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Gene: Prrt1 (proline-rich transmembrane protein 1) Rattus norvegicus

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Symbol:

Prrt1

Name:

proline-rich transmembrane protein 1

RGD ID:

1359348

Description:

Predicted to enable identical protein binding activity and signaling receptor regulator activity. Predicted to be involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA receptor activity. Predicted to act upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Is active in glutamatergic synapse and postsynaptic membrane. Orthologous to human PRRT1 (proline rich transmembrane protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

dispanin subfamily D member 1; DSPD1; MGC109407; Ng5; Orf31; synapse differentiation-induced protein 4; SynDIG4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	4,122,565 - 4,126,386 (-)	NCBI		GRCr8
mRatBN7.2	20	4,117,957 - 4,121,643 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	4,117,957 - 4,121,600 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,824,462 - 4,828,125 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	4,186,221 - 4,189,878 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,717,120 - 4,720,786 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	4,392,605 - 4,396,271 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	4,392,626 - 4,396,250 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	6,471,963 - 6,475,627 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	4,219,837 - 4,223,478 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	4,220,084 - 4,221,821 (-)	NCBI
Celera	20	3,908,661 - 3,912,304 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Prrt1	Rat	proteasome-associated autoinflammatory syndrome 1		ISO	PRRT1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Prrt1	Rat	1,2-dichloroethane	increases expression	ISO	Prrt1 (Mus musculus)	6480464	ethylene dichloride results in increased expression of PRRT1 mRNA	CTD	PMID:28189721 and PMID:28960355
Prrt1	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Prrt1 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of PRRT1 mRNA	CTD	PMID:22206623
Prrt1	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of PRRT1 mRNA]	CTD	PMID:22206623
Prrt1	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of PRRT1 mRNA	CTD	PMID:22808131
Prrt1	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of PRRT1 mRNA	CTD	PMID:27913140
Prrt1	Rat	3,4-methylenedioxymethamphetamine	increases expression	ISO	Prrt1 (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PRRT1 mRNA	CTD	PMID:20188158
Prrt1	Rat	4,4'-sulfonyldiphenol	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PRRT1 mRNA	CTD	PMID:36041667
Prrt1	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of PRRT1 mRNA	CTD	PMID:24780913 and PMID:30047161
Prrt1	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of PRRT1 mRNA	CTD	PMID:31881176
Prrt1	Rat	all-trans-retinoic acid	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	Tretinoin results in decreased expression of PRRT1 mRNA	CTD	PMID:33167477
Prrt1	Rat	amitrole	decreases expression	EXP		6480464	Amitrole results in decreased expression of PRRT1 mRNA	CTD	PMID:30047161
Prrt1	Rat	aristolochic acid A	increases expression	ISO	PRRT1 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of PRRT1 mRNA	CTD	PMID:33212167
Prrt1	Rat	arsane	affects methylation	ISO	PRRT1 (Homo sapiens)	6480464	Arsenic affects the methylation of PRRT1 gene	CTD	PMID:25304211
Prrt1	Rat	arsenic atom	affects methylation	ISO	PRRT1 (Homo sapiens)	6480464	Arsenic affects the methylation of PRRT1 gene	CTD	PMID:25304211
Prrt1	Rat	atrazine	increases expression	EXP		6480464	Atrazine results in increased expression of PRRT1 mRNA	CTD	PMID:36841081
Prrt1	Rat	benzo[a]pyrene	increases expression	ISO	PRRT1 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased expression of PRRT1 mRNA	CTD	PMID:22316170
Prrt1	Rat	benzo[a]pyrene	affects methylation	ISO	PRRT1 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of PRRT1 3' UTR	CTD	PMID:27901495
Prrt1	Rat	beta-lapachone	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	beta-lapachone results in decreased expression of PRRT1 mRNA	CTD	PMID:38218311
Prrt1	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of PRRT1 mRNA	CTD	PMID:25181051 and PMID:30816183
Prrt1	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PRRT1 mRNA	CTD	PMID:36041667
Prrt1	Rat	bisphenol A	decreases expression	ISO	Prrt1 (Mus musculus)	6480464	bisphenol A results in decreased expression of PRRT1 mRNA	CTD	PMID:38074096
Prrt1	Rat	bisphenol F	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PRRT1 mRNA	CTD	PMID:36041667
Prrt1	Rat	bisphenol F	decreases expression	ISO	Prrt1 (Mus musculus)	6480464	bisphenol F results in decreased expression of PRRT1 mRNA	CTD	PMID:38685157
Prrt1	Rat	buta-1,3-diene	decreases expression	ISO	Prrt1 (Mus musculus)	6480464	1 and 3-butadiene results in decreased expression of PRRT1 mRNA	CTD	PMID:29038090
Prrt1	Rat	cadmium dichloride	decreases methylation	EXP		6480464	Cadmium Chloride results in decreased methylation of PRRT1 promoter	CTD	PMID:22457795
Prrt1	Rat	camptothecin	increases expression	ISO	PRRT1 (Homo sapiens)	6480464	Camptothecin results in increased expression of PRRT1 mRNA	CTD	PMID:38460933
Prrt1	Rat	chlorpyrifos	increases expression	ISO	Prrt1 (Mus musculus)	6480464	Chlorpyrifos results in increased expression of PRRT1 mRNA	CTD	PMID:37019170
Prrt1	Rat	cocaine	affects expression	EXP		6480464	Cocaine affects the expression of PRRT1 mRNA	CTD	PMID:20187946
Prrt1	Rat	copper atom	increases expression	EXP		6480464	Copper deficiency results in increased expression of PRRT1 mRNA	CTD	PMID:26033743
Prrt1	Rat	copper(0)	increases expression	EXP		6480464	Copper deficiency results in increased expression of PRRT1 mRNA	CTD	PMID:26033743
Prrt1	Rat	diuron	decreases expression	EXP		6480464	Diuron results in decreased expression of PRRT1 mRNA	CTD	PMID:21551480
Prrt1	Rat	dorsomorphin	multiple interactions	ISO	PRRT1 (Homo sapiens)	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRT1 mRNA	CTD	PMID:27188386
Prrt1	Rat	entinostat	increases expression	ISO	PRRT1 (Homo sapiens)	6480464	entinostat results in increased expression of PRRT1 mRNA	CTD	PMID:27188386
Prrt1	Rat	ethanol	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	Ethanol affects the expression of and affects the splicing of PRRT1 mRNA	CTD	PMID:30319688
Prrt1	Rat	ethylparaben	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	ethyl-p-hydroxybenzoate results in decreased expression of PRRT1 mRNA	CTD	PMID:37690743
Prrt1	Rat	fenvalerate	increases expression	EXP		6480464	fenvalerate results in increased expression of PRRT1 mRNA	CTD	PMID:30307764
Prrt1	Rat	folic acid	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of PRRT1 mRNA]	CTD	PMID:22206623
Prrt1	Rat	folic acid	increases expression	ISO	Prrt1 (Mus musculus)	6480464	Folic Acid results in increased expression of PRRT1 mRNA	CTD	PMID:25629700
Prrt1	Rat	folic acid	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	Folic Acid results in decreased expression of PRRT1 mRNA	CTD	PMID:21867686
Prrt1	Rat	fonofos	increases methylation	ISO	PRRT1 (Homo sapiens)	6480464	Fonofos results in increased methylation of PRRT1 promoter	CTD	PMID:22847954
Prrt1	Rat	furan	increases expression	EXP		6480464	furan results in increased expression of PRRT1 mRNA	CTD	PMID:27387713
Prrt1	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of PRRT1 mRNA	CTD	PMID:22061828 and PMID:33387578
Prrt1	Rat	iron dichloride	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	ferrous chloride results in decreased expression of PRRT1 mRNA	CTD	PMID:35984750
Prrt1	Rat	lead diacetate	affects expression	EXP		6480464	lead acetate affects the expression of PRRT1 protein	CTD	PMID:36539177
Prrt1	Rat	lead(0)	affects expression	ISO	PRRT1 (Homo sapiens)	6480464	Lead affects the expression of PRRT1 mRNA	CTD	PMID:28903495
Prrt1	Rat	maneb	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	[Maneb co-treated with Paraquat] results in increased expression of PRRT1 mRNA	CTD	PMID:36117858
Prrt1	Rat	methimazole	decreases expression	EXP		6480464	Methimazole results in decreased expression of PRRT1 mRNA	CTD	PMID:30047161
Prrt1	Rat	O-methyleugenol	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	methyleugenol results in decreased expression of PRRT1 mRNA	CTD	PMID:32234424
Prrt1	Rat	paracetamol	affects expression	ISO	Prrt1 (Mus musculus)	6480464	Acetaminophen affects the expression of PRRT1 mRNA	CTD	PMID:17562736
Prrt1	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of PRRT1 mRNA	CTD	PMID:33387578
Prrt1	Rat	paraquat	decreases expression	ISO	Prrt1 (Mus musculus)	6480464	Paraquat results in decreased expression of PRRT1 mRNA	CTD	PMID:22563483
Prrt1	Rat	paraquat	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	[Maneb co-treated with Paraquat] results in increased expression of PRRT1 mRNA	CTD	PMID:36117858
Prrt1	Rat	parathion	increases methylation	ISO	PRRT1 (Homo sapiens)	6480464	Parathion results in increased methylation of PRRT1 promoter	CTD	PMID:22847954
Prrt1	Rat	pirinixic acid	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PRRT1 mRNA	CTD	PMID:19710929
Prrt1	Rat	quercetin	increases expression	ISO	PRRT1 (Homo sapiens)	6480464	Quercetin results in increased expression of PRRT1 mRNA	CTD	PMID:21632981
Prrt1	Rat	resveratrol	multiple interactions	ISO	PRRT1 (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of PRRT1 mRNA	CTD	PMID:23557933
Prrt1	Rat	SB 431542	multiple interactions	ISO	PRRT1 (Homo sapiens)	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRT1 mRNA	CTD	PMID:27188386
Prrt1	Rat	sodium arsenite	decreases expression	ISO	Prrt1 (Mus musculus)	6480464	sodium arsenite results in decreased expression of PRRT1 mRNA	CTD	PMID:37682722
Prrt1	Rat	succimer	multiple interactions	ISO	Prrt1 (Mus musculus)	6480464	[Succimer binds to Magnetite Nanoparticles] which results in increased expression of PRRT1 mRNA	CTD	PMID:21641980
Prrt1	Rat	terbufos	increases methylation	ISO	PRRT1 (Homo sapiens)	6480464	terbufos results in increased methylation of PRRT1 promoter	CTD	PMID:22847954
Prrt1	Rat	testosterone	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	Testosterone results in decreased expression of PRRT1 mRNA	CTD	PMID:33359661
Prrt1	Rat	thimerosal	decreases expression	ISO	PRRT1 (Homo sapiens)	6480464	Thimerosal results in decreased expression of PRRT1 mRNA	CTD	PMID:27188386
Prrt1	Rat	titanium dioxide	decreases methylation	ISO	Prrt1 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of PRRT1 enhancer and titanium dioxide results in decreased methylation of PRRT1 gene	CTD	PMID:35295148
Prrt1	Rat	triptonide	increases expression	ISO	Prrt1 (Mus musculus)	6480464	triptonide results in increased expression of PRRT1 mRNA	CTD	PMID:33045310
Prrt1	Rat	tris(2-butoxyethyl) phosphate	affects expression	ISO	PRRT1 (Homo sapiens)	6480464	tris(2-butoxyethyl) phosphate affects the expression of PRRT1 mRNA	CTD	PMID:29024780
Prrt1	Rat	valproic acid	increases expression	ISO	PRRT1 (Homo sapiens)	6480464	Valproic Acid results in increased expression of PRRT1 mRNA	CTD	PMID:23179753
Prrt1	Rat	valproic acid	multiple interactions	ISO	PRRT1 (Homo sapiens)	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRT1 mRNA	CTD	PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Prrt1	Rat	learning or memory	acts_upstream_of_or_within	ISO	Prrt1 (Mus musculus)	1624291	MGI:3812714 PMID:29490264	RGD	PMID:29490264
Prrt1	Rat	long-term synaptic depression	involved_in	ISS	UniProtKB:O35449	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Prrt1	Rat	long-term synaptic depression	involved_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:31216424	RGD	PMID:31216424
Prrt1	Rat	long-term synaptic potentiation	acts_upstream_of_or_within	ISO	Prrt1 (Mus musculus)	1624291	MGI:3812714 PMID:29490264	RGD	PMID:29490264
Prrt1	Rat	protein localization	acts_upstream_of_or_within	ISO	Prrt1 (Mus musculus)	1624291	MGI:3812714 PMID:29490264	RGD	PMID:29490264
Prrt1	Rat	protein localization to cell surface	involved_in	ISS	UniProtKB:O35449	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Prrt1	Rat	protein localization to cell surface	involved_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:31216424	RGD	PMID:31216424
Prrt1	Rat	protein phosphorylation	involved_in	ISS	UniProtKB:O35449	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Prrt1	Rat	protein phosphorylation	involved_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:31216424	RGD	PMID:31216424
Prrt1	Rat	regulation of AMPA receptor activity	involved_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:29490264 and PMID:31216424	RGD	PMID:29490264 and PMID:31216424
Prrt1	Rat	regulation of AMPA receptor activity	involved_in	ISS	UniProtKB:O35449	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Prrt1	Rat	synapse organization	acts_upstream_of_or_within	ISO	Prrt1 (Mus musculus)	1624291	MGI:3812714 PMID:29490264	RGD	PMID:29490264

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Prrt1	Rat	glutamatergic synapse	is_active_in	IDA		13702344	PMID:26660156	SynGO
Prrt1	Rat	glutamatergic synapse	is_active_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:36429079	RGD	PMID:36429079
Prrt1	Rat	glutamatergic synapse	is_active_in	IEP		13702344	PMID:26660156	SynGO
Prrt1	Rat	membrane	is_active_in	IBA	MGI:1916267 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Prrt1	Rat	membrane	located_in	IEA	InterPro:IPR007593	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Prrt1	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Prrt1	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Prrt1	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Prrt1	Rat	postsynaptic density membrane	located_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:29490264	RGD	PMID:29490264
Prrt1	Rat	postsynaptic density membrane	is_active_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:36429079	RGD	PMID:36429079
Prrt1	Rat	postsynaptic membrane	is_active_in	IDA		13702344	PMID:26660156	SynGO
Prrt1	Rat	postsynaptic membrane	is_active_in	IEP		13702344	PMID:26660156	SynGO
Prrt1	Rat	synapse	located_in	IEA	UniProtKB-SubCell:SL-0258	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Prrt1	Rat	synapse	located_in	IEA	UniProtKB-KW:KW-0770	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Prrt1	Rat	synaptic vesicle membrane	located_in	ISO	Prrt1 (Mus musculus)	1624291	PMID:29490264	RGD	PMID:29490264

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Prrt1	Rat	identical protein binding	enables	ISO	PRRT1 (Homo sapiens) and UniProtKB:Q99946-2	1624291	UniProtKB:Q99946-2 and PMID:32296183	RGD	PMID:32296183
Prrt1	Rat	protein binding	enables	ISO	PRRT1 (Homo sapiens) and UniProtKB:Q99946-2	1624291	UniProtKB:P21145 and PMID:32296183	RGD	PMID:32296183
Prrt1	Rat	signaling receptor regulator activity	enables	ISO	Prrt1 (Mus musculus)	1624291	PMID:29490264	RGD	PMID:29490264

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Distribution of the SynDIG4/proline-rich transmembrane protein 1 in rat brain.	Kirk LM, etal., J Comp Neurol. 2016 Aug 1;524(11):2266-80. doi: 10.1002/cne.23945. Epub 2015 Dec 29.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12477932	PMID:29476059	PMID:29490264

Prrt1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	4,122,565 - 4,126,386 (-)	NCBI		GRCr8
mRatBN7.2	20	4,117,957 - 4,121,643 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	4,117,957 - 4,121,600 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,824,462 - 4,828,125 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	4,186,221 - 4,189,878 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,717,120 - 4,720,786 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	4,392,605 - 4,396,271 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	4,392,626 - 4,396,250 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	6,471,963 - 6,475,627 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	4,219,837 - 4,223,478 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	4,220,084 - 4,221,821 (-)	NCBI
Celera	20	3,908,661 - 3,912,304 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

PRRT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	32,148,363 - 32,153,083 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	32,148,359 - 32,153,083 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	32,116,140 - 32,120,860 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	32,224,118 - 32,227,698 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	32,224,118 - 32,227,698	NCBI
Celera	6	33,683,181 - 33,686,760 (-)	NCBI		Celera
Cytogenetic Map	6	p21.32	NCBI
HuRef	6	31,870,129 - 31,873,708 (-)	NCBI		HuRef
CHM1_1	6	32,118,648 - 32,122,228 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	32,001,551 - 32,006,271 (-)	NCBI		T2T-CHM13v2.0

Prrt1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	34,848,396 - 34,852,108 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	34,848,507 - 34,852,100 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	34,629,365 - 34,633,134 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	34,629,533 - 34,633,126 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	34,766,631 - 34,769,205 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,237,742 - 34,240,316 (+)	NCBI		MGSCv36	mm8
Celera	17	37,724,859 - 37,727,433 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.21	NCBI

Prrt1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955437	614,026 - 615,177 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRRT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,610,947 - 46,615,698 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	42,572,421 - 42,578,339 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,795,267 - 31,798,873 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,675,369 - 32,678,954 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,675,369 - 32,679,109 (-)	Ensembl	panpan1.1		panPan2

PRRT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,545,384 - 1,549,015 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	1,542,789 - 1,548,964 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,679,075 - 1,682,732 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,683,596 - 1,687,254 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,683,600 - 1,687,212 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,546,622 - 1,550,273 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,612,248 - 1,615,897 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,678,547 - 1,682,198 (-)	NCBI		UU_Cfam_GSD_1.0

Prrt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	36,109,179 - 36,113,398 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,447,478 - 1,453,706 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,448,017 - 1,452,536 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRRT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	24,180,637 - 24,186,908 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	24,183,557 - 24,186,892 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	28,004,371 - 28,007,706 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRRT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	39,879,600 - 39,883,173 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	39,879,710 - 39,882,308 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	32,048,555 - 32,054,162 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prrt1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	24,164,871 - 24,168,614 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	24,165,085 - 24,168,614 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Prrt1
18 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	164
Count of miRNA genes:	113
Interacting mature miRNAs:	141
Transcripts:	ENSRNOT00000000495
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61472	Aia1	Adjuvant induced arthritis QTL 1	18	0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	2646395	4597031	Rat
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1527959	5304575	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26123605	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
61448	Ciaa1	CIA Autoantibody QTL 1	30	0.001	blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	20	2646395	4597031	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	20	3621649	10078919	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	3621649	9243559	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	14101050	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
737973	Pia21	Pristane induced arthritis QTL 21	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	4606812	Rat

RH131882

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	4,118,003 - 4,118,153 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	4,396,075 - 4,396,224	NCBI	Rnor6.0
Rnor_5.0	20	6,475,431 - 6,475,580	UniSTS	Rnor5.0
RGSC_v3.4	20	4,219,884 - 4,220,033	UniSTS	RGSC3.4
Celera	20	3,912,108 - 3,912,257	UniSTS
RH 3.4 Map	20	53.02	UniSTS
Cytogenetic Map	20	p12	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001032285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC089986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000000495 ⟹ ENSRNOP00000000495

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	4,117,957 - 4,121,600 (-)	Ensembl
Rnor_6.0 Ensembl	20	4,392,626 - 4,396,243 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	4,118,041 - 4,121,600 (-)	Ensembl
Rnor_6.0 Ensembl	20	4,394,514 - 4,396,250 (+)	Ensembl

RefSeq Acc Id:

NM_001032285 ⟹ NP_001027456

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	4,122,565 - 4,126,213 (-)	NCBI
mRatBN7.2	20	4,117,957 - 4,121,605 (-)	NCBI
Rnor_6.0	20	4,392,626 - 4,396,271 (+)	NCBI
Rnor_5.0	20	6,471,963 - 6,475,627 (+)	NCBI
RGSC_v3.4	20	4,219,837 - 4,223,478 (-)	RGD
Celera	20	3,908,661 - 3,912,304 (+)	RGD

Sequence:

show sequence

CTCGCTGCTGCTGCTGCTACCGCCGCTGCACCGGCTGCGCCATCCGGGACTCAGACTCCTGCGCCAGCAGTCAGGGGGCCCTGACTCTAGCTTCAGAGACCCTGTTCCAGCGCTTGCGAGCATGTCGT
CAGAAAAGTCAGGCCTTCCAGACTCGGTTCCCCACACTTCACCTCCGCCCTACAATGCCCCCCAACCTCCAGCCGAGCCCCCCATCCCTCCCCCACAAACCGCTCCATCCTCTCATCATCATCACCAC
CACCACTACCACCAGTCTGGCACTGCCACCCTCCCGCGCTTAGGAGCAGGTGGCCTGGCCTCTGCTGCGGCTGGCGCTCAACGTGGTCCTTCGTCCTCTGCCACGCTACCGCGGCCCCCCCACCATGC
CCCTCCCGGTCCCGCTGCTGGGGCTCCCCCACCCGGCTGTGCTACCCTACCCCGCATGCCACCCGACCCTTATCTGCAGGAGACTCGCTTCGAGGGTCCACTTCCCCCACCACCGCCTGCGGCCGCCG
CCCCACCCCCACCAGCGCCTGCCCCGACGGCCCAAGCCCCAGGCTTCGTGGTGCCCACGCACGCGGGGGCGGTGGGCACGTTGCCGCTGGGGGGCTACGTGGCTCCGGGCTACCCGCTGCAGCTGCAG
CCGTGCACCGCTTATGTCCCGGTGTATCCGGTGGGCACGCCCTACGCAAGCGGGACCCCCGGGGGTCCAGGAGTGACCTCCACTCTGCCCCCGCCGCCCCAGGGCCCAGGGTTGGCTCTGTTGGAGCC
CAGGCGCCCGCCGCATGACTACATGCCCATCGCTGTGCTGACCACCATCTGCTGCTTCTGGCCCACAGGCATCATCGCCATCTTCAAGGCCGTGCAGGTGCGCACGGCCTTGGCCCGCGGAGACTTGG
TGTCCGCCGAGATCGCTTCGCGCGAGGCCCGGAATTTCTCCTTCATCTCCCTGGCCGTGGGCATCGCAGCTATGGTGCTTTGTACCATCCTCACTGTAGTCATCATCATTGCCGCCCAGCACCACGAA
AACTACTGGGATCCCTAAAAACGTCCCCGTCTCGGCCCCGCTCCGTGCCCCCTCCCAACCTCCCAGGCGCGTGGCGCAGTCCTGCCGCCTACCCAGAGCGCGCCCTGCACATCCTCCTGAGGCGCCGC
TGGACTTCCAGACATCATAAACTCCGCCCCCACGGAACCTCTGGCCCAGAGAGTACGCTCAGTTCCTCAGGAACCCCTCTAGCACCCACATCCTCAGCGGCACTGGAATCCGCGCCAAACCCCGACCC
TCCAGTCGCCCCAATTCCCCACCCCATCAAAGTGCAGTGCCAGCCAGGGGCGGATCTCTCCTGCTCTCCGCTCCCCAGTAGGGAGTCAGGTCCCAGAAGCTCCGCCTCATCTATAAGCTCCGCCCCAA
ATCCCACAAACCCCGCCTCCAGGTCGGCAGGCTCCGCCTTCTTTTCTTCTTTGGGGTTTTTCAGTCTGGTGATTGGGTCTGTGAATCCAGGCCCCCAGCCCACAATACAGACGGACTAGTCCCCCTAC
CTCCCTAAAAGGACTCAGCCCTGGGAGAACTACACCCCCACTCTAGCTCGGATTTTTGCCAGTGCGGATTTTTCTCCCCGCCCCCAACCCCCATCTCTGCCTATTTTCTTGCTAATTACAGAACTTCC
CATTTTGCGGCTTTTGGAGTGAGATGAGGCAAGTTCCAGGTTTAGTACCCCTCACTCTGGAAAGAGAACCAAGTCCCTATAATGTAAATACCCTTTCTACATGTGCCAACCCCTGGGCAGCGGGGGCA
GAAGAGAATCCAGGGTTAAAGGGAGGGAGTCGACGCTCCCCCGCTCCCCTCTGCCCTAGACTTGTTTTGATCTGTGTGTGCCAGTGTGTGTGAACTTCTGAAAGACAGTATTAAAGACATTTTAGTGG
ATTTATCACCCGCAGTTCCAAAGACCACA

hide sequence

RefSeq Acc Id:

XM_006255980 ⟹ XP_006256042

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	4,122,586 - 4,126,020 (-)	NCBI
mRatBN7.2	20	4,117,972 - 4,121,389 (-)	NCBI
Rnor_6.0	20	4,392,837 - 4,396,256 (+)	NCBI
Rnor_5.0	20	6,471,963 - 6,475,627 (+)	NCBI

Sequence:

show sequence

TATATATATATATATTCCCCACCCCTATCAACCCCTACCTAACCCCCACTTGCCCCAGTCCCCT
TCTTTGACCCCCTCTGGGTGTAGTGTGTGGCTCAGTTCCATTCCCCTTCTCTCCGTGCATACCCCCCACCCCTCCCCTTTCTATATTCCATCCTCCTTCCTTAGGGTCAGTCTGCCTCCGTCCCTTGT
CAACAACATTGGTGGGGGGGGCAGTTTAGAAAAGGAAAGGGAGGCACAGTCAGGTACTGCAGGGACAACATCCCTGGGGGTGACAGATGGACAGTCACCGGTTCACTGGCATGGAGACACCCAGTGGA
AAAATTACGGAGACTTGATCAGACGGGGTTGTTGGGAAAGTAGTATCTAGAAGATTCCTCTTTATTGAGATGAGATTTCCCTATGTAGCCCAGGCGGGTCTTGAACTTCCTCCTGTTCTTCACCCTTC
TGCCTCTGCTTCACAAATACTAGGATTGAAGGCATGAGCCACCATGCCTAGCCCCAGGAGCTCTGTTATGGGCCTTAACCGAGGCCATGAGATCCCCAGGTAACTCCGACCTGACGCAAAGCGGAAAT
GTTAAACTGAGCGTTCATGCCCCTGTGACACGGCCACATGTGCTGGGAGAGGAGCAGCTCAGACGGCCCTGGAAGAGGGTTGTGGTTGACAGCAGGGGAACCTGGGAGGAGTTGTGACAGTTGTGACG
GCAAAACTAGAACTGGGGCCAGGTGGCCTAGATACAACCCCTTCCCTGACCCCAAAATGGGAGATGTCGTCTCAGCTATCTCTCCCTCGCTATTTCTCCATCTCTTGCTGTCTCATGTCTCTTACCCT
TCTGATCTCTGCTGTCTTCTCTCTCCCCTTATTCTCTCCTCGGCTTTTCCATGGCCAGGCCTTCCAGACTCGGTTCCCCACACTTCACCTCCGCCCTACAATGCCCCCCAACCTCCAGCCGAGCCCCC
CATCCCTCCCCCACAAACCGCTCCATCCTCTCATCATCATCACCACCACCACTACCACCAGTCTGGCACTGCCACCCTCCCGCGCTTAGGAGCAGGTGGCCTGGCCTCTGCTGCGGCTGGCGCTCAAC
GTGGTCCTTCGTCCTCTGCCACGCTACCGCGGCCCCCCCACCATGCCCCTCCCGGTCCCGCTGCTGGGGCTCCCCCACCCGGCTGTGCTACCCTACCCCGCATGCCACCCGACCCTTATCTGCAGGAG
ACTCGCTTCGAGGGTCCACTTCCCCCACCACCGCCTGCGGCCGCCGCCCCACCCCCACCAGCGCCTGCCCCGACGGCCCAAGCCCCAGGCTTCGTGGTGCCCACGCACGCGGGGGCGGTGGGCACGTT
GCCGCTGGGGGGCTACGTGGCTCCGGGCTACCCGCTGCAGCTGCAGCCGTGCACCGCTTATGTCCCGGTGTATCCGGTGGGCACGCCCTACGCAAGCGGGACCCCCGGGGGTCCAGGAGTGACCTCCA
CTCTGCCCCCGCCGCCCCAGGGCCCAGGGTTGGCTCTGTTGGAGCCCAGGCGCCCGCCGCATGACTACATGCCCATCGCTGTGCTGACCACCATCTGCTGCTTCTGGCCCACAGGCATCATCGCCATC
TTCAAGGCCGTGCAGGTGCGCACGGCCTTGGCCCGCGGAGACTTGGTGTCCGCCGAGATCGCTTCGCGCGAGGCCCGGAATTTCTCCTTCATCTCCCTGGCCGTGGGCATCGCAGCTATGGTGCTTTG
TACCATCCTCACTGTAGTCATCATCATTGCCGCCCAGCACCACGAAAACTACTGGGATCCCTAAAAACGTCCCCGTCTCGGCCCCGCTCCGTGCCCCCTCCCAACCTCCCAGGCGCGTGGCGCAGTCC
TGCCGCCTACCCAGAGCGCGCCCTGCACATCCTCCTGAGGCGCCGCTGGACTTCCAGACATCATAAACTCCGCCCCCACGGAACCTCTGGCCCAGAGAGTACGCTCAGTTCCTCAGGAACCCCTCTAG
CACCCACATCCTCAGCGGCACTGGAATCCGCGCCAAACCCCGACCCTCCAGTCGCCCCAATTCCCCACCCCATCAAAGTGCAGTGCCAGCCAGGGGCGGATCTCTCCTGCTCTCCGCTCCCCAGTAGG
GAGTCAGGTCCCAGAAGCTCCGCCTCATCTATAAGCTCCGCCCCAAATCCCACAAACCCCGCCTCCAGGTCGGCAGGCTCCGCCTTCTTTTCTTCTTTGGGGTTTTTCAGTCTGGTGATTGGGTCTGT
GAATCCAGGCCCCCAGCCCACAATACAGACGGACTAGTCCCCCTACCTCCCTAAAAGGACTCAGCCCTGGGAGAACTACACCCCCACTCTAGCTCGGATTTTTGCCAGTGCGGATTTTTCTCCCCGCC
CCCAACCCCCATCTCTGCCTATTTTCTTGCTAATTACAGAACTTCCCATTTTGCGGCTTTTGGAGTGAGATGAGGCAAGTTCCAGGTTTAGTACCCCTCACTCTGGAAAGAGAACCAAGTCCCTATAA
TGTAAATACCCTTTCTACATGTGCCAACCCCTGGGCAGCGGGGGCAGAAGAGAATCCAGGGTTAAAGGGAGGGAGTCGACGCTCCCCCGCTCCCCTCTGCCCTAGACTTGTTTTGATCTGTGTGTGCC
AGTGTGTGTGAACTTCTGAAAGACAGTATTAAAGACATTTTAGTGGATTTATCACCCGCA

hide sequence

RefSeq Acc Id:

XM_006255981 ⟹ XP_006256043

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	4,123,871 - 4,126,386 (-)	NCBI
mRatBN7.2	20	4,119,256 - 4,121,643 (-)	NCBI
Rnor_6.0	20	4,392,605 - 4,394,955 (+)	NCBI
Rnor_5.0	20	6,471,963 - 6,475,627 (+)	NCBI

Sequence:

show sequence

CTGTCTTCATCTCTCCATTTCCTCGCTGCTGCTGCTGCTACCGCCGCTGCACCGGCTGCGCCAT
CCGGGACTCAGACTCCTGCGCCAGCAGTCAGGGGGCCCTGACTCTAGCTTCAGAGACCCTGTTCCAGCGCTTGCGAGCATGTCGTCAGAAAAGTCAGGCCTTCCAGACTCGGTTCCCCACACTTCACC
TCCGCCCTACAATGCCCCCCAACCTCCAGCCGAGCCCCCCATCCCTCCCCCACAAACCGCTCCATCCTCTCATCATCATCACCACCACCACTACCACCAGTCTGGCACTGCCACCCTCCCGCGCTTAG
GAGCAGGTGGCCTGGCCTCTGCTGCGGCTGGCGCTCAACGTGGTCCTTCGTCCTCTGCCACGCTACCGCGGCCCCCCCACCATGCCCCTCCCGGTCCCGCTGCTGGGGCTCCCCCACCCGGCTGTGCT
ACCCTACCCCGCATGCCACCCGACCCTTATCTGCAGGAGACTCGCTTCGAGGGTCCACTTCCCCCACCACCGCCTGCGGCCGCCGCCCCACCCCCACCAGCGCCTGCCCCGACGGCCCAAGCCCCAGG
CTTCGTGGTGCCCACGCACGCGGGGGCGGTGGGCACGTTGCCGCTGGGGGGCTACGTGGCTCCGGGCTACCCGCTGCAGCTGCAGCCGTGCACCGCTTATGTCCCGGTGTATCCGGTGGGCACGGTGA
GTATGGGGCTGACAGGACCTAGGAGGACAGGGAGGCAGGTGCAACAGGGACGCACACACTCTGGAAGCTGGGAGAGAGTGAAACAGAACCAGGCTGTCCGCCCTTCTGGTAACAAACCCTGGACAGAA
GAGTGGAGAGAGGAGAGACAATGGGTGGGAAAGTGGTGGACCTTGGGGGGAAGCGGGGAGGAGTCTGGGGGATCAAAGGTCAAGGTTTGGGCCGTGGTTCAGAAATCAGTTGGTCTGAAAGAAGGAAA
ACAGCTTGGAGGGAGAGAGAGAGATGGAACCTGGGAAGCCAGGGGTAAAAGAGGGCAGAAGCCTGGGCCTGGAGATGCTAAGGAAGATGGAAACAAGACCGGAAGGACAGACAGACCCATAAGCCATA
CCTTGTAGGACACTGTGGGAACTTCCCCGAATATTCAAGTTAATGATACGTGAAGAGAGGCCTAGGCCGATTTTACTGTCAGGAACGATTTTTTTTTCCCCTTAAGCAAAATCGTGTTTTTAAAAACC
TCTTTGCCAATTGGCCAGCTGCTGGCAAGCAGCAAGACTGTTGGTGTGACGTCCCTTTCCCCCACTGTCCTTCCCACAGCCCTACGCAAGCGGGACCCCCGGGGGTCCAGGAGTGACCTCCACTCTGC
CCCCGCCGCCCCAGGGCCCAGGGTTGGCTCTGTTGGAGCCCAGGCG

hide sequence

RefSeq Acc Id:

XM_063279357 ⟹ XP_063135427

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	4,122,586 - 4,126,225 (-)	NCBI

RefSeq Acc Id:

XM_063279358 ⟹ XP_063135428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	4,122,586 - 4,126,242 (-)	NCBI


Protein RefSeqs	NP_001027456	(Get FASTA)	NCBI Sequence Viewer
	XP_006256042	(Get FASTA)	NCBI Sequence Viewer
	XP_006256043	(Get FASTA)	NCBI Sequence Viewer
	XP_063135427	(Get FASTA)	NCBI Sequence Viewer
	XP_063135428	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89986	(Get FASTA)	NCBI Sequence Viewer
	CAE83964	(Get FASTA)	NCBI Sequence Viewer
	EDL83419	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000000495
	ENSRNOP00000000495.4
	ENSRNOP00000085419.1
	ENSRNOP00000098032
GenBank Protein	Q6MG82	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001027456 ⟸ NM_001032285

- UniProtKB:

Q6MG82 (UniProtKB/Swiss-Prot), A6KTI9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPA
AAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYASGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARG
DLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP

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RefSeq Acc Id:	XP_006256043 ⟸ XM_006255981
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A292 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGL ASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTVSMGLT GPRRTGRQVQQGRTHSGSWERVKQNQAVRPSGNKPWTEEWREERQWVGKWWTLGGSGEESGGSKVKVWAVVQKSVGLKEGKQLGGRERDGTWEARGKRGQKPGPGDAKEDGNKTGRTDRPISHTL hide sequence

RefSeq Acc Id:

XP_006256042 ⟸ XM_006255980

- Peptide Label:

isoform X1

- Sequence:

show sequence

MCWERSSSDGPGRGLWLTAGEPGRSCDSCDGKTRTGARWPRYNPFPDPKMGDVVSAISPSLFLHLLLSHVSYPSDLCCLLSPLILSSAFPWPGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHH
HHHHHYHQSGTATLPRLGAGGLASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPL
QLQPCTAYVPVYPVGTPYASGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQ
HHENYWDP

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Ensembl Acc Id:

ENSRNOP00000000495 ⟸ ENSRNOT00000000495

RefSeq Acc Id:	XP_063135428 ⟸ XM_063279358
- Peptide Label:	isoform X3

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6MG82-F1-model_v2	AlphaFold	Q6MG82	1-306	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13701348

Promoter ID:

EPDNEW_R11871

Type:

initiation region

Name:

Prrt1_1

Description:

proline-rich transmembrane protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	4,392,625 - 4,392,685	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-4588	BioCyc
Ensembl Genes	ENSRNOG00000000433	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000495	ENTREZGENE
	ENSRNOT00000000495.7	UniProtKB/Swiss-Prot
	ENSRNOT00000091188.2	UniProtKB/TrEMBL
	ENSRNOT00000120342	ENTREZGENE
InterPro	CD225/Dispanin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CD225/Dispanin_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:406167	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	406167	ENTREZGENE
PANTHER	NG5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROLINE-RICH TRANSMEMBRANE PROTEIN 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	CD225	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Prrt1	PhenoGen
RatGTEx	ENSRNOG00000000433	RatGTEx
UniProt	A0A8I6A292	ENTREZGENE, UniProtKB/TrEMBL
	A6KTI9	ENTREZGENE, UniProtKB/TrEMBL
	PRRT1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-05-24	Prrt1	proline-rich transmembrane protein 1	LOC683953	similar to NG5 protein	Data merged from RGD:1596543	1643240	APPROVED
2008-03-06	Prrt1	proline-rich transmembrane protein 1	Ng5	NG5 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC683953	similar to NG5 protein			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-07-29	Ng5	NG5 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar