Sumo1 (small ubiquitin-like modifier 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Sumo1 (small ubiquitin-like modifier 1) Rattus norvegicus
Analyze
Symbol: Sumo1
Name: small ubiquitin-like modifier 1
RGD ID: 1306919
Description: Predicted to enable enzyme binding activity; potassium channel regulator activity; and protein tag activity. Involved in cellular response to hypoxia. Located in chromosome; dendrite; and nuclear lumen. Human ortholog(s) of this gene implicated in orofacial cleft 10. Orthologous to several human genes including SUMO1 (small ubiquitin like modifier 1); PARTICIPATES IN sumoylation pathway; RNA transport pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC301442; MGC109561; small ubiquitin-related modifier 1; small ubiquitin-related modifier-1; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae); SMT3 suppressor of mif two 3 homolog 1 (yeast); SUMO-1; ubiquitin-like 1 (sentrin)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,572,901 - 68,602,803 (-)NCBIGRCr8
mRatBN7.2961,078,790 - 61,108,697 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,077,435 - 61,108,761 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,573,528 - 69,603,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,689,507 - 74,719,450 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,007,792 - 73,037,736 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,453,428 - 66,483,614 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,453,438 - 66,483,614 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,258,853 - 66,288,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,212,538 - 58,242,760 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,359,520 - 58,389,742 (-)NCBI
Celera958,513,570 - 58,543,459 (-)NCBICelera
Cytogenetic Map9q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratautoimmune lymphoproliferative syndrome type 2B  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autoimmune lymphoproliferative syndrome type 2BClinVarPMID:11343122 more ...
Sumo1RatAutoimmune Lymphoproliferative Syndrome, Type V  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autoimmune lymphoproliferative syndrome type VClinVarPMID:11343122 more ...
Sumo1Ratcleft lip  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Cleft Lip +/- Cleft Palate and Autosomal DominantClinVar 
Sumo1Ratcommon variable immunodeficiency 1  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency more ...ClinVarPMID:11343122 more ...
Sumo1RatNeurodevelopmental Disorders  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Sumo1Ratorofacial cleft 10  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Orofacial cleft 10ClinVarPMID:25741868
Sumo1Ratprimary pulmonary hypertension  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary pulmonary hypertensionClinVarPMID:16429395 more ...
Sumo1RatPulmonary Arterial Hypertension  ISOSUMO1 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary arterial hypertensionClinVarPMID:32581362
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratcleft lip  ISOSUMO1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16990542
Sumo1Ratcleft palate  ISOSUMO1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16990542
Sumo1RatNeoplasm Invasiveness  ISOSUMO1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15048980
Sumo1Ratorofacial cleft 10  ISOSUMO1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratorofacial cleft 10  ISOSUMO1 (Homo sapiens)7240710 OMIM 

1 to 20 of 123 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Rat(1->4)-beta-D-glucan multiple interactionsISOSumo1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SUMO1 mRNACTDPMID:36331819
Sumo1Rat(R)-lipoic acid increases expressionISOSUMO1 (Homo sapiens)6480464Thioctic Acid results in increased expression of SUMO1 proteinCTDPMID:24975507
Sumo1Rat1,2-dichloroethane decreases expressionISOSumo1 (Mus musculus)6480464ethylene dichloride results in decreased expression of SUMO1 mRNACTDPMID:28189721 and PMID:28960355
Sumo1Rat1,2-dimethylhydrazine multiple interactionsISOSumo1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SUMO1 mRNACTDPMID:22206623
Sumo1Rat1,2-dimethylhydrazine decreases expressionISOSumo1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of SUMO1 mRNACTDPMID:22206623
Sumo1Rat17alpha-ethynylestradiol increases expressionISOSumo1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of SUMO1 mRNACTDPMID:17555576
Sumo1Rat17beta-estradiol decreases expressionISOSUMO1 (Homo sapiens)6480464Estradiol results in decreased expression of SUMO1 mRNACTDPMID:23019147
Sumo1Rat17beta-estradiol decreases expressionISOSumo1 (Mus musculus)6480464Estradiol results in decreased expression of SUMO1 mRNACTDPMID:39298647
Sumo1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSumo1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SUMO1 mRNACTDPMID:21570461
Sumo1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOSumo1 (Mus musculus)6480464AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SUMO1 mRNA]CTDPMID:15034205
Sumo1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOSumo1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of SUMO1 mRNACTDPMID:15034205
Sumo1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of SUMO1 mRNACTDPMID:21346803
Sumo1Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of SUMO1 mRNACTDPMID:21346803
Sumo1Rat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of SUMO1 mRNACTDPMID:19162173
Sumo1Rat4,4'-sulfonyldiphenol decreases expressionISOSumo1 (Mus musculus)6480464bisphenol S results in decreased expression of SUMO1 mRNACTDPMID:39298647
Sumo1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of SUMO1 mRNACTDPMID:30047161
Sumo1Ratacetylsalicylic acid decreases expressionISOSUMO1 (Homo sapiens)6480464Aspirin results in decreased expression of SUMO1 mRNACTDPMID:11906190
Sumo1Ratacrolein multiple interactionsISOSUMO1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SUMO1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SUMO1 mRNACTDPMID:32699268
Sumo1Ratactinomycin D multiple interactionsISOSUMO1 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of SUMO1 proteinCTDPMID:38460933
Sumo1Rataflatoxin M1 decreases expressionISOSUMO1 (Homo sapiens)6480464Aflatoxin M1 results in decreased expression of SUMO1 mRNACTDPMID:30928695

1 to 20 of 123 rows

Biological Process
1 to 20 of 33 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratcellular response to cadmium ion involved_inISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratcellular response to cadmium ion involved_inISOSUMO1 (Homo sapiens)1624291 PMID:11514557RGDPMID:11514557
Sumo1Ratcellular response to heat involved_inISOSUMO1 (Homo sapiens)1624291 PMID:11514557RGDPMID:11514557
Sumo1Ratcellular response to heat involved_inISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratcellular response to hypoxia  IEP 9587773 RGD 
Sumo1Ratnegative regulation of action potential involved_inISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratnegative regulation of action potential involved_inISOSUMO1 (Homo sapiens)1624291 PMID:19223394RGDPMID:19223394
Sumo1Ratnegative regulation of delayed rectifier potassium channel activity involved_inISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratnegative regulation of delayed rectifier potassium channel activity involved_inISOSUMO1 (Homo sapiens)1624291 PMID:19223394RGDPMID:19223394
Sumo1Ratnegative regulation of DNA-binding transcription factor activity involved_inISOSUMO1 (Homo sapiens)1624291 PMID:12072434RGDPMID:12072434
Sumo1Ratnegative regulation of DNA-templated transcription involved_inISOSUMO1 (Homo sapiens)1624291 PMID:12072434RGDPMID:12072434
Sumo1Ratnegative regulation of DNA-templated transcription acts_upstream_ofISOSUMO1 (Homo sapiens)1624291 PMID:15572661RGDPMID:15572661
Sumo1Ratnegative regulation of potassium ion transmembrane transporter activity involved_inISOSUMO1 (Homo sapiens)1624291 PMID:23169818RGDPMID:23169818
Sumo1Ratnegative regulation of protein import into nucleus involved_inISOSUMO1 (Homo sapiens)1624291 PMID:17264123RGDPMID:17264123
Sumo1Ratnegative regulation of transcription by transcription factor localization acts_upstream_ofISOSUMO1 (Homo sapiens)1624291 PMID:17264123RGDPMID:17264123
Sumo1RatPML body organization acts_upstream_of_or_withinISOSumo1 (Mus musculus)1624291MGI:3819343 PMID:19033381RGDPMID:19033381
Sumo1Ratpositive regulation of ATPase-coupled calcium transmembrane transporter activity involved_inISOSumo1 (Mus musculus)1624291 PMID:21900893RGDPMID:21900893
Sumo1Ratpositive regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inISOSUMO1 (Homo sapiens)1624291 PMID:18408734RGDPMID:18408734
Sumo1Ratpositive regulation of protein-containing complex assembly involved_inISOSUMO1 (Homo sapiens)1624291 PMID:18579533RGDPMID:18579533
Sumo1Ratprotein localization to nuclear pore acts_upstream_of_or_withinISOSumo1 (Mus musculus)1624291MGI:3819343 PMID:19033381RGDPMID:19033381
1 to 20 of 33 rows

Cellular Component
1 to 20 of 37 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Sumo1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Sumo1Ratdendrite  IDA 1642482 RGD 
Sumo1Ratfibrillar center  IDA 2301351 RGD 
Sumo1Ratglutamatergic synapse is_active_inISOSumo1 (Mus musculus)1624291 PMID:31749687RGDPMID:31749687
Sumo1Ratheterochromatin located_inIDA 9587797 RGD 
Sumo1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Sumo1Ratnuclear body located_inISOSUMO1 (Homo sapiens) and UniProtKB:P63165-11624291 RGDGO_REF:0000052
Sumo1Ratnuclear body located_inISOSumo1 (Mus musculus)1624291 PMID:18681895RGDPMID:18681895
Sumo1Ratnuclear body located_inISOSUMO1 (Homo sapiens)1624291 PMID:24651376RGDPMID:24651376
Sumo1Ratnuclear membrane located_inIEAUniProtKB-SubCell:SL-01821600115GO_REF:0000044UniProtGO_REF:0000044
Sumo1Ratnuclear membrane located_inISOSUMO1 (Homo sapiens) and UniProtKB:P63165-11624291 RGDGO_REF:0000052
Sumo1Ratnuclear speck located_inIEAUniProtKB-SubCell:SL-01861600115GO_REF:0000044UniProtGO_REF:0000044
Sumo1Ratnuclear stress granule located_inISOSUMO1 (Homo sapiens)1624291 PMID:11514557RGDPMID:11514557
Sumo1Ratnuclear stress granule located_inISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratnucleolus located_inISOSUMO1 (Homo sapiens) and UniProtKB:P63165-11624291 RGDGO_REF:0000052
Sumo1Ratnucleoplasm located_inISOSUMO1 (Homo sapiens) and UniProtKB:P63165-11624291 RGDGO_REF:0000052
Sumo1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Sumo1Ratnucleus located_inISOSumo1 (Mus musculus)1624291 PMID:15767674 and PMID:21931855RGDPMID:15767674 and PMID:21931855
Sumo1Ratnucleus is_active_inIBAFB:FBgn0264922 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 20 of 37 rows

Molecular Function
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratenzyme binding enablesISOSUMO1 (Homo sapiens)1624291UniProtKB:Q13569 and PMID:15959518RGDPMID:15959518
Sumo1Ratpotassium channel regulator activity enablesISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratpotassium channel regulator activity enablesISOSUMO1 (Homo sapiens)1624291 PMID:19223394RGDPMID:19223394
Sumo1Ratprotein binding  IPITollip (Rattus norvegicus)5508208 RGD 
Sumo1Ratprotein binding enablesISOSumo1 (Mus musculus)1624291UniProtKB:P18031 more ...RGDPMID:15767674 more ...
Sumo1Ratprotein binding enablesISOSUMO1 (Sus scrofa)1624291UniProtKB:P21530-PRO_0000038063 more ...RGDPMID:20800867 and PMID:25010283
Sumo1Ratprotein binding enablesIPIUniProtKB:P422601642482PMID:17486098IntAct 
Sumo1Ratprotein binding enablesIPIUniProtKB:P422608554830PMID:22483987IntAct 
Sumo1Ratprotein binding enablesIPIUniProtKB:P4226013432300PMID:22089239IntAct 
Sumo1Ratprotein binding enablesIPIUniProtKB:P3865613432294PMID:17646655IntAct 
Sumo1Ratprotein binding enablesISOSUMO1 (Homo sapiens)1624291UniProtKB:A0A0S2Z3N6 more ...RGDPMID:11112409 more ...
Sumo1Ratprotein tag activity enablesISOSUMO1 (Homo sapiens)1624291 PMID:23169818RGDPMID:23169818
Sumo1Ratprotein tag activity enablesIBACGD:CAL0000178394 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sumo1Ratsmall protein activating enzyme binding enablesISOSUMO1 (Homo sapiens)1624291UniProtKB:Q9UBT2 and PMID:15660128RGDPMID:15660128
Sumo1Ratubiquitin protein ligase binding enablesISSUniProtKB:P631651600115GO_REF:0000024UniProtGO_REF:0000024
Sumo1Ratubiquitin protein ligase binding enablesISOSUMO1 (Homo sapiens)1624291UniProtKB:O88846 and PMID:18408734RGDPMID:18408734
Sumo1Ratubiquitin-like protein ligase binding enablesIBAPANTHER:PTN000059492 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sumo1Ratubiquitin-specific protease binding enablesISOSUMO1 (Homo sapiens)1624291UniProtKB:Q9UHP3 and PMID:18538659RGDPMID:18538659
1 to 18 of 18 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1Ratsumoylation pathway  IDA 1642482 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sumo1RatRNA transport pathway  IEA 6907045 KEGGrno:03013

1 to 15 of 15 rows
#
Reference Title
Reference Citation
1. The giant fibrillar center: a nucleolar structure enriched in upstream binding factor (UBF) that appears in transcriptionally more active sensory ganglia neurons. Casafont I, etal., J Struct Biol. 2007 Sep;159(3):451-61. Epub 2007 May 25.
2. Tollip is a mediator of protein sumoylation. Ciarrocchi A, etal., PLoS One. 2009;4(2):e4404. Epub 2009 Feb 9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Subcellular localization of Daxx determines its opposing functions in ischemic cell death. Jung YS, etal., FEBS Lett. 2007 Mar 6;581(5):843-52. Epub 2007 Feb 2.
5. Agonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis. Konopacki FA, etal., Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19772-7. doi: 10.1073/pnas.1111575108. Epub 2011 Nov 16.
6. SUMOylation regulates kainate-receptor-mediated synaptic transmission. Martin S, etal., Nature. 2007 May 17;447(7142):321-5. Epub 2007 May 7.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. SUMO modified proteins localize to the XY body of pachytene spermatocytes. Rogers RS, etal., Chromosoma. 2004 Nov;113(5):233-43. Epub 2004 Sep 3.
14. Sumoylation in axons triggers retrograde transport of the RNA-binding protein La. van Niekerk EA, etal., Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12913-8. Epub 2007 Jul 23.
15. SUMOylation of the kainate receptor subunit GluK2 contributes to the activation of the MLK3-JNK3 pathway following kainate stimulation. Zhu QJ, etal., FEBS Lett. 2012 May 7;586(9):1259-64. doi: 10.1016/j.febslet.2012.03.048. Epub 2012 Mar 31.
1 to 15 of 15 rows
PMID:9412458   PMID:9885291   PMID:11514557   PMID:11889051   PMID:12072434   PMID:12477932   PMID:14752048   PMID:15023536   PMID:15489334   PMID:15572661   PMID