Plcb4 (phospholipase C, beta 4) - Rat Genome Database

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Gene: Plcb4 (phospholipase C, beta 4) Rattus norvegicus
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Symbol: Plcb4
Name: phospholipase C, beta 4
RGD ID: 3345
Description: Enables mitogen-activated protein kinase binding activity. Involved in negative regulation of potassium ion transport. Predicted to be located in dendrite; nucleus; and plasma membrane. Predicted to be active in several cellular components, including glutamatergic synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density. Orthologous to human PLCB4 (phospholipase C beta 4); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; Beta4aa; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-4; Phospholipase C (BETA4); Phospholipase C beta4; phospholipase C-beta-4; PLC-beta-4; RATBETA4AA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Plcb4_v1   Plcb4_v2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83143,405,721 - 143,775,129 (+)NCBIGRCr8
mRatBN7.23122,952,965 - 123,322,522 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3122,953,196 - 123,322,392 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3126,861,256 - 127,230,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03135,448,283 - 135,807,045 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03133,116,870 - 133,485,687 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03128,601,163 - 128,971,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3128,756,799 - 128,971,746 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03135,089,551 - 135,459,248 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43123,706,313 - 124,077,381 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13123,611,885 - 123,982,941 (+)NCBI
Celera3121,694,557 - 122,062,160 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
Plcb4RatALAGILLE SYNDROME 1  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Alagille syndrome due to a JAG1 point mutationClinVarPMID:10213047 more ...
Plcb4RatAuriculocondylar Syndrome  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Auriculocondylar syndromeClinVarPMID:16114046 more ...
Plcb4RatAuriculocondylar Syndrome 1  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Auriculocondylar syndrome 1ClinVarPMID:16114046 more ...
Plcb4RatAuriculocondylar Syndrome 2  ISOPLCB4 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16114046 more ...
Plcb4Ratcongenital myasthenic syndrome 18  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: MYASTHENIC SYNDROME more ...ClinVarPMID:28492532 and PMID:32733715
Plcb4Ratdevelopmental and epileptic encephalopathy 12  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 12ClinVarPMID:10213047 more ...
Plcb4Ratdevelopmental and epileptic encephalopathy 12  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Early infantile epileptic encephalopathy 12ClinVarPMID:28492532 and PMID:32733715
Plcb4Ratgenetic disease  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:16114046 more ...
Plcb4Ratlong QT syndrome  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:26132555
Plcb4Ratprostate cancer  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVarPMID:23265383
Plcb4Ratuveal melanoma  ISOPLCB4 (Homo sapiens)8554872ClinVar Annotator: match by term: Uveal melanomaClinVarPMID:31186267
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Original Reference(s)
Plcb4RatAuriculocondylar Syndrome  ISOPLCB4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Plcb4Ratmelanoma  ISOPLCB4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21499247
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Original Reference(s)
Plcb4RatAuriculocondylar Syndrome 2  ISOPLCB4 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Plcb4Rat(+)-catechin multiple interactionsISOPLCB4 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PLCB4 mRNACTDPMID:24763279
Plcb4Rat(+)-pilocarpine increases expressionISOPlcb4 (Mus musculus)6480464Pilocarpine results in increased expression of PLCB4 proteinCTDPMID:18774262
Plcb4Rat1,2-dichloroethane decreases expressionISOPlcb4 (Mus musculus)6480464ethylene dichloride results in decreased expression of PLCB4 mRNACTDPMID:28960355
Plcb4Rat1,3-dinitrobenzene decreases expressionEXP 64804643-dinitrobenzene results in decreased expression of PLCB4 proteinCTDPMID:24140754
Plcb4Rat17beta-estradiol multiple interactionsISOPLCB4 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of PLCB4 mRNACTDPMID:30165855
Plcb4Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOPlcb4 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Plcb4Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOPlcb4 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Plcb4Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOPlcb4 (Mus musculus)64804642 more ...CTDPMID:31388691
Plcb4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPLCB4 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of PLCB4 mRNACTDPMID:22574217
Plcb4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PLCB4 mRNACTDPMID:34747641
Plcb4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPlcb4 (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of PLCB4 mRNACTDPMID:25975270
Plcb4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPlcb4 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PLCB4 mRNACTDPMID:24680724
Plcb4Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expressionISOPLCB4 (Homo sapiens)64804642 more ...CTDPMID:26705709
Plcb4Rat3,3',4,4',5-pentachlorobiphenyl decreases expressionEXP 64804643 more ...CTDPMID:23196670 and PMID:32119087
Plcb4Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PLCB4 mRNACTDPMID:24780913 more ...
