Rad51b (RAD51 paralog B) - Rat Genome Database

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Gene: Rad51b (RAD51 paralog B) Heterocephalus glaber
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Symbol: Rad51b
Name: RAD51 paralog B
RGD ID: 18908602
Description: ENCODES a protein that exhibits four-way junction DNA binding (ortholog); INVOLVED IN blastocyst growth (ortholog); in utero embryonic development (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH Breast Cancer, Familial (ortholog); Breast Neoplasms (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN Rad51B-Rad51C-Rad51D-XRCC2 complex (inferred); replication fork (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA repair protein RAD51 homolog 2; RAD51 homolog B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473432,560,579 - 33,173,357 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rad51b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473432,560,579 - 33,173,357 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RAD51B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,819,779 - 68,683,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,819,779 - 68,730,218 (+)EnsemblGRCh38hg38GRCh38
GRCh371468,286,496 - 69,149,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,356,262 - 68,132,367 (+)NCBINCBI36Build 36hg18NCBI36
Build 341467,356,261 - 68,014,562NCBI
Celera1448,345,516 - 49,121,494 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1448,455,813 - 49,231,230 (+)NCBIHuRef
CHM1_11468,225,211 - 69,001,135 (+)NCBICHM1_1
T2T-CHM13v2.01462,026,883 - 62,889,971 (+)NCBIT2T-CHM13v2.0
Rad51b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391279,344,032 - 79,895,034 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1279,344,056 - 79,861,464 (+)EnsemblGRCm39 Ensembl
GRCm381279,297,282 - 79,848,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1279,297,282 - 79,814,690 (+)EnsemblGRCm38mm10GRCm38
MGSCv371280,398,269 - 80,915,677 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361280,216,122 - 80,733,530 (+)NCBIMGSCv36mm8
Celera1280,761,261 - 81,278,996 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Rad51b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,829,390 - 104,373,923 (+)NCBIGRCr8
mRatBN7.2698,096,525 - 98,640,988 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,525,988 - 99,062,959 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,825,134 - 99,362,047 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,211,622 - 98,750,469 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,473,978 - 103,018,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,160,014 - 115,699,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46102,069,799 - 102,134,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera696,481,576 - 97,009,269 (+)NCBICelera
Cytogenetic Map6q24NCBI
Rad51b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,137,192 - 2,381,450 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554661,686,472 - 2,388,146 (-)NCBIChiLan1.0ChiLan1.0
RAD51B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,926,972 - 69,844,939 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11468,145,747 - 69,061,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01448,399,345 - 49,314,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11467,277,400 - 68,189,780 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1467,281,148 - 68,110,693 (+)Ensemblpanpan1.1panPan2
RAD51B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,779,435 - 42,357,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,778,714 - 42,357,298 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha841,469,217 - 42,151,951 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0842,009,371 - 42,691,934 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl842,009,155 - 42,586,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,624,025 - 42,306,963 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,699,024 - 42,381,539 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0842,056,861 - 42,740,806 (+)NCBIUU_Cfam_GSD_1.0
Rad51b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864062,431,048 - 62,999,072 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649511,195,767 - 11,467,458 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649511,185,560 - 11,762,254 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD51B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl791,592,424 - 92,345,294 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1791,592,413 - 92,301,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2797,899,832 - 98,613,557 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAD51B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12445,056,485 - 45,704,394 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605333,285,609 - 34,057,636 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004837341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002390446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01009973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01009993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01002220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_004837341   ⟹   XP_004837398
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473432,560,579 - 33,173,357 (-)NCBI
RefSeq Acc Id: XM_021247382   ⟹   XP_021103041
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473432,560,579 - 33,173,267 (-)NCBI
RefSeq Acc Id: XM_021247387   ⟹   XP_021103046
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473432,560,579 - 33,173,317 (-)NCBI
RefSeq Acc Id: XM_021247392   ⟹   XP_021103051
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473432,772,819 - 33,173,273 (-)NCBI
RefSeq Acc Id: XR_002390446
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473432,560,579 - 33,173,273 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004837398 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103041 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103046 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103051 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023260
GenBank Protein JAO01413 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004837398   ⟸   XM_004837341
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JX33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103046   ⟸   XM_021247387
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021103041   ⟸   XM_021247382
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021103051   ⟸   XM_021247392
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016581 ENTREZGENE
Ensembl Transcript ENSHGLT00000023476 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb/repair_RecA-like UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RAD51B UniProtKB/TrEMBL
  RecA_ATP-bd UniProtKB/TrEMBL
KEGG Report hgl:101714221 UniProtKB/TrEMBL
NCBI Gene Rad51b ENTREZGENE
PANTHER DNA REPAIR PROTEIN RAD51 HOMOLOG 2 UniProtKB/TrEMBL
  PTHR46456 UniProtKB/TrEMBL
Pfam Rad51 UniProtKB/TrEMBL
PIRSF Rad51 UniProtKB/TrEMBL
PROSITE RECA_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6JX33 ENTREZGENE, UniProtKB/TrEMBL