Bach2 (BTB domain and CNC homolog 2) - Rat Genome Database

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Gene: Bach2 (BTB domain and CNC homolog 2) Rattus norvegicus
Analyze
Symbol: Bach2
Name: BTB domain and CNC homolog 2
RGD ID: 1562865
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in import into nucleus; negative regulation of transcription by RNA polymerase II; and primary adaptive immune response involving T cells and B cells. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BTB and CNC homology 1, basic leucine zipper transcription factor 2; BTB and CNC homology 2; LOC313125; RGD1562865; similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2; transcription regulator protein BACH2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,428,802 - 51,779,030 (+)NCBIGRCr8
mRatBN7.2546,632,338 - 46,982,676 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl546,638,317 - 46,977,877 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx548,859,726 - 49,119,822 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,458,890 - 50,718,988 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,402,412 - 50,664,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,458,891 - 47,807,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,546,014 - 47,807,166 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,073,295 - 52,410,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,611,805 - 48,881,943 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera545,479,904 - 45,738,863 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2Ratimmunodeficiency 60  ISOBACH2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Bach2Ratprimary ciliary dyskinesia 3  ISOBACH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary ciliary dyskinesia 3ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2Ratacute myeloid leukemia  ISOBACH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21441929
Bach2Ratceliac disease  ISOBACH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20190752
Bach2RatCrohn's disease  ISOBACH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21102463
Bach2Rattype 1 diabetes mellitus  ISOBACH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18978792
Bach2Ratvitiligo  ISOBACH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22561518
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2Ratimmunodeficiency 60  ISOBACH2 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2Rat(-)-anisomycin increases expressionISOBACH2 (Homo sapiens)6480464Anisomycin results in increased expression of BACH2 mRNACTDPMID:24247028
Bach2Rat1,1-dichloroethene decreases expressionISOBach2 (Mus musculus)6480464vinylidene chloride results in decreased expression of BACH2 mRNACTDPMID:26682919
Bach2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of BACH2 mRNACTDPMID:29097150
Bach2Rat17beta-estradiol multiple interactionsISOBACH2 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of BACH2 mRNACTDPMID:30165855
Bach2Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of BACH2 mRNACTDPMID:32145629
Bach2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOBach2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] promotes the reaction [BACH2 protein binds to PRDM1 intron] more ...CTDPMID:19654925 more ...
Bach2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of BACH2 mRNACTDPMID:33387578
Bach2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of BACH2 mRNACTDPMID:32109520
Bach2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOBach2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of BACH2 mRNACTDPMID:21570461
Bach2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOBach2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of BACH2 mRNACTDPMID:20819909 more ...
Bach2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOBach2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of BACH2 mRNACTDPMID:19770486
Bach2Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Bach2Rat2-butoxyethanol decreases expressionISOBach2 (Mus musculus)6480464n-butoxyethanol results in decreased expression of BACH2 mRNACTDPMID:19812364
Bach2Rat3,3',4,4',5-pentachlorobiphenyl decreases expressionEXP 64804643 more ...CTDPMID:32119087
Bach2Rat3,4-methylenedioxymethamphetamine decreases expressionISOBach2 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of BACH2 mRNACTDPMID:20188158
Bach2Rat4,4'-sulfonyldiphenol decreases expressionISOBACH2 (Homo sapiens)6480464bisphenol S results in decreased expression of BACH2 mRNACTDPMID:30616060
Bach2Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of BACH2 mRNACTDPMID:24780913 and PMID:25825206
Bach2Rataflatoxin B1 decreases expressionISOBach2 (Mus musculus)6480464Aflatoxin B1 results in decreased expression of BACH2 mRNACTDPMID:19770486
Bach2Rataflatoxin B1 increases methylationISOBACH2 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of BACH2 geneCTDPMID:27153756
Bach2Ratalpha-Zearalanol increases expressionEXP 6480464Zeranol results in increased expression of BACH2 mRNACTDPMID:35163327

1 to 20 of 94 rows

Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2Ratimport into nucleus involved_inISOBach2 (Mus musculus)1624291 PMID:26021350RGDPMID:26021350
Bach2Ratimport into nucleus involved_inIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratnegative regulation of transcription by RNA polymerase II involved_inISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2Ratnegative regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratprimary adaptive immune response involving T cells and B cells involved_inISOBACH2 (Homo sapiens)1624291 PMID:28530713RGDPMID:28530713
Bach2Ratprimary adaptive immune response involving T cells and B cells involved_inIEAUniProtKB:Q9BYV9 and ensembl:ENSP000002577491600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratregulation of DNA-templated transcription acts_upstream_of_or_withinIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratregulation of DNA-templated transcription acts_upstream_of_or_withinISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2Ratregulation of DNA-templated transcription involved_inIEAInterPro:IPR004826 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Bach2Ratregulation of transcription by RNA polymerase II involved_inIBAMGI:102755 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 10 of 10 rows

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2Ratcytosol located_inISOBACH2 (Homo sapiens)1624291 RGDGO_REF:0000052
Bach2Ratcytosol located_inIEAUniProtKB:Q9BYV9 and ensembl:ENSP000002577491600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratnucleoplasm located_inISOBACH2 (Homo sapiens)1624291 RGDGO_REF:0000052
Bach2Ratnucleoplasm located_inIEAUniProtKB:Q9BYV9 and ensembl:ENSP000002577491600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Bach2Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Bach2Ratnucleus located_inIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratnucleus located_inISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2RatRNA polymerase II transcription regulator complex part_ofISOBACH2 (Homo sapiens)1624291 PMID:22194330 and PMID:23661758RGDPMID:22194330 and PMID:23661758
Bach2RatRNA polymerase II transcription regulator complex part_ofIEAUniProtKB:Q9BYV9 and ensembl:ENSP000002577491600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 10 of 10 rows

Molecular Function
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bach2RatDNA binding enablesIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2RatDNA binding enablesIEAInterPro:IPR004826 and InterPro:IPR0089171600115GO_REF:0000002InterProGO_REF:0000002
Bach2RatDNA binding enablesISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Bach2RatDNA-binding transcription factor activity enablesIEAInterPro:IPR004827 and InterPro:IPR0463471600115GO_REF:0000002InterProGO_REF:0000002
Bach2RatDNA-binding transcription factor activity enablesIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2RatDNA-binding transcription factor activity enablesISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAMGI:102755 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Bach2RatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2RatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2Ratprotein binding enablesISOBACH2 (Homo sapiens)1624291UniProtKB:O15525 more ...RGDPMID:23661758 more ...
Bach2Ratprotein binding enablesISOBach2 (Mus musculus)1624291PR:Q61827 PMID:8887638RGDPMID:8887638
Bach2RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOBach2 (Mus musculus)1624291 PMID:8887638RGDPMID:8887638
Bach2RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAUniProtKB:P97303 and ensembl:ENSMUSP000001038151600115GO_REF:0000107EnsemblGO_REF:0000107
Bach2RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIBAMGI:102755 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Bach2Ratsequence-specific double-stranded DNA binding enablesISOBACH2 (Homo sapiens)1624291 PMID:28473536RGDPMID:28473536
Bach2Ratsequence-specific double-stranded DNA binding enablesIEAUniProtKB:Q9BYV9 and ensembl:ENSP000002577491600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 17 of 17 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8887638   PMID:26021350   PMID:28530713  



Bach2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,428,802 - 51,779,030 (+)NCBIGRCr8
mRatBN7.2546,632,338 - 46,982,676 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl546,638,317 - 46,977,877 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx548,859,726 - 49,119,822 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,458,890 - 50,718,988 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,402,412 - 50,664,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,458,891 - 47,807,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,546,014 - 47,807,166 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,073,295 - 52,410,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,611,805 - 48,881,943 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera545,479,904 - 45,738,863 (+)NCBICelera
Cytogenetic Map5q21NCBI
BACH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,926,528 - 90,296,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,926,528 - 90,296,843 (-)EnsemblGRCh38hg38GRCh38
GRCh37690,636,247 - 91,006,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,692,969 - 91,063,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 34690,692,968 - 91,063,182NCBI
Celera691,056,791 - 91,427,144 (-)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,855,580 - 88,225,476 (-)NCBIHuRef
CHM1_1690,733,911 - 91,104,124 (-)NCBICHM1_1
T2T-CHM13v2.0691,138,217 - 91,508,429 (-)NCBIT2T-CHM13v2.0
Bach2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,238,413 - 32,586,109 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,238,804 - 32,586,108 (+)EnsemblGRCm39 Ensembl
GRCm38432,238,413 - 32,586,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,238,804 - 32,586,108 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,504,410 - 32,673,083 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,567,563 - 32,909,812 (+)NCBIMGSCv36mm8
Celera432,164,289 - 32,333,354 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.02NCBI
Bach2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541116,613,397 - 16,877,834 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541116,607,546 - 16,947,359 (-)NCBIChiLan1.0ChiLan1.0
BACH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25110,011,721 - 110,381,491 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,912,858 - 108,282,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,806,188 - 88,175,840 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1691,081,381 - 91,212,497 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl691,083,533 - 91,160,552 (-)Ensemblpanpan1.1panPan2
BACH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11249,101,621 - 49,375,415 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1249,106,523 - 49,460,286 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,908,403 - 49,267,597 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,910,921 - 50,270,587 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,916,822 - 50,270,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11249,225,818 - 49,503,613 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01249,126,581 - 49,485,448 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01249,318,946 - 49,677,611 (-)NCBIUU_Cfam_GSD_1.0
Bach2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494684,094,552 - 84,429,900 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,299,831 - 2,371,544 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,041,004 - 2,375,215 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BACH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,899,808 - 58,281,430 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,881,203 - 58,281,740 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,904,041 - 65,200,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BACH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,681,323 - 15,049,690 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,687,188 - 14,763,706 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040191,077,385 - 191,445,395 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bach2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247993,984,546 - 4,256,898 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247993,893,548 - 4,262,344 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Bach2
2874 total Variants

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:121
Interacting mature miRNAs:156
Transcripts:ENSRNOT00000065882
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat

1 to 10 of 30 rows
RH133931  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,758,809 - 46,759,116 (+)MAPPERmRatBN7.2
mRatBN7.2546,758,905 - 46,759,116 (+)MAPPERmRatBN7.2
Rnor_6.0547,588,111 - 47,588,321NCBIRnor6.0
Rnor_6.0547,587,893 - 47,588,321NCBIRnor6.0
Rnor_5.0552,193,349 - 52,193,777UniSTSRnor5.0
Rnor_5.0552,193,567 - 52,193,777UniSTSRnor5.0
RGSC_v3.4548,653,687 - 48,653,897UniSTSRGSC3.4
Celera545,521,752 - 45,521,962UniSTS
RH 3.4 Map5258.8UniSTS
Cytogenetic Map5q21UniSTS
BE107542  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,860,201 - 46,860,366 (+)MAPPERmRatBN7.2
Rnor_6.0547,689,834 - 47,689,998NCBIRnor6.0
Rnor_5.0552,294,106 - 52,294,270UniSTSRnor5.0
RGSC_v3.4548,754,752 - 48,754,916UniSTSRGSC3.4
Celera545,622,919 - 45,623,083UniSTS
RH 3.4 Map5263.6UniSTS
Cytogenetic Map5q21UniSTS
BF403939  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,721,893 - 46,722,074 (+)MAPPERmRatBN7.2
Rnor_6.0547,550,887 - 47,551,067NCBIRnor6.0
Rnor_5.0552,156,343 - 52,156,523UniSTSRnor5.0
RGSC_v3.4548,616,678 - 48,616,858UniSTSRGSC3.4
Celera545,484,777 - 45,484,957UniSTS
RH 3.4 Map5247.6UniSTS
Cytogenetic Map5q21UniSTS
BI301153  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,976,986 - 46,977,146 (+)MAPPERmRatBN7.2
Rnor_6.0547,806,276 - 47,806,435NCBIRnor6.0
Rnor_5.0552,410,010 - 52,410,169UniSTSRnor5.0
RGSC_v3.4548,881,043 - 48,881,202UniSTSRGSC3.4
Celera545,737,963 - 45,738,122UniSTS
RH 3.4 Map5246.7UniSTS
Cytogenetic Map5q21UniSTS
BE120871  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,836,451 - 46,836,636 (+)MAPPERmRatBN7.2
Rnor_6.0547,665,397 - 47,665,581NCBIRnor6.0
Rnor_5.0552,270,853 - 52,271,037UniSTSRnor5.0
RGSC_v3.4548,731,454 - 48,731,638UniSTSRGSC3.4
Celera545,599,222 - 45,599,406UniSTS
RH 3.4 Map5247.2UniSTS
Cytogenetic Map5q21UniSTS
BF406327  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,806,365 - 46,806,576 (+)MAPPERmRatBN7.2
Rnor_6.0547,635,312 - 47,635,522NCBIRnor6.0
Rnor_5.0552,240,768 - 52,240,978UniSTSRnor5.0
RGSC_v3.4548,701,370 - 48,701,580UniSTSRGSC3.4
Celera545,569,145 - 45,569,355UniSTS
RH 3.4 Map5247.6UniSTS
Cytogenetic Map5q21UniSTS
AU047697  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,744,932 - 46,745,077 (+)MAPPERmRatBN7.2
Rnor_6.0547,573,923 - 47,574,067NCBIRnor6.0
Rnor_5.0552,179,379 - 52,179,523UniSTSRnor5.0
RGSC_v3.4548,639,715 - 48,639,859UniSTSRGSC3.4
Celera545,507,792 - 45,507,923UniSTS
Cytogenetic Map5q21UniSTS
AU048907  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8551,531,956 - 51,532,221 (+)Marker Load Pipeline
mRatBN7.2546,735,574 - 46,735,839 (+)MAPPERmRatBN7.2
Rnor_6.0547,564,566 - 47,564,830NCBIRnor6.0
Rnor_5.0552,170,022 - 52,170,286UniSTSRnor5.0
RGSC_v3.4548,630,357 - 48,630,621UniSTSRGSC3.4
Celera545,498,435 - 45,498,699UniSTS
Cytogenetic Map5q21UniSTS
AU049667  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2546,949,542 - 46,949,794 (+)MAPPERmRatBN7.2
Rnor_6.0547,778,836 - 47,779,087NCBIRnor6.0
Rnor_5.0552,382,570 - 52,382,821UniSTSRnor5.0
RGSC_v3.4548,853,602 - 48,853,853UniSTSRGSC3.4
Celera545,710,547 - 45,710,798UniSTS
Cytogenetic Map5q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000065882   ⟹   ENSRNOP00000063410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl546,717,021 - 46,977,877 (+)Ensembl
Rnor_6.0 Ensembl547,546,014 - 47,807,166 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098834   ⟹   ENSRNOP00000076760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl546,713,203 - 46,896,202 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113651   ⟹   ENSRNOP00000090267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl546,638,317 - 46,939,764 (+)Ensembl
RefSeq Acc Id: NM_001135754   ⟹   NP_001129226
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,513,405 - 51,774,244 (+)NCBI
mRatBN7.2546,717,021 - 46,977,887 (+)NCBI
Rnor_6.0547,546,014 - 47,807,176 (+)NCBI
Rnor_5.0552,073,295 - 52,410,910 (+)NCBI
RGSC_v3.4548,611,805 - 48,881,943 (+)RGD
Celera545,479,904 - 45,738,863 (+)RGD
Sequence:
RefSeq Acc Id: XM_017593345   ⟹   XP_017448834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,435,017 - 51,779,030 (+)NCBI
mRatBN7.2546,637,970 - 46,982,676 (+)NCBI
Rnor_6.0547,466,611 - 47,807,123 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593347   ⟹   XP_017448836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,435,176 - 51,779,030 (+)NCBI
mRatBN7.2546,638,790 - 46,982,676 (+)NCBI
Rnor_6.0547,467,026 - 47,807,123 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593349   ⟹   XP_017448838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,428,802 - 51,779,030 (+)NCBI
mRatBN7.2546,632,338 - 46,982,676 (+)NCBI
Rnor_6.0547,458,891 - 47,807,123 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109820   ⟹   XP_038965748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,497,518 - 51,779,030 (+)NCBI
mRatBN7.2546,701,131 - 46,982,676 (+)NCBI
RefSeq Acc Id: XM_039109821   ⟹   XP_038965749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,436,825 - 51,779,030 (+)NCBI
mRatBN7.2546,640,437 - 46,982,676 (+)NCBI
RefSeq Acc Id: XR_005504432
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,435,017 - 51,779,030 (+)NCBI
mRatBN7.2546,637,970 - 46,982,676 (+)NCBI
RefSeq Acc Id: XR_010066378
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,435,017 - 51,779,030 (+)NCBI
RefSeq Acc Id: XR_010066379
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,435,017 - 51,779,030 (+)NCBI
RefSeq Acc Id: NP_001129226   ⟸   NM_001135754
- UniProtKB: D3ZW33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448838   ⟸   XM_017593349
- Peptide Label: isoform X1
- UniProtKB: D3ZW33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448834   ⟸   XM_017593345
- Peptide Label: isoform X1
- UniProtKB: D3ZW33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448836   ⟸   XM_017593347
- Peptide Label: isoform X1
- UniProtKB: D3ZW33 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063410   ⟸   ENSRNOT00000065882
BTB   bZIP

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZW33-F1-model_v2 AlphaFold D3ZW33 1-839 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 36 of 36 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-41727 BioCyc
Ensembl Genes ENSRNOG00000006170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065882 ENTREZGENE
  ENSRNOT00000065882.2 UniProtKB/TrEMBL
  ENSRNOT00000098834.1 UniProtKB/TrEMBL
  ENSRNOT00000113651 ENTREZGENE
  ENSRNOT00000113651.1 UniProtKB/TrEMBL
Gene3D-CATH Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
  Transcription factor, Skn-1-like, DNA-binding domain UniProtKB/TrEMBL
InterPro BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  bZIP UniProtKB/TrEMBL
  bZIP_BACH UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
  Euk_TF_DNA-bd UniProtKB/TrEMBL
  ZnFinger_BTB_dom_contain UniProtKB/TrEMBL
KEGG Report rno:313125 UniProtKB/TrEMBL
NCBI Gene 313125 ENTREZGENE
PANTHER AGAP004733-PA UniProtKB/TrEMBL
  TRANSCRIPTION REGULATOR PROTEIN BACH2 UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
PhenoGen Bach2 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
  BZIP UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006170 RatGTEx
SMART BRLZ UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  Euk_transcr_DNA UniProtKB/TrEMBL
  SSF57959 UniProtKB/TrEMBL
UniProt A0A8I5Y0R0_RAT UniProtKB/TrEMBL
  A0A8I6AMQ4_RAT UniProtKB/TrEMBL
  D3ZW33 ENTREZGENE, UniProtKB/TrEMBL
1 to 36 of 36 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Bach2  BTB domain and CNC homolog 2  Bach2  BTB and CNC homology 1, basic leucine zipper transcription factor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-01 Bach2  BTB and CNC homology 1, basic leucine zipper transcription factor 2  RGD1562865  similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562865  similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2   RGD1562865_predicted  similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562865_predicted  similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2 (predicted)  LOC313125  similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC313125  similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2      Symbol and Name status set to provisional 70820 PROVISIONAL