Plcb4Rataconitine decreases expressionEXP 6480464Aconitine results in decreased expression of PLCB4 proteinCTDPMID:33236894
Plcb4Rataflatoxin B1 decreases methylationISOPLCB4 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PLCB4 intronCTDPMID:30157460
Plcb4RatAflatoxin B2 alpha increases methylationISOPLCB4 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of PLCB4 intronCTDPMID:30157460
Plcb4Rataflatoxin M1 decreases expressionISOPLCB4 (Homo sapiens)6480464Aflatoxin M1 results in decreased expression of PLCB4 mRNACTDPMID:30928695
Plcb4Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of PLCB4 mRNACTDPMID:30047161

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Biological Process
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Original Reference(s)
Plcb4Ratintracellular signal transduction involved_inIEAInterPro:IPR001192 and InterPro:IPR0017111600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratlipid catabolic process involved_inIEAUniProtKB-KW:KW-04421600115GO_REF:0000043UniProtGO_REF:0000043
Plcb4Ratlipid catabolic process involved_inIEAInterPro:IPR0148151600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Plcb4Ratlipid metabolic process involved_inIEAInterPro:IPR001711 and InterPro:IPR0179461600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratmodulation of chemical synaptic transmission involved_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratmodulation of chemical synaptic transmission involved_inISOPlcb4 (Mus musculus)1624291 PMID:11551922RGDPMID:11551922
Plcb4Ratnegative regulation of potassium ion transport  IMP 2299873 RGD 
Plcb4Ratphosphatidylinositol metabolic process involved_inIBAFB:FBgn0262738 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plcb4Ratphosphatidylinositol-mediated signaling involved_inIBAPANTHER:PTN000036885 and UniProtKB:Q4KWH81600115GO_REF:0000033GO_CentralGO_REF:0000033
Plcb4Ratphospholipase C-activating endothelin receptor signaling pathway involved_inISSUniProtKB:Q151471600115GO_REF:0000024UniProtGO_REF:0000024
Plcb4Ratphospholipase C-activating endothelin receptor signaling pathway involved_inISOPLCB4 (Homo sapiens)1624291 PMID:35284927RGDPMID:35284927
Plcb4Ratphototransduction  NAS 633574 RGD 
Plcb4Ratrelease of sequestered calcium ion into cytosol involved_inIBAMGI:97616 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plcb4Ratsignal transduction involved_inIEAInterPro:IPR0017111600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043
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Cellular Component
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Original Reference(s)
Plcb4Ratdendrite located_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratdendrite located_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
Plcb4Ratglutamatergic synapse is_active_inISOPlcb4 (Mus musculus)1624291 PMID:11551922RGDPMID:11551922
Plcb4Ratglutamatergic synapse is_active_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Plcb4Ratnucleus located_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratnucleus located_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
Plcb4Ratparallel fiber to Purkinje cell synapse is_active_inISOPlcb4 (Mus musculus)1624291 PMID:11551922RGDPMID:11551922
Plcb4Ratparallel fiber to Purkinje cell synapse is_active_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratplasma membrane located_inISOPLCB4 (Homo sapiens)1624291 PMID:35284927RGDPMID:35284927
Plcb4Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Plcb4Ratplasma membrane located_inISSUniProtKB:Q151471600115GO_REF:0000024UniProtGO_REF:0000024
Plcb4Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Plcb4Ratpostsynapse is_active_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
Plcb4Ratpostsynapse is_active_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratpostsynaptic density located_inIEAUniProtKB:Q91UZ1 and ensembl:ENSMUSP000001057361600115GO_REF:0000107EnsemblGO_REF:0000107
Plcb4Ratpostsynaptic density located_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
Plcb4Ratpostsynaptic density is_active_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
