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Gene: Nt5c1a (5'-nucleotidase, cytosolic IA) Rattus norvegicus

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Symbol:

Nt5c1a

Name:

5'-nucleotidase, cytosolic IA

RGD ID:

1310908

Description:

Enables 5'-nucleotidase activity. Involved in adenosine metabolic process. Predicted to be active in cytosol. Orthologous to human NT5C1A (5'-nucleotidase, cytosolic IA); PARTICIPATES IN monoterpenoid biosynthetic pathway; niacin metabolic pathway; purine metabolic pathway; INTERACTS WITH alpha-Zearalanol; bisphenol A; nitrofen.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cytosolic 5'-nucleotidase 1A; LOC313574

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NT5C1A (5'-nucleotidase, cytosolic IA)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Nt5c1a (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nt5c1a (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NT5C1A (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NT5C1A (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nt5c1a (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NT5C1A (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NT5C1A (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nt5c1a (5'-nucleotidase, cytosolic IA)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NT5C1A (5'-nucleotidase, cytosolic IA)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nt5c1a (5'-nucleotidase, cytosolic IA)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nt5c1aa (5'-nucleotidase, cytosolic IAa)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	nt5c1ab (5'-nucleotidase, cytosolic IAb)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nt5c1b	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	140,758,219 - 140,782,706 (+)	NCBI		GRCr8
mRatBN7.2	5	135,473,107 - 135,494,400 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	135,473,231 - 135,499,338 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	138,179,527 - 138,194,604 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	139,949,490 - 139,964,567 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	139,956,631 - 139,971,708 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	140,888,862 - 140,909,322 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	140,888,973 - 140,904,207 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	144,678,889 - 144,697,399 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	142,509,257 - 142,524,280 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	142,514,549 - 142,529,506 (+)	NCBI
Celera	5	134,012,146 - 134,027,198 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nt5c1a	Rat	Charcot-Marie-Tooth disease dominant intermediate C		ISO	NT5C1A (Homo sapiens)	8554872	ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate C	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nt5c1a	Rat	2,4-D	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	[lard co-treated with Cholesterol more ...	CTD	PMID:37567420
Nt5c1a	Rat	4-hydroxyphenyl retinamide	increases expression	ISO	Nt5c1a (Mus musculus)	6480464	Fenretinide results in increased expression of NT5C1A mRNA	CTD	PMID:28973697
Nt5c1a	Rat	5-fluorouracil	decreases response to substance	ISO	Nt5c1a (Mus musculus)	6480464	NT5C1A protein results in decreased susceptibility to Fluorouracil	CTD	PMID:16362297
Nt5c1a	Rat	5-fluorouracil	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	NT5C1A protein results in decreased susceptibility to [Fluorouracil co-treated with Cladribine]	CTD	PMID:16362297
Nt5c1a	Rat	aflatoxin B1	decreases methylation	ISO	NT5C1A (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of NT5C1A intron	CTD	PMID:30157460
Nt5c1a	Rat	aldehydo-D-glucose	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	[lard co-treated with Cholesterol more ...	CTD	PMID:37567420
Nt5c1a	Rat	alpha-Zearalanol	decreases expression	EXP		6480464	Zeranol results in decreased expression of NT5C1A mRNA	CTD	PMID:35163327
Nt5c1a	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of NT5C1A mRNA	CTD	PMID:35163327
Nt5c1a	Rat	benzene	increases expression	ISO	Nt5c1a (Mus musculus)	6480464	Benzene results in increased expression of NT5C1A mRNA	CTD	PMID:37084897
Nt5c1a	Rat	benzo[a]pyrene	affects methylation	ISO	NT5C1A (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of NT5C1A promoter	CTD	PMID:27901495
Nt5c1a	Rat	benzo[a]pyrene	increases methylation	ISO	NT5C1A (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of NT5C1A exon	CTD	PMID:27901495
Nt5c1a	Rat	benzo[e]pyrene	decreases methylation	ISO	NT5C1A (Homo sapiens)	6480464	benzo(e)pyrene results in decreased methylation of NT5C1A intron	CTD	PMID:30157460
Nt5c1a	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of NT5C1A mRNA	CTD	PMID:30816183 and PMID:32528016
Nt5c1a	Rat	CGP 52608	multiple interactions	ISO	NT5C1A (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to NT5C1A gene]	CTD	PMID:28238834
Nt5c1a	Rat	cladribine	decreases response to substance	ISO	Nt5c1a (Mus musculus)	6480464	NT5C1A protein results in decreased susceptibility to Cladribine	CTD	PMID:16362297
Nt5c1a	Rat	cladribine	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	NT5C1A protein results in decreased susceptibility to [Fluorouracil co-treated with Cladribine]	CTD	PMID:16362297
Nt5c1a	Rat	copper(II) sulfate	increases expression	ISO	NT5C1A (Homo sapiens)	6480464	Copper Sulfate results in increased expression of NT5C1A mRNA	CTD	PMID:19549813
Nt5c1a	Rat	D-glucose	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	[lard co-treated with Cholesterol more ...	CTD	PMID:37567420
Nt5c1a	Rat	fructose	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	[lard co-treated with Cholesterol more ...	CTD	PMID:37567420
Nt5c1a	Rat	glucose	multiple interactions	ISO	Nt5c1a (Mus musculus)	6480464	[lard co-treated with Cholesterol more ...	CTD	PMID:37567420
Nt5c1a	Rat	lipopolysaccharide	decreases expression	ISO	NT5C1A (Homo sapiens)	6480464	Lipopolysaccharides results in decreased expression of NT5C1A mRNA	CTD	PMID:35811015
Nt5c1a	Rat	lipopolysaccharide	multiple interactions	ISO	NT5C1A (Homo sapiens)	6480464	[S-(1 more ...	CTD	PMID:35811015
Nt5c1a	Rat	methapyrilene	decreases methylation	ISO	NT5C1A (Homo sapiens)	6480464	Methapyrilene results in decreased methylation of NT5C1A intron	CTD	PMID:30157460
Nt5c1a	Rat	nitrofen	decreases expression	EXP		6480464	nitrofen results in decreased expression of NT5C1A mRNA	CTD	PMID:33484710
Nt5c1a	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of NT5C1A mRNA	CTD	PMID:30723492
Nt5c1a	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of NT5C1A mRNA	CTD	PMID:35163327
Nt5c1a	Rat	resveratrol	multiple interactions	ISO	NT5C1A (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of NT5C1A mRNA	CTD	PMID:23557933
Nt5c1a	Rat	S-(1,2-dichlorovinyl)-L-cysteine	decreases expression	ISO	NT5C1A (Homo sapiens)	6480464	S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of NT5C1A mRNA	CTD	PMID:35811015
Nt5c1a	Rat	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	NT5C1A (Homo sapiens)	6480464	[S-(1 more ...	CTD	PMID:35811015
Nt5c1a	Rat	titanium dioxide	decreases methylation	ISO	Nt5c1a (Mus musculus)	6480464	titanium dioxide results in decreased methylation of NT5C1A promoter	CTD	PMID:35295148
Nt5c1a	Rat	trichloroethene	increases methylation	EXP		6480464	Trichloroethylene results in increased methylation of NT5C1A gene	CTD	PMID:27618143
Nt5c1a	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of NT5C1A mRNA	CTD	PMID:33387578

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nt5c1a	Rat	adenosine metabolic process		IDA		2291861		RGD
Nt5c1a	Rat	adenosine metabolic process	involved_in	IBA	PANTHER:PTN001264375 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nt5c1a	Rat	allantoin metabolic process	involved_in	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	allantoin metabolic process	involved_in	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	AMP catabolic process	involved_in	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	AMP catabolic process	involved_in	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	dAMP catabolic process	involved_in	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	dAMP catabolic process	involved_in	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	dGMP catabolic process	involved_in	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	dGMP catabolic process	involved_in	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	IMP catabolic process	involved_in	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	IMP catabolic process	involved_in	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	nucleotide metabolic process	involved_in	IEA	InterPro:IPR010394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nt5c1a	Rat	purine nucleoside monophosphate catabolic process	acts_upstream_of_or_within	ISO	Nt5c1a (Mus musculus)	1624291	PMID:21873433	RGD	PMID:21873433

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nt5c1a	Rat	cytoplasm	located_in	IEA	InterPro:IPR010394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nt5c1a	Rat	cytosol	is_active_in	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	cytosol	is_active_in	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	cytosol	is_active_in	IBA	MGI:1918131 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nt5c1a	Rat	5'-nucleotidase activity		IDA		2291861		RGD
Nt5c1a	Rat	5'-nucleotidase activity	enables	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	5'-nucleotidase activity	enables	IBA	MGI:1918131 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Nt5c1a	Rat	5'-nucleotidase activity	enables	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996 more ...	RGD	PMID:11133996 more ...
Nt5c1a	Rat	5'-nucleotidase activity	enables	IEA	InterPro:IPR010394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nt5c1a	Rat	magnesium ion binding	enables	ISO	NT5C1A (Homo sapiens)	1624291	PMID:8967393	RGD	PMID:8967393
Nt5c1a	Rat	magnesium ion binding	enables	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	magnesium ion binding	enables	IEA	InterPro:IPR010394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nt5c1a	Rat	nucleotide binding	enables	IEA	InterPro:IPR010394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Nt5c1a	Rat	obsolete IMP 5'-nucleotidase activity	enables	ISO	NT5C1A (Homo sapiens)	1624291	PMID:11133996	RGD	PMID:11133996
Nt5c1a	Rat	obsolete IMP 5'-nucleotidase activity	enables	IEA	UniProtKB:Q9BXI3 and ensembl:ENSP00000235628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Nt5c1a	Rat	protein binding	enables	ISO	NT5C1A (Homo sapiens)	1624291	UniProtKB:Q16543 more ...	RGD	PMID:25416956 more ...

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Nt5c1a	Rat	monoterpenoid biosynthetic pathway		IEA		6907045		KEGG	rno:00760
Nt5c1a	Rat	niacin metabolic pathway		IEA		6907045		KEGG	rno:00760
Nt5c1a	Rat	purine metabolic pathway		IEA		6907045		KEGG	rno:00230
Nt5c1a	Rat	pyrimidine metabolic pathway		IEA		6907045		KEGG	rno:00240

BioCyc Pathways

adenosine nucleotides degradation II

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Enzymes of adenosine metabolism in the brain: diurnal rhythm and the effect of sleep deprivation.	Mackiewicz M, etal., J Neurochem. 2003 Apr;85(2):348-57.
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:11133996	PMID:17686601	PMID:21873433

Nt5c1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	140,758,219 - 140,782,706 (+)	NCBI		GRCr8
mRatBN7.2	5	135,473,107 - 135,494,400 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	135,473,231 - 135,499,338 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	138,179,527 - 138,194,604 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	139,949,490 - 139,964,567 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	139,956,631 - 139,971,708 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	140,888,862 - 140,909,322 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	140,888,973 - 140,904,207 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	144,678,889 - 144,697,399 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	142,509,257 - 142,524,280 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	142,514,549 - 142,529,506 (+)	NCBI
Celera	5	134,012,146 - 134,027,198 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

NT5C1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	39,651,229 - 39,672,107 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	39,651,229 - 39,672,107 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	40,116,901 - 40,137,779 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	39,897,380 - 39,910,297 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	39,793,885 - 39,806,803	NCBI
Celera	1	38,406,541 - 38,419,451 (-)	NCBI		Celera
Cytogenetic Map	1	p34.2	NCBI
HuRef	1	38,243,165 - 38,256,339 (-)	NCBI		HuRef
CHM1_1	1	40,240,158 - 40,253,074 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	39,519,647 - 39,541,479 (-)	NCBI		T2T-CHM13v2.0

Nt5c1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	123,095,026 - 123,119,128 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	123,095,297 - 123,110,068 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	123,201,230 - 123,225,339 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	123,201,504 - 123,216,275 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	122,878,796 - 122,893,450 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	122,703,861 - 122,718,510 (+)	NCBI		MGSCv36	mm8
Celera	4	121,533,931 - 121,548,583 (+)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	57.4	NCBI

Nt5c1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	17,172,217 - 17,188,756 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	17,172,217 - 17,188,597 (-)	NCBI	ChiLan1.0	ChiLan1.0

NT5C1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	187,143,395 - 187,170,949 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	186,281,086 - 186,308,577 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	38,943,479 - 38,962,804 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	40,268,821 - 40,289,221 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	40,275,870 - 40,289,221 (-)	Ensembl	panpan1.1		panPan2

NT5C1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	3,209,771 - 3,230,104 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	3,209,869 - 3,222,983 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	3,468,550 - 3,488,826 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	3,329,926 - 3,350,213 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	3,329,942 - 3,350,172 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	3,206,121 - 3,226,364 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	3,267,136 - 3,287,417 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	3,282,706 - 3,302,991 (+)	NCBI		UU_Cfam_GSD_1.0

Nt5c1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	55,703,426 - 55,717,483 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	21,535,467 - 21,542,588 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	21,535,197 - 21,542,417 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NT5C1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	95,473,266 - 95,497,000 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	95,473,259 - 95,497,645 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	88,561,471 - 88,585,252 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NT5C1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	93,261,913 - 93,278,063 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	93,264,543 - 93,277,688 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	23,598,905 - 23,620,239 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nt5c1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	22,151,246 - 22,168,322 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	22,147,077 - 22,168,337 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Nt5c1a
80 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	42
Count of miRNA genes:	40
Interacting mature miRNAs:	41
Transcripts:	ENSRNOT00000020524
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
1300122	Wbc1	White blood cell count QTL 1	2.75		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	5	125392826	139989768	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	129132428	143070159	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	120740824	143608494	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
7411722	Strs6	Sensitivity to stroke QTL 6	3.9		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	5	134972980	138113556	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	95	64	61	32	25	32	6	191	97	75	45	54	29


RefSeq Transcripts	NM_001107976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020524 ⟹ ENSRNOP00000020524

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	140,888,973 - 140,904,207 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113648 ⟹ ENSRNOP00000083268

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	135,473,245 - 135,493,922 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113843 ⟹ ENSRNOP00000087156

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	135,473,231 - 135,499,338 (+)	Ensembl

RefSeq Acc Id:

NM_001107976 ⟹ NP_001101446

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	140,758,343 - 140,773,366 (+)	NCBI
mRatBN7.2	5	135,473,231 - 135,488,254 (+)	NCBI
Rnor_6.0	5	140,888,986 - 140,904,009 (+)	NCBI
Rnor_5.0	5	144,678,889 - 144,697,399 (+)	NCBI
RGSC_v3.4	5	142,509,257 - 142,524,280 (+)	RGD
Celera	5	134,012,146 - 134,027,198 (+)	RGD

Sequence:

show sequence

GTTCCTTGAGCTCCCTGTCTCCGACGCTGTCTTCTCCCGCCCGGCCGGATCGGATCCGAGCCGGAACATGGAACCAAGGCAGCCCCCGGAGGCCCGAGAACCCGGACCAGGGGCAGAGACCGCCGCGG
TGCCGCGCTGGGAGGAAGCCAAGACGTTCTATGACAATCTCTCGCCCAAGAAGAAACCCAAATCGCCAAAGCCTCAGAATGCGGTCACCATCGCAGTGTCCTCCAGAGCCTTGTTCCGAATGGATGAG
GAACAGAGGATCTACACGGAGCAGGGTGTAGAGGAGTACGTACGATACCAGCTGGAGCACGAGAACGAGCCCTTCAGCCCTGGGCCCGCCTTCCCCTTTGTAAAGGCCCTGGAGGCTGTGAACAAGCA
ACTTCGAGAGCTGTACCCCGATAGCGAAGATATCTTTGACATCGTCCTCATGACCAACAACCATGCTCAGGTGGGGGTTCGTCTCATCAACAGTATCAACCATTACGACCTGTTCATTGAGCGATTCT
GCATGACAGGTGGGAATAGCCCCATCTGCTACCTCAAGGCCTACCATACCAACCTCTACTTGTCAGCCGATGCAGAAAAAGTGCGAGAAGCCATTGATGAGGGGATTGCAGCTGCCACCATCTTCAGC
CCTAGCAAGGATGTGGTCGTGTCCCAGAGTCAGCTCCGCGTGGCCTTCGATGGGGACGCAGTACTTTTCTCCGATGAGTCAGAGCGCATTGTCAAGGCCCATGGGCTGGACAGATTCTTTGAGCATGA
GAAGGCCCACGAGAACAAACCTTTGGCGCAGGGTCCCCTAAAGGGCTTCCTGGAAGCACTAGGTAGGCTGCAGAAGAAATTCTACTCCAAAGGCCTGCGGCTGGAGTGCCCGATTCGTACTTACTTGG
TGACAGCGCGCAGCGCAGCCAGTTCTGGAGCCCGGGCCCTCAAGACCCTACGTAGCTGGGGCCTGGAGACGGATGAGGCCTTATTCCTAGCTGGAGCACCCAAGGGCCCTCTTCTTGAGAAGATCCGC
CCACACATCTTCTTTGATGACCAGATGTTTCACGTGGCCGGAGCTCAGGAGATGGGCACCGTGGCCGCCCACGTGCCTTACGGCGTAGCTCAGAATCCACGGAGGGAAAAGCAGTCCCTAGGCGCACA
GTAG

hide sequence

RefSeq Acc Id:

XM_017593399 ⟹ XP_017448888

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	140,758,219 - 140,782,706 (+)	NCBI
mRatBN7.2	5	135,473,107 - 135,494,400 (+)	NCBI
Rnor_6.0	5	140,888,862 - 140,909,322 (+)	NCBI

Sequence:

show sequence

TCAGAGTTCCCCTAAATGTCAAGCGGGCGGCTTGGACGGGCGGGCGGGGCGGGCTCACTCGCAC
TCCCTCCCGGCCCTGCCGCCTGCCTCTCCCACCCAGGACGCGCCTCCCTCCCTCGGCTCAGTTCCTTGAGCTCCCTGTCTCCGACGCTGTCTTCTCCCGCCCGGCCGGATCGGATCCGAGCCGGAACA
TGGAACCAAGGCAGCCCCCGGAGGCCCGAGAACCCGGACCAGGGGCAGAGACCGCCGCGGTGCCGCGCTGGGAGGAAGCCAAGACGTTCTATGACAATCTCTCGCCCAAGAAGAAACCCAAATCGGCC
TTGGCTCATCCTGGTGACAGAGATCGTAAGTTGTGGCCTGCCTGTCTCAGGAGTTTGGAGTGTGCCCACGGAGGCTCCAGAGATGGTGGATTCTCAGCCAAAGCCTCAGAATGCGGTCACCATCGCAG
TGTCCTCCAGAGCCTTGTTCCGAATGGATGAGGAACAGAGGATCTACACGGAGCAGGGTGTAGAGGAGTACGTACGATACCAGCTGGAGCACGAGAACGAGCCCTTCAGCCCTGGGCCCGCCTTCCCC
TTTGTAAAGGCCCTGGAGGCTGTGAACAAGCAACTTCGAGAGCTGTACCCCGATAGCGAAGATATCTTTGACATCGTCCTCATGACCAACAACCATGCTCAGGTGGGGGTTCGTCTCATCAACAGTAT
CAACCATTACGACCTGTTCATTGAGCGATTCTGCATGACAGGTGGGAATAGCCCCATCTGCTACCTCAAGGCCTACCATACCAACCTCTACTTGTCAGCCGATGCAGAAAAAGTGCGAGAAGCCATTG
ATGAGGGGATTGCAGCTGCCACCATCTTCAGCCCTAGCAAGGATGTGGTCGTGTCCCAGAGTCAGCTCCGCGTGGCCTTCGATGGGGACGCAGTACTTTTCTCCGATGAGTCAGAGCGCATTGTCAAG
GCCCATGGGCTGGACAGATTCTTTGAGCATGAGAAGGCCCACGAGAACAAACCTTTGGCGCAGGGTCCCCTAAAGGGCTTCCTGGAAGCACTAGGTAGGCTGCAGAAGAAATTCTACTCCAAAGGCCT
GCGGCTGGAGTGCCCGATTCGTACTTACTTGGTGACAGCGCGCAGCGCAGCCAGTTCTGGAGCCCGGGCCCTCAAGACCCTACGTAGCTGGGGCCTGGAGACGGATGAGGCCTTATTCCTAGCTGGAG
CACCCAAGGGCCCTCTTCTTGAGAAGATCCGCCCACACATCTTCTTTGATGACCAGATGTTTCACGTGGCCGGAGCTCAGGAGATGGGCACCGTGGCCGCCCACGTGCCTTACGGCGTAGCTCAGAAT
CCACGGAGGGAAAAGCAGTCCCTAGGCGCACAGTAGCTGAGCTACCTTGCTCCAGGCCCTGTCACGTTTCTGAACCGCGGCTGGTGAGCTTTTCAGGCTCCTCACTGTCCACCCTCCTGCATGCCGCA
CTCATCTCTCTGTACCAGGTACTCTTAGAACGTTAGGAAGACAGAGCCAGCAGTCTCGAAATCCCTCCTGGGCAAACATTGCCATGACCCTGGCTAGAAAGCAGCACTCGGCAGAGTATCCTGGGTGT
CAGAGAGAAACTGGTGGGACAGAGAGTTGTGTAGACAGAGAAGCCAGCATGCCTAAGGGCTTGGGATGAGAACTATCTCTAACGTAGCGCAAAGAACACTGTGTGAACGTGGGTAGATTTAACATCTA
AAGCAGATCTGGCATGGATGCATGACTTAAGTTCCCCTTTTTCATAAGCCTTGGCATACTACCATTTTTTTGGGTGGCTTTCAATTTGTTCTTTAGCCAAAGAAGCTTGGTTTTATAAGATTGTGCAC
TAAATTAATCATTTAGTGCTGGGGCTGCTAGTACCCACGGCACCTGTGTGGATTACAAAAGGACACTGTCTAAGTGAATGCATTACAAAACTAATGGCCCTTCCTTCCTCTGGCCCGAGCCGGGATAT
AGGCTAGATTCCAGCCCTTTGCCCCTCAACCCCGAGGCCCATCAAATGAGAAGTGTGCACAGTGCTGCACAGTGCTGCACAGATTCTCTCTCGATAATTTTTTCATGTTTAGAAACCACTGCCCAAGG
TGACCCTTTGCTTGCTGTGATTTGCTAACCTGAGCCGTGGAGAGCTGCTACATGCAAGGTGTTTGAAGAACTGAAGGGAGGAACGTCGCCCACATGCAGATTCTCCTCTAGCCAGCAGAGGGCACTGC
AGGCTCTCTCTGAAGAAGGCTTCAGTGGCTCGCCAACTCTGGGTTTCCTTTGCCTCTAGCTTCAGGGCAAAGTTCAGTTAGTCCTGCCTGCCGGTCTCCTCAGCTCAGTCCTGGGTCTGCCAGTCATT
TCCACCTTCCGTGCTGTAAGGAAGTTCTCCTAACAGAGAAGGAACTCTAGCCCTAAATATGGAGAAACCACAGGCTCTAAAGCGAGTCGTTGTCCAGGCTGTGCCTGAGGTGTAGGTGCCACAGTGAG
ATGTGGGAAGTATCAGGTCTGTTCTGAAACCAAAGACGCTAAGAAAGTGGTAGCTTAGGGAGGAATGAGTTGAATGCGTCCCAGCATGGTTCTGCTGTGGAGAGTGAGTAGAAGTCAGTCAGAGCTAC
CCCGGAAGTAATACGCTGTCATCAGGGTGCTATGCAAAGGATTCTGGGATGAACCAGCCTTCCTGAGAGATATCCGCGGTTGATCCATCTTTGCATGAATCTCTACAGCCCTTTCTTCTCCACCTGAT
GAGTGATGGACCACCTCCTTCTTTGCTAAGCAGCCCTGGCACTCAGAGGAAGGGTGGAAGAGTGGATGGTTGCCCCCCTTGGAAGACAAGAAAGGGCAAGCATGAATGTGTACAATGATTGCCTGGTT
CCCACAGGGATTTCAGCAATGAGGGAACCCAGAAGCATCATCAGAGGGCCAGGAGCTGAGGAGGGCCAGAGGAGAGGAGCCTGGAGGTAGGGGGAAGGCATCCGGGGACTCAAACCTCTGTCCTTCTA
GGATTTGAATCAGGGTCTGAATGAGTTCGTGTTCTGGGCAGTGTGTCCTGGAGTGACAGCTGCAGGAAGGAGGAGAAGGAAGATGCAAGAACTCCCAGAAGTGAGTACCAGCTTGCTCTACGGGCATG
CAGATGCTATTCCTGGAAGGGACGTGAGGTTGACACCCACCACAGCTGCTTAACGGAGCCATTGGCATTATTGCAGCCAGAAGGGTGTGGGGTGAAGGTGTCTTCACACAGGGTCGTTTTCGTCATTA
TAACCAGGACATCAAAGTCTGCAAGGGGATCTCCTTGCACTATCTGTACCCCACTTCTGGCCAGAGATGCCATGTGGCCCAAGAACAGCTGCAAGAAGAGGAAACTGGGGTGACAGAGGAAGTTTCAA
GGCCCTTTCCATCTTCACTGGATCGCACTAGAGCCCCTTGAAGGGTCTCAGCAGAGGCTCATGGTCAGTGGTCACAAGAATCTTGTAAGGATATGCAGAGCAGAGACTCACAGATTGTCCTTAGGTTG
CCCAGTCAGGAAAGACCTGTGGACTGTGAAGACAGCACCAGCTGCTGCTGAATTTGGGATGAGATCTAGTGCCCAGGGCCTGCTCATTGAAGGCTGCAGACCCTCCCAGGTTTCCCAGGAAACAGGAA
CAGTGCTGTGCCAGAAGTAAAAAGATAAGGTGCAGTAAAGGGCTGTGGCTCTCACTGGAACCACCATTAATAGATACAGACAGCACTTGACAGCGCAGAACGGTCCAAATTCTATTATTGAGACCACA
GATGAGCATCTCAAGCCTGGGCAGAAGCTTTTGAAGCTGGTACAACAGGCCAGAAGTCCTGGGGGCAGGCTCGAGCTGCAGCCAGACAGTCCTCCTGATGGCCTCAAGAGCTGAGAAGCCTGGCAGTG
TGAAGCTTTATTTATTGTGTTACCAGGAGATTTAAAAACCGACTGAGCACCAAAGCCCCAGGCAAAGCCTTTAACTGCAACACTGGCGTAGAGGAGCCACAGATCACCGGAGCTCTTTAGCTGGAAGT
ACCATGTCCCTATGTCTGGCAGAACTCTGCTCCTAGGAAGTGCTTGCCAACAGGATTCCAGACCCAGTGGAACTGCCACTCAGCAGAACAGTAGCTCTGTTTGTTATTAAGCATGGAGACGGCTAAGA
TTATTACAGAACTCCCTTCAGGGGAGGGTGATATAGTTGGGCATCTGGCTCAGTCGGAAGAGTGCTTGCCTACTGAATTCAAAAGCCTGGATTCACAACACACAACAATGCATAAGCTAGACATGGTG
GTGCACACCTACGATCCCAACACCAGAGAGACAGAGACAGGGGGAATCGGAAGGTCAGGGTGACCCTTGGCTGCATAGCCAGTCCACAGCCAGTCTAGGGTCCATGAGACCCCATCACAAAAAGGAGA
AAGCAAACCTTTACTTACGTGGTGGTCCAACTGCATTCATGGGAATGCAGCAGAATATGCTAGAAAGAAAATAGAAGCTAGCAAGGTGTTCAGATCCAAAATAGACTTGATGGTACACCTGTATTCAA
TTAGTGTGTATCCATGCGGTCAAAGACATGATCAGAATATCAAATGTGGTAAACAGCTCTGCCCCAAGTCCCTGGGGTATCCCTTGATACCATCAGCTGCCCACACTCCTCCACTGGAAATGCATCTT
GCCGTAATCCAGCCTTCATGAGATGTTCCAGTACTGTGGCCCATGACTACTCCCTAGCGGTATCCTGACCAGGGATCCTGATCGGGAACCACCATAATTTGCTCAAAGTTACCCAGCTAGCAGATGTC
AGTGATGGGACAACAAAGCCACCCTCACAATGGAATGTTCCAGAATCCACTACAAACATGACAAGCTGTCCTATCTACTGTCATGCTTGAAGTCACCATCCCATCATGACAGTCCCCCTTACAAAGCC
CAGGCTTGGCCTCAGATTCTTCAGGCAGCATTTCAGGAGGACAAGGAGAAGGAGGAGGAGGAAGATGAGGATGAAGAGGACGAGGAGGATGAGGACAAGGACAAGGAGGACCATTGGCCCCGTGGCTG
GCAACTTTTCAGGAAAGGATACCTGAGAACAAGTGTCCTGGGTTCTACCCTTAAGGCAAAGTGCAGAAACCTTGCTTGCCAGTAGGTGACACTGTAGGCTGGCACTCAGCTGTGCCAGTAGTGCATGG
CTTGATTTTCTCTCCTATGCTACTGGTTACTATGCTGGACTCCAGCAGCCTAAAAGGACTTCCTTTAGGTGCTCTGACAATGTTCCTGAAACATCTCCATATGACGAGCTGATGGCTCTCACCGAAAA
CCACTGTGACCTGTGTATGGGGAAACATTCATGAATGTGTGCCTCTGTACGGACTGAGTACGTATTTATGGGTGCCGCAGCTCGGATTTCTCTGCTGGTGACTCTGTGTGCACAAGTGTGTCTGTGTC
TCTGCGTGTCATGCACACTTGCGAGCTTGGAGTGTGTACAGACAGTTATATTAGTTGAGGATCCTGGGCCCCACATGCTGATGACCAGCGTTACTCCTGGGGACTCTCCTCATCCCATGGGCACTGCA
TGGGATCACCTGAGGGCCCTGAAGCCAGGCCTCTCAGTCTTCCTCTCTAGCTTTCTGGTTCTGTTCCACTTCTGTTGCCTCTGACTTCTCTGTCTCCTTCCCCTGTGGCTCTGCAGCTTTGGGGAGGA
AGTGGCAGAATCTGCCTCCACCTGACTCAATCCCCACGCATCTCTTCCCTCCCCGCAACAGTGCCAGGGTTAATACGGTCCAATTAGGAGCTATCTCACGGCCACCACTAGGAAAGCTGACATCTTAC
TGGGCCTCCTGCTCTTGTCAGACATGCAAGACCTTTGACCTTGACTTGGAAGTGTCTCCCTGATGCCCTCCACGTCACCCCCACCCCAGAGAACGAACAAATTGTGTTTGCAAAGTTAGAGTTTCTCT
AAGGCGAACCAAAAATCTGCAGACTGGCATTTCATACTCCTAGCTCAGGCTGAATGTGCCTTCATGGCTGTCGGCCACTACTCAAGGCTAGGCTTGTAGCTGACACTGATCAGAAAGCTGCCAAGGTC
ATTGCAAACATACTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGGGGCCACAAACCCTGTGTCTACAGGAGCCACACAAGAAACAGGCGCAGAGGGCATTGGGCAAG
GTCTTGAGAAGAAAAATAACATCGAGAATCCAGAAACCAGTATACCCATGTAGGAATTTGGGCTGGTGGGCCCTGGTATTCTATCTTTTTGTTTTGTTTTCTGAGAAATTAGAAATCTGAACTTTCAA
TTATTGGCAACCATTTCAAGTTTAGAAAACTTTGTATAGCCCAAAAGAAGCTTTTGTTGTTAGTCAGATCCACCTCTCCAATCTCCAGTTTGCTTTCTGCCTGAAGCCCAATGAATTGGGACTTTTAG
ACTCAAATTACTGAGAATGGAAGAGACATTACTCTCAAAATCACAGCTTGTGGTCTTTAGGAGACCTCAGAGATGACATAAAATATCCCTGGTGTATTTTAAGTGCTTGGGTACGAGCCAGGCTTGGC
AGTGCACACCTGTTATCCCGGCACTAAAGAAACTGGGATTGGACCATGCTAAATTCAAAGCCAGCCTGGCCTACATATGAAGACTCTATTTAAAAAAAAAA

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Protein RefSeqs	NP_001101446	(Get FASTA)	NCBI Sequence Viewer
	XP_017448888	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL80372	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000083268
	ENSRNOP00000083268.1
	ENSRNOP00000087156.1

RefSeq Acc Id:

NP_001101446 ⟸ NM_001107976

- UniProtKB:

D3ZVD3 (UniProtKB/TrEMBL), A6IS21 (UniProtKB/TrEMBL), A0A8I5ZYY7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEPRQPPEAREPGPGAETAAVPRWEEAKTFYDNLSPKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHA
QVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGR
LQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ

hide sequence

RefSeq Acc Id:	XP_017448888 ⟸ XM_017593399
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZYY7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSGRLGRAGGAGSLALPPGPAACLSHPGRASLPRLSSLSSLSPTLSSPARPDRIRAGTWNQGSPRRPENPDQGQRPPRCRAGRKPRRSMTISRPRRNPNRPWLILVTEIVSCGLPVSGVWSVPTEAP EMVDSQPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYH TNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKT LRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ hide sequence

Ensembl Acc Id:

ENSRNOP00000020524 ⟸ ENSRNOT00000020524

Ensembl Acc Id:

ENSRNOP00000083268 ⟸ ENSRNOT00000113648

Ensembl Acc Id:

ENSRNOP00000087156 ⟸ ENSRNOT00000113843

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZVD3-F1-model_v2	AlphaFold	D3ZVD3	1-362	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13694003

Promoter ID:

EPDNEW_R4528

Type:

single initiation site

Name:

Nt5c1a_1

Description:

5'-nucleotidase, cytosolic IA

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	140,888,985 - 140,889,045	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-40015	BioCyc
BioCyc Pathway	SALVADEHYPOX-PWY [adenosine nucleotides degradation II]	BioCyc
BioCyc Pathway Image	SALVADEHYPOX-PWY	BioCyc
Ensembl Genes	ENSRNOG00000015283	Ensembl
	ENSRNOG00000068555	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000113648	ENTREZGENE
	ENSRNOT00000113648.1	UniProtKB/TrEMBL
	ENSRNOT00000113843.1	UniProtKB/TrEMBL
InterPro	5-nucleotidase	UniProtKB/TrEMBL
KEGG Report	rno:313574	UniProtKB/TrEMBL
NCBI Gene	313574	ENTREZGENE
PANTHER	CYTOSOLIC 5'-NUCLEOTIDASE 1A	UniProtKB/TrEMBL
	PTHR31367	UniProtKB/TrEMBL
Pfam	5-nucleotidase	UniProtKB/TrEMBL
PhenoGen	Nt5c1a	PhenoGen
RatGTEx	ENSRNOG00000015283	RatGTEx
	ENSRNOG00000068555	RatGTEx
UniProt	A0A8I5ZYY7	ENTREZGENE, UniProtKB/TrEMBL
	A6IS21	ENTREZGENE, UniProtKB/TrEMBL
	D3ZVD3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Nt5c1a	5'-nucleotidase, cytosolic IA	Nt5c1a_predicted	5'-nucleotidase, cytosolic IA (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Nt5c1a_predicted	5'-nucleotidase, cytosolic IA (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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