No known orthologs.
Symbol:
Ppial4d
Name:
peptidylprolyl isomerase A (cyclophilin A)-like 4D
RGD ID:
2321083
Description:
Predicted to enable heparan sulfate binding activity; integrin binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in several processes, including cell adhesion molecule production; regulation of intracellular signal transduction; and regulation of protein modification process. Predicted to be located in cytosol; extracellular region; and nucleus. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
LOC100360977; peptidyl-prolyl cis-trans isomerase A; TRIMCyp-like
RGD Orthologs
Alliance Orthologs
More Info
homologs ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 14 21,361,379 - 21,362,147 (+) NCBI GRCr8 mRatBN7.2 14 21,006,522 - 21,007,284 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 14 21,006,538 - 21,007,310 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 14 22,706,906 - 22,707,648 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 14 22,706,901 - 22,707,668 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 14 22,609,711 - 22,610,447 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 14 22,612,891 - 22,613,385 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Cytogenetic Map 14 p21 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
.
1300114 Srn2 Serum renin concentration QTL 2 3.27 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 14 3813074 21217635 Rat 1581500 Renag1 Renal agenesis QTL 1 kidney development trait (VT:0000527) percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940) 14 8170668 68298175 Rat 731183 Pia20 Pristane induced arthritis QTL 20 3.55 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 14 9088978 39057237 Rat 631212 Bw5 Body weight QTL5 5.43 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 14 11030812 30320092 Rat 2302277 Gluco38 Glucose level QTL 38 5.8 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 14 11030622 28035204 Rat 10755459 Coatc15 Coat color QTL 15 0.01681 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 14 19836944 64836944 Rat 1331740 Bw26 Body weight QTL 26 3.028 body mass (VT:0001259) body weight (CMO:0000012) 14 3813074 30767156 Rat 619619 Rf4 Renal disease susceptibility QTL 4 4.1 0.002 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 14 1 32754612 Rat 1358296 Ael3 Aortic elastin QTL 3 3.7 0.00051 aorta elastin amount (VT:0003905) aortic elastin 14 8267090 53267090 Rat 71117 Niddm17 Non-insulin dependent diabetes mellitus QTL 17 2.35 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 14 17593761 42336881 Rat 61420 Pia6 Pristane induced arthritis QTL 6 4.9 joint integrity trait (VT:0010548) arthritic paw count (CMO:0001460) 14 18631345 42337007 Rat 70195 Mcs8 Mammary carcinoma susceptibility QTL 8 4.28 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 14 3813074 24531477 Rat 2300183 Bmd60 Bone mineral density QTL 60 5.7 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 14 1 26541967 Rat 631839 Niddm37 Non-insulin dependent diabetes mellitus QTL 37 3.37 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 14 11030622 95876975 Rat 2313397 Coatc1 Coat color QTL1 coat/hair pigmentation trait (VT:0010463) coat/hair color measurement (CMO:0001808) 14 18541332 63541332 Rat 631262 Tcas4 Tongue tumor susceptibility QTL 4 7.29 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950) 14 17622561 42337007 Rat 634352 Apr6 Acute phase response QTL 6 3.7 blood interleukin-6 amount (VT:0008595) plasma interleukin-6 level (CMO:0001927) 14 1 41131407 Rat 2300159 Bmd61 Bone mineral density QTL 61 5.3 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 14 1 26541967 Rat 2302045 Pia39 Pristane induced arthritis QTL 39 4.9 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G2a level (CMO:0002116) 14 8267090 53267090 Rat 1300140 Srn3 Serum renin concentration QTL 3 3.19 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 14 14875168 30883947 Rat
UniSTS:265677
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 14 21,006,765 - 21,007,058 (+) MAPPER mRatBN7.2 mRatBN7.2 4 41,829,100 - 41,829,392 (+) MAPPER mRatBN7.2 Rnor_6.0 14 22,707,130 - 22,707,422 NCBI Rnor6.0 Rnor_5.0 14 22,609,939 - 22,610,231 UniSTS Rnor5.0 RGSC_v3.4 14 22,613,076 - 22,613,368 UniSTS RGSC3.4 Cytogenetic Map 14 q21 UniSTS
Ppia
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 14 21,006,634 - 21,006,784 (+) MAPPER mRatBN7.2 Rnor_6.0 14 22,706,999 - 22,707,148 NCBI Rnor6.0 Rnor_5.0 14 22,609,808 - 22,609,957 UniSTS Rnor5.0 Cytogenetic Map 14 q21 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
12
12
62
68
60
36
12
36
12
116
48
38
20
38
24
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000088798 ⟹ ENSRNOP00000071404
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 14 22,706,901 - 22,707,668 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000106407 ⟹ ENSRNOP00000089529
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 14 21,006,538 - 21,007,310 (+) Ensembl
RefSeq Acc Id:
XM_006250801 ⟹ XP_006250863
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 14 21,361,379 - 21,362,147 (+) NCBI mRatBN7.2 14 21,006,522 - 21,007,284 (+) NCBI Rnor_6.0 14 22,706,906 - 22,707,648 (+) NCBI Rnor_5.0 14 22,609,711 - 22,610,447 (+) NCBI
Sequence:
TGCAGACGCCGCTGTCTCTTTTCGCCGCTTGCTGCAGACATGGTCAACCCCACCGTGTTCTTCGACATCACGGCTGATGGCGAGCCCTTGGGTCGCGTCTGCTTCGAGCTGTTTGCAGACAAAGTGCC AAAGACAGCAGAAAACTTTCGTGCTCTGAGCACTGGGGAGAAAGGATTTGGCTATAAGGGTTCCTCCTTTCACAGAATTATTCCAGGATTCATGTGCCAGGGTGGTGACTTCACACGCCATAATGGCA CTGGTGGCAAGTCCATCTACGGAGAGAAATTTGAGGATGAGAACTTCATCCTGAAGCATACAGGTCCTGGCATCTTGTCCATGGCAAATGCTGGACCAAACACAAATGGTTCCCAGTTTTTTATCTGC ACTGCCAAGACTGAGTGGCTGGATGGCAAGCATGTGGTCTTTGGGAAGGTGAAAGAAGGCATGAGCATTGTGGAAGCCATGGAGCGTTTTGGGTCCAGGAATGGCAAGACCAGCAAGAAGATCACCAT CTCCGACTGTGGACAACTCTAATTTCTTTGACTTGCGGGCATTTTACCCATCAAACCATTCCTTCTGTAGCTCAGGAGAGCACCCCCACCCCATCTGCTCGCAATACCCTGTAATCTCTGCTCTCACT GAAGTTCTTTGGGTTCCATATTTTCCTCATTCCCCTTCAAGTCTAGCAGGATTGCAAAGTTAAGTTTATGATTATGAATAAAAACTAAATGAGAAAAAAAAAA
hide sequence
RefSeq Acc Id:
XP_006250863 ⟸ XM_006250801
- UniProtKB:
P18303 (UniProtKB/Swiss-Prot), Q5BK98 (UniProtKB/Swiss-Prot), P10111 (UniProtKB/Swiss-Prot), A6IKU0 (UniProtKB/TrEMBL), A6IKT9 (UniProtKB/TrEMBL)
- Sequence:
MVNPTVFFDITADGEPLGRVCFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVV FGKVKEGMSIVEAMERFGSRNGKTSKKITISDCGQL
hide sequence
Ensembl Acc Id:
ENSRNOP00000071404 ⟸ ENSRNOT00000088798
Ensembl Acc Id:
ENSRNOP00000089529 ⟸ ENSRNOT00000106407
RGD ID: 13699264
Promoter ID: EPDNEW_R9781
Type: single initiation site
Name: Ppial4d_1
Description: peptidylprolyl isomerase A -like 4D
SO ACC ID: SO:0000170
Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ )
Experiment Methods: Single-end sequencing.
Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 14 22,706,901 - 22,706,961 EPDNEW
BioCyc Gene
G2FUF-16096
BioCyc
Ensembl Genes
ENSRNOG00000055068
Ensembl
ENSRNOG00000068764
Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript
ENSRNOT00000106407.1
UniProtKB/Swiss-Prot
Gene3D-CATH
2.40.100.10
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro
Cyclophilin-like_dom_sf
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Cyclophilin-type_PPIase
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Cyclophilin-type_PPIase_CS
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Cyclophilin-type_PPIase_dom
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report
rno:100360977
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
rno:25518
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene
100360977
ENTREZGENE
PANTHER
PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam
Pro_isomerase
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen
Ppial4d
PhenoGen
PIRSF
Peptidylpro_ismrse
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS
CSAPPISMRASE
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE
CSA_PPIASE_1
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
CSA_PPIASE_2
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx
ENSRNOG00000055068
RatGTEx
ENSRNOG00000068764
RatGTEx
Superfamily-SCOP
Cyclophilin-like
UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt
A6IKT9
ENTREZGENE, UniProtKB/TrEMBL
A6IKU0
ENTREZGENE, UniProtKB/TrEMBL
P10111
ENTREZGENE
P18303
ENTREZGENE
PPIA_RAT
UniProtKB/Swiss-Prot
Q5BK98
ENTREZGENE
UniProt Secondary
P18303
UniProtKB/Swiss-Prot
Q5BK98
UniProtKB/Swiss-Prot
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2022-06-02
Ppial4d
peptidylprolyl isomerase A (cyclophilin A)-like 4D
Ppial4d
peptidylprolyl isomerase A (cyclophilin A)-like 4D
Data merged from RGD:149736382
737654
PROVISIONAL
2021-08-09
Ppial4d
peptidylprolyl isomerase A (cyclophilin A)-like 4D
Symbol and Name status set to provisional
45752
PROVISIONAL
2015-06-09
Ppial4d
peptidylprolyl isomerase A (cyclophilin A)-like 4D
LOC100360977
TRIMCyp-like
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2010-05-05
LOC100360977
TRIMCyp-like
Symbol and Name status set to provisional
70820
PROVISIONAL