Symbol:
Cox6b1
Name:
cytochrome c oxidase subunit 6B1
RGD ID:
1584097
Description:
Predicted to be involved in substantia nigra development. Predicted to be located in mitochondrial membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 7. Orthologous to human COX6B1 (cytochrome c oxidase subunit 6B1); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol; ampicillin.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
COX VIb-1; Cox6b; cytochrome c oxidase subunit VIb; cytochrome c oxidase subunit VIb polypeptide 1; cytochrome c oxidase, subunit VIb polypeptide 1; LOC688869; similar to cytochrome c oxidase, subunit VIb polypeptide 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Related Pseudogenes:
Cox6b1-ps1
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 95,002,513 - 95,011,516 (-) NCBI GRCr8 mRatBN7.2 1 85,875,080 - 85,884,081 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 85,875,109 - 85,884,001 (-) Ensembl mRatBN7.2 Ensembl mRatBN7.2 Ensembl 2 196,169,217 - 196,184,807 (+) Ensembl mRatBN7.2 Ensembl mRatBN7.2 Ensembl 5 69,646,379 - 69,646,672 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 91,291,647 - 91,298,770 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 99,757,820 - 99,764,941 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 93,049,937 - 93,057,059 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 89,075,987 - 89,084,834 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 89,075,975 - 89,084,859 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 211,337,271 - 211,337,531 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 90,230,830 - 90,240,520 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 85,669,891 - 85,677,195 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 1 80,246,804 - 80,254,197 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Disease Annotations - ClinVar
Imported Disease Annotations - OMIM
Only show annotations with direct experimental evidence (0 objects hidden)
Cox6b1 Rat (+)-dexrazoxane increases expression ISO RGD:1614989 6480464 Dexrazoxane results in increased expression of COX6B1 mRNA CTD PMID:26873546 Cox6b1 Rat (1->4)-beta-D-glucan multiple interactions ISO RGD:1614989 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of COX6B1 mRNA CTD PMID:36331819 Cox6b1 Rat 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:1614989 6480464 o,p'-DDT results in increased expression of COX6B1 mRNA CTD PMID:24096037 Cox6b1 Rat 1,2-dimethylhydrazine multiple interactions ISO RGD:1614989 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX6B1 mRNA CTD PMID:22206623 Cox6b1 Rat 17alpha-ethynylestradiol increases expression ISO RGD:1614989 6480464 Ethinyl Estradiol results in increased expression of COX6B1 mRNA CTD PMID:24096037 Cox6b1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1614989 6480464 Tetrachlorodibenzodioxin results in decreased expression of COX6B1 mRNA CTD PMID:19770486 Cox6b1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1614989 6480464 Tetrachlorodibenzodioxin results in increased expression of COX6B1 mRNA CTD PMID:20399798 Cox6b1 Rat 2,4-diaminobutyric acid multiple interactions ISO RGD:1343660 6480464 [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of COX6B1 mRNA CTD PMID:28634653 Cox6b1 Rat 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1,2-dithiol-3-thione results in increased expression of COX6B1 mRNA CTD PMID:19162173 Cox6b1 Rat 4,4'-sulfonyldiphenol increases expression ISO RGD:1614989 6480464 bisphenol S results in increased expression of COX6B1 mRNA CTD PMID:39298647 Cox6b1 Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 Cox6b1 Rat 5-Hydroxythalidomide affects binding ISO RGD:1614989 6480464 5-hydroxythalidomide binds to COX6B1 protein CTD PMID:27464947 Cox6b1 Rat 5-Hydroxythalidomide affects binding ISO RGD:1343660 6480464 5-hydroxythalidomide binds to COX6B1 protein CTD PMID:27464947 Cox6b1 Rat ampicillin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in more ... CTD PMID:30545405 Cox6b1 Rat arsane affects methylation ISO RGD:1343660 6480464 Arsenic affects the methylation of COX6B1 gene CTD PMID:25304211 Cox6b1 Rat arsane multiple interactions ISO RGD:1343660 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of COX6B1 more ... CTD PMID:39836092 Cox6b1 Rat arsenic atom affects methylation ISO RGD:1343660 6480464 Arsenic affects the methylation of COX6B1 gene CTD PMID:25304211 Cox6b1 Rat arsenic atom multiple interactions ISO RGD:1343660 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of COX6B1 more ... CTD PMID:39836092 Cox6b1 Rat arsenite(3-) multiple interactions ISO RGD:1343660 6480464 arsenite promotes the reaction [G3BP1 protein binds to COX6B1 mRNA] CTD PMID:32406909 Cox6b1 Rat astaxanthin multiple interactions ISO RGD:1614989 6480464 astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA] CTD PMID:16964424 Cox6b1 Rat azoxystrobin increases expression ISO RGD:1343660 6480464 azoxystrobin results in increased expression of COX6B1 mRNA CTD PMID:33512557 Cox6b1 Rat benzo[a]pyrene decreases expression ISO RGD:1343660 6480464 Benzo(a)pyrene results in decreased expression of COX6B1 protein CTD PMID:33278487 Cox6b1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1614989 6480464 Diethylhexyl Phthalate results in decreased expression of COX6B1 mRNA CTD PMID:35550907 Cox6b1 Rat bis(2-ethylhexyl) phthalate increases expression ISO RGD:1614989 6480464 Diethylhexyl Phthalate results in increased expression of COX6B1 mRNA CTD PMID:33754040 Cox6b1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of COX6B1 mRNA CTD PMID:25181051|PMID:30816183 Cox6b1 Rat bisphenol A decreases expression ISO RGD:1614989 6480464 bisphenol A results in decreased expression of COX6B1 mRNA CTD PMID:35598803 Cox6b1 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 Cox6b1 Rat bisphenol A increases expression ISO RGD:1343660 6480464 bisphenol A results in increased expression of COX6B1 protein CTD PMID:37567409 Cox6b1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of COX6B1 mRNA CTD PMID:32145629 Cox6b1 Rat bisphenol A decreases expression ISO RGD:1343660 6480464 bisphenol A results in decreased expression of COX6B1 mRNA CTD PMID:38568856 Cox6b1 Rat bisphenol A affects expression ISO RGD:1343660 6480464 bisphenol A affects the expression of COX6B1 mRNA CTD PMID:30903817 Cox6b1 Rat bisphenol F decreases expression ISO RGD:1614989 6480464 bisphenol F results in decreased expression of COX6B1 mRNA CTD PMID:38685157 Cox6b1 Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 Cox6b1 Rat Brodifacoum decreases expression EXP 6480464 bromfenacoum results in decreased expression of COX6B1 protein CTD PMID:28903499 Cox6b1 Rat cadmium dichloride increases expression ISO RGD:1343660 6480464 Cadmium Chloride results in increased expression of COX6B1 mRNA CTD PMID:38568856 Cox6b1 Rat captan increases expression ISO RGD:1614989 6480464 Captan results in increased expression of COX6B1 mRNA CTD PMID:31558096 Cox6b1 Rat CGP 52608 multiple interactions ISO RGD:1343660 6480464 CGP 52608 promotes the reaction [RORA protein binds to COX6B1 gene] CTD PMID:28238834 Cox6b1 Rat chloropicrin affects expression ISO RGD:1343660 6480464 chloropicrin affects the expression of COX6B1 mRNA CTD PMID:26352163 Cox6b1 Rat cisplatin multiple interactions ISO RGD:1343660 6480464 [Quercetin co-treated with Cisplatin] results in increased expression of COX6B1 mRNA CTD PMID:24999622 Cox6b1 Rat copper atom affects expression EXP 6480464 Copper affects the expression of COX6B1 protein CTD PMID:17182794 Cox6b1 Rat copper(0) affects expression EXP 6480464 Copper affects the expression of COX6B1 protein CTD PMID:17182794 Cox6b1 Rat corosolic acid decreases expression ISO RGD:1343660 6480464 corosolic acid results in decreased expression of COX6B1 mRNA CTD PMID:37939859 Cox6b1 Rat cyclosporin A decreases expression ISO RGD:1614989 6480464 Cyclosporine results in decreased expression of COX6B1 mRNA CTD PMID:19770486 Cox6b1 Rat cyclosporin A decreases expression ISO RGD:1343660 6480464 Cyclosporine results in decreased expression of COX6B1 mRNA CTD PMID:20106945 Cox6b1 Rat doxorubicin increases expression ISO RGD:1614989 6480464 Doxorubicin results in increased expression of COX6B1 mRNA CTD PMID:26873546 Cox6b1 Rat doxorubicin increases expression ISO RGD:1343660 6480464 Doxorubicin results in increased expression of COX6B1 mRNA CTD PMID:29803840 Cox6b1 Rat epoxiconazole increases expression ISO RGD:1614989 6480464 epoxiconazole results in increased expression of COX6B1 mRNA CTD PMID:35436446 Cox6b1 Rat ethanol multiple interactions ISO RGD:1614989 6480464 Ethanol affects the expression of and affects the splicing of COX6B1 mRNA CTD PMID:30319688 Cox6b1 Rat folic acid multiple interactions ISO RGD:1614989 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COX6B1 mRNA CTD PMID:22206623 Cox6b1 Rat folpet increases expression ISO RGD:1614989 6480464 folpet results in increased expression of COX6B1 mRNA CTD PMID:31558096 Cox6b1 Rat gentamycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in more ... CTD PMID:30545405 Cox6b1 Rat hydralazine multiple interactions ISO RGD:1343660 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of COX6B1 mRNA CTD PMID:17183730 Cox6b1 Rat isoniazide affects expression ISO RGD:1614989 6480464 Isoniazid affects the expression of COX6B1 mRNA CTD PMID:24848797 Cox6b1 Rat ivermectin decreases expression ISO RGD:1343660 6480464 Ivermectin results in decreased expression of COX6B1 protein CTD PMID:32959892 Cox6b1 Rat maneb multiple interactions ISO RGD:1614989 6480464 [Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA; Melatonin inhibits the reaction more ... CTD PMID:23963992 Cox6b1 Rat manganese atom multiple interactions ISO RGD:1343660 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of COX6B1 more ... CTD PMID:39836092 Cox6b1 Rat manganese(0) multiple interactions ISO RGD:1343660 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of COX6B1 more ... CTD PMID:39836092 Cox6b1 Rat manganese(II) chloride multiple interactions ISO RGD:1343660 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of COX6B1 more ... CTD PMID:39836092 Cox6b1 Rat melatonin multiple interactions ISO RGD:1614989 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA] CTD PMID:23963992 Cox6b1 Rat methidathion increases expression ISO RGD:1614989 6480464 methidathion results in increased expression of COX6B1 mRNA CTD PMID:34813904 Cox6b1 Rat methotrexate decreases expression ISO RGD:1343660 6480464 Methotrexate results in decreased expression of COX6B1 mRNA CTD PMID:17400583 Cox6b1 Rat methylparaben decreases expression ISO RGD:1343660 6480464 methylparaben results in decreased expression of COX6B1 mRNA CTD PMID:38568856 Cox6b1 Rat metronidazole multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in more ... CTD PMID:30545405 Cox6b1 Rat neomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in more ... CTD PMID:30545405 Cox6b1 Rat nitrates multiple interactions ISO RGD:1614989 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of COX6B1 more ... CTD PMID:35964746 Cox6b1 Rat paracetamol increases expression ISO RGD:1343660 6480464 Acetaminophen results in increased expression of COX6B1 mRNA CTD PMID:25704631 Cox6b1 Rat paracetamol decreases expression ISO RGD:1343660 6480464 Acetaminophen results in decreased expression of COX6B1 mRNA CTD PMID:29067470 Cox6b1 Rat paracetamol affects expression ISO RGD:1614989 6480464 Acetaminophen affects the expression of COX6B1 mRNA CTD PMID:17562736 Cox6b1 Rat paracetamol increases expression ISO RGD:1614989 6480464 Acetaminophen results in increased expression of COX6B1 protein CTD PMID:21329376 Cox6b1 Rat paraquat multiple interactions ISO RGD:1614989 6480464 [Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA; Melatonin inhibits the reaction more ... CTD PMID:23963992 Cox6b1 Rat perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1614989 6480464 perfluorooctane sulfonic acid results in decreased expression of COX6B1 mRNA CTD PMID:20936131 Cox6b1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1614989 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of COX6B1 mRNA; PPARA protein more ... CTD PMID:20936131|PMID:36331819 Cox6b1 Rat perfluorooctanoic acid decreases expression ISO RGD:1343660 6480464 perfluorooctanoic acid results in decreased expression of COX6B1 protein CTD PMID:26879310 Cox6b1 Rat picoxystrobin increases expression ISO RGD:1343660 6480464 picoxystrobin results in increased expression of COX6B1 mRNA CTD PMID:33512557 Cox6b1 Rat pirinixic acid increases expression ISO RGD:1614989 6480464 pirinixic acid results in increased expression of COX6B1 mRNA CTD PMID:23811191 Cox6b1 Rat progesterone decreases expression ISO RGD:1614989 6480464 Progesterone results in decreased expression of COX6B1 mRNA CTD PMID:19693291 Cox6b1 Rat pyrimidifen increases expression ISO RGD:1343660 6480464 pyrimidifen results in increased expression of COX6B1 mRNA CTD PMID:33512557 Cox6b1 Rat pyrogallol decreases expression ISO RGD:1614989 6480464 Pyrogallol results in decreased expression of COX6B1 mRNA CTD PMID:20362636 Cox6b1 Rat quercetin multiple interactions ISO RGD:1343660 6480464 [Quercetin co-treated with Cisplatin] results in increased expression of COX6B1 mRNA CTD PMID:24999622 Cox6b1 Rat resveratrol increases expression ISO RGD:1614989 6480464 resveratrol results in increased expression of COX6B1 mRNA CTD PMID:22610192 Cox6b1 Rat rotenone increases expression ISO RGD:1343660 6480464 Rotenone results in increased expression of COX6B1 mRNA CTD PMID:33512557 Cox6b1 Rat sodium arsenite increases expression ISO RGD:1343660 6480464 sodium arsenite results in increased expression of COX6B1 mRNA CTD PMID:34032870 Cox6b1 Rat sodium arsenite multiple interactions ISO RGD:1343660 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of COX6B1 more ... CTD PMID:39836092 Cox6b1 Rat testosterone increases expression ISO RGD:1614989 6480464 Testosterone results in increased expression of COX6B1 mRNA CTD PMID:19693291 Cox6b1 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of COX6B1 mRNA CTD PMID:31150632 Cox6b1 Rat thapsigargin decreases expression ISO RGD:1343660 6480464 Thapsigargin results in decreased expression of COX6B1 mRNA CTD PMID:22378314 Cox6b1 Rat titanium dioxide decreases expression ISO RGD:1614989 6480464 titanium dioxide analog results in decreased expression of COX6B1 mRNA CTD PMID:25111187 Cox6b1 Rat toluene affects expression EXP 6480464 Toluene affects the expression of COX6B1 mRNA CTD PMID:21827849 Cox6b1 Rat triphenyl phosphate affects expression ISO RGD:1343660 6480464 triphenyl phosphate affects the expression of COX6B1 mRNA CTD PMID:37042841 Cox6b1 Rat tungsten increases expression ISO RGD:1614989 6480464 Tungsten results in increased expression of COX6B1 mRNA CTD PMID:30912803 Cox6b1 Rat tunicamycin decreases expression ISO RGD:1343660 6480464 Tunicamycin results in decreased expression of COX6B1 mRNA CTD PMID:22378314 Cox6b1 Rat valproic acid multiple interactions ISO RGD:1343660 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of COX6B1 mRNA CTD PMID:17183730 Cox6b1 Rat valproic acid affects expression ISO RGD:1343660 6480464 Valproic Acid affects the expression of COX6B1 mRNA CTD PMID:25979313 Cox6b1 Rat vancomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in more ... CTD PMID:30545405 Cox6b1 Rat vincaleukoblastine affects response to substance ISO RGD:1343660 6480464 COX6B1 protein affects the susceptibility to Vinblastine CTD PMID:16217747
Imported Annotations - KEGG (archival)
(+)-dexrazoxane (ISO) (1->4)-beta-D-glucan (ISO) 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (ISO) 1,2-dimethylhydrazine (ISO) 17alpha-ethynylestradiol (ISO) 2,3,7,8-tetrachlorodibenzodioxine (ISO) 2,4-diaminobutyric acid (ISO) 3H-1,2-dithiole-3-thione (EXP) 4,4'-sulfonyldiphenol (EXP,ISO) 5-Hydroxythalidomide (ISO) ampicillin (EXP) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) astaxanthin (ISO) azoxystrobin (ISO) benzo[a]pyrene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (EXP,ISO) Brodifacoum (EXP) cadmium dichloride (ISO) captan (ISO) CGP 52608 (ISO) chloropicrin (ISO) cisplatin (ISO) copper atom (EXP) copper(0) (EXP) corosolic acid (ISO) cyclosporin A (ISO) doxorubicin (ISO) epoxiconazole (ISO) ethanol (ISO) folic acid (ISO) folpet (ISO) gentamycin (EXP) hydralazine (ISO) isoniazide (ISO) ivermectin (ISO) maneb (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) melatonin (ISO) methidathion (ISO) methotrexate (ISO) methylparaben (ISO) metronidazole (EXP) neomycin (EXP) nitrates (ISO) paracetamol (ISO) paraquat (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (ISO) picoxystrobin (ISO) pirinixic acid (ISO) progesterone (ISO) pyrimidifen (ISO) pyrogallol (ISO) quercetin (ISO) resveratrol (ISO) rotenone (ISO) sodium arsenite (ISO) testosterone (ISO) tetrachloromethane (EXP) thapsigargin (ISO) titanium dioxide (ISO) toluene (EXP) triphenyl phosphate (ISO) tungsten (ISO) tunicamycin (ISO) valproic acid (ISO) vancomycin (EXP) vincaleukoblastine (ISO)
References
Additional References at PubMed
Genomics
Comparative Map Data
Cox6b1 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 95,002,513 - 95,011,516 (-) NCBI GRCr8 mRatBN7.2 1 85,875,080 - 85,884,081 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 85,875,109 - 85,884,001 (-) Ensembl mRatBN7.2 Ensembl mRatBN7.2 Ensembl 2 196,169,217 - 196,184,807 (+) Ensembl mRatBN7.2 Ensembl mRatBN7.2 Ensembl 5 69,646,379 - 69,646,672 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 91,291,647 - 91,298,770 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 99,757,820 - 99,764,941 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 93,049,937 - 93,057,059 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 89,075,987 - 89,084,834 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 89,075,975 - 89,084,859 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 211,337,271 - 211,337,531 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 90,230,830 - 90,240,520 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 85,669,891 - 85,677,195 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 1 80,246,804 - 80,254,197 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
COX6B1 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 35,648,323 - 35,658,782 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 35,648,323 - 35,658,782 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 36,139,225 - 36,149,684 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 40,830,995 - 40,841,524 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 40,830,994 - 40,841,523 NCBI Celera 19 32,852,598 - 32,863,159 (+) NCBI Celera Cytogenetic Map 19 q13.12 NCBI HuRef 19 32,644,378 - 32,654,939 (+) NCBI HuRef CHM1_1 19 36,140,657 - 36,151,217 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 38,193,302 - 38,203,762 (+) NCBI T2T-CHM13v2.0
Cox6b1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 30,316,396 - 30,325,539 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 30,316,286 - 30,325,576 (-) Ensembl GRCm39 Ensembl GRCm38 7 30,616,971 - 30,626,114 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 30,616,861 - 30,626,151 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 31,401,993 - 31,411,170 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 30,325,734 - 30,334,911 (-) NCBI MGSCv36 mm8 MGSCv36 7 22,894,581 - 22,903,778 (-) NCBI MGSCv36 mm8 Celera 7 25,208,771 - 25,217,172 (-) NCBI Celera Cytogenetic Map 7 B1 NCBI cM Map 7 18.84 NCBI
LOC102025227 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955468 2,884,958 - 2,891,988 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955468 2,884,958 - 2,891,952 (-) NCBI ChiLan1.0 ChiLan1.0
LOC100972703 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 41,644,489 - 41,655,044 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 43,627,947 - 43,638,506 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 19 32,578,126 - 32,588,684 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 41,314,020 - 41,324,489 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 19 41,314,020 - 41,324,489 (+) Ensembl panpan1.1 panPan2
LOC612644 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 116,960,851 - 116,969,415 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 116,366,059 - 116,374,616 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 117,564,045 - 117,572,630 (-) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 1 117,127,088 - 117,135,659 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 116,750,997 - 116,759,548 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 117,806,857 - 117,815,447 (-) NCBI UU_Cfam_GSD_1.0
LOC101972214
COX6B Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 45,091,895 - 45,102,669 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 45,091,829 - 45,102,785 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 40,548,689 - 40,559,158 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
LOC103242353
LOC101697786
.
miRNA Target Status (No longer updated)
Predicted Target Of
Count of predictions: 77 Count of miRNA genes: 65 Interacting mature miRNAs: 67 Transcripts: ENSRNOT00000032026 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
QTLs in Region (GRCr8)
2313059 Bss55 Bone structure and strength QTL 55 3.2 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 1 43284731 118944897 Rat 631688 Hcas2 Hepatocarcinoma susceptibility QTL 2 3 0.0001 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 5925874 115540829 Rat 1578649 Bmd8 Bone mineral density QTL 8 4.9 femur mineral mass (VT:0010011) trabecular volumetric bone mineral density (CMO:0001729) 1 49393172 94393172 Rat 1582234 Gluco18 Glucose level QTL 18 3.4 0.0003 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 78479925 123479925 Rat 1358359 Sradr1 Stress Responsive Adrenal Weight QTL 1 4.74 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 1 30882023 123479925 Rat 634314 Niddm44 Non-insulin dependent diabetes mellitus QTL 44 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 49393289 199050459 Rat 1578780 Cm52 Cardiac mass QTL 52 3.3 0.0001 heart mass (VT:0007028) heart wet weight (CMO:0000069) 1 81591954 219808434 Rat 1578654 Bss10 Bone structure and strength QTL 10 4 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 1 49393172 159356837 Rat 1554320 Bmd1 Bone mineral density QTL 1 12.2 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 1 509108 86060548 Rat 2300324 Fetw1 Fetal weight QTL 1 12.1 0.005 fetal growth trait (VT:0004201) fetal body weight (CMO:0002080) 1 85424647 100358001 Rat 2302059 Pia36 Pristane induced arthritis QTL 36 3.8 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 1 43333002 88333002 Rat 1300121 Hrtrt1 Heart rate QTL 1 3.7 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 1 65789093 115540829 Rat 7421628 Bp361 Blood pressure QTL 361 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 66023617 118608521 Rat 631495 Bp96 Blood pressure QTL 96 4.52 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 22340647 102268831 Rat 70225 Bp58 Blood pressure QTL 58 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32356093 162846471 Rat 631512 Scl6 Serum cholesterol level QTL 6 9.6 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 1 72197680 90508767 Rat 2298545 Neuinf8 Neuroinflammation QTL 8 4.6 nervous system integrity trait (VT:0010566) spinal cord beta-2 microglobulin mRNA level (CMO:0002125) 1 57336763 151090257 Rat 2313072 Bss53 Bone structure and strength QTL 53 4.3 0.0001 tibia length (VT:0004357) tibia length (CMO:0000450) 1 43284731 118944897 Rat 10059597 Bp377 Blood pressure QTL 377 3.42 0.025 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32737458 199368955 Rat 2313078 Bss54 Bone structure and strength QTL 54 3.5 0.0001 tibia area (VT:1000281) tibia midshaft cross-sectional area (CMO:0001717) 1 43284731 118944897 Rat 1549903 Bp267 Blood pressure QTL 267 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 77876254 106047988 Rat 2313083 Bmd74 Bone mineral density QTL 74 4 0.0001 tibia mineral mass (VT:1000283) total volumetric bone mineral density (CMO:0001728) 1 82174743 118944897 Rat 2313402 Anxrr24 Anxiety related response QTL 24 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 1 48963584 144267916 Rat 4889494 Scort2 Serum corticosterone level QTL 2 4.2 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 1 80592172 125592172 Rat 61342 Bp27 Blood pressure QTL 27 3.4 0.0006 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 56732668 98773277 Rat 1300172 Bp172 Blood pressure QTL 172 3.56 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 1 32737273 90665040 Rat 61344 Bp29 Blood pressure QTL 29 7.5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 78350581 123350581 Rat 1358192 Ept13 Estrogen-induced pituitary tumorigenesis QTL 13 3.4 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 1 77494165 122494165 Rat 2313094 Bss58 Bone structure and strength QTL 58 3.7 0.0001 tibia strength trait (VT:1000284) tibia total energy absorbed before break (CMO:0001736) 1 43284731 118944897 Rat 6903308 Scl36 Serum cholesterol QTL 36 2 0.0125 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 1 53863041 90532583 Rat 2300164 Bmd44 Bone mineral density QTL 44 5.4 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 1 56949932 101949932 Rat 2313099 Bss56 Bone structure and strength QTL 56 2.4 0.0001 tibia size trait (VT:0100001) tibia midshaft endosteal cross-sectional area (CMO:0001716) 1 43284731 118944897 Rat 2313098 Bmd70 Bone mineral density QTL 70 3.6 0.0001 tibia mineral mass (VT:1000283) compact volumetric bone mineral density (CMO:0001730) 1 43284731 118944897 Rat 738022 Anxrr13 Anxiety related response QTL 13 4.6 0.00039 locomotor behavior trait (VT:0001392) measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514) 1 83547917 128547917 Rat 152025249 Scl82 Serum cholesterol level QTL 82 4.77 blood cholesterol amount (VT:0000180) 1 50343510 99980958 Rat 10054135 Gmadr2 Adrenal mass QTL 2 1.97 0.0129 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 1 77857876 122857876 Rat 7411712 Strs4 Sensitivity to stroke QTL 4 8.7 cerebrum integrity trait (VT:0010549) percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932) 1 78430536 123430536 Rat 2313051 Bss57 Bone structure and strength QTL 57 3.7 0.0001 tibia strength trait (VT:1000284) bone polar moment of inertia (CMO:0001558) 1 43284731 118944897 Rat 61433 Cia2 Collagen induced arthritis QTL 2 5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 1 78430754 91209302 Rat
Markers in Region
Cox6b1
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 196,182,894 - 196,183,120 (+) MAPPER mRatBN7.2 Rnor_6.0 2 211,337,303 - 211,337,528 NCBI Rnor6.0 Rnor_5.0 2 230,807,098 - 230,807,323 UniSTS Rnor5.0 Celera 5 68,513,392 - 68,513,617 UniSTS Celera 2 188,828,786 - 188,829,011 UniSTS Cytogenetic Map 2 q34 UniSTS Cytogenetic Map 1 q21 UniSTS
Expression
RNA-SEQ Expression
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
18
22
98
218
175
173
111
50
111
12
424
194
178
85
118
62
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Sequence
Ensembl Acc Id:
ENSRNOT00000032026 ⟹ ENSRNOP00000030997
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 85,875,109 - 85,884,001 (-) Ensembl Rnor_6.0 Ensembl 1 89,075,975 - 89,084,859 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000045155 ⟹ ENSRNOP00000048723
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 69,646,379 - 69,646,672 (+) Ensembl Rnor_6.0 Ensembl 2 211,337,271 - 211,337,531 (+) Ensembl
RefSeq Acc Id:
NM_001145273 ⟹ NP_001138745
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 95,002,513 - 95,009,852 (-) NCBI mRatBN7.2 1 85,875,080 - 85,882,420 (-) NCBI Rnor_6.0 1 89,075,987 - 89,083,217 (-) NCBI Rnor_5.0 1 90,230,830 - 90,240,520 (-) NCBI RGSC_v3.4 1 85,669,891 - 85,677,195 (-) RGD Celera 1 80,246,804 - 80,254,197 (-) RGD
Sequence:
CATCCAGGAGTCAGGATGGCCGAAGACATCAAGACTAAAATCAAGAACTACAAAACCGCCCCCTTTGACAGCCGCTTCCCAAACCAGAACCAGACTAAGAACTGCTGGCAGAACTACCTGGACTTCCA
hide sequence
RefSeq Acc Id:
XM_006228795 ⟹ XP_006228857
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 95,002,545 - 95,011,516 (-) NCBI mRatBN7.2 1 85,875,109 - 85,884,080 (-) NCBI Rnor_6.0 1 89,076,016 - 89,084,834 (-) NCBI Rnor_5.0 1 90,230,830 - 90,240,520 (-) NCBI
Sequence:
CAATTCGGCTTCTCCTCTTGCAGCTTCCGGCCAGTCGGAATTCCGCTTCCCGTCTGACATTGGC
hide sequence
RefSeq Acc Id:
XM_039091217 ⟹ XP_038947145
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 95,002,545 - 95,011,512 (-) NCBI mRatBN7.2 1 85,875,109 - 85,884,081 (-) NCBI
RefSeq Acc Id:
XM_063274412 ⟹ XP_063130482
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 95,002,545 - 95,011,428 (-) NCBI
RefSeq Acc Id:
XM_063274418 ⟹ XP_063130488
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 95,002,545 - 95,011,428 (-) NCBI
RefSeq Acc Id:
NP_001138745 ⟸ NM_001145273
- UniProtKB:
A0A8I6A8X0 (UniProtKB/TrEMBL), A6JA04 (UniProtKB/TrEMBL)
- Sequence:
MAEDIKTKIKNYKTAPFDSRFPNQNQTKNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPVSWVSAWDDRIAEGTFPGKI
hide sequence
RefSeq Acc Id:
XP_006228857 ⟸ XM_006228795
- Peptide Label:
isoform X1
- UniProtKB:
A0A8I6A8X0 (UniProtKB/TrEMBL), A6JA04 (UniProtKB/TrEMBL)
- Sequence:
MAEDIKTKIKNYKTAPFDSRFPNQNQTKNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPVSWVSAWDDRIAEGTFPGKI
hide sequence
Ensembl Acc Id:
ENSRNOP00000048723 ⟸ ENSRNOT00000045155
Ensembl Acc Id:
ENSRNOP00000030997 ⟸ ENSRNOT00000032026
RefSeq Acc Id:
XP_038947145 ⟸ XM_039091217
- Peptide Label:
isoform X2
- UniProtKB:
D3ZSB0 (UniProtKB/TrEMBL), A6JA04 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063130482 ⟸ XM_063274412
- Peptide Label:
isoform X1
- UniProtKB:
A6JA04 (UniProtKB/TrEMBL), A0A8I6A8X0 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063130488 ⟸ XM_063274418
- Peptide Label:
isoform X2
- UniProtKB:
A6JA04 (UniProtKB/TrEMBL), D3ZSB0 (UniProtKB/TrEMBL)
Additional Information
Nomenclature History
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-10-26
Cox6b1
cytochrome c oxidase subunit 6B1
Cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2009-02-17
Cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
LOC688869
similar to cytochrome c oxidase, subunit VIb polypeptide 1
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2006-11-19
LOC688869
similar to cytochrome c oxidase, subunit VIb polypeptide 1
Symbol and Name status set to provisional
70820 PROVISIONAL
