Rad51b (RAD51 paralog B) - Rat Genome Database

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Gene: Rad51b (RAD51 paralog B) Rattus norvegicus
Analyze
Symbol: Rad51b
Name: RAD51 paralog B
RGD ID: 1560681
Description: Predicted to enable ATP-dependent activity, acting on DNA; double-stranded DNA binding activity; and single-stranded DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination and positive regulation of G2/M transition of mitotic cell cycle. Predicted to act upstream of or within blastocyst growth; positive regulation of cell population proliferation; and somite development. Predicted to be located in replication fork. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Orthologous to human RAD51B (RAD51 paralog B); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 1-naphthyl isothiocyanate; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA repair protein RAD51 homolog 2; LOC500679; RAD51 homolog B; RAD51 homolog B (S. cerevisiae); RAD51-like 1; RAD51-like 1 (S. cerevisiae); Rad51l1; RGD1560681; similar to RAD51-like 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,829,390 - 104,373,923 (+)NCBIGRCr8
mRatBN7.2698,096,525 - 98,640,988 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,525,988 - 99,062,959 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,825,134 - 99,362,047 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,211,622 - 98,750,469 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,473,978 - 103,018,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,160,014 - 115,699,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46102,069,799 - 102,134,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera696,481,576 - 97,009,269 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-palmitoylglycerol  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
fenofibrate  (ISO)
formaldehyde  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
glucose  (ISO)
glycidol  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
myristicin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
Ptaquiloside  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of homologous recombination in eukaryotes. Heyer WD, etal., Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10567591   PMID:11751635   PMID:12441335   PMID:20207730   PMID:23108668   PMID:23149936  


Genomics

Comparative Map Data
Rad51b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,829,390 - 104,373,923 (+)NCBIGRCr8
mRatBN7.2698,096,525 - 98,640,988 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,525,988 - 99,062,959 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,825,134 - 99,362,047 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,211,622 - 98,750,469 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,473,978 - 103,018,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,160,014 - 115,699,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46102,069,799 - 102,134,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera696,481,576 - 97,009,269 (+)NCBICelera
Cytogenetic Map6q24NCBI
RAD51B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,819,779 - 68,683,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,819,779 - 68,730,218 (+)EnsemblGRCh38hg38GRCh38
GRCh371468,286,496 - 69,149,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,356,262 - 68,132,367 (+)NCBINCBI36Build 36hg18NCBI36
Build 341467,356,261 - 68,014,562NCBI
Celera1448,345,516 - 49,121,494 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1448,455,813 - 49,231,230 (+)NCBIHuRef
CHM1_11468,225,211 - 69,001,135 (+)NCBICHM1_1
T2T-CHM13v2.01462,026,883 - 62,889,971 (+)NCBIT2T-CHM13v2.0
Rad51b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391279,344,032 - 79,895,034 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1279,344,056 - 79,861,464 (+)EnsemblGRCm39 Ensembl
GRCm381279,297,282 - 79,848,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1279,297,282 - 79,814,690 (+)EnsemblGRCm38mm10GRCm38
MGSCv371280,398,269 - 80,915,677 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361280,216,122 - 80,733,530 (+)NCBIMGSCv36mm8
Celera1280,761,261 - 81,278,996 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Rad51b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,137,192 - 2,381,450 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554661,686,472 - 2,388,146 (-)NCBIChiLan1.0ChiLan1.0
RAD51B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,926,972 - 69,844,939 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11468,145,747 - 69,061,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01448,399,345 - 49,314,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11467,277,400 - 68,189,780 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1467,281,148 - 68,110,693 (+)Ensemblpanpan1.1panPan2
