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Gene: Pkhd1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin) Rattus norvegicus

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Symbol:

Pkhd1

Name:

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

RGD ID:

1308476

Description:

Predicted to be involved in several processes, including establishment of centrosome localization; regulation of epithelial cell proliferation; and regulation of intracellular signal transduction. Predicted to act upstream of with a positive effect on branching morphogenesis of an epithelial tube and cell-cell junction organization. Predicted to act upstream of or within cilium assembly and kidney development. Predicted to be located in several cellular components, including apical plasma membrane; extracellular exosome; and microtubule cytoskeleton. Used to study autosomal recessive polycystic kidney disease. Biomarker of autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease and polycystic kidney disease 4. Orthologous to human PKHD1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin); INTERACTS WITH bisphenol A; cefaloridine; rotenone.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

AABR07067023.1; fibrocystin; LOC301287; PKHD1, fibrocystin/polyductin; polycystic kidney and hepatic disease 1; polycystic kidney and hepatic disease 1 (autosomal recessive); polycystic kidney and hepatic disease 1 homolog; polycystic kidney and hepatic disease 1 homolog (human)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

Pkhd1^pck

Genetic Models:

PCK-P2rx7^em8Mcwi

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	30,040,466 - 30,533,834 (-)	NCBI		GRCr8
mRatBN7.2	9	22,547,396 - 23,037,443 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	22,549,513 - 23,037,381 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	26,164,969 - 26,736,704 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	26,636,334 - 26,707,571 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	25,025,958 - 25,065,045 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	9	25,159,062 - 25,593,163 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	18,833,903 - 19,338,716 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	18,831,224 - 19,254,940 (-)	NCBI
Celera	9	20,127,204 - 20,618,569 (-)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	autosomal recessive polycystic kidney disease		IAGP		70439		RGD
Pkhd1	Rat	autosomal recessive polycystic kidney disease		ISO	RGD:1318267	14700917	DNA:deletion:exon:	RGD
Pkhd1	Rat	autosomal recessive polycystic kidney disease	severity	ISO	RGD:1318266	11062506	DNA:missense mutations:cds:	RGD
Pkhd1	Rat	autosomal recessive polycystic kidney disease		IEP		1642441	protein:decreased expression:kidney	RGD
Pkhd1	Rat	autosomal recessive polycystic kidney disease	susceptibility	ISO	RGD:1318266	70439	DNA:missense mutations, nonsense mutations: :multiple	RGD
Pkhd1	Rat	autosomal recessive polycystic kidney disease	susceptibility	IAGP		70439	DNA:splice site mutation:intron:IVS35-2A>T	RGD
Pkhd1	Rat	cholangitis		ISO	RGD:1318267	14700923		RGD
Pkhd1	Rat	choledochal cyst		ISO	RGD:1318267	14700991	DNA:deletion:exon:	RGD
Pkhd1	Rat	Congenital Hepatic Fibrosis		ISO	RGD:1318266	14700992	DNA:mutations:cds:c.7994T>C, p.(Leu2665Pro),c.8518C>T, p.(Arg2840Cys)(human)	RGD
Pkhd1	Rat	Congenital Hepatic Fibrosis		ISO	RGD:1318267	14700919		RGD
Pkhd1	Rat	liver cirrhosis		ISO	RGD:1318267	14700917	DNA:deletion:exon:	RGD
Pkhd1	Rat	Medullary Sponge Kidney		ISO	RGD:1318267	14700919		RGD
Pkhd1	Rat	Pancreatic Cyst		ISO	RGD:1318267	14700921		RGD
Pkhd1	Rat	Pancreatic Cyst		ISO	RGD:1318267	14700917	DNA:deletion:exon:	RGD
Pkhd1	Rat	polycystic kidney disease		ISO	RGD:1318267	1642440	mRNA:decreased expression:kidney	RGD
Pkhd1	Rat	polycystic liver disease		ISO	RGD:1318267	14700921		RGD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	autosomal dominant polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Autosomal dominant polycystic kidney disease \| ClinVar Annotator: match by more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:12925574\|PMID:14741187\|PMID:14971004\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16199547\|PMID:16523049\|PMID:16876319\|PMID:17576681\|PMID:18414213\|PMID:18503009\|PMID:19021639\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20301501\|PMID:20413436\|PMID:20460933\|PMID:21228398\|PMID:21274727\|PMID:21407107\|PMID:21493627\|PMID:21945273\|PMID:22034641\|PMID:22415584\|PMID:23389334\|PMID:23582048\|PMID:24033266\|PMID:24121792\|PMID:24162162\|PMID:24710345\|PMID:24984783\|PMID:25034658\|PMID:25114813\|PMID:25124979\|PMID:25153916\|PMID:25193386\|PMID:25326637\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:25771912\|PMID:26385851\|PMID:26489027\|PMID:26489029\|PMID:26673778\|PMID:26695994\|PMID:26721323\|PMID:27151922\|PMID:27225849\|PMID:27491411\|PMID:27752906\|PMID:27894351\|PMID:28170084\|PMID:28252636\|PMID:28364132\|PMID:28375157\|PMID:28492532\|PMID:28578020\|PMID:28851938\|PMID:28862642\|PMID:29068549\|PMID:29095814\|PMID:29643536\|PMID:29801666\|PMID:29956005\|PMID:30260789\|PMID:30275481\|PMID:30507656\|PMID:30586318\|PMID:30595564\|PMID:30650191\|PMID:30773290\|PMID:30787879\|PMID:31010483\|PMID:31130284\|PMID:31308072\|PMID:31328266\|PMID:31395617\|PMID:31589614\|PMID:31730820\|PMID:31738409\|PMID:31844813\|PMID:31980526\|PMID:32203225\|PMID:32359821\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:32939031\|PMID:33059616\|PMID:33059727\|PMID:33112055\|PMID:33123899\|PMID:33226606\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33569422\|PMID:33716212\|PMID:33742171\|PMID:33774617\|PMID:33845788\|PMID:33940108\|PMID:34008892\|PMID:34405919\|PMID:34426522\|PMID:34487536\|PMID:34536170\|PMID:35372954\|PMID:35373060\|PMID:35497799\|PMID:35715958\|PMID:35812281\|PMID:36307859\|PMID:36703223\|PMID:36938085\|PMID:38057357\|PMID:38374194\|PMID:39071699\|PMID:9536098
Pkhd1	Rat	autosomal recessive polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Autosomal recessive polycystic kidney disease	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:12925574\|PMID:14741187\|PMID:14971004\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16199547\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:17576681\|PMID:18414213\|PMID:18503009\|PMID:19021639\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:20460933\|PMID:20575693\|PMID:21228398\|PMID:21274727\|PMID:21493627\|PMID:21790888\|PMID:21945273\|PMID:22034641\|PMID:22415584\|PMID:22882926\|PMID:22995991\|PMID:23041322\|PMID:23265383\|PMID:23389334\|PMID:23582048\|PMID:23757202\|PMID:24009235\|PMID:24033266\|PMID:24121792\|PMID:24162162\|PMID:24710345\|PMID:24984783\|PMID:25114813\|PMID:25124979\|PMID:25153916\|PMID:25193386\|PMID:25525159\|PMID:25589618\|PMID:25640679\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:25741880\|PMID:25741895\|PMID:25741913\|PMID:25771912\|PMID:25966130\|PMID:26139440\|PMID:26385851\|PMID:26489027\|PMID:26489029\|PMID:26633542\|PMID:26673778\|PMID:26695994\|PMID:26721323\|PMID:27151922\|PMID:27225849\|PMID:27491411\|PMID:27577217\|PMID:27595491\|PMID:27752906\|PMID:27894351\|PMID:28170084\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28578020\|PMID:28851938\|PMID:28862642\|PMID:28933340\|PMID:29095814\|PMID:29520754\|PMID:29643536\|PMID:29801666\|PMID:29956005\|PMID:30260789\|PMID:30275481\|PMID:30343465\|PMID:30366773\|PMID:30507656\|PMID:30566001\|PMID:30595564\|PMID:30650191\|PMID:30655312\|PMID:30773290\|PMID:30787879\|PMID:31130284\|PMID:31395954\|PMID:31730820\|PMID:31738409\|PMID:31813136\|PMID:31844813\|PMID:31938409\|PMID:31980526\|PMID:32203225\|PMID:32256442\|PMID:32359821\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32576985\|PMID:32799815\|PMID:32939031\|PMID:33059616\|PMID:33112055\|PMID:33123899\|PMID:33226606\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33569422\|PMID:33716212\|PMID:33845788\|PMID:33940108\|PMID:34008892\|PMID:34426522\|PMID:9536098
Pkhd1	Rat	autosomal recessive polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Autosomal recessive polycystic kidney disease \| ClinVar Annotator: match by more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:12925574\|PMID:14741187\|PMID:14971004\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16199547\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:16897190\|PMID:17576681\|PMID:18414213\|PMID:18503009\|PMID:18769842\|PMID:19021639\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20301501\|PMID:20413436\|PMID:20460933\|PMID:20575693\|PMID:21228398\|PMID:21274727\|PMID:21407107\|PMID:21493627\|PMID:21790888\|PMID:21945273\|PMID:22034641\|PMID:22415584\|PMID:22882926\|PMID:22995991\|PMID:23041322\|PMID:23265383\|PMID:23389334\|PMID:23582048\|PMID:23757202\|PMID:24009235\|PMID:24033266\|PMID:24121792\|PMID:24162162\|PMID:24710345\|PMID:24984783\|PMID:25034658\|PMID:25114813\|PMID:25124979\|PMID:25153916\|PMID:25193386\|PMID:25326637\|PMID:25525159\|PMID:25589618\|PMID:25640679\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:25741880\|PMID:25771912\|PMID:25966130\|PMID:26139440\|PMID:26385851\|PMID:26489027\|PMID:26489029\|PMID:26633542\|PMID:26673778\|PMID:26695994\|PMID:26721323\|PMID:27151922\|PMID:27225849\|PMID:27491411\|PMID:27577217\|PMID:27595491\|PMID:27752906\|PMID:27894351\|PMID:28166811\|PMID:28170084\|PMID:28252636\|PMID:28364132\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28578020\|PMID:28851938\|PMID:28862642\|PMID:28933340\|PMID:29068549\|PMID:29095814\|PMID:29520754\|PMID:29643536\|PMID:29801666\|PMID:29947050\|PMID:29956005\|PMID:30017326\|PMID:30260789\|PMID:30275481\|PMID:30343465\|PMID:30366773\|PMID:30507656\|PMID:30566001\|PMID:30586318\|PMID:30595564\|PMID:30650191\|PMID:30655312\|PMID:30773290\|PMID:30787879\|PMID:31010483\|PMID:31130284\|PMID:31308072\|PMID:31328266\|PMID:31395617\|PMID:31395954\|PMID:31589614\|PMID:31624253\|PMID:31730820\|PMID:31738409\|PMID:31813136\|PMID:31844813\|PMID:31938409\|PMID:31980526\|PMID:32203225\|PMID:32256442\|PMID:32304219\|PMID:32359821\|PMID:32384486\|PMID:3239877\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32576985\|PMID:32799815\|PMID:32901917\|PMID:32939031\|PMID:33059616\|PMID:33059727\|PMID:33112055\|PMID:33123899\|PMID:33226606\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33569422\|PMID:33716212\|PMID:33742171\|PMID:33774617\|PMID:33845788\|PMID:33940108\|PMID:33964006\|PMID:34008892\|PMID:34032358\|PMID:34096032\|PMID:34405919\|PMID:34426522\|PMID:34487536\|PMID:34536170\|PMID:34573383\|PMID:34977057\|PMID:35314707\|PMID:35368817\|PMID:35372954\|PMID:35373060\|PMID:35497799\|PMID:35627109\|PMID:35715958\|PMID:35778421\|PMID:35783601\|PMID:35812281\|PMID:36065636\|PMID:36307859\|PMID:36691356\|PMID:36703223\|PMID:36938085\|PMID:37372416\|PMID:37535131\|PMID:38057357\|PMID:38125876\|PMID:38374194\|PMID:39071699\|PMID:9536098
Pkhd1	Rat	Caroli disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Caroli disease	ClinVar	PMID:1189128\|PMID:11898128\|PMID:12846734\|PMID:12874454\|PMID:15108277\|PMID:15108281\|PMID:15698423\|PMID:15805161\|PMID:16133180\|PMID:19914852\|PMID:20413436\|PMID:21228398\|PMID:25701400\|PMID:25741868\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27894351\|PMID:28492530\|PMID:28492532\|PMID:29068549\|PMID:30343465\|PMID:30773290\|PMID:31130284\|PMID:31844813\|PMID:31980526\|PMID:32359821\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:35715958
Pkhd1	Rat	colon cancer		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Malignant tumor of colon	ClinVar	PMID:12846734\|PMID:14741187\|PMID:15805161\|PMID:21493627\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:28492532\|PMID:33532864\|PMID:33716212
Pkhd1	Rat	cystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Familial cystic renal disease \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:11898128\|PMID:19940839\|PMID:25741868\|PMID:27225849\|PMID:28492532
Pkhd1	Rat	familial Mediterranean fever		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Periodic disease	ClinVar	PMID:15805161\|PMID:16876319\|PMID:21228398\|PMID:25326637\|PMID:26673778\|PMID:27225849\|PMID:28492532\|PMID:28862642
Pkhd1	Rat	genetic disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:19914852\|PMID:20413436\|PMID:21274727\|PMID:23041322\|PMID:23265383\|PMID:25124979\|PMID:25701400\|PMID:25741868\|PMID:26695994\|PMID:27225849\|PMID:28375157\|PMID:28492532\|PMID:29956005\|PMID:30773290\|PMID:31395617\|PMID:31395954\|PMID:32304219\|PMID:32574212\|PMID:32799815\|PMID:33532864\|PMID:33774617
Pkhd1	Rat	genetic disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:11919560\|PMID:15698423\|PMID:15805161\|PMID:19914852\|PMID:20413436\|PMID:23041322\|PMID:25741868\|PMID:26695994\|PMID:28492532\|PMID:29956005\|PMID:31395954
Pkhd1	Rat	Habitual Abortions		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Pregnancy loss, recurrent, susceptibility to, 3	ClinVar
Pkhd1	Rat	homocystinuria		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: CBS deficiency	ClinVar	PMID:25741868
Pkhd1	Rat	Isolated Caroli Disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Cystic dilatation of the intrahepatic biliary tree	ClinVar	PMID:1189128\|PMID:11898128\|PMID:12874454\|PMID:15698423\|PMID:15805161\|PMID:16133180\|PMID:19914852\|PMID:20413436\|PMID:25701400\|PMID:25741868\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27894351\|PMID:28492532\|PMID:29068549\|PMID:31130284\|PMID:31844813\|PMID:31980526\|PMID:32359821\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:35715958
Pkhd1	Rat	oligohydramnios		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Oligohydramnios \| ClinVar Annotator: match by term: anhydramnios	ClinVar	PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:19914852\|PMID:20413436\|PMID:21274727\|PMID:25124979\|PMID:25741868\|PMID:26695994\|PMID:27225849\|PMID:28375157\|PMID:28492532\|PMID:30773290\|PMID:32574212\|PMID:32799815\|PMID:33532864\|PMID:35005812
Pkhd1	Rat	polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Polycystic kidney disease \| ClinVar Annotator: match by term: Polycystic more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:21228398\|PMID:21274727\|PMID:21790888\|PMID:22882926\|PMID:23041322\|PMID:23582048\|PMID:23757202\|PMID:24033266\|PMID:24162162\|PMID:25124979\|PMID:25326637\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28862642\|PMID:29068549\|PMID:29801666\|PMID:29956005\|PMID:30343465\|PMID:30773290\|PMID:31130284\|PMID:31328266\|PMID:31395954\|PMID:31813136\|PMID:31844813\|PMID:31980526\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:33112055\|PMID:33123899\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33940108\|PMID:34008892\|PMID:34032358
Pkhd1	Rat	polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Polycystic kidney disease \| ClinVar Annotator: match by term: Polycystic more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:21228398\|PMID:21274727\|PMID:21790888\|PMID:22882926\|PMID:23041322\|PMID:23582048\|PMID:23757202\|PMID:24033266\|PMID:24162162\|PMID:25124979\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28862642\|PMID:29068549\|PMID:29801666\|PMID:29956005\|PMID:30343465\|PMID:30773290\|PMID:31130284\|PMID:31395954\|PMID:31813136\|PMID:31844813\|PMID:31980526\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:33112055\|PMID:33123899\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33940108\|PMID:34008892
Pkhd1	Rat	polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Polycystic kidney disease	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:21228398\|PMID:21274727\|PMID:21790888\|PMID:22882926\|PMID:23041322\|PMID:23582048\|PMID:23757202\|PMID:24033266\|PMID:24162162\|PMID:25124979\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28862642\|PMID:29801666\|PMID:29956005\|PMID:30343465\|PMID:30773290\|PMID:31130284\|PMID:31395954\|PMID:31813136\|PMID:31844813\|PMID:31980526\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:33112055\|PMID:33123899\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33940108\|PMID:34008892
Pkhd1	Rat	polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Polycystic kidney disease \| ClinVar Annotator: match by term: Polycystic more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:21228398\|PMID:21274727\|PMID:21790888\|PMID:22882926\|PMID:23041322\|PMID:23582048\|PMID:23757202\|PMID:24033266\|PMID:24162162\|PMID:25124979\|PMID:25326637\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:25741905\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28862642\|PMID:29068549\|PMID:29801666\|PMID:29956005\|PMID:30343465\|PMID:30773290\|PMID:31130284\|PMID:31328266\|PMID:31395954\|PMID:31813136\|PMID:31844813\|PMID:31980526\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:33112055\|PMID:33123899\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33940108\|PMID:34008892\|PMID:34032358
Pkhd1	Rat	polycystic kidney disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Polycystic kidney disease \| ClinVar Annotator: match by term: Polycystic more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:21228398\|PMID:21274727\|PMID:21790888\|PMID:22882926\|PMID:23041322\|PMID:23582048\|PMID:23757202\|PMID:24033266\|PMID:24162162\|PMID:25124979\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492530\|PMID:28492532\|PMID:28862642\|PMID:29801666\|PMID:29956005\|PMID:30343465\|PMID:30773290\|PMID:31130284\|PMID:31813136\|PMID:31844813\|PMID:31980526\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:33112055\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33940108\|PMID:34008892
Pkhd1	Rat	polycystic kidney disease 3		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: PKD3 \| ClinVar Annotator: match by term: Polycystic kidney disease more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:12925574\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16199547\|PMID:16523049\|PMID:16632497\|PMID:17576681\|PMID:18503009\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20413436\|PMID:20460933\|PMID:21228398\|PMID:21274727\|PMID:22415584\|PMID:22882926\|PMID:23041322\|PMID:23582048\|PMID:24033266\|PMID:24162162\|PMID:24984783\|PMID:25034658\|PMID:25124979\|PMID:25153916\|PMID:25193386\|PMID:25701400\|PMID:25741868\|PMID:26489027\|PMID:26489029\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28170084\|PMID:28252636\|PMID:28375157\|PMID:28492532\|PMID:28578020\|PMID:29095814\|PMID:29801666\|PMID:29956005\|PMID:30275481\|PMID:30343465\|PMID:30507656\|PMID:30586318\|PMID:30650191\|PMID:30773290\|PMID:30787879\|PMID:31130284\|PMID:31395954\|PMID:31589614\|PMID:31738409\|PMID:31813136\|PMID:31844813\|PMID:31980526\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:32939031\|PMID:33059616\|PMID:33112055\|PMID:33123899\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33845788\|PMID:33940108\|PMID:34008892\|PMID:9536098
Pkhd1	Rat	polycystic kidney disease 3		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: GANAB-related condition \| ClinVar Annotator: match by term: PKD3	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:12925574\|PMID:14741187\|PMID:14971004\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16199547\|PMID:16523049\|PMID:17576681\|PMID:18414213\|PMID:18503009\|PMID:19021639\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20301501\|PMID:20413436\|PMID:20460933\|PMID:21228398\|PMID:21274727\|PMID:21407107\|PMID:21493627\|PMID:21945273\|PMID:22034641\|PMID:22415584\|PMID:23389334\|PMID:23582048\|PMID:24033266\|PMID:24162162\|PMID:24710345\|PMID:24984783\|PMID:25034658\|PMID:25114813\|PMID:25124979\|PMID:25153916\|PMID:25193386\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:25771912\|PMID:26385851\|PMID:26489027\|PMID:26489029\|PMID:26673778\|PMID:26695994\|PMID:26721323\|PMID:27151922\|PMID:27225849\|PMID:27491411\|PMID:27752906\|PMID:27894351\|PMID:28170084\|PMID:28252636\|PMID:28364132\|PMID:28375157\|PMID:28492532\|PMID:28578020\|PMID:28851938\|PMID:29068549\|PMID:29095814\|PMID:29643536\|PMID:29801666\|PMID:29956005\|PMID:30260789\|PMID:30275481\|PMID:30507656\|PMID:30586318\|PMID:30595564\|PMID:30650191\|PMID:30773290\|PMID:30787879\|PMID:31010483\|PMID:31130284\|PMID:31308072\|PMID:31328266\|PMID:31395617\|PMID:31589614\|PMID:31730820\|PMID:31738409\|PMID:31844813\|PMID:31980526\|PMID:32203225\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:32939031\|PMID:33059616\|PMID:33059727\|PMID:33112055\|PMID:33123899\|PMID:33226606\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33569422\|PMID:33716212\|PMID:33742171\|PMID:33774617\|PMID:33845788\|PMID:33940108\|PMID:34008892\|PMID:34405919\|PMID:34426522\|PMID:34487536\|PMID:34536170\|PMID:35372954\|PMID:35373060\|PMID:35497799\|PMID:35812281\|PMID:36307859\|PMID:36703223\|PMID:36938085\|PMID:38057357\|PMID:38374194\|PMID:39071699\|PMID:9536098
Pkhd1	Rat	polycystic kidney disease 4		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: PKHD1-related condition \| ClinVar Annotator: match by term: POLYCYSTIC KIDNEY more ...	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:12925574\|PMID:14741187\|PMID:14971004\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16199547\|PMID:16523049\|PMID:16632497\|PMID:16876319\|PMID:17576681\|PMID:18414213\|PMID:18503009\|PMID:18769842\|PMID:19021639\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:19940939\|PMID:20301501\|PMID:20413436\|PMID:20460933\|PMID:21228398\|PMID:21274727\|PMID:21407107\|PMID:21493627\|PMID:21945273\|PMID:22034641\|PMID:22415584\|PMID:22882926\|PMID:23041322\|PMID:23389334\|PMID:23582048\|PMID:24009235\|PMID:24033266\|PMID:24121792\|PMID:24162162\|PMID:24710345\|PMID:24984783\|PMID:25034658\|PMID:25114813\|PMID:25124979\|PMID:25153916\|PMID:25193386\|PMID:25326637\|PMID:25525159\|PMID:25589618\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:25741880\|PMID:25771912\|PMID:25966130\|PMID:26139440\|PMID:26385851\|PMID:26489027\|PMID:26489029\|PMID:26633542\|PMID:26673778\|PMID:26695994\|PMID:26721323\|PMID:26862157\|PMID:27151922\|PMID:27225849\|PMID:27491411\|PMID:27577217\|PMID:27595491\|PMID:27752906\|PMID:27894351\|PMID:28135719\|PMID:28166811\|PMID:28170084\|PMID:28252636\|PMID:28364132\|PMID:28375157\|PMID:28492532\|PMID:28578020\|PMID:28851938\|PMID:28862642\|PMID:28933340\|PMID:29068549\|PMID:29095814\|PMID:29520754\|PMID:29643536\|PMID:29801666\|PMID:29947050\|PMID:29956005\|PMID:30076350\|PMID:30260789\|PMID:30275481\|PMID:30343465\|PMID:30366773\|PMID:30507656\|PMID:30566001\|PMID:30586318\|PMID:30595564\|PMID:30650191\|PMID:30655312\|PMID:30773290\|PMID:30787879\|PMID:31010483\|PMID:31130284\|PMID:31308072\|PMID:31328266\|PMID:31395617\|PMID:31395954\|PMID:31589614\|PMID:31624253\|PMID:31730820\|PMID:31738409\|PMID:31785789\|PMID:31813136\|PMID:31844813\|PMID:31938409\|PMID:31980526\|PMID:32203225\|PMID:32256442\|PMID:32304219\|PMID:32359821\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32576985\|PMID:32799815\|PMID:32901917\|PMID:32924121\|PMID:32939031\|PMID:33057194\|PMID:33059616\|PMID:33059727\|PMID:33112055\|PMID:33123899\|PMID:33226606\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33569422\|PMID:33716212\|PMID:33742171\|PMID:33774617\|PMID:33845788\|PMID:33940108\|PMID:34008892\|PMID:34032358\|PMID:34405919\|PMID:34426522\|PMID:34487536\|PMID:34536170\|PMID:34573383\|PMID:35314707\|PMID:35368817\|PMID:35372954\|PMID:35373060\|PMID:35497799\|PMID:35627109\|PMID:35715958\|PMID:35778421\|PMID:35783601\|PMID:35812281\|PMID:35982159\|PMID:36065636\|PMID:36307859\|PMID:36549658\|PMID:36691356\|PMID:36703223\|PMID:36938085\|PMID:37535131\|PMID:38057357\|PMID:38125876\|PMID:38374194\|PMID:39071699\|PMID:9536098
Pkhd1	Rat	polycystic liver disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Congenital cystic disease of liver	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16876319\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:20413436\|PMID:20460933\|PMID:21228398\|PMID:21274727\|PMID:22415584\|PMID:24162162\|PMID:24984783\|PMID:25124979\|PMID:25193386\|PMID:25326637\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:26489027\|PMID:26489029\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492532\|PMID:28578020\|PMID:28862642\|PMID:29068549\|PMID:29801666\|PMID:30275481\|PMID:30507656\|PMID:30650191\|PMID:30773290\|PMID:31130284\|PMID:31395617\|PMID:31589614\|PMID:31738409\|PMID:31844813\|PMID:31980526\|PMID:32359821\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:32939031\|PMID:33112055\|PMID:33123899\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33774617\|PMID:33845788\|PMID:33940108\|PMID:35715958
Pkhd1	Rat	polycystic liver disease 1		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Isolated autosomal dominant polycystic liver disease	ClinVar	PMID:1189128\|PMID:11898128\|PMID:11919560\|PMID:12506140\|PMID:12846734\|PMID:12874454\|PMID:14741187\|PMID:15108277\|PMID:15108281\|PMID:15696446\|PMID:15698423\|PMID:15706593\|PMID:15805161\|PMID:16133180\|PMID:16199545\|PMID:16523049\|PMID:16876319\|PMID:19176689\|PMID:19914852\|PMID:19940839\|PMID:20413436\|PMID:20460933\|PMID:21228398\|PMID:21274727\|PMID:22415584\|PMID:24162162\|PMID:24984783\|PMID:25124979\|PMID:25193386\|PMID:25326637\|PMID:25525159\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:26489027\|PMID:26489029\|PMID:26673778\|PMID:26695994\|PMID:27151922\|PMID:27225849\|PMID:27752906\|PMID:27894351\|PMID:28375157\|PMID:28492532\|PMID:28578020\|PMID:28862642\|PMID:29068549\|PMID:29801666\|PMID:30275481\|PMID:30507656\|PMID:30650191\|PMID:30773290\|PMID:31130284\|PMID:31395617\|PMID:31589614\|PMID:31738409\|PMID:31844813\|PMID:31980526\|PMID:32359821\|PMID:32384486\|PMID:32398770\|PMID:32571524\|PMID:32574212\|PMID:32799815\|PMID:32939031\|PMID:33112055\|PMID:33123899\|PMID:33282801\|PMID:33426401\|PMID:33437033\|PMID:33532864\|PMID:33774617\|PMID:33845788\|PMID:33940108\|PMID:35715958
Pkhd1	Rat	prostate cancer		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Malignant tumor of prostate	ClinVar	PMID:23265383\|PMID:28492532
Pkhd1	Rat	Wilson disease		ISO	RGD:1318266	8554872	ClinVar Annotator: match by term: Wilson disease	ClinVar	PMID:12846734\|PMID:14741187\|PMID:15805161\|PMID:21493627\|PMID:25326637\|PMID:25646624\|PMID:25701400\|PMID:25741868\|PMID:28492532\|PMID:33532864\|PMID:33716212

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	autosomal recessive polycystic kidney disease		ISO	RGD:1318266	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:16133180\|PMID:18988797\|PMID:19524688\|PMID:21685914
Pkhd1	Rat	choledochal cyst		ISO	RGD:1318266	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18988797

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	autosomal recessive polycystic kidney disease		ISS	RGD:1318267	13592920	OMIM:263200	MouseDO
Pkhd1	Rat	Caroli syndrome		ISS	RGD:1318267	13592920		MouseDO
Pkhd1	Rat	polycystic kidney disease 4		ISS	RGD:1318267	13592920	OMIM:263200	MouseDO

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	polycystic kidney disease 4		ISO	RGD:1318266	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	17beta-estradiol	increases expression	ISO	RGD:1318267	6480464	Estradiol results in increased expression of PKHD1 mRNA	CTD	PMID:39298647
Pkhd1	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1318267	6480464	Tetrachlorodibenzodioxin affects the expression of PKHD1 mRNA	CTD	PMID:21570461
Pkhd1	Rat	2,4-dibromophenyl 2,4,5-tribromophenyl ether	affects expression	ISO	RGD:1318267	6480464	2,2',4,4',5-brominated diphenyl ether affects the expression of PKHD1 mRNA	CTD	PMID:38648751
Pkhd1	Rat	4,4'-sulfonyldiphenol	multiple interactions	ISO	RGD:1318266	6480464	[bisphenol S co-treated with Fulvestrant] results in increased methylation of PKHD1 gene	CTD	PMID:31601247
Pkhd1	Rat	4-hydroxyphenyl retinamide	increases expression	ISO	RGD:1318267	6480464	Fenretinide results in increased expression of PKHD1 mRNA	CTD	PMID:28973697
Pkhd1	Rat	aflatoxin B1	decreases expression	ISO	RGD:1318267	6480464	Aflatoxin B1 results in decreased expression of PKHD1 mRNA	CTD	PMID:19770486
Pkhd1	Rat	aflatoxin B1	decreases expression	ISO	RGD:1318266	6480464	Aflatoxin B1 results in decreased expression of PKHD1 mRNA	CTD	PMID:32234424
Pkhd1	Rat	benzo[a]pyrene	increases mutagenesis	ISO	RGD:1318266	6480464	Benzo(a)pyrene results in increased mutagenesis of PKHD1 gene	CTD	PMID:25435355
Pkhd1	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1318266	6480464	Benzo(a)pyrene results in decreased expression of PKHD1 mRNA	CTD	PMID:32234424
Pkhd1	Rat	benzo[a]pyrene	decreases methylation	ISO	RGD:1318266	6480464	Benzo(a)pyrene results in decreased methylation of PKHD1 5' UTR	CTD	PMID:27901495
Pkhd1	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1318266	6480464	Benzo(a)pyrene results in increased methylation of PKHD1 promoter	CTD	PMID:27901495
Pkhd1	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1318267	6480464	Benzo(a)pyrene results in decreased expression of PKHD1 mRNA	CTD	PMID:19770486\|PMID:21715664
Pkhd1	Rat	bisphenol A	increases expression	ISO	RGD:1318267	6480464	bisphenol A results in increased expression of PKHD1 mRNA	CTD	PMID:21932408
Pkhd1	Rat	bisphenol A	increases methylation	ISO	RGD:1318266	6480464	bisphenol A results in increased methylation of PKHD1 gene	CTD	PMID:31601247
Pkhd1	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of PKHD1 mRNA	CTD	PMID:32145629
Pkhd1	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of PKHD1 mRNA	CTD	PMID:25181051
Pkhd1	Rat	cadmium atom	multiple interactions	ISO	RGD:1318266	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PKHD1 more ...	CTD	PMID:35301059
Pkhd1	Rat	cadmium dichloride	multiple interactions	ISO	RGD:1318266	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PKHD1 more ...	CTD	PMID:35301059
Pkhd1	Rat	carbon nanotube	decreases expression	ISO	RGD:1318267	6480464	Nanotubes, Carbon analog results in decreased expression of PKHD1 mRNA	CTD	PMID:25620056
Pkhd1	Rat	cefaloridine	decreases expression	EXP		6480464	Cephaloridine results in decreased expression of PKHD1 mRNA	CTD	PMID:18500788
Pkhd1	Rat	CGP 52608	multiple interactions	ISO	RGD:1318266	6480464	CGP 52608 promotes the reaction [RORA protein binds to PKHD1 gene]	CTD	PMID:28238834
Pkhd1	Rat	choline	multiple interactions	ISO	RGD:1318267	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ...	CTD	PMID:20938992
Pkhd1	Rat	cyclosporin A	increases expression	ISO	RGD:1318266	6480464	Cyclosporine results in increased expression of PKHD1 mRNA	CTD	PMID:27989131
Pkhd1	Rat	folic acid	multiple interactions	ISO	RGD:1318267	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ...	CTD	PMID:20938992
Pkhd1	Rat	fulvestrant	multiple interactions	ISO	RGD:1318266	6480464	[bisphenol S co-treated with Fulvestrant] results in increased methylation of PKHD1 gene	CTD	PMID:31601247
Pkhd1	Rat	hydroquinone O-beta-D-glucopyranoside	decreases expression	ISO	RGD:1318266	6480464	Arbutin results in decreased expression of PKHD1 mRNA	CTD	PMID:17103032
Pkhd1	Rat	L-methionine	multiple interactions	ISO	RGD:1318267	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ...	CTD	PMID:20938992
Pkhd1	Rat	methotrexate	decreases expression	ISO	RGD:1318266	6480464	Methotrexate results in decreased expression of PKHD1 mRNA	CTD	PMID:24449571
Pkhd1	Rat	mono(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1318267	6480464	mono-(2-ethylhexyl)phthalate results in increased expression of PKHD1 mRNA	CTD	PMID:22401849
Pkhd1	Rat	N-Nitrosopyrrolidine	decreases expression	ISO	RGD:1318266	6480464	N-Nitrosopyrrolidine results in decreased expression of PKHD1 mRNA	CTD	PMID:32234424
Pkhd1	Rat	O-methyleugenol	decreases expression	ISO	RGD:1318266	6480464	methyleugenol results in decreased expression of PKHD1 mRNA	CTD	PMID:32234424
Pkhd1	Rat	okadaic acid	decreases expression	ISO	RGD:1318266	6480464	Okadaic Acid results in decreased expression of PKHD1 mRNA	CTD	PMID:38832940
Pkhd1	Rat	ozone	multiple interactions	ISO	RGD:1318267	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ...	CTD	PMID:34911549
Pkhd1	Rat	phenobarbital	multiple interactions	ISO	RGD:1318267	6480464	NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of PKHD1 mRNA]	CTD	PMID:19482888
Pkhd1	Rat	phenobarbital	decreases expression	ISO	RGD:1318267	6480464	Phenobarbital results in decreased expression of PKHD1 mRNA	CTD	PMID:19270015\|PMID:19482888
Pkhd1	Rat	pirinixic acid	multiple interactions	ISO	RGD:1318266	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ...	CTD	PMID:19710929
Pkhd1	Rat	potassium dichromate	decreases expression	ISO	RGD:1318267	6480464	Potassium Dichromate results in decreased expression of PKHD1 mRNA	CTD	PMID:23608068
Pkhd1	Rat	rotenone	decreases expression	EXP		6480464	Rotenone results in decreased expression of PKHD1 mRNA	CTD	PMID:28374803
Pkhd1	Rat	sodium arsenite	affects methylation	ISO	RGD:1318266	6480464	sodium arsenite affects the methylation of PKHD1 gene	CTD	PMID:28589171
Pkhd1	Rat	sodium arsenite	decreases expression	ISO	RGD:1318266	6480464	sodium arsenite results in decreased expression of PKHD1 mRNA	CTD	PMID:34032870
Pkhd1	Rat	sodium arsenite	decreases methylation	ISO	RGD:1318267	6480464	sodium arsenite results in decreased methylation of PKHD1 gene	CTD	PMID:32068019
Pkhd1	Rat	tamoxifen	affects expression	ISO	RGD:1318267	6480464	Tamoxifen affects the expression of PKHD1 mRNA	CTD	PMID:20937368
Pkhd1	Rat	tetrachloromethane	increases expression	ISO	RGD:1318267	6480464	Carbon Tetrachloride results in increased expression of PKHD1 mRNA	CTD	PMID:27339419
Pkhd1	Rat	tetrachloromethane	affects expression	ISO	RGD:1318267	6480464	Carbon Tetrachloride affects the expression of PKHD1 mRNA	CTD	PMID:31919559
Pkhd1	Rat	theophylline	decreases expression	ISO	RGD:1318266	6480464	Theophylline results in decreased expression of PKHD1 mRNA	CTD	PMID:18951874
Pkhd1	Rat	triptonide	increases expression	ISO	RGD:1318267	6480464	triptonide results in increased expression of PKHD1 mRNA	CTD	PMID:33045310
Pkhd1	Rat	valproic acid	affects expression	ISO	RGD:1318266	6480464	Valproic Acid affects the expression of PKHD1 mRNA	CTD	PMID:25979313
Pkhd1	Rat	zoledronic acid	decreases expression	ISO	RGD:1318266	6480464	zoledronic acid results in decreased expression of PKHD1 mRNA	CTD	PMID:24714768

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	biological_process		ND		1598407	09/2007: no relevant rat data	RGD
Pkhd1	Rat	branching morphogenesis of an epithelial tube	acts_upstream_of_positive_effect	ISO	RGD:1318267	1624291	PMID:20875407	RGD	PMID:20875407
Pkhd1	Rat	branching morphogenesis of an epithelial tube	acts_upstream_of_positive_effect	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cell-cell junction organization	acts_upstream_of_positive_effect	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cell-cell junction organization	acts_upstream_of_positive_effect	ISO	RGD:1318267	1624291	PMID:20875407	RGD	PMID:20875407
Pkhd1	Rat	cilium assembly	acts_upstream_of_or_within	ISO	RGD:1318267	1624291	MGI:3826780 PMID:18235088	RGD	PMID:18235088
Pkhd1	Rat	cilium assembly	acts_upstream_of_or_within	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	epithelial cell morphogenesis	involved_in	ISO	RGD:12309722	1624291	PMID:32698519	RGD	PMID:32698519
Pkhd1	Rat	establishment of centrosome localization	involved_in	ISO	RGD:12309722	1624291	PMID:32698519	RGD	PMID:32698519
Pkhd1	Rat	establishment of mitotic spindle orientation	involved_in	ISO	RGD:1318267	1624291	PMID:19959710	RGD	PMID:19959710
Pkhd1	Rat	establishment of mitotic spindle orientation	involved_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	intracellular calcium ion homeostasis	involved_in	ISO	RGD:1318266	1624291	PMID:17669261	RGD	PMID:17669261
Pkhd1	Rat	intracellular calcium ion homeostasis	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	kidney development	acts_upstream_of_or_within	ISO	RGD:1318267	1624291	PMID:15067314	RGD	PMID:15067314
Pkhd1	Rat	kidney development	acts_upstream_of_or_within	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	negative regulation of apoptotic process	involved_in	ISO	RGD:1318266	1624291	PMID:19943112, PMID:21300060	RGD	PMID:19943112\|PMID:21300060
Pkhd1	Rat	negative regulation of apoptotic process	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	negative regulation of epithelial cell apoptotic process	involved_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	negative regulation of epithelial cell apoptotic process	involved_in	ISO	RGD:1318267	1624291	PMID:20875407	RGD	PMID:20875407
Pkhd1	Rat	negative regulation of NF-kappaB transcription factor activity	involved_in	ISO	RGD:1318266	1624291	PMID:21300060	RGD	PMID:21300060
Pkhd1	Rat	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	involved_in	ISO	RGD:1318266	1624291	PMID:21300060	RGD	PMID:21300060
Pkhd1	Rat	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	positive regulation of cell population proliferation	involved_in	ISO	RGD:1318266	1624291	PMID:19943112	RGD	PMID:19943112
Pkhd1	Rat	positive regulation of cell population proliferation	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	positive regulation of epithelial cell proliferation	involved_in	ISO	RGD:1318267	1624291	PMID:20875407	RGD	PMID:20875407
Pkhd1	Rat	positive regulation of epithelial cell proliferation	involved_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	regulation of cell adhesion	involved_in	ISO	RGD:12309722	1624291	PMID:32698519	RGD	PMID:32698519
Pkhd1	Rat	regulation of cell-cell adhesion	involved_in	ISO	RGD:12309722	1624291	PMID:31398719	RGD	PMID:31398719
Pkhd1	Rat	regulation of cell-matrix adhesion	involved_in	ISO	RGD:12309722	1624291	PMID:31398719	RGD	PMID:31398719
Pkhd1	Rat	regulation of centrosome duplication	involved_in	ISO	RGD:1318266	1624291	PMID:20554582	RGD	PMID:20554582
Pkhd1	Rat	regulation of centrosome duplication	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	regulation of cholangiocyte proliferation	involved_in	ISO	RGD:1318266	1624291	PMID:30898581	RGD	PMID:30898581
Pkhd1	Rat	regulation of cholangiocyte proliferation	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	regulation of ERK1 and ERK2 cascade	involved_in	ISO	RGD:1318266	1624291	PMID:17669261	RGD	PMID:17669261
Pkhd1	Rat	regulation of ERK1 and ERK2 cascade	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	regulation of establishment of planar polarity	involved_in	ISO	RGD:1318267	1624291	PMID:19959710	RGD	PMID:19959710
Pkhd1	Rat	regulation of establishment of planar polarity	involved_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	regulation of TOR signaling	involved_in	ISO	RGD:1318266	1624291	PMID:19524688	RGD	PMID:19524688
Pkhd1	Rat	regulation of TOR signaling	involved_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	9+0 non-motile cilium	located_in	ISO	RGD:1318267	1624291	PMID:24586199	RGD	PMID:24586199
Pkhd1	Rat	9+0 non-motile cilium	located_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	apical plasma membrane	located_in	ISO	RGD:1318266	1624291	PMID:16243292	RGD	PMID:16243292
Pkhd1	Rat	apical plasma membrane	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	apical plasma membrane	located_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	apical plasma membrane	located_in	ISO	RGD:1318267	1624291	PMID:18202188	RGD	PMID:18202188
Pkhd1	Rat	cell projection	located_in	IEA	UniProtKB-KW:KW-0966	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pkhd1	Rat	cell projection	located_in	IEA	UniProtKB-SubCell:SL-0280	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Pkhd1	Rat	centrosome	located_in	ISO	RGD:1318266	1624291	PMID:20554582	RGD	PMID:20554582
Pkhd1	Rat	centrosome	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	ciliary basal body	located_in	ISO	RGD:1318266	1624291	PMID:14978161, PMID:14983006	RGD	PMID:14978161\|PMID:14983006
Pkhd1	Rat	ciliary basal body	located_in	ISO	RGD:1318266\|UniProtKB:P08F94-1\|UniProtKB:P08F94-2	1624291		RGD	GO_REF:0000052
Pkhd1	Rat	ciliary basal body	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cilium	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cilium	located_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cilium	located_in	ISO	RGD:1318266\|UniProtKB:P08F94-1\|UniProtKB:P08F94-2	1624291		RGD	GO_REF:0000052
Pkhd1	Rat	cilium	located_in	ISO	RGD:1318266	1624291	PMID:15458427, PMID:16956880, PMID:17470460, PMID:20048263	RGD	PMID:15458427\|PMID:16956880\|PMID:17470460\|PMID:20048263
Pkhd1	Rat	cilium	located_in	ISO	RGD:1318267	1624291	PMID:16956880, PMID:17470460, PMID:18202188, PMID:22021705, PMID:28154160	RGD	PMID:16956880\|PMID:17470460\|PMID:18202188\|PMID:22021705\|PMID:28154160
Pkhd1	Rat	cytoplasm	located_in	ISO	RGD:1318266	1624291	PMID:20709014	RGD	PMID:20709014
Pkhd1	Rat	cytoplasm	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cytosol	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	cytosol	located_in	ISO	RGD:1318266\|UniProtKB:P08F94-1\|UniProtKB:P08F94-2	1624291		RGD	GO_REF:0000052
Pkhd1	Rat	endoplasmic reticulum	located_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	endoplasmic reticulum	located_in	ISO	RGD:1318267	1624291	PMID:28729032	RGD	PMID:28729032
Pkhd1	Rat	extracellular exosome	located_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	extracellular exosome	located_in	ISO	RGD:1318267	1624291	PMID:22021705	RGD	PMID:22021705
Pkhd1	Rat	Golgi apparatus	located_in	ISO	RGD:1318267	1624291	PMID:28729032	RGD	PMID:28729032
Pkhd1	Rat	Golgi apparatus	located_in	IEA	UniProtKB:E9PZ36\|ensembl:ENSMUSP00000085794	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Pkhd1	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pkhd1	Rat	mitotic spindle	located_in	ISO	RGD:1318266	1624291	PMID:20554582	RGD	PMID:20554582
Pkhd1	Rat	mitotic spindle	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	perinuclear region of cytoplasm	located_in	ISO	RGD:1318266	1624291	PMID:20709014	RGD	PMID:20709014
Pkhd1	Rat	perinuclear region of cytoplasm	located_in	IEA	UniProtKB:P08F94\|ensembl:ENSP00000360158	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Pkhd1	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Pkhd1	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pkhd1	Rat	protein binding	enables	ISO	RGD:1318267	1624291	PR:O35245\|PR:P61750\|UniProtKB:O75386\|UniProtKB:P49069 PMID:16243292, PMID:18235088, PMID:24586199, PMID:28154160	RGD	PMID:16243292\|PMID:18235088\|PMID:24586199\|PMID:28154160
Pkhd1	Rat	protein binding	enables	ISO	RGD:1318266	1624291	UniProtKB:P07602\|UniProtKB:P49069\|UniProtKB:P55258\|UniProtKB:Q13563 PMID:16243292, PMID:18235088, PMID:20048263, PMID:20709014	RGD	PMID:16243292\|PMID:18235088\|PMID:20048263\|PMID:20709014

#	Reference Title	Reference Citation
1.	Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations.	Furu L, etal., J Am Soc Nephrol. 2003 Aug;14(8):2004-14.
2.	Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1.	Gallagher AR, etal., Am J Pathol. 2008 Feb;172(2):417-29. doi: 10.2353/ajpath.2008.070381. Epub 2008 Jan 17.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Predominant extrahepatic biliary disease in autosomal recessive polycystic kidney disease: a new association.	Goilav B, etal., Pediatr Transplant. 2006 May;10(3):294-8.
5.	Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice.	Hiesberger T, etal., J Clin Invest. 2004 Mar;113(6):814-25.
6.	A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis.	Huang W, etal., J Immunol. 2018 Jan 1;200(1):147-162. doi: 10.4049/jimmunol.1701087. Epub 2017 Nov 20.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	A mouse model for cystic biliary dysgenesis in autosomal recessive polycystic kidney disease (ARPKD).	Moser M, etal., Hepatology. 2005 May;41(5):1113-21. doi: 10.1002/hep.20655.
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Comprehensive gene review and curation	RGD comprehensive gene curation
14.	Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney.	Shan D, etal., Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F463-F472. doi: 10.1152/ajprenal.00181.2018. Epub 2019 Jan 2.
15.	Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia.	Ward CJ, etal., Hum Mol Genet. 2003 Oct 15;12(20):2703-10. Epub 2003 Aug 12.
16.	The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.	Ward CJ, etal., Nat Genet 2002 Mar;30(3):259-69.
17.	A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation.	Woollard JR, etal., Kidney Int. 2007 Aug;72(3):328-36. doi: 10.1038/sj.ki.5002294. Epub 2007 May 23.
18.	Short article: Sequence variations of PKHD1 underlie congenital hepatic fibrosis in a Chinese family.	Yang N, etal., Eur J Gastroenterol Hepatol. 2019 Mar;31(3):363-367. doi: 10.1097/MEG.0000000000001295.
19.	PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells.	Zhang MZ, etal., Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2311-6.

PMID:14978161	PMID:15458427	PMID:15509540	PMID:16243292	PMID:16783394	PMID:17669261	PMID:18235088	PMID:19056867	PMID:19158352	PMID:19524688	PMID:19943112	PMID:20554582
PMID:20709014	PMID:21300060	PMID:25367197	PMID:26136112	PMID:28154160

Pkhd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	30,040,466 - 30,533,834 (-)	NCBI		GRCr8
mRatBN7.2	9	22,547,396 - 23,037,443 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	22,549,513 - 23,037,381 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	26,164,969 - 26,736,704 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	26,636,334 - 26,707,571 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	25,025,958 - 25,065,045 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	9	25,159,062 - 25,593,163 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	18,833,903 - 19,338,716 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	18,831,224 - 19,254,940 (-)	NCBI
Celera	9	20,127,204 - 20,618,569 (-)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

PKHD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	51,615,299 - 52,087,615 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	51,615,299 - 52,087,613 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	51,480,097 - 51,952,411 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	51,588,104 - 52,060,382 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	6	53,139,903 - 53,613,559 (-)	NCBI		Celera
Cytogenetic Map	6	p12.3-p12.2	NCBI
HuRef	6	51,314,936 - 51,783,413 (-)	NCBI		HuRef
CHM1_1	6	51,482,653 - 51,954,627 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	51,458,672 - 51,926,294 (-)	NCBI		T2T-CHM13v2.0

Pkhd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	20,128,003 - 20,688,306 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	20,128,003 - 20,688,288 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	20,057,779 - 20,618,082 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	20,057,779 - 20,618,064 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	20,047,860 - 20,608,138 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	20,042,930 - 20,603,208 (-)	NCBI		MGSCv36	mm8
Celera	1	19,948,411 - 20,498,116 (-)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.27	NCBI

Pkhd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	5,990,316 - 6,432,301 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	5,988,100 - 6,434,369 (+)	NCBI	ChiLan1.0	ChiLan1.0

PKHD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	66,083,287 - 66,550,385 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	61,960,485 - 62,427,247 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	51,166,516 - 51,635,057 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	52,435,455 - 52,903,309 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	52,435,462 - 52,903,309 (-)	Ensembl	panpan1.1		panPan2

PKHD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	19,280,866 - 19,744,669 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	19,286,822 - 19,744,141 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	19,173,042 - 19,651,204 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	19,781,225 - 20,253,821 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	19,783,877 - 20,243,554 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	19,289,289 - 19,759,402 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	19,392,649 - 19,862,367 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	19,530,405 - 20,000,289 (-)	NCBI		UU_Cfam_GSD_1.0

Pkhd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	54,799,690 - 55,229,420 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	8,730,842 - 9,159,863 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	8,730,766 - 9,160,102 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PKHD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	45,450,950 - 45,925,149 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	45,447,354 - 45,925,141 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	52,029,750 - 52,373,563 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PKHD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	20,411,746 - 20,873,601 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666044	51,528,670 - 51,991,959 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pkhd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624855	4,019,056 - 4,536,324 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624855	4,019,088 - 4,539,289 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Pkhd1
3655 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	12
Count of miRNA genes:	10
Interacting mature miRNAs:	11
Transcripts:	ENSRNOT00000060760
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	1254084	46254084	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	1254084	46254084	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5109826	42921101	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
724543	Cm20	Cardiac mass QTL 20	3.9		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	16961398	40594091	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	13533770	42791750	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat
1598823	Memor16	Memory QTL 16	1.9		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	22133322	49968732	Rat

D9Got30

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	22,911,264 - 22,911,504 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	26,612,243 - 26,612,482	NCBI	Rnor6.0
Rnor_5.0	9	25,469,745 - 25,469,984	UniSTS	Rnor5.0
RGSC_v3.4	9	19,203,614 - 19,203,854	RGD	RGSC3.4
RGSC_v3.4	9	19,203,615 - 19,203,854	UniSTS	RGSC3.4
RGSC_v3.1	9	19,200,937 - 19,201,176	RGD
Celera	9	20,492,634 - 20,492,873	UniSTS
RH 3.4 Map	9	212.1	UniSTS
RH 3.4 Map	9	212.1	RGD
RH 2.0 Map	9	174.6	RGD
Cytogenetic Map	9	q13	UniSTS

AU028005

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	22,862,453 - 22,862,619 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	26,563,227 - 26,563,392	NCBI	Rnor6.0
Rnor_5.0	9	25,421,225 - 25,421,390	UniSTS	Rnor5.0
RGSC_v3.4	9	19,154,986 - 19,155,151	UniSTS	RGSC3.4
Celera	9	20,444,082 - 20,444,247	UniSTS
Cytogenetic Map	9	q13	UniSTS

AU049041

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	22,626,409 - 22,626,629 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	26,326,879 - 26,327,096	NCBI	Rnor6.0
Rnor_5.0	9	25,182,167 - 25,182,384	UniSTS	Rnor5.0
RGSC_v3.4	9	18,913,421 - 18,913,638	UniSTS	RGSC3.4
Celera	9	20,208,062 - 20,208,263	UniSTS
Cytogenetic Map	9	q13	UniSTS

This gene Pkhd1 is modified in the following models/strains:

PCK-P2rx7^em8Mcwi

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_001070557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008757980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008757981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008757985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000080948 ⟹ ENSRNOP00000072399

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	22,549,513 - 23,037,381 (-)	Ensembl

RefSeq Acc Id:

XM_008766937 ⟹ XP_008765159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	30,040,466 - 30,533,834 (-)	NCBI
mRatBN7.2	9	22,547,396 - 23,037,443 (-)	NCBI
Rnor_6.0	9	26,164,969 - 26,736,704 (-)	NCBI

Sequence:

show sequence

TAAACTTGCCCTGTGGTCATTTTTGAACTTTTACTCTGGTGCACGTTTGGCCAGGCCAGAAACGAGTTAGGTGAGTTACACTCCAATATGAAGCGAGCTACCTGCATGGTAGCTAGCTAGCTGCAGGC
TGGCCCATCACCAGATAACGCGGCGTCATTTTGAAGGGACCGGTTTCTCTCATTTGAAGCACAAAGCGGACACAGCATCAGGCACAAAAGCTACATCATGCCAGTCGACCCTAAAAATGTGCTTCTAA
CATATGAGAGGTCTCAAGAGAGCTGAGCTACCCTGATGTGATGCCTGCCTGGCGGATCTCTCTGTTGAGTGTGGAACTACTACTTTTAGCAAATGCTTACTCAAGTTTCCGGATTGAACCGACAGAAG
GTAGCCTTGCAGGGGGAACATGGATCACACTTGTTTTTGACGGTTTGGAAACAAGTATTCTTTACCCCAACAATGGCTCTCAGCTGGCGATAGACCTGGTGAATGTGGCAACACCCGCCTTGAAGATC
CCTTGTGACATCTCTCCCCTCTTCGTGGATTTGCCCGTGGTGACGTGCCAGACGAGGTCTCTTCCATCAGAAGCACCTGAAGGTCTTTATTCTCTGGAGATACGCTCTGGGGATCAACTGCTAGGCAG
CCCGTGTGCCAGATTACTGGACAACTGTACTTTCAAGTTTTCCAAGGAGCAGACACCTGTTTTATATCAAGTTAACCCATCAAGTGGAGTTCCAGGAGAAGTAGTGCATGTGTATGGCTGGGTCATTA
CTGATCGGATGGAAATTTTTGATCCTGATGTGGACTACATGGAGAGCCCATTAATCCTGGAAGCTGGAGGAGACAAATGGCTTACTCCTTGTTCTCTTATAAACAGGAAGACAGGAATCTGTTTTCCC
ATCCAGGAGGAACATGGCCTTGGGACTGTGCAGTGTCGCGTGGAAGGCAGTTATATTGGTTCCCAGAATGTTAGTTTCTCAGTATTTAACAAAGGAAGGTCGATGGTGCATAAGGAAGCCTGGCTGAT
CAGTGCTAAACAGGAACTGTTCCTGTACCAGACATACCCAGAAATCCACTCTGTGTTTCCAAAAGTTGGGAGCCTTGGGGGAAGAACAGACATCACTATTACTGGAGATTTCTTTGACCCTTCTGCCC
GGGTTACCATTGCAGGCATTCCATGTGATATTAGACATGTGTCTCCCAGGAAGATTGAGTGCACCACCAGGGCTCCAGGAAATGGAGCAAGGCTCACTGCTCCCCAGGCAGGTAATCGAGGACTCCTT
TTTGAAGTTGGAAATGCTGTTAAGGATGAGGAGCTGACTGAAGCCACCCCAGGGTACAGGTGGCAGATAGTTCCTAATGCTAGTTCTCCATCTGGCTTTTGGTCCAAGGAAGGGAGACCTTTCAGAGC
ACGGCTCAGCGGGTTCTTCGTGGCTCCAGAGACCAACAATTACACATTCTGGATCCAGGCAGACAGCCAAGCTTTCTTGCGTTTCAGTTCTTCAGAGGAGCCAAGGATGAAGGTAGAAGTGGCTTCCA
TTGCAGTTGGCACTGCTGACTGGTTTGACTCTTGGGAGCAGAACGGGAATGAAGGGAGCTGGCAACAGAAGACAAATAAGCTAGAACTGCAGGGCGGAGCCAAGTACTACTTGGAAGCAGAGCAGCAT
GGGATAGCTCCCAGCAGGGGGATGAGAATTGCTGTCCAGATCCACAACACCTGGCTGAATCCAGATGTGGTCAACACTTACCTTCTGGAGAAACACCAGATCCGAGCCCAAGCCCAGAGACTTCCAGA
AATACAGGTGTTGAACATGTCAGGTAAAGGAAACTTTTTCCTTACTTGGGGCAATGTCTCCAGCCAACCAGTTCCTGCAAATGCCACAGCCCAACAGATCCAAACCATCATCGAGGAGTTGCTGGTGG
TGAAATGCAATCTGGTACCCCTTTCAGCTCGTGTTCTCCTCTGGCTTGGATTTGAGCAAGGCTTAGATGGCTCCAGGTCTGATGGGGTCCTCACCAGTTCAACCGAACCATTCTGTGGCAGATTCAGC
CTTGGTCAACTTCGACATCTTATCCTAAGCCCTGGGGCTGTCAGTAAGGGCTATCAGCTGGATCGATACCCATATTTGTGCTTTGCATACAGAGGTCATATGAACAGGACCCTGGACATGACTGTTTC
TTTCCTATTTGGCTTCCAAAATGTCATGAAGAATATCACCTGTGACTGGAGTCTGATGGAACCCCACCCTGAGAGCTGGCACTTTACTTGCAATAACCTCTGGGACACATGTGTACGCCATTCTGAGG
AGCTCCAGTCTTCTCTGGCAAACACCCCATTGCTGGTTCATCGGATCGACATCTTCCCTGTGGTTCCAGAGGCAGACTTGCTCTATGTGGATGAAATTATTCTTGCAGATACCAACGTAACAGTTTCT
CAAGCCGATTCTGGAGTAGCCCGCCCAGGTGGGAATGTGGTGGAGTCAGTGTCTGTGGTGGGAGTCCCTCCAGTCTACAGCATAGCCTCTTGGATGGCAGGATGTGGCTCAGAACTTCCTCTCATCAC
TGCATGCTATGTGCCCACCCAGGGGACAGGCGAAGGATCAGAACTGATTGAGGTGACAGCGAAAAGACTCCAGAGGACAAGCCCACCTTTGGGAGGACACTTCTCCCTCCACCTCTCTGATACAGTGA
TACCTGATGTTCCAGTGCATGTGTCTGCCAGACAGCTTCATAAGCTACTGCAGGACAATGCTGATGAGTCCACATCTGGATATCTCAATGCCGATGACTTCATTGTGACAAAGGATCAAAATTCCTGC
TATGAACATGTGTGGACTCTTTCCTGGACCACTCAGATTGGGGATTTGCCCAATTTCATCAGGGTCTCCGATCAAAATCTTACGGGGTTGAATCCCACCATAACTGCTCGTGTAGTATACGATGGCGG
AGTTTTCCTTGGGCCCATTCTTGGAGACACACTGGCTACTGCCAACCAGCAGACTCAGGTGACTGTACAAGTGAATGACATACCAGCCCATTGTTCAGGCTCCTGCTCCTTCCAATACCAGCGAGCGT
CAACTCCCAGCGTGGACTGTGTGTGGTATTCCCTTGGTAGTGATGTCAACCTGCTGGTTCATTTTACTGGAAATGGTTTCCCTAGAGATGCCCAGTTCTTACAGGTCACGGTGATCAACACGAGTTGT
GAAGTTATTTTCTCAAATGAAACCAACGTTGCCTGTGAGCTTGCCCTACTACCAGTTGGAGTGCACCGGGTTTTTATGCTGGTGAGACCTTCTGGCCTTGCTCTTAATGCCAGTGGAGAAGGCCTCTT
CCTACGTGTGGAACCCAGGCTGGATGCTGTGGAGCCTTCTACAGGCGCAGAGATTGGAGGATGGTGGGTTACACTCCGAGGCTCTAGTCTAGAAGGCGTTAGCCTGGTGTTATTTGGAACTCGGTCGT
GTGTCATTGATGTCATTAGAAGCAATTCGCAACAGATTCAATGCAAAGTCCCACCTAGGGGGAAAGATGGATACACTGTGAATGTGACTGTGATCAATGGGGACCACTCCACAGTTCTTGCCAGAGCA
TTTACTTATGTCTCCTCTTTAAATCCAGTGATTGTGTCTTTGAGCAGAAATAGAAGCAACATAGCAGGAGGTGAGATTCTGTTCCTTGGGATGACACTGATGGTGAACTATACAGATCTGAATGTGCA
AATCTACATTCAGAACACTTCTGCTCAGGTCCTTGCAAAGACGGCATGGGGACTGGAGGTGCTGTTGCCTCCGTTGCTGCCTGGCATCTATGTGATTTCAGCATTCATCAATGGAATCAGCATTCGTT
CACAAGGGGTTGATCTCCACATCCAGTACCTCACTGAAGTTTTCAGCATGGAACCTTGCTCCGGGTCTCTCTTGGGTGGAACTATCCTCCAGACTCTCAGGAGCAGGACTGGCAGAGACCCAGCTCTG
ATTCGGGTGCTTGTGGACAACCGTCTTGCTTGTGATACTGTGAAGTTAACAGAAGTGAACATTGGTGTGAGACTCCCGAGTCTACTACCACCCAGAGCAGATGTTCTCACTGTCCCAGCATCTGTGGA
GATCTGGGCTGGCAACACTTCCTTCGTGGGGAAGGCCTTCCATCTTCACATATGAAGCTGCAGCCAACTCCCAGTGGTCACTGCCTATGGGGGGGTGAACTCCATTGAACAACAGTGTTAAGGTTTAT
GTGGAAGAAATAACCTCTCCGACTCAGTCATTCTTTTGGGATCCCTTGAAATGGACCTTCAAGTGCAATTGTTTGGGATAACATGAACCTGTCTGGGCTCCCTTCTTCTCCACAGTTTGGAAGCTGGG
NTCTATGCTCTCCAAGTTCGTCACNAGAGAGGATGGTTTGCCAATATGTCTGCGGTGCTCAGAAGTTTGAGGCTGTCACCGCAGATTATCGACATCTTCCCANCACATGGTTCATAATATGGTGGGAC
AGTGCTTACTGTGAAGGGCACGGCTTTCAGGTCCAGAAGGAGGGTCTGTTCATGTGACCTTTCAGGTCCTTTTACTTGCGGGATTTTGAGTTTGGGAGACCACAACAGTCCTAGCCAGACCAAGTTTG
TGGGTGATCAGTTTTCTGAAACATCANCTGCTCTAAACATCACAGTTCATGGCAATGGGCTGACCAGCAAGTGTGAGGGGAACTGTACTCTCTTCCTGGAGGAAGCAGCAACTCCTATTGTGGATGCT
TTGACTATAAGTATCAGTGGCTCTCTAACCACAGTGCTGATGAGAGGACAGAGGTTAGGCTCTGCTGGTGAGCCAACAGCCTTTGTGGATGGTCAACTTCTTTGCCATACAACTTTCTTTAATACCAG
CTATGTGGCATGCCAGATGAGAGATTTGGCCCCGGGGTTCCACTATCTGTCAGCTGTTCGTACAAGTGCTGGATATGCTTGCCTCAATAGTGTTTCTAGAAACTTCTTCGTTGTGCCTCAGGTGTTCG
ATTATTTTCCTAAGGATTTTAGCATCCATGGTGGAAGTCTCTTGACTATAAAAGGCACAACCCTTCGAGGATGGAAAACTACATTTGTCTATGTTGGCCAGCAGGCTTGTCTAACAGTGAACATCAGT
TCTGAGTTCATCCAGTGCATTGTTCCCGCAGGAAATGGCTCTGCTGCTCTGGAAATAGATGTAGATGGAGTTTTATACCACATGGGATTTGTTGACTACAGCAGCATCTTTACCCCAGAATTGCTTTC
TGTTTCACGGAGTCATGACATCTTGACCTTTACAGTGGCCCGGATCTCAGGGGCTGCAAATGTTGACATTCTTATTGGGACGTCACCGTGTCTAGATGTTGCTGGTAACCGTACGATTCTCCGGTGCA
TGGTCCCTCTGCTTCCTGCTGGGGAGTATGCTGTCACAGGTTATGACCACAGCAGAGGATGGGTCTCATCCACTCTCATTCTCGTGCTGAGAGCCACTGTGACCTCAGTGACTGAGAACTATGGCTGC
CTGGGTGGAAGGCTTTTGCATGTGCTCGGAGCAGGATTTTCTCCAGGGAACATCTCAGCTGCTGTATGTGGTGCTCCGTGCCAAGTCTTGGCTAATGCGACAGTGTCTGCCTTCAGCTGCTTGGTTCT
GCCCCTGGATGCGTCCTTGGCTTTCCTCTGTAACCTGAGGCATGCAGAAGACAGCTGTGGAGTTAGCAGGCCCACCTACTTGCAATGTGACTTGACTGTCTCCGTGGGGATGGAGAGACTGCCTGGAT
CCTGGCCTTACGTCTACCTTTGTGAAGAGAGTTCCCAGGGCCTCTTCGTACCAGATCACCAGATCTTCCTTTCCTTCTCAGGCCTCTTCCTCAGCCCTAAAGTGGAAAGAGATGAAGTTCTCATCTAT
AATAGCTCCTGTAACATTACCATGGAAACTGAGGCAGAGATGGAGTGCGGGACACCTAATCAGCCAATTACCGCCAAGATTACTGAAATACAGAAAAGCCGGGGCCAGAACACTCAGGGCAACTTTTC
CTTCCAATTCTGCCGAAGGTGGTCCAGGCCTCACAGTTGGTTTCCTCACAGAGTGCCACAAGATGGCGACAATGTCACAGTGGAGACCAGTCACCTGCTACTGCTAGATGCGAATACAAGTCTCCTGA
ACTCCCTGCACATTAAAGGTGGCAAGCTGATTTTCATGGAGCCCGGACCCATTGATCTCAGAGCCCATTCTATCCTAATTACAGACGGTGGAGAGCTCCATATTGGATCTGAGGACAAGCCTTTCCAA
GGCAAAGCTCGGATCAAACTCTATGGAAGTGTCCACTCCACTTCCTTCTTTCCCTATGGAGTCAAGTTCCTGGCTGTGAGGAATGGAACTCTTTCTCTGCATGGTTCTGTTCCAGAAGTTACTTTTAC
CTATCTTCGAGCAGCTGCATGTGCAGGAGACACCGTGTTGGCTCTGGAAGAGGCCGTGGCTTGGCACCCTGGGGATGAGGCTGTCATTAGCAGTGGAGCGACTGTAGAAGGTGCTGAAGCAACAGAAG
AGGTGGTTGTTGTAGAAACTGTCCACGATGCGGACCTCCATCTCAGGAACCCCCTGAGATACTCCTACAACTTCACAGAAAACTGGGTAACTGGAGTGAATCATATTTTGAAGGCTACAGTGGCTCTT
CTCAGCAGGAACATTATTGTCCAAGGAAATCTCACTCTCGAGAGGGTAAAGCTTCTTGATTCATGCCAGGAGGCCGGTGCTGCTGAAGGAAACCTGAAGCATTGTTTATATTCTAAGAGTGAGAAGAT
GCTGGGAGCCAGGAATCTGGGGGCCAGAGTTATCATTCAGTCCTTCCCAGAGGAACCCAGCTTGGTCAAGCTGAAGGGAGTGCAGTTCCGAGACCTGGGACAAGCCTTCCATAAGCATCTAAGCTCAC
TCACCCTGGTGGGAGCTATGAGAGGTTCTTATCTCCACAGCTGTTCAATGTGGGGCTCCTTCAGCAGAGGCCTCAGCATACACAGGACCTGGGGTCTGAAGGTGGAAAATAATATATTCTATAAGATT
GTAGGTCATGCCCTACTGGTGGGGTCCTACATGGACAGAAGTTTTAGCACTAGTGAGGCTGTTATTGGAAGAAAAAATGGTTGGTGGGAAGAGGGAAGTATGATAAGAAACAATGTGATCATCAATGT
TTCTGGGGCTGAGGGACTGTCCAGTTCTGAAATGTTGGCACCAGCAGGCATCTACACTTTCAGTCCCACCAGTGCGATTGAGGGCAACAGAGTGTGTGCAGCTGGTTATGGCTATGTTCTCCACCTTG
TGACCAGCCAAACAGTGCAAGCTCCACTACTCTCATTCAACTGGAATACTGCACATTCTTGTACAAGATATGGTCTCCTTGTATATCCTGAATTTCAACCGCCTTGGAATAATGACACTGGCTTCACT
CTGTTTCAAAACTTCATGGTTTGGGGAAGTGCTGGTGGTGCCCAGATTTTTAGAAGTAACAATCTGCACCTGAGAAACTTCCAAGTTTATGCATGCAGAGACTTTGGGATTGACATTTTGGAAAGTGA
CACGAACACTTTGGTTACTGACAGCTTCTTACTAGGTCACTTCACCCACGAGGGAAGTCTATGTATGTCAGTTGGCATCAAAACTCCCAAAAGATGGGGACTGACGATTTCTAACACAACTTTCGTTA
ATTTTGATCTCAACTGTGTGGCCATCAGAACCTGTTCTGGCTGTTCCCAAGGACAGGGTGGATTTCCTGTCAAGACCAGGCAATTGAAGTTTGTCAACTCTTCAAATTTAGTAGCATTTCCTTTTCCT
CATGCAGCAGTTTTGCAAGACTTAGATGGGTCCCTGTCTGGGAAAAATGGATCTCATGTTCTTGCTTCTATGGAAACCCTCTCAGACACATGTTTGACCAATGCAAGCTTCAGCCAGATTGTCTCTGG
CAGCGTCTGTGGGGAAGCTGTTCTCTTCCATCGTATGTCTATTGGTTTAGCTAAGAGCCTCGACGTTCCTAAGAATTTAACCATGACTGACATCAGAAATAGGACAATCACTATCAATTATGTGGATG
ACACGTTGTCTAACTCTTATGGCTGGATGGCTCTACTCTTGGACCAAGAGACCTACTTGCTGCAGTTTGAGGGTCCTTGGACGGACGGATCTTTGCAGTACTCAGCAACCTTTGACAACTTTGCCCCT
GGAAATTACCTCCTGCTAATGCACAGGGACCTACTACCTTATCCCGACATTCTCCTCAGATGTGGGAGTCGGGTGGGCCAGTCACTTCCCTCTCATCCTTTGCCGAGTCGAGACGGAGCCTGTGATTG
GTTCTTCCACAGGCAGTTAAGGCAGCTCACCTACCTGGTTTCAGGGGAAGGTCAAGTTCACGTATTCCTCCAGGTGAAGCATGGTGCACCTCCAACTGTTTCAGCTTCTACATCTGTATCTGAATCAG
CTTTAAAATGGTCCCTTCCTGAAACATGGCAAGATGTTGAAAAAGGCTGGGGAGGATACAACCACACCATCCCAGGACCCGGTGATGACGTCTTGATTTTACCCAACAAGACGGTTCTTGTGGATACT
GATCTCCCCGTGCTTAGATGCCTCTATGTGATGGGTACCTTAGAATTCCCTGTGGACAGAAGCAACGTTCTGAGTGTGGCGTGCTTACTCATTGCAGGAGGGGAGCTGAAAGTAGGTACTTTGGAAAA
CCCCTTAGGAAAAGACCAAAGACTTCTGATACTCCTCAGAGCCTCAGAAGAAATCTTCTGTGACCGTTTTGACGGAATACGTGTTGACCCTGGAACAATTGGAGTTTATGGGAAACTTCGCCTTCACA
GCGCATATCCTAAGAAATCCTGGGTACACCTTGGAGCTGACATTGCCCCGGGAAATGAGAGGATTATAGTACATAATGCAGTGGATTGGCAGCCCCATGACAAAATCGTCCTCAGCTCTTCTTCTTAT
GAGCCTCATGAGGCAGAGGTCNCCACTGTGAAGGAAGTCAAGGACCATCACATCAGGATCTATGAACGTNCTAAACACAGGCACATTGGAAGTGCCCACACCCTGGAGGATAGTCGACAGATTTGTTT
GGCTGCTGAGGTTGGATTGTTGACCAGAAACATTAGAATTCAGTCTGACTCATCCTGTAGAGGGAGACTCCTTGTGGGGTCCTTCAGGAAATCTAGCGGAGAAGAGTTTTCTGGCATTCTTCAACTTC
TAAATGTAGAAATTCAAAACATGGGGTCACCACTGTATGCATCTATTGAATTCACCGGTGTGTCAGCTGGATCCTGGGTTATATCTTCTACTGTACATCAAAGCTGCACTGTGGGCATCCATGCATCT
TCTAGTCGTGGGATGGTCTTAAATGACAACATAGTGTTTGGCACAAAAGGCCATGGAATCGATGTGGAGGGTCAGAACTATTCTCTCACCAATAACCTTGTCATTCTGTCAATGCAGTCAGCAAACTC
CCTTCCTTGGGTGGCAGGAATCAAAGTGAACTATGCCGAAGATATCATTCTCCACGGCAATGTGGTGGCAGGATCTGAGAGACTTGGCTTTCATGTCCGTGGCCATGGGTGCTCCTCTGAAGTGCTTT
GGTCTGACAATGTGGTCCACTCAAGCCTCCATGGCATTCACCTCTACAAGAAACGTGAACCTAATAACTGTACTGGTGTCTCTGGATTTCTGGCTTTTAAGAACTTTGACTATGGTGCCATGGTTCAG
ACAGAGAATAGTGTGGACATACAGAATATCACTCTGGTGGATAATACTGTTGGTCTTTTGGCCATCTCGTATGTATCTTCGGCTCCACTGAGATCTGGCAGCACTCTACAGATTACTCTTAGGAATTC
AGTCATCGTAGCCACTAGCTCCTCTTTTGACTGCATCCAAGACAGAAAGGCTCCTCAGTCGGCCAACTGGACCTCCACAGATAGAGCGCCTTCCAATCCCAGAGGAGGCCGGATCGGTATTCTGTGGC
CTGTATCTGCCTCAGAACCAAATGGATGGCCCCAGGAGCCATGGCACAAAGTAAGGGGCGGTCATTCAGTTCCAGGAATTATGAAGCTTCAAGATGTCACCTTTTCTAGTTTCGTGAAGAGTTGCTAT
AGCGACGATCTGGATGTCTGCATCCTGACTAATGAGCACAGCACTGGAATCATGTACCCAATAACAGCAGAGAGGACCAGAATGCTGAAGATAAAGGACAAAAACAAGTTCTACTTTCTTCCATTACA
GTCTGGGAAAGACTTAGTGGGAACCATCTGCCCTGCATCATCGGACTGTGAAATTCCAAGAAAATACCTCTTCACAGATCTGGATGGGAGAACCCTGGGTCTGTCCCCACCAGTTTCTGTGTTTCCAA
GGATAGAGGAAGGATGGACTGGATCCTTCTTCAACACAGGTATATTCAGAGAAGAACAGAAATGCACATTTCGAGCCATGATCCAGGGCTTCTTCTGTAAGCAGACTGAGCATGCAGTCCTAATTCTT
GATAATGTTGATGTAACTTGGACAATCCCCAAATTCTACCCACTTGTATCCATTACTAATGGTTTTGTGGACACGTTCAGTATTGTGAAGGACAGTGGTCTATGCTTTCCCACAAGCTCCCCGTCTAC
TTTTTATTCCATTTTACCAACCAGACAAATGACCAAAGTATGCTTTCCAGAGCGAACTCCCCCATTCCTGCACTTTTTTCTACTGGCAAACAGAAGAGCGTCCAAGCTCATCTTGGCTGTGTTCTACA
ATGAGATTCAGAGCCCCTACGTTTTCTTAGACAAGAGCTTTATTCCACCTACACCAGTAGAGTCAGCATTTTCACTGTTGGATGAGCCTGTTGGTGCCAACTATTTCGACATCATGAATAACCTCTTG
TATGTTGTCCTGCAAGGAGAGGAGGCTGTTGAAATACGTTCAAGTGTTTCCATTCATTTGGCTTTGACAGTGACATTTTCAGTCCTAGAAAAGGGCTGGGAGAAAGCAGTGCTTGAAAGTCTAAGAGG
CTTCTTCCAGATTGACCAAAACCAAATCAGACTCACTCTTGAGATGCCTGGCAACAAAGAGACCTTAAAGGCCATTGCAAACAGTGAAGGAAAACGAAAGCGCAGTTGCCCAACTGTGACTTGTGCTG
TCCCTTCTAGCAGATATGTTCAACGCAGACCTCTCATGGCAGAAATGGCATCATTTACAATCACACCAGCAACCACTCTGGAAACTTTCTCAAAGGTGATTGTCTTTGAAATCGGTGATCTGCCAAAT
GCAAGGGACAGTGAATTCATTCAGTCCTTACCAAGTAACAGATTACAGAAATTGGCTCACCAGGTTATCACTGCTCAACAGACTGGAGTTCTGGAAAATGTCCTTGGTATGACTGTTGGGGCCCTACT
AGTGGCTCAGTCAGAGGGAGTCACAGGATATAGAAATGCAAGTAGTTTAATAACTGGAAACCAGATATATACCCGGCCCTCTGTGGTTTCCATCCTGGTGCAGCCTTCAGATGGGGAAGTGGGAATAG
AATTACCGATTCAGCCACGGCTCATCTTCCTGGATGAGAAGAATGAGAGAGTGGAAGCTTTGGGTCTCCCCTCAGAACCTTGGATTATTTCAGTTTCCCTGGAAGGGACATCTGAATCAATGCTAAAA
GGGTGTACCCAGGCAGAAACACAGGATGGCTATGTGACCTTCTCCAGATTGGCTGTCTTGACCTCTGGGTCAAACTGGCACTTAGTTTTTACTGTCACTTTCCCTCCAGGTACTAATTTAACAGCTCG
ATCCAAGACCTTTGCTGTCCTGCCTGTGGCCGGCAAGGAGAGGTCAACTATCATCCTGGCCTTGTCCCTGTGCTCAGTGGCGTCTTGGGTGGCTCTAAGTTGTCTCATTTGCTGCTGGTTTAAGAAAA
GCAAAACCAGAAAAATAAAACCAGAAGACATATCTGAATCCCAGGCTAAGGAACAAAAGAAGAATACCCATATCTCTTCCAAACCCAGAGAACTACAAGTAAAGACCGCAAAAGAAGACGCTATGATG
GGAGAAGACATGAGAATGAAGGTCATGGAGGGAAGGCAGAACCAGTTTTCCCAACACTCAATGGATGGAGTGTCCAAAAGAAAAGTTAGCCGCCGTGCTGTCCCAGAGGAAAGAACAGCTACACCTGC
CCTGAAGATTCCCAGAACCACCTGTGTCCCAGGAGCTCTTCCTCAGCAGTTGACTCTGCCGGAGCCTGGGAACTGGCAGGAGGCCCAACAGCAGCTGCTTAGATACCAGCTGGCAGGCCGCGATCAGC
TGCTTCTGTTATGCCCAGACCTCAGGCAAGAGAGGCAGCAGGGTCAGGAGCCTAGCCAGCTGAACAAAGGGAGTGGCCGCTGCATGGGGCTGTCTCAAGAGAAGGCCACTTGCGTTCCCACTGAGACC
TTCTGCCTTCACACAGCTCCACCAGAAACTATCCAGTAACAGCTGTGGGCGCGGAGCACTGTGGGCGTTTGTATGAAAAGGAGAAACTGTTCAAAATTATTTCTACATGGTGAACGGGGGAGGAGAGG
TCTGATCTGTTTGGACAACTAAGGGAGAATGGGGACGACTGTAATTAAGCTTCTCTTAGAGCCAACACTCAGGATGCTTCAGGCTTGTCTTATGGAAGACCTGTGATAGATTTAGTTAGCTGATGTTG
TATCTGCAGGACTACAGAAATACTCAGGAGATATCTTACACCAAAGCTTATCCCCCAAACAGAGGTAACGTAATAAGAGTTACTTGTAGATTTTATTTCGTGGTTTAAATTTAGTAATTATTGGGAGC
TTTCTGCATTGCAAGCATTATTATTTGCACCTCATGAGTATTTGTACATGAAAGATGATGGTCACATAGGCTTTGTTGGGATTTCAGTTAAGAAAAAGATATGAAAACACTAAATTTAGGCAATTTTT
ATGTACTATAGGTACATTTCACACCAGGTATTTATATGAAAAGGGGAAATATTCAAAGCTACTTCTCTGTGGTAAGTGGGAAAAGAGAGGTCTGATCTGTTTGGACAACTAAGGGAAAAATGTGGACT
CTCAATATTTTGACTTAATAGTTCTAATAATTTCTTCTAGTTGGGTAAAATTTACAACTACCAGGGAATTTTTCTAGAAGACTAAACATAATCTAATGGTAAAGTGGACTAATGGCTCTCTTATTTAT
CAGAGAACTGATTTTTGTTTCCCACAAAAAGCAAGTATAAGGAGTGCCCAAGAGACTAGAAAAGAAATCTTAGGTATGGTCTTTTGAAGCTGTGTTTAGGGAGATGAAGCAAAGAGGTAGCTGATGCT
TTAAGAAAGAA

hide sequence


Protein RefSeqs	XP_008765159	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072399
	ENSRNOP00000072399.2

RefSeq Acc Id:

XP_008765159 ⟸ XM_008766937

- UniProtKB:

A0A0G2K2W1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPAWRISLLSVELLLLANAYSSFRIEPTEGSLAGGTWITLVFDGLETSILYPNNGSQLAIDLVNVATPALKIPCDISPLFVDLPVVTCQTRSLPSEAPEGLYSLEIRSGDQLLGSPCARLLDNCTFKF
SKEQTPVLYQVNPSSGVPGEVVHVYGWVITDRMEIFDPDVDYMESPLILEAGGDKWLTPCSLINRKTGICFPIQEEHGLGTVQCRVEGSYIGSQNVSFSVFNKGRSMVHKEAWLISAKQELFLYQTYP
EIHSVFPKVGSLGGRTDITITGDFFDPSARVTIAGIPCDIRHVSPRKIECTTRAPGNGARLTAPQAGNRGLLFEVGNAVKDEELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPETNN
YTFWIQADSQAFLRFSSSEEPRMKVEVASIAVGTADWFDSWEQNGNEGSWQQKTNKLELQGGAKYYLEAEQHGIAPSRGMRIAVQIHNTWLNPDVVNTYLLEKHQIRAQAQRLPEIQVLNMSGKGNFF
LTWGNVSSQPVPANATAQQIQTIIEELLVVKCNLVPLSARVLLWLGFEQGLDGSRSDGVLTSSTEPFCGRFSLGQLRHLILSPGAVSKGYQLDRYPYLCFAYRGHMNRTLDMTVSFLFGFQNVMKNIT
CDWSLMEPHPESWHFTCNNLWDTCVRHSEELQSSLANTPLLVHRIDIFPVVPEADLLYVDEIILADTNVTVSQADSGVARPGGNVVESVSVVGVPPVYSIASWMAGCGSELPLITACYVPTQGTGEGS
ELIEVTAKRLQRTSPPLGGHFSLHLSDTVIPDVPVHVSARQLHKLLQDNADESTSGYLNADDFIVTKDQNSCYEHVWTLSWTTQIGDLPNFIRVSDQNLTGLNPTITARVVYDGGVFLGPILGDTLAT
ANQQTQVTVQVNDIPAHCSGSCSFQYQRASTPSVDCVWYSLGSDVNLLVHFTGNGFPRDAQFLQVTVINTSCEVIFSNETNVACELALLPVGVHRVFMLVRPSGLALNASGEGLFLRVEPRLDAVEPS
TGAEIGGWWVTLRGSSLEGVSLVLFGTRSCVIDVIRSNSQQIQCKVPPRGKDGYTVNVTVINGDHSTVLARAFTYVSSLNPVIVSLSRNRSNIAGGEILFLGMTLMVNYTDLNVQIYIQNTSAQVLAK
TAWGLEVLLPPLLPGIYVISAFINGISIRSQGVDLHIQYLTEVFSMEPCSGSLLGGTILQTLRSRTGRDPALIRVLVDNRLACDTVKLTEVNIGVRLPSLLPPRADVLTVPASVEIWAGNTSFVGKAF
HLHIXSCSQLPVVTAYGGVNSIEQQCXGLCGRNNLSDSVILLGSLEMDLQVQLFGITXTCLGSLLLHSLEAGXYALQVRHXRGWFANMSAVLRSLRLSPQIIDIFPXHGSXYGGTVLTVKGTAFRSRR
RVCSCDLSGPFTCGILSLGDHNSPSQTKFVGDQFSETSXALNITVHGNGLTSKCEGNCTLFLEEAATPIVDALTISISGSLTTVLMRGQRLGSAGEPTAFVDGQLLCHTTFFNTSYVACQMRDLAPGF
HYLSAVRTSAGYACLNSVSRNFFVVPQVFDYFPKDFSIHGGSLLTIKGTTLRGWKTTFVYVGQQACLTVNISSEFIQCIVPAGNGSAALEIDVDGVLYHMGFVDYSSIFTPELLSVSRSHDILTFTVA
RISGAANVDILIGTSPCLDVAGNRTILRCMVPLLPAGEYAVTGYDHSRGWVSSTLILVLRATVTSVTENYGCLGGRLLHVLGAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDASLAFLCNLR
HAEDSCGVSRPTYLQCDLTVSVGMERLPGSWPYVYLCEESSQGLFVPDHQIFLSFSGLFLSPKVERDEVLIYNSSCNITMETEAEMECGTPNQPITAKITEIQKSRGQNTQGNFSFQFCRRWSRPHSW
FPHRVPQDGDNVTVETSHLLLLDANTSLLNSLHIKGGKLIFMEPGPIDLRAHSILITDGGELHIGSEDKPFQGKARIKLYGSVHSTSFFPYGVKFLAVRNGTLSLHGSVPEVTFTYLRAAACAGDTVL
ALEEAVAWHPGDEAVISSGATVEGAEATEEVVVVETVHDADLHLRNPLRYSYNFTENWVTGVNHILKATVALLSRNIIVQGNLTLERVKLLDSCQEAGAAEGNLKHCLYSKSEKMLGARNLGARVIIQ
SFPEEPSLVKLKGVQFRDLGQAFHKHLSSLTLVGAMRGSYLHSCSMWGSFSRGLSIHRTWGLKVENNIFYKIVGHALLVGSYMDRSFSTSEAVIGRKNGWWEEGSMIRNNVIINVSGAEGLSSSEMLA
PAGIYTFSPTSAIEGNRVCAAGYGYVLHLVTSQTVQAPLLSFNWNTAHSCTRYGLLVYPEFQPPWNNDTGFTLFQNFMVWGSAGGAQIFRSNNLHLRNFQVYACRDFGIDILESDTNTLVTDSFLLGH
FTHEGSLCMSVGIKTPKRWGLTISNTTFVNFDLNCVAIRTCSGCSQGQGGFPVKTRQLKFVNSSNLVAFPFPHAAVLQDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVSGSVCGEAVLFHRMS
IGLAKSLDVPKNLTMTDIRNRTITINYVDDTLSNSYGWMALLLDQETYLLQFEGPWTDGSLQYSATFDNFAPGNYLLLMHRDLLPYPDILLRCGSRVGQSLPSHPLPSRDGACDWFFHRQLRQLTYLV
SGEGQVHVFLQVKHGAPPTVSASTSVSESALKWSLPETWQDVEKGWGGYNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLEFPVDRSNVLSVACLLIAGGELKVGTLENPLGKDQRLLILLR
ASEEIFCDRFDGIRVDPGTIGVYGKLRLHSAYPKKSWVHLGADIAPGNERIIVHNAVDWQPHDKIVLSSSSYEPHEAEVXTVKEVKDHHIRIYERXKHRHIGSAHTLEDSRQICLAAEVGLLTRNIRI
QSDSSCRGRLLVGSFRKSSGEEFSGILQLLNVEIQNMGSPLYASIEFTGVSAGSWVISSTVHQSCTVGIHASSSRGMVLNDNIVFGTKGHGIDVEGQNYSLTNNLVILSMQSANSLPWVAGIKVNYAE
DIILHGNVVAGSERLGFHVRGHGCSSEVLWSDNVVHSSLHGIHLYKKREPNNCTGVSGFLAFKNFDYGAMVQTENSVDIQNITLVDNTVGLLAISYVSSAPLRSGSTLQITLRNSVIVATSSSFDCIQ
DRKAPQSANWTSTDRAPSNPRGGRIGILWPVSASEPNGWPQEPWHKVRGGHSVPGIMKLQDVTFSSFVKSCYSDDLDVCILTNEHSTGIMYPITAERTRMLKIKDKNKFYFLPLQSGKDLVGTICPAS
SDCEIPRKYLFTDLDGRTLGLSPPVSVFPRIEEGWTGSFFNTGIFREEQKCTFRAMIQGFFCKQTEHAVLILDNVDVTWTIPKFYPLVSITNGFVDTFSIVKDSGLCFPTSSPSTFYSILPTRQMTKV
CFPERTPPFLHFFLLANRRASKLILAVFYNEIQSPYVFLDKSFIPPTPVESAFSLLDEPVGANYFDIMNNLLYVVLQGEEAVEIRSSVSIHLALTVTFSVLEKGWEKAVLESLRGFFQIDQNQIRLTL
EMPGNKETLKAIANSEGKRKRSCPTVTCAVPSSRYVQRRPLMAEMASFTITPATTLETFSKVIVFEIGDLPNARDSEFIQSLPSNRLQKLAHQVITAQQTGVLENVLGMTVGALLVAQSEGVTGYRNA
SSLITGNQIYTRPSVVSILVQPSDGEVGIELPIQPRLIFLDEKNERVEALGLPSEPWIISVSLEGTSESMLKGCTQAETQDGYVTFSRLAVLTSGSNWHLVFTVTFPPGTNLTARSKTFAVLPVAGKE
RSTIILALSLCSVASWVALSCLICCWFKKSKTRKIKPEDISESQAKEQKKNTHISSKPRELQVKTAKEDAMMGEDMRMKVMEGRQNQFSQHSMDGVSKRKVSRRAVPEERTATPALKIPRTTCVPGAL
PQQLTLPEPGNWQEAQQQLLRYQLAGRDQLLLLCPDLRQERQQGQEPSQLNKGSGRCMGLSQEKATCVPTETFCLHTAPPETIQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000072399 ⟸ ENSRNOT00000080948

Protein Domains

G8 PA14

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K2W1-F1-model_v2	AlphaFold	A0A0G2K2W1	1-1613	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-28044	BioCyc
Ensembl Genes	ENSRNOG00000058742	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000080948	ENTREZGENE
	ENSRNOT00000080948.2	UniProtKB/TrEMBL
Gene3D-CATH	2.160.20.10	UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/TrEMBL
InterPro	Beta_helix	UniProtKB/TrEMBL
	Fibrocystin-related	UniProtKB/TrEMBL
	G8_domain	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/TrEMBL
	IPT_dom	UniProtKB/TrEMBL
	PA14/GLEYA	UniProtKB/TrEMBL
	PbH1	UniProtKB/TrEMBL
	Pectin_lyas_fold	UniProtKB/TrEMBL
	Pectin_lyase_fold/virulence	UniProtKB/TrEMBL
NCBI Gene	301287	ENTREZGENE
PANTHER	POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1	UniProtKB/TrEMBL
	PTHR46769:SF1	UniProtKB/TrEMBL
Pfam	Beta_helix	UniProtKB/TrEMBL
	PF10162	UniProtKB/TrEMBL
	TIG	UniProtKB/TrEMBL
PhenoGen	Pkhd1	PhenoGen
PROSITE	PA14	UniProtKB/TrEMBL
	PS51484	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000058742	RatGTEx
SMART	IPT	UniProtKB/TrEMBL
	PbH1	UniProtKB/TrEMBL
	SM01225	UniProtKB/TrEMBL
Superfamily-SCOP	Anthrax protective antigen	UniProtKB/TrEMBL
	SSF51126	UniProtKB/TrEMBL
	SSF81296	UniProtKB/TrEMBL
UniProt	A0A0G2K2W1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Pkhd1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin	AABR07067023.1		Data merged from RGD:15012019	737654	PROVISIONAL
2021-09-02	AABR07067023.1		Pkhd1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin	Symbol and/or name change	19259462	PROVISIONAL
2021-08-09	Pkhd1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin	AABR07067023.1		Symbol and/or name change	19259462	PROVISIONAL
2019-11-08	AABR07067023.1				Symbol and Name status set to provisional	45752	PROVISIONAL
2012-06-26	Pkhd1	polycystic kidney and hepatic disease 1	Pkhd1	polycystic kidney and hepatic disease 1 homolog (human)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-04-29	Pkhd1	polycystic kidney and hepatic disease 1 homolog (human)	Pkhd1	polycystic kidney and hepatic disease 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-07	Pkhd1	polycystic kidney and hepatic disease 1	Pkhd1_predicted	polycystic kidney and hepatic disease 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Pkhd1_predicted	polycystic kidney and hepatic disease 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM