Rnf216 (ring finger protein 216) - Rat Genome Database

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Gene: Rnf216 (ring finger protein 216) Rattus norvegicus
Analyze
Symbol: Rnf216
Name: ring finger protein 216
RGD ID: 1565135
Description: Predicted to enable ubiquitin protein ligase activity. Involved in protein catabolic process, modulating synaptic transmission and regulation of postsynaptic neurotransmitter receptor internalization. Is active in several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic endocytic zone. Human ortholog(s) of this gene implicated in Gordon Holmes syndrome. Orthologous to human RNF216 (ring finger protein 216); INTERACTS WITH acrylamide; bisphenol A; cyclophosphamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase RNF216; LOC304294; RGD1565135; similar to E3 ubiquitin ligase TRIAD3B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,568,327 - 16,689,868 (+)NCBIGRCr8
mRatBN7.21211,454,752 - 11,576,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,454,797 - 11,576,304 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,263,009 - 12,386,275 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,886,286 - 13,009,554 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,912,387 - 12,035,725 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,508,429 - 13,631,689 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,508,429 - 13,632,304 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,547,724 - 15,668,304 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,850,549 - 11,968,127 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1213,249,412 - 13,370,214 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf216RatBaraitser-Winter syndrome 1  ISORNF216 (Homo sapiens)8554872ClinVar Annotator: match by term: Baraitser-Winter syndrome 1ClinVarPMID:27633570 more ...
Rnf216Ratgenetic disease  ISORNF216 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
Rnf216RatGordon Holmes syndrome  ISORNF216 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11932290 more ...
Rnf216Rathypogonadotropic hypogonadism 7 with or without anosmia  ISORNF216 (Homo sapiens)8554872ClinVar Annotator: match by term: Hypogonadotropic hypogonadism 7 with or without anosmiaClinVarPMID:25558065
Rnf216Ratrosette-forming glioneuronal tumor  ISORNF216 (Homo sapiens)8554872ClinVar Annotator: match by term: Rosette-forming glioneuronal tumorClinVarPMID:26822237 and PMID:27626068
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf216RatGordon Holmes syndrome  ISORNF216 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf216RatGordon Holmes syndrome  ISORNF216 (Homo sapiens)7240710 OMIM 

1 to 20 of 51 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf216Rat(-)-epigallocatechin 3-gallate multiple interactionsISORNF216 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RNF216 mRNACTDPMID:22079256
Rnf216Rat(1->4)-beta-D-glucan multiple interactionsISORnf216 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RNF216 mRNACTDPMID:36331819
Rnf216Rat1,2-dimethylhydrazine decreases expressionISORnf216 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of RNF216 mRNACTDPMID:22206623
Rnf216Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISORnf216 (Mus musculus)64804642 more ...CTDPMID:31388691
Rnf216Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORnf216 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of RNF216 mRNACTDPMID:19465110
Rnf216Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORnf216 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RNF216 mRNACTDPMID:21570461
Rnf216Rat4,4'-sulfonyldiphenol decreases expressionISORnf216 (Mus musculus)6480464bisphenol S results in decreased expression of RNF216 mRNACTDPMID:39298647
Rnf216Rat4,4'-sulfonyldiphenol multiple interactionsISORNF216 (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in decreased methylation of RNF216 geneCTDPMID:31601247
Rnf216Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of RNF216 mRNACTDPMID:28959563
Rnf216Ratarsane affects expressionISORNF216 (Homo sapiens)6480464Arsenic affects the expression of RNF216 mRNACTDPMID:18414638
Rnf216Ratarsane affects methylationISORNF216 (Homo sapiens)6480464Arsenic affects the methylation of RNF216 geneCTDPMID:25304211
Rnf216Ratarsenic atom affects expressionISORNF216 (Homo sapiens)6480464Arsenic affects the expression of RNF216 mRNACTDPMID:18414638
Rnf216Ratarsenic atom affects methylationISORNF216 (Homo sapiens)6480464Arsenic affects the methylation of RNF216 geneCTDPMID:25304211
Rnf216Ratatrazine decreases expressionISORNF216 (Homo sapiens)6480464Atrazine results in decreased expression of RNF216 mRNACTDPMID:22378314
Rnf216Ratbenzo[a]pyrene decreases expressionISORnf216 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of RNF216 mRNACTDPMID:22228805
Rnf216Ratbenzo[a]pyrene increases methylationISORNF216 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of RNF216 5' UTR and Benzo(a)pyrene results in increased methylation of RNF216 promoterCTDPMID:27901495
Rnf216Ratbenzo[a]pyrene multiple interactionsISORnf216 (Mus musculus)6480464AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RNF216 mRNA]CTDPMID:22228805
Rnf216Ratbis(2-ethylhexyl) phthalate decreases expressionISORnf216 (Mus musculus)6480464Diethylhexyl Phthalate results in decreased expression of RNF216 mRNACTDPMID:21318169
Rnf216Ratbisphenol A increases expressionISORnf216 (Mus musculus)6480464bisphenol A results in increased expression of RNF216 mRNACTDPMID:26063408
Rnf216Ratbisphenol A increases methylationISORnf216 (Mus musculus)6480464bisphenol A results in increased methylation of RNF216 promoterCTDPMID:27312807

1 to 20 of 51 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf216Ratcytosol located_inISORNF216 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rnf216Ratglutamatergic synapse is_active_inIMP 11553202PMID:24945773SynGO 
Rnf216Ratglutamatergic synapse is_active_inIDA 11553202PMID:24945773SynGO 
Rnf216Ratnucleoplasm located_inISORNF216 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rnf216Ratnucleus located_inISORNF216 (Homo sapiens)1624291 RGDGO_REF:0000054
Rnf216Ratpostsynaptic endocytic zone is_active_inIDA 11553202PMID:24945773SynGO 
Rnf216Ratpresynapse is_active_inIDA 11553202PMID:24945773SynGO 
Rnf216RatSchaffer collateral - CA1 synapse is_active_inIDA 11553202PMID:24945773SynGO 

Molecular Function

  


#
Reference Title
Reference Citation
1. Triad3A regulates synaptic strength by ubiquitination of Arc. Mabb AM, etal., Neuron. 2014 Jun 18;82(6):1299-316. doi: 10.1016/j.neuron.2014.05.016.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:19893624   PMID:32918771  



Rnf216
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,568,327 - 16,689,868 (+)NCBIGRCr8
mRatBN7.21211,454,752 - 11,576,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,454,797 - 11,576,304 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,263,009 - 12,386,275 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,886,286 - 13,009,554 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,912,387 - 12,035,725 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,508,429 - 13,631,689 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,508,429 - 13,632,304 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,547,724 - 15,668,304 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,850,549 - 11,968,127 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1213,249,412 - 13,370,214 (+)NCBICelera
Cytogenetic Map12p11NCBI
RNF216
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,620,047 - 5,781,663 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl75,620,047 - 5,781,696 (-)EnsemblGRCh38hg38GRCh38
GRCh3775,659,678 - 5,821,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,626,204 - 5,787,818 (-)NCBINCBI36Build 36hg18NCBI36
Celera75,619,295 - 5,780,893 (-)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef75,571,731 - 5,733,450 (-)NCBIHuRef
CHM1_175,659,283 - 5,820,961 (-)NCBICHM1_1
T2T-CHM13v2.075,737,579 - 5,899,098 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v275,706,017 - 5,867,706 (-)NCBI
Rnf216
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,976,648 - 143,098,793 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5142,976,648 - 143,098,749 (-)EnsemblGRCm39 Ensembl
GRCm385142,990,893 - 143,113,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,990,893 - 143,112,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv375143,752,572 - 143,874,673 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365143,256,033 - 143,378,134 (-)NCBIMGSCv36mm8
Celera5140,039,423 - 140,158,416 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.86NCBI
Rnf216
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,425,885 - 10,551,295 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546010,423,736 - 10,578,421 (-)NCBIChiLan1.0ChiLan1.0
RNF216
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,579,755 - 10,746,674 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1758,904,460 - 59,071,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v075,872,118 - 6,037,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.175,891,909 - 6,051,979 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl75,891,909 - 6,051,979 (-)Ensemblpanpan1.1panPan2
RNF216
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1612,185,870 - 12,347,461 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl612,185,846 - 12,361,869 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha613,690,975 - 13,819,412 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0612,279,451 - 12,440,387 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl612,279,466 - 12,483,247 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1612,133,461 - 12,294,697 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0612,067,337 - 12,228,144 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0612,343,974 - 12,505,522 (+)NCBIUU_Cfam_GSD_1.0
Rnf216
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344140,441,068 - 140,601,298 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936765473,025 - 589,681 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936765452,755 - 592,358 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF216
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,158,450 - 4,329,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,158,447 - 4,329,458 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,800,772 - 4,820,346 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF216
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12815,955,499 - 16,114,307 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2815,954,803 - 16,117,759 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660905,879,677 - 6,041,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf216
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474027,885,778 - 28,024,710 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474027,861,094 - 28,024,619 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Rnf216
633 total Variants

Predicted Target Of
Summary Value
Count of predictions:287
Count of miRNA genes:169
Interacting mature miRNAs:205
Transcripts:ENSRNOT00000001458
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat

1 to 10 of 38 rows
BE117877  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,504,190 - 11,504,383 (+)MAPPERmRatBN7.2
Rnor_6.01213,557,812 - 13,558,004NCBIRnor6.0
Rnor_5.01215,596,773 - 15,596,965UniSTSRnor5.0
RGSC_v3.41211,903,466 - 11,903,658UniSTSRGSC3.4
Celera1213,298,552 - 13,298,744UniSTS
RH 3.4 Map12154.3UniSTS
Cytogenetic Map12p11UniSTS
RH128286  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,575,887 - 11,576,068 (+)MAPPERmRatBN7.2
Rnor_6.01213,631,273 - 13,631,453NCBIRnor6.0
Rnor_5.01215,667,888 - 15,668,068UniSTSRnor5.0
Celera1213,369,798 - 13,369,978UniSTS
RH 3.4 Map12156.3UniSTS
Cytogenetic Map12p11UniSTS
RH137434  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,550,021 - 11,550,219 (+)MAPPERmRatBN7.2
Rnor_6.01213,605,249 - 13,605,446NCBIRnor6.0
Rnor_5.01215,641,864 - 15,642,061UniSTSRnor5.0
RGSC_v3.41211,949,352 - 11,949,549UniSTSRGSC3.4
Celera1213,343,917 - 13,344,114UniSTS
Cytogenetic Map12p11UniSTS
RH137509  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,470,103 - 11,470,644 (+)MAPPERmRatBN7.2
mRatBN7.21234,761,961 - 34,762,178 (+)MAPPERmRatBN7.2
Rnor_6.01240,274,101 - 40,274,317NCBIRnor6.0
Rnor_6.01213,523,743 - 13,524,283NCBIRnor6.0
Rnor_5.01242,145,058 - 42,145,274UniSTSRnor5.0
Rnor_5.01215,562,742 - 15,563,282UniSTSRnor5.0
RGSC_v3.41235,966,790 - 35,967,006UniSTSRGSC3.4
RGSC_v3.41211,865,825 - 11,866,365UniSTSRGSC3.4
Celera1213,264,657 - 13,265,197UniSTS
Celera1236,426,782 - 36,426,998UniSTS
RH 3.4 Map12616.2UniSTS
Cytogenetic Map12q16UniSTS
Cytogenetic Map12p11UniSTS
RH140401  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,459,101 - 11,459,318 (+)MAPPERmRatBN7.2
Rnor_6.01213,512,742 - 13,512,958NCBIRnor6.0
Rnor_5.01215,551,741 - 15,551,957UniSTSRnor5.0
RGSC_v3.41211,854,823 - 11,855,039UniSTSRGSC3.4
Celera1213,253,666 - 13,253,882UniSTS
RH 3.4 Map12154.5UniSTS
Cytogenetic Map12p11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000001458   ⟹   ENSRNOP00000001458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1211,454,797 - 11,576,304 (+)Ensembl
Rnor_6.0 Ensembl1213,508,429 - 13,631,689 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083976   ⟹   ENSRNOP00000074315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1213,508,933 - 13,632,304 (+)Ensembl
RefSeq Acc Id: NM_001107122   ⟹   NP_001100592
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,373 - 16,689,867 (+)NCBI
mRatBN7.21211,454,797 - 11,576,304 (+)NCBI
Rnor_6.01213,508,429 - 13,631,689 (+)NCBI
Rnor_5.01215,547,724 - 15,668,304 (+)NCBI
RGSC_v3.41211,850,549 - 11,968,127 (+)RGD
Celera1213,249,412 - 13,370,214 (+)RGD
Sequence:
RefSeq Acc Id: XM_039089363   ⟹   XP_038945291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,391 - 16,689,868 (+)NCBI
mRatBN7.21211,454,816 - 11,576,305 (+)NCBI
RefSeq Acc Id: XM_039089364   ⟹   XP_038945292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,327 - 16,689,868 (+)NCBI
mRatBN7.21211,454,752 - 11,576,305 (+)NCBI
RefSeq Acc Id: XM_039089366   ⟹   XP_038945294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,887 - 16,689,868 (+)NCBI
mRatBN7.21211,455,312 - 11,576,305 (+)NCBI
RefSeq Acc Id: XM_039089367   ⟹   XP_038945295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,391 - 16,689,868 (+)NCBI
mRatBN7.21211,454,816 - 11,576,305 (+)NCBI
RefSeq Acc Id: XM_063271261   ⟹   XP_063127331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,327 - 16,689,868 (+)NCBI
RefSeq Acc Id: XM_063271262   ⟹   XP_063127332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,568,887 - 16,689,868 (+)NCBI
RefSeq Acc Id: NP_001100592   ⟸   NM_001107122
- UniProtKB: D3ZU60 (UniProtKB/TrEMBL),   A6K1N1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074315   ⟸   ENSRNOT00000083976
Ensembl Acc Id: ENSRNOP00000001458   ⟸   ENSRNOT00000001458
RefSeq Acc Id: XP_038945292   ⟸   XM_039089364
- Peptide Label: isoform X1
- UniProtKB: D3ZU60 (UniProtKB/TrEMBL),   A6K1N1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945291   ⟸   XM_039089363
- Peptide Label: isoform X1
- UniProtKB: D3ZU60 (UniProtKB/TrEMBL),   A6K1N1 (UniProtKB/TrEMBL)
RING-type

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZU60-F1-model_v2 AlphaFold D3ZU60 1-910 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698444
Promoter ID:EPDNEW_R8969
Type:initiation region
Name:Rnf216_1
Description:ring finger protein 216
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01213,508,432 - 13,508,492EPDNEW


1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19988 BioCyc
Ensembl Genes ENSRNOG00000001101 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001458 ENTREZGENE
  ENSRNOT00000001458.8 UniProtKB/TrEMBL
  ENSRNOT00000157770 ENTREZGENE
Gene3D-CATH 1.20.120.1750 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro BRcat_RBR_RNF216 UniProtKB/TrEMBL
  LUBAC_E3_Ligases UniProtKB/TrEMBL
  Rcat_RBR_RNF216 UniProtKB/TrEMBL
  RING-HC_RBR_RNF216 UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/TrEMBL
  Znf_C6HC UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:304294 UniProtKB/TrEMBL
NCBI Gene 304294 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF216 UniProtKB/TrEMBL
  UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED UniProtKB/TrEMBL
Pfam IBR_1 UniProtKB/TrEMBL
PhenoGen Rnf216 PhenoGen
PROSITE TRIAD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001101 RatGTEx
SMART IBR UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A6K1N1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZU60 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Rnf216  ring finger protein 216  RGD1565135_predicted  similar to E3 ubiquitin ligase TRIAD3B (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565135_predicted  similar to E3 ubiquitin ligase TRIAD3B (predicted)  LOC304294  similar to E3 ubiquitin ligase TRIAD3B  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC304294  similar to E3 ubiquitin ligase TRIAD3B      Symbol and Name status set to provisional 70820 PROVISIONAL