PRRT1 (proline rich transmembrane protein 1) - Rat Genome Database

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Gene: PRRT1 (proline rich transmembrane protein 1) Canis lupus familiaris
Analyze
Symbol: PRRT1
Name: proline rich transmembrane protein 1
RGD ID: 12141099
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN learning or memory (ortholog); long-term synaptic potentiation (ortholog); protein localization (ortholog); ASSOCIATED WITH genetic disease (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog); postsynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proline-rich transmembrane protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,545,384 - 1,549,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,542,789 - 1,548,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,679,075 - 1,682,732 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,683,596 - 1,687,254 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,683,600 - 1,687,212 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,546,622 - 1,550,273 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,612,248 - 1,615,897 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,678,547 - 1,682,198 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRRT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,545,384 - 1,549,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,542,789 - 1,548,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,679,075 - 1,682,732 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,683,596 - 1,687,254 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,683,600 - 1,687,212 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,546,622 - 1,550,273 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,612,248 - 1,615,897 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,678,547 - 1,682,198 (-)NCBIUU_Cfam_GSD_1.0
PRRT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,148,363 - 32,153,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,148,359 - 32,153,083 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,116,140 - 32,120,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,224,118 - 32,227,698 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,224,118 - 32,227,698NCBI
Celera633,683,181 - 33,686,760 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef631,870,129 - 31,873,708 (-)NCBIHuRef
CHM1_1632,118,648 - 32,122,228 (-)NCBICHM1_1
T2T-CHM13v2.0632,001,551 - 32,006,271 (-)NCBIT2T-CHM13v2.0
Prrt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,848,396 - 34,852,108 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,848,507 - 34,852,100 (+)EnsemblGRCm39 Ensembl
GRCm381734,629,365 - 34,633,134 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,629,533 - 34,633,126 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,766,631 - 34,769,205 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,237,742 - 34,240,316 (+)NCBIMGSCv36mm8
Celera1737,724,859 - 37,727,433 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.21NCBI
Prrt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,122,565 - 4,126,386 (-)NCBIGRCr8
mRatBN7.2204,117,957 - 4,121,643 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,117,957 - 4,121,600 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,824,462 - 4,828,125 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,186,221 - 4,189,878 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,717,120 - 4,720,786 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,392,605 - 4,396,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,392,626 - 4,396,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,471,963 - 6,475,627 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,219,837 - 4,223,478 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,220,084 - 4,221,821 (-)NCBI
Celera203,908,661 - 3,912,304 (+)NCBICelera
Cytogenetic Map20p12NCBI
Prrt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955437614,026 - 615,177 (-)NCBIChiLan1.0ChiLan1.0
PRRT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,610,947 - 46,615,698 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,572,421 - 42,578,339 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,795,267 - 31,798,873 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,675,369 - 32,678,954 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,675,369 - 32,679,109 (-)Ensemblpanpan1.1panPan2
Prrt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,109,179 - 36,113,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,447,478 - 1,453,706 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,448,017 - 1,452,536 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRRT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,180,637 - 24,186,908 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,183,557 - 24,186,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2728,004,371 - 28,007,706 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRRT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,879,600 - 39,883,173 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,879,710 - 39,882,308 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604432,048,555 - 32,054,162 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prrt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,164,871 - 24,168,614 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,165,085 - 24,168,614 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PRRT1
55 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 5 22 6 3 6 3 6 8 2
Below cutoff 5 3 3 6 7 2 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000001192   ⟹   ENSCAFP00000001091
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl121,542,789 - 1,548,964 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000078932   ⟹   ENSCAFP00000059058
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl121,542,789 - 1,548,207 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845026255   ⟹   ENSCAFP00845020698
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl121,683,600 - 1,687,212 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845026264   ⟹   ENSCAFP00845020705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl121,683,600 - 1,686,424 (-)Ensembl
RefSeq Acc Id: XM_038491399   ⟹   XP_038347327
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1121,546,622 - 1,550,273 (-)NCBI
RefSeq Acc Id: XM_038553616   ⟹   XP_038409544
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,678,547 - 1,682,198 (-)NCBI
RefSeq Acc Id: XM_038617492   ⟹   XP_038473420
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0121,612,248 - 1,615,897 (-)NCBI
RefSeq Acc Id: XM_038683080   ⟹   XP_038539008
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0121,683,596 - 1,687,254 (-)NCBI
RefSeq Acc Id: XM_844418   ⟹   XP_849511
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1121,545,384 - 1,549,015 (-)NCBI
Dog10K_Boxer_Tasha121,679,075 - 1,682,732 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_849511   ⟸   XM_844418
- UniProtKB: A0A8C0NNP5 (UniProtKB/TrEMBL),   A0A8I3RY99 (UniProtKB/TrEMBL),   A0A8C0T0L3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000059058   ⟸   ENSCAFT00000078932
RefSeq Acc Id: ENSCAFP00000001091   ⟸   ENSCAFT00000001192
RefSeq Acc Id: XP_038347327   ⟸   XM_038491399
RefSeq Acc Id: XP_038473420   ⟸   XM_038617492
RefSeq Acc Id: XP_038539008   ⟸   XM_038683080
- UniProtKB: A0A8C0NNP5 (UniProtKB/TrEMBL),   A0A8I3RY99 (UniProtKB/TrEMBL),   A0A8C0T0L3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409544   ⟸   XM_038553616
- UniProtKB: A0A8C0NNP5 (UniProtKB/TrEMBL),   A0A8C0T0L3 (UniProtKB/TrEMBL),   A0A8I3RY99 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845020705   ⟸   ENSCAFT00845026264
RefSeq Acc Id: ENSCAFP00845020698   ⟸   ENSCAFT00845026255


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000764 Ensembl
  ENSCAFG00000057870 UniProtKB/TrEMBL
  ENSCAFG00030017311 UniProtKB/TrEMBL
  ENSCAFG00040017435 UniProtKB/TrEMBL
  ENSCAFG00845014684 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000096336.1 UniProtKB/TrEMBL
  ENSCAFT00030031900.1 UniProtKB/TrEMBL
  ENSCAFT00040032221.1 UniProtKB/TrEMBL
  ENSCAFT00845026255 ENTREZGENE
  ENSCAFT00845026255.1 UniProtKB/TrEMBL
  ENSCAFT00845026264.1 UniProtKB/TrEMBL
InterPro CD225/Dispanin_fam UniProtKB/TrEMBL
KEGG Report cfa:607660 UniProtKB/TrEMBL
NCBI Gene PRRT1 ENTREZGENE
PANTHER NG5 UniProtKB/TrEMBL
  PROLINE-RICH TRANSMEMBRANE PROTEIN 1 UniProtKB/TrEMBL
Pfam CD225 UniProtKB/TrEMBL
UniProt A0A8C0NNP5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T0L3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NKE5_CANLF UniProtKB/TrEMBL
  A0A8I3RY99 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49684 ENTREZGENE