Plcb4Ratsmooth endoplasmic reticulum is_active_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
Plcb4Ratsmooth endoplasmic reticulum located_inISOPlcb4 (Mus musculus)1624291 PMID:15579147RGDPMID:15579147
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Molecular Function
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Original Reference(s)
Plcb4Ratcalcium ion binding enablesIEAInterPro:IPR014815 and InterPro:IPR0162801600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratcalcium ion binding enablesIEAUniRule:UR0009547621600115GO_REF:0000104UniProtGO_REF:0000104
Plcb4Ratcalcium ion binding enablesIEAInterPro:IPR0162801600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Plcb4Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Plcb4Ratmitogen-activated protein kinase binding  IPIMapk1 (Rattus norvegicus)2299872 RGD 
Plcb4Ratphosphatidylinositol-4,5-bisphosphate phospholipase C activity enablesIEAUniRule:UR0009547621600115GO_REF:0000104UniProtGO_REF:0000104
Plcb4Ratphosphatidylinositol-4,5-bisphosphate phospholipase C activity enablesIEAInterPro:IPR001711 and InterPro:IPR0162801600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratphosphatidylinositol-4,5-bisphosphate phospholipase C activity enablesIBAFB:FBgn0262738 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plcb4Ratphosphatidylinositol-4,5-bisphosphate phospholipase C activity enablesIEAInterPro:IPR001711 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratphosphatidylinositol-4,5-bisphosphate phospholipase C activity enablesIEAEC:3.1.4.111600115GO_REF:0000003UniProtGO_REF:0000003
Plcb4Ratphosphatidylinositol-4,5-bisphosphate phospholipase C activity enablesIEARHEA:331791600115GO_REF:0000116RHEAGO_REF:0000116
Plcb4Ratphosphoric diester hydrolase activity enablesIEAInterPro:IPR0179461600115GO_REF:0000002InterProGO_REF:0000002
Plcb4Ratprotein binding enablesISOPLCB4 (Homo sapiens)1624291UniProtKB:Q04864 more ...RGDPMID:25416956 and PMID:32296183
Plcb4Ratprotein binding enablesISOPlcb4 (Mus musculus)1624291PR:P11881 more ...RGDPMID:15579147
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RGD Manual Annotations


  
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Original Reference(s)
Plcb4RatG protein mediated signaling pathway via Galphaq family  ISOPLCB4 (Homo sapiens)5131495 RGD 
Plcb4Ratprotein kinase C (PKC) signaling pathway   ISOPLCB4 (Homo sapiens)5131502 RGD 

Imported Annotations - KEGG (archival)

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#
Reference Title
Reference Citation
1. A unique isoform of phospholipase Cbeta4 highly expressed in the cerebellum and eye. Adamski FM, etal., Biochim Biophys Acta 1999 Jan 18;1444(1):55-60.
2. Fear conditioning is associated with altered integration of PLC and ERK signaling in the hippocampus. Buckley CT and Caldwell KK, Pharmacol Biochem Behav. 2004 Dec;79(4):633-40.
3. Stimulation of 5-HT(2) receptors in prefrontal pyramidal neurons inhibits Ca(v)1.2 L type Ca(2+) currents via a PLCbeta/IP3/calcineurin signaling cascade. Day M, etal., J Neurophysiol 2002 May;87(5):2490-504.
4. Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme? Drin G and Scarlata S, Cell Signal. 2007 Jul;19(7):1383-92. Epub 2007 Apr 29.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4. Haley JE, etal., J Neurosci. 2000 Nov 1;20(21):RC105.
7. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
8. Cloning of cDNA encoding rat phospholipase C-beta 4, a new member of the phospholipase C. Kim MJ, etal., Biochem Biophys Res Commun 1993 Jul 30;194(2):706-12.
9. A cytosolic, galphaq- and betagamma-insensitive splice variant of phospholipase C-beta4. Kim MJ, etal., J Biol Chem 1998 Feb 6;273(6):3618-24.
10. Purification, molecular cloning, and sequencing of phospholipase C-beta 4. Lee CW, etal., J Biol Chem 1993 Oct 5;268(28):21318-27.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. Translation of clock rhythmicity into neural firing in suprachiasmatic nucleus requires mGluR-PLCbeta4 signaling. Park D, etal., Nat Neurosci 2003 Apr;6(4):337-8.
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Regulation of phosphoinositide-specific phospholipase C. Rhee SG Annu Rev Biochem. 2001;70:281-312.
19. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
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PMID:11551922   PMID:15579147   PMID:15738151   PMID:19826069   PMID:19856080   PMID:23503970  



Plcb4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83143,405,721 - 143,775,129 (+)NCBIGRCr8
mRatBN7.23122,952,965 - 123,322,522 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3122,953,196 - 123,322,392 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3126,861,256 - 127,230,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03135,448,283 - 135,807,045 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03133,116,870 - 133,485,687 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03128,601,163 - 128,971,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3128,756,799 - 128,971,746 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03135,089,551 - 135,459,248 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43123,706,313 - 124,077,381 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13123,611,885 - 123,982,941 (+)NCBI
Celera3121,694,557 - 122,062,160 (+)NCBICelera
Cytogenetic Map3q36NCBI
PLCB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38209,068,678 - 9,480,808 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl209,067,825 - 9,504,593 (+)EnsemblGRCh38hg38GRCh38
GRCh37209,049,325 - 9,461,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36209,024,932 - 9,409,463 (+)NCBINCBI36Build 36hg18NCBI36
Build 34209,024,931 - 9,409,460NCBI
Celera209,119,817 - 9,531,474 (+)NCBICelera
Cytogenetic Map20p12.3-p12.2NCBI
HuRef209,001,542 - 9,413,398 (+)NCBIHuRef
CHM1_1209,050,899 - 9,462,613 (+)NCBICHM1_1
T2T-CHM13v2.0209,111,633 - 9,523,716 (+)NCBIT2T-CHM13v2.0
Plcb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392135,500,523 - 135,856,522 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2135,500,931 - 135,856,513 (+)EnsemblGRCm39 Ensembl
GRCm382135,658,603 - 136,014,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2135,659,011 - 136,014,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv372135,567,566 - 135,838,804 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362135,433,271 - 135,704,509 (+)NCBIMGSCv36mm8
Celera2136,939,191 - 137,211,347 (+)NCBICelera
Cytogenetic Map2F3NCBI
cM Map266.64NCBI
Plcb4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541519,310,917 - 19,463,098 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541519,108,120 - 19,462,084 (+)NCBIChiLan1.0ChiLan1.0
PLCB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2219,967,849 - 10,403,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1209,964,676 - 10,400,261 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0209,042,127 - 9,454,207 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1208,846,152 - 9,456,443 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl209,192,061 - 9,456,443 (+)Ensemblpanpan1.1panPan2
PLCB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12412,750,631 - 13,169,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2412,752,083 - 13,169,745 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2412,575,552 - 12,993,940 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02413,157,425 - 13,576,878 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2413,157,425 - 13,576,868 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12412,769,385 - 13,187,876 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02412,868,981 - 13,288,064 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02413,206,767 - 13,626,337 (-)NCBIUU_Cfam_GSD_1.0
Plcb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640161,560,396 - 161,921,708 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364859,991,299 - 10,353,123 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364859,991,731 - 10,353,231 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1717,916,110 - 18,402,532 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11717,915,984 - 18,402,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21720,428,956 - 20,770,454 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCB4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,650,604 - 29,059,435 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,650,421 - 28,915,290 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607115,510,020 - 15,919,543 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcb4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474110,277,805 - 10,430,327 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474110,047,899 - 10,435,088 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Plcb4
2178 total Variants

Predicted Target Of
Summary Value
Count of predictions:626
Count of miRNA genes:187
Interacting mature miRNAs:226
Transcripts:ENSRNOT00000042853, ENSRNOT00000045393, ENSRNOT00000049855
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)384091273129091273Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat

1 to 10 of 29 rows
D3Wox21  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23123,321,035 - 123,321,202 (+)MAPPERmRatBN7.2
Rnor_6.03128,970,363 - 128,970,529NCBIRnor6.0
Rnor_5.03135,457,891 - 135,458,057UniSTSRnor5.0
RGSC_v3.43124,076,024 - 124,076,190UniSTSRGSC3.4
Celera3122,060,803 - 122,060,969UniSTS
Cytogenetic Map3q36UniSTS
D3Rat112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23123,217,730 - 123,217,913 (+)MAPPERmRatBN7.2
Rnor_6.03128,867,047 - 128,867,229NCBIRnor6.0
Rnor_5.03135,354,182 - 135,354,364UniSTSRnor5.0
RGSC_v3.43123,971,719 - 123,971,902RGDRGSC3.4
RGSC_v3.43123,971,720 - 123,971,902UniSTSRGSC3.4
RGSC_v3.13123,877,293 - 123,877,475RGD
Celera3121,956,650 - 121,956,832UniSTS
RH 3.4 Map31081.6RGD
RH 3.4 Map31081.6UniSTS
RH 2.0 Map3724.8RGD
SHRSP x BN Map360.7499RGD
Cytogenetic Map3q36UniSTS
D3Rat157  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83143,520,350 - 143,520,503 (+)Marker Load Pipeline
mRatBN7.23123,067,607 - 123,067,760 (+)MAPPERmRatBN7.2
Rnor_6.03128,716,357 - 128,716,509NCBIRnor6.0
Rnor_5.03135,204,992 - 135,205,144UniSTSRnor5.0
RGSC_v3.43123,822,201 - 123,822,354RGDRGSC3.4
RGSC_v3.43123,822,202 - 123,822,354UniSTSRGSC3.4
RGSC_v3.13123,727,775 - 123,727,927RGD
Celera3121,808,597 - 121,808,709UniSTS
RH 3.4 Map31079.6RGD
RH 3.4 Map31079.6UniSTS
RH 2.0 Map3721.1RGD
SHRSP x BN Map360.7899RGD
FHH x ACI Map376.92RGD
Cytogenetic Map3q36UniSTS
D3Rat255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23122,980,747 - 122,980,996 (+)MAPPERmRatBN7.2
Rnor_6.03128,628,848 - 128,629,098NCBIRnor6.0
Rnor_5.03135,117,504 - 135,117,754UniSTSRnor5.0
RGSC_v3.43123,734,009 - 123,734,258RGDRGSC3.4
RGSC_v3.43123,734,008 - 123,734,258UniSTSRGSC3.4
RGSC_v3.13123,639,335 - 123,639,846RGD
Celera3121,722,146 - 121,722,386UniSTS
SHRSP x BN Map359.6699RGD
SHRSP x BN Map359.6699UniSTS
Cytogenetic Map3q36UniSTS
RH143113  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83143,690,824 - 143,690,950 (+)Marker Load Pipeline
mRatBN7.23123,238,090 - 123,238,217 (+)MAPPERmRatBN7.2
Rnor_6.03128,887,410 - 128,887,536NCBIRnor6.0
Rnor_5.03135,374,545 - 135,374,671UniSTSRnor5.0
RGSC_v3.43123,992,083 - 123,992,209UniSTSRGSC3.4
Celera3121,977,081 - 121,977,207UniSTS
RH 3.4 Map31084.4UniSTS
Cytogenetic Map3q36UniSTS
AW534127  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83143,591,979 - 143,592,128 (+)Marker Load Pipeline
mRatBN7.23123,139,242 - 123,139,391 (+)MAPPERmRatBN7.2
Rnor_6.03128,788,971 - 128,789,119NCBIRnor6.0
Rnor_5.03135,276,034 - 135,276,182UniSTSRnor5.0
RGSC_v3.43123,893,184 - 123,893,332UniSTSRGSC3.4
Celera3121,878,575 - 121,878,723UniSTS
RH 3.4 Map31081.6UniSTS
Cytogenetic Map3q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 30 of 42 rows
RefSeq Transcripts NM_001431415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 42 rows

Ensembl Acc Id: ENSRNOT00000042853   ⟹   ENSRNOP00000048553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3123,107,067 - 123,322,377 (+)Ensembl
Rnor_6.0 Ensembl3128,756,799 - 128,971,704 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000045393   ⟹   ENSRNOP00000045972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3123,178,791 - 123,322,392 (+)Ensembl
Rnor_6.0 Ensembl3128,828,331 - 128,971,746 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000049855   ⟹   ENSRNOP00000048775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3123,107,067 - 123,321,123 (+)Ensembl
Rnor_6.0 Ensembl3128,756,799 - 128,970,450 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095786   ⟹   ENSRNOP00000091621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3123,107,067 - 123,322,377 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097572   ⟹   ENSRNOP00000087693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3122,953,196 - 123,320,907 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105709   ⟹   ENSRNOP00000076875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3123,040,696 - 123,322,383 (+)Ensembl
RefSeq Acc Id: NM_024353   ⟹   NP_077329
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,973 - 143,775,124 (+)NCBI
mRatBN7.23122,953,220 - 123,322,393 (+)NCBI
Rnor_6.03128,601,330 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
RGSC_v3.43123,706,313 - 124,077,381 (+)RGD
Celera3121,694,557 - 122,062,160 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235083   ⟹   XP_006235145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
Rnor_6.03128,601,284 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235085   ⟹   XP_006235147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,782 - 143,775,129 (+)NCBI
mRatBN7.23122,952,965 - 123,320,907 (+)NCBI
Rnor_6.03128,601,163 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235088   ⟹   XP_006235150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,515,131 - 143,775,129 (+)NCBI
mRatBN7.23123,060,160 - 123,320,907 (+)NCBI
Rnor_6.03128,711,100 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235094   ⟹   XP_006235156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
mRatBN7.23122,953,307 - 123,321,152 (+)NCBI
Rnor_6.03128,601,284 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104317   ⟹   XP_038960245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104319   ⟹   XP_038960247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,523,410 - 143,775,129 (+)NCBI
mRatBN7.23123,070,667 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104320   ⟹   XP_038960248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,479,865 - 143,775,129 (+)NCBI
mRatBN7.23123,027,100 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104321   ⟹   XP_038960249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,934 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104322   ⟹   XP_038960250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,035 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104323   ⟹   XP_038960251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,934 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104324   ⟹   XP_038960252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,515,131 - 143,775,129 (+)NCBI
mRatBN7.23123,060,160 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104325   ⟹   XP_038960253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,786 - 143,775,129 (+)NCBI
mRatBN7.23122,952,965 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104328   ⟹   XP_038960256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,699,917 - 143,775,129 (+)NCBI
mRatBN7.23123,247,184 - 123,322,522 (+)NCBI
RefSeq Acc Id: XM_063283129   ⟹   XP_063139199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,721 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283130   ⟹   XP_063139200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,523,410 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283131   ⟹   XP_063139201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,782 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283132   ⟹   XP_063139202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,721 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283133   ⟹   XP_063139203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,515,131 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283134   ⟹   XP_063139204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,932 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283135   ⟹   XP_063139205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283136   ⟹   XP_063139206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
1 to 30 of 40 rows
Protein RefSeqs NP_001418344 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418345 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418346 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418347 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418348 (Get FASTA)   NCBI Sequence Viewer  
  NP_077329 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235145 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235147 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235150 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235156 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960245 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960247 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960248 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960249 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960251 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960252 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960253 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960256 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139199 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139200 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139201 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139202 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139203 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139204 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139205 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139206 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC24984 (Get FASTA)   NCBI Sequence Viewer  
  AAC98145 (Get FASTA)   NCBI Sequence Viewer  
  AAD10403 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 40 rows
1 to 5 of 28 rows
1 to 5 of 28 rows
RefSeq Acc Id: NP_077329   ⟸   NM_024353
- UniProtKB: Q9Z0G6 (UniProtKB/Swiss-Prot),   Q9QW07 (UniProtKB/Swiss-Prot),   O88356 (UniProtKB/Swiss-Prot),   F1LNK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235147   ⟸   XM_006235085
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235145   ⟸   XM_006235083
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006235156   ⟸   XM_006235094
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006235150   ⟸   XM_006235088
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
- Sequence:
C2   PI-PLC X-box   PI-PLC Y-box

Name Modeler Protein Id AA Range Protein Structure
AF-Q9QW07-F1-model_v2 AlphaFold Q9QW07 1-1175 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 68 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-47732 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
  PWY-8052 BioCyc
Ensembl Genes ENSRNOG00000033119 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000042853 ENTREZGENE
  ENSRNOT00000045393 ENTREZGENE
  ENSRNOT00000097572 ENTREZGENE
  ENSRNOT00000105709 ENTREZGENE
Gene3D-CATH 1.20.1230.10 UniProtKB/Swiss-Prot
  2.30.29.240 UniProtKB/Swiss-Prot
  2.60.40.150 UniProtKB/Swiss-Prot
  3.20.20.190 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  PI-PLC_fam UniProtKB/Swiss-Prot
  PLC-beta UniProtKB/Swiss-Prot
  PLC-beta_C UniProtKB/Swiss-Prot
  PLC-beta_C_sf UniProtKB/Swiss-Prot
  PLC-beta_PH UniProtKB/Swiss-Prot
  PLC-like_Pdiesterase_TIM-brl UniProtKB/Swiss-Prot
  PLCB1-4-like_EFh UniProtKB/Swiss-Prot
  PLipase_C_PInositol-sp_X_dom UniProtKB/Swiss-Prot
  PLipase_C_Pinositol-sp_Y UniProtKB/Swiss-Prot
KEGG Report rno:25031 UniProtKB/Swiss-Prot
NCBI Gene 25031 ENTREZGENE
PANTHER 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 UniProtKB/Swiss-Prot
  PTHR10336 UniProtKB/Swiss-Prot
Pfam PF00168 UniProtKB/Swiss-Prot
  PH_14 UniProtKB/Swiss-Prot
  PI-PLC-X UniProtKB/Swiss-Prot
  PI-PLC-Y UniProtKB/Swiss-Prot
  PLC-beta_C UniProtKB/Swiss-Prot
  PLCB1-4-like_EFh UniProtKB/Swiss-Prot
PhenoGen Plcb4 PhenoGen
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Plcb4  Phospholipase C , beta4      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_homology has 50% amino acid identity with D. melanogastar norpA 633574