RAD51B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,779,435 - 42,357,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,778,714 - 42,357,298 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha841,469,217 - 42,151,951 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0842,009,371 - 42,691,934 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl842,009,155 - 42,586,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,624,025 - 42,306,963 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,699,024 - 42,381,539 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0842,056,861 - 42,740,806 (+)NCBIUU_Cfam_GSD_1.0
Rad51b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864062,431,048 - 62,999,072 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649511,195,767 - 11,467,458 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649511,185,560 - 11,762,254 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD51B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl791,592,424 - 92,345,294 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1791,592,413 - 92,301,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2797,899,832 - 98,613,557 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAD51B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12445,056,485 - 45,704,394 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605333,285,609 - 34,057,636 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad51b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473432,560,579 - 33,173,357 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rad51b
3265 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat

Markers in Region
D6Wox4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,333,755 - 98,333,915 (+)MAPPERmRatBN7.2
Rnor_6.06102,717,943 - 102,718,100NCBIRnor6.0
Rnor_5.06115,398,337 - 115,398,494UniSTSRnor5.0
RGSC_v3.46102,452,430 - 102,452,587UniSTSRGSC3.4
RGSC_v3.46102,452,429 - 102,452,587RGDRGSC3.4
RGSC_v3.16102,455,886 - 102,456,043RGD
Celera696,711,893 - 96,712,050UniSTS
RH 3.4 Map6692.5UniSTS
RH 3.4 Map6692.5RGD
RH 2.0 Map6901.7RGD
Cytogenetic Map6q24UniSTS
D6Got121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,551,637 - 98,551,864 (+)MAPPERmRatBN7.2
Rnor_6.06102,931,707 - 102,931,933NCBIRnor6.0
Rnor_5.06115,611,771 - 115,611,997UniSTSRnor5.0
RGSC_v3.46102,675,640 - 102,675,867RGDRGSC3.4
RGSC_v3.46102,675,641 - 102,675,867UniSTSRGSC3.4
RGSC_v3.16102,679,097 - 102,679,323RGD
Celera696,920,677 - 96,920,903UniSTS
RH 3.4 Map6697.2UniSTS
RH 3.4 Map6697.2RGD
Cytogenetic Map6q24UniSTS
AI553500  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,640,695 - 98,640,830 (+)MAPPERmRatBN7.2
Rnor_6.06103,017,893 - 103,018,027NCBIRnor6.0
Rnor_5.06115,698,820 - 115,698,954UniSTSRnor5.0
Celera697,008,977 - 97,009,111UniSTS
Cytogenetic Map6q24UniSTS
AI326150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,280,851 - 98,280,977 (+)MAPPERmRatBN7.2
Rnor_6.06102,664,014 - 102,664,139NCBIRnor6.0
Rnor_5.06115,345,540 - 115,345,665UniSTSRnor5.0
RGSC_v3.46102,399,647 - 102,399,772UniSTSRGSC3.4
Celera696,659,301 - 96,659,426UniSTS
Cytogenetic Map6q24UniSTS
RH139568  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,640,666 - 98,640,846 (+)MAPPERmRatBN7.2
Rnor_6.06103,017,864 - 103,018,043NCBIRnor6.0
Rnor_5.06115,698,791 - 115,698,970UniSTSRnor5.0
Celera697,008,948 - 97,009,127UniSTS
Cytogenetic Map6q24UniSTS
AW532941  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,166,307 - 98,166,491 (+)MAPPERmRatBN7.2
Rnor_6.06102,547,417 - 102,547,600NCBIRnor6.0
Rnor_5.06115,228,274 - 115,228,457UniSTSRnor5.0
RGSC_v3.46102,139,254 - 102,139,437UniSTSRGSC3.4
Celera696,549,894 - 96,550,077UniSTS
RH 3.4 Map6691.7UniSTS
Cytogenetic Map6q24UniSTS
RH139454  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,640,635 - 98,640,755 (+)MAPPERmRatBN7.2
Rnor_6.06103,017,833 - 103,017,952NCBIRnor6.0
Rnor_5.06115,698,760 - 115,698,879UniSTSRnor5.0
Celera697,008,917 - 97,009,036UniSTS
RH 3.4 Map6692.0UniSTS
Cytogenetic Map6q24UniSTS
AU049680  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,522,003 - 98,522,231 (+)MAPPERmRatBN7.2
Rnor_6.06102,903,893 - 102,904,118NCBIRnor6.0
Rnor_5.06115,583,963 - 115,584,188UniSTSRnor5.0
RGSC_v3.46102,643,644 - 102,643,869UniSTSRGSC3.4
Celera696,893,688 - 96,893,913UniSTS
Cytogenetic Map6q24UniSTS
Fzd6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,100,874 - 98,100,975 (+)MAPPERmRatBN7.2
Rnor_6.06102,478,321 - 102,478,421NCBIRnor6.0
Rnor_5.06115,164,269 - 115,164,369UniSTSRnor5.0
RGSC_v3.46102,071,084 - 102,071,184UniSTSRGSC3.4
Celera696,485,919 - 96,486,019UniSTS
Cytogenetic Map6q24UniSTS
Cytogenetic Map7q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5 5 1
Low 3 43 47 36 14 36 8 8 70 35 40 11 8
Below cutoff 4 4 4 2 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000087132   ⟹   ENSRNOP00000068685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl698,099,575 - 98,323,866 (+)Ensembl
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105193   ⟹   ENSRNOP00000084086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl698,099,575 - 98,640,979 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116880   ⟹   ENSRNOP00000091401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)Ensembl
RefSeq Acc Id: NM_001399175   ⟹   NP_001386104
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,554 - 104,373,923 (+)NCBI
mRatBN7.2698,096,571 - 98,640,988 (+)NCBI
RefSeq Acc Id: XM_017594475   ⟹   XP_017449964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,493 - 104,373,905 (+)NCBI
mRatBN7.2698,096,525 - 98,640,988 (+)NCBI
Rnor_6.06102,473,993 - 103,018,185 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594476   ⟹   XP_017449965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,391 - 104,369,164 (+)NCBI
mRatBN7.2698,096,525 - 98,637,105 (+)NCBI
Rnor_6.06102,473,993 - 103,014,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039113277   ⟹   XP_038969205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,495 - 104,369,164 (+)NCBI
mRatBN7.2698,096,525 - 98,637,105 (+)NCBI
RefSeq Acc Id: XM_039113278   ⟹   XP_038969206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,536 - 104,369,164 (+)NCBI
mRatBN7.2698,096,535 - 98,637,105 (+)NCBI
RefSeq Acc Id: XM_039113279   ⟹   XP_038969207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,497 - 104,373,905 (+)NCBI
mRatBN7.2698,096,526 - 98,640,988 (+)NCBI
RefSeq Acc Id: XM_039113281   ⟹   XP_038969209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,494 - 104,369,164 (+)NCBI
mRatBN7.2698,096,525 - 98,637,105 (+)NCBI
RefSeq Acc Id: XM_039113282   ⟹   XP_038969210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,492 - 104,297,936 (+)NCBI
mRatBN7.2698,096,525 - 98,564,940 (+)NCBI
RefSeq Acc Id: XM_039113283   ⟹   XP_038969211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,492 - 103,906,996 (+)NCBI
mRatBN7.2698,096,525 - 98,167,202 (+)NCBI
RefSeq Acc Id: XM_063262317   ⟹   XP_063118387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,530 - 103,906,996 (+)NCBI
RefSeq Acc Id: XR_005506073
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,495 - 104,373,905 (+)NCBI
mRatBN7.2698,096,525 - 98,640,988 (+)NCBI
RefSeq Acc Id: XR_010052147
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,390 - 104,373,905 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_017449964   ⟸   XM_017594475
- Peptide Label: isoform X4
- UniProtKB: A6HCH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449965   ⟸   XM_017594476
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068685   ⟸   ENSRNOT00000087132
RefSeq Acc Id: XP_038969205   ⟸   XM_039113277
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038969209   ⟸   XM_039113281
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AFI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969210   ⟸   XM_039113282
- Peptide Label: isoform X6
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969211   ⟸   XM_039113283
- Peptide Label: isoform X7
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969207   ⟸   XM_039113279
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZYE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969206   ⟸   XM_039113278
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000084086   ⟸   ENSRNOT00000105193
RefSeq Acc Id: ENSRNOP00000091401   ⟸   ENSRNOT00000116880
RefSeq Acc Id: NP_001386104   ⟸   NM_001399175
- UniProtKB: A0A8I5ZYE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118387   ⟸   XM_063262317
- Peptide Label: isoform X7
Protein Domains
RecA family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTF1-F1-model_v2 AlphaFold A0A0G2JTF1 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560681 AgrOrtholog
BioCyc Gene G2FUF-36967 BioCyc
Ensembl Genes ENSRNOG00000059245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000087132.2 UniProtKB/TrEMBL
  ENSRNOT00000105193 ENTREZGENE
  ENSRNOT00000105193.1 UniProtKB/TrEMBL
  ENSRNOT00000116880.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb/repair_RecA-like UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RAD51B UniProtKB/TrEMBL
  RecA_ATP-bd UniProtKB/TrEMBL
KEGG Report rno:500679 UniProtKB/TrEMBL
NCBI Gene 500679 ENTREZGENE
PANTHER DNA REPAIR PROTEIN RAD51 HOMOLOG 2 UniProtKB/TrEMBL
  PTHR46456 UniProtKB/TrEMBL
Pfam Rad51 UniProtKB/TrEMBL
PhenoGen Rad51b PhenoGen
PIRSF Rad51 UniProtKB/TrEMBL
PROSITE RECA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059245 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JTF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYE0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFI5 ENTREZGENE, UniProtKB/TrEMBL
  A6HCH3 ENTREZGENE, UniProtKB/TrEMBL
  A6HCH4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-23 Rad51b  RAD51 paralog B  Rad51b  RAD51 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Rad51b  RAD51 homolog B (S. cerevisiae)  Rad51l1  RAD51-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-28 Rad51l1  RAD51-like 1 (S. cerevisiae)  RGD1560681_predicted  similar to RAD51-like 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560681_predicted  similar to RAD51-like 1 (predicted)  LOC500679  similar to RAD51-like 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500679  similar to RAD51-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL