOInsl6 (Mus musculus)64804643 more ...CTDPMID:20702594
Insl6Rat4-hydroxyphenyl retinamide decreases expressionISOInsl6 (Mus musculus)6480464Fenretinide results in decreased expression of INSL6 mRNACTDPMID:28973697
Insl6Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of INSL6 mRNACTDPMID:16483693
Insl6Ratarsane affects methylationISOINSL6 (Homo sapiens)6480464Arsenic affects the methylation of INSL6 geneCTDPMID:25304211
Insl6Ratarsenic atom affects methylationISOINSL6 (Homo sapiens)6480464Arsenic affects the methylation of INSL6 geneCTDPMID:25304211
Insl6Ratarsenite(3-) decreases methylationISOINSL6 (Homo sapiens)6480464arsenite results in decreased methylation of INSL6 promoterCTDPMID:23974009
Insl6Ratarsenite(3-) increases expressionISOINSL6 (Homo sapiens)6480464arsenite results in increased expression of INSL6 mRNACTDPMID:23974009
Insl6Ratbenzo[a]pyrene increases expressionISOInsl6 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of INSL6 mRNACTDPMID:19770486 more ...
Insl6Ratbenzo[a]pyrene decreases methylationISOINSL6 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of INSL6 exonCTDPMID:27901495
Insl6Ratbenzo[a]pyrene increases methylationISOINSL6 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of INSL6 promoterCTDPMID:27901495

1 to 20 of 54 rows

Biological Process
1 to 11 of 11 rows

  
1 to 11 of 11 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Insl6Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Insl6Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Insl6Ratextracellular region located_inIEAInterPro:IPR016179 and InterPro:IPR0171001600115GO_REF:0000002InterProGO_REF:0000002

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Insl6Rathormone activity enablesIEAUniProtKB-KW:KW-03721600115GO_REF:0000043UniProtGO_REF:0000043
Insl6Rathormone activity enablesIEAInterPro:IPR016179 and InterPro:IPR0171001600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Identification of INSL6, a new member of the insulin family that is expressed in the testis of the human and rat. Lok S, etal., Biol Reprod 2000 Jun;62(6):1593-9.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
PMID:19520787  



Insl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,483,530 - 236,487,065 (-)NCBIGRCr8
mRatBN7.21227,069,958 - 227,073,493 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,069,958 - 227,073,493 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,471,624 - 235,475,151 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,401,288 - 242,404,815 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,218,731 - 235,222,261 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,473,292 - 247,476,827 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,473,292 - 247,476,827 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,721,416 - 254,724,951 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,990,534 - 232,994,069 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,154,556 - 233,158,092 (-)NCBI
Celera1224,221,875 - 224,225,410 (-)NCBICelera
Cytogenetic Map1q52NCBI
INSL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3894,991,976 - 5,185,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl95,123,880 - 5,185,647 (-)EnsemblGRCh38hg38GRCh38
GRCh3795,163,868 - 5,185,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3695,153,863 - 5,175,618 (-)NCBINCBI36Build 36hg18NCBI36
Build 3495,153,864 - 5,175,618NCBI
Celera95,089,480 - 5,111,235 (-)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef95,119,294 - 5,141,049 (-)NCBIHuRef
CHM1_195,164,034 - 5,185,789 (-)NCBICHM1_1
T2T-CHM13v2.094,992,955 - 5,190,714 (-)NCBIT2T-CHM13v2.0
Insl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,298,754 - 29,302,718 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,298,744 - 29,302,756 (-)EnsemblGRCm39 Ensembl
GRCm381929,321,354 - 29,325,318 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,321,344 - 29,325,356 (-)EnsemblGRCm38mm10GRCm38
MGSCv371929,395,844 - 29,399,808 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361929,387,351 - 29,391,315 (-)NCBIMGSCv36mm8
Celera1930,097,916 - 30,101,880 (-)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1923.82NCBI
Insl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554349,349,142 - 9,355,739 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554349,349,033 - 9,355,817 (-)NCBIChiLan1.0ChiLan1.0
INSL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211119,362,748 - 119,434,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19119,368,695 - 119,390,561 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v095,007,158 - 5,029,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.195,192,023 - 5,213,827 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl95,192,023 - 5,213,827 (-)Ensemblpanpan1.1panPan2
INSL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,457,854 - 93,474,777 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,459,945 - 93,474,793 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha193,866,056 - 93,882,980 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0194,011,512 - 94,028,434 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl194,011,678 - 94,028,449 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,643,885 - 93,660,812 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,368,454 - 93,385,388 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0194,132,819 - 94,149,742 (-)NCBIUU_Cfam_GSD_1.0
Insl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947141,095,258 - 141,105,131 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493650367,933 - 78,496 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INSL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,792,787 - 216,823,479 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,792,785 - 216,820,197 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,534,691 - 242,561,841 (+)NCBISscrofa10.2Sscrofa10.2susScr3
INSL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11274,345,243 - 74,372,778 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1274,346,706 - 74,372,729 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603862,743,906 - 62,770,088 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Insl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247369,838,781 - 9,848,514 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Insl6
18 total Variants

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:27
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000021298
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 77 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464234238494Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat

1 to 10 of 77 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 8 13 69 46 47 25 25 25 6 117 51 57 26 53 22



Ensembl Acc Id: ENSRNOT00000021298   ⟹   ENSRNOP00000021298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1227,069,958 - 227,073,493 (-)Ensembl
Rnor_6.0 Ensembl1247,473,292 - 247,476,827 (-)Ensembl
RefSeq Acc Id: NM_022583   ⟹   NP_072105
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81236,483,530 - 236,487,065 (-)NCBI
mRatBN7.21227,069,958 - 227,073,493 (-)NCBI
Rnor_6.01247,473,292 - 247,476,827 (-)NCBI
Rnor_5.01254,721,416 - 254,724,951 (-)NCBI
RGSC_v3.41232,990,534 - 232,994,069 (-)RGD
Celera1224,221,875 - 224,225,410 (-)RGD
Sequence:
Protein RefSeqs NP_072105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD40956 (Get FASTA)   NCBI Sequence Viewer  
  EDM13088 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021298
  ENSRNOP00000021298.3
GenBank Protein Q9WV41 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_072105   ⟸   NM_022583
- Peptide Label: precursor
- UniProtKB: Q9WV41 (UniProtKB/Swiss-Prot),   A6I0V7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021298   ⟸   ENSRNOT00000021298
Insulin-like

Name Modeler Protein Id AA Range Protein Structure
AF-Q9WV41-F1-model_v2 AlphaFold Q9WV41 1-188 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690844
Promoter ID:EPDNEW_R1369
Type:multiple initiation site
Name:Insl6_1
Description:insulin-like 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01247,476,781 - 247,476,841EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-55972 BioCyc
Ensembl Genes ENSRNOG00000015868 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021298 ENTREZGENE
  ENSRNOT00000021298.5 UniProtKB/Swiss-Prot
Gene3D-CATH Insulin-like UniProtKB/Swiss-Prot
InterPro Insulin-like UniProtKB/Swiss-Prot
  Insulin-like_pep_6 UniProtKB/Swiss-Prot
  Insulin-like_sf UniProtKB/Swiss-Prot
  Insulin_CS UniProtKB/Swiss-Prot
  Repro_Hormone_Insulin-like UniProtKB/Swiss-Prot
KEGG Report rno:50546 UniProtKB/Swiss-Prot
NCBI Gene 50546 ENTREZGENE
PANTHER PTHR12004:SF1 UniProtKB/Swiss-Prot
  RELAXIN UniProtKB/Swiss-Prot
Pfam Insulin UniProtKB/Swiss-Prot
PhenoGen Insl6 PhenoGen
PIRSF Insulin-like_peptide_6 UniProtKB/Swiss-Prot
PROSITE INSULIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015868 RatGTEx
SMART IlGF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56994 UniProtKB/Swiss-Prot
TIGR TC214189
UniProt A6I0V7 ENTREZGENE, UniProtKB/TrEMBL
  INSL6_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Insl6  insulin-like 6      Name updated 70584 APPROVED

Note Type Note Reference
gene_domains has an insulin family B-chain cysteine motif 61639
gene_expression expressed in the seminiferous tubules in spermatocytes and round spermatids in the testis 61639
gene_product member of the insulin family 61639
gene_protein encodes a 188 amino acid protein 61639
gene_protein has dibasic sequence at the junction of the C-peptide and A-chain suggesting the requirement of multiple prohormone convertases to form a mature hormone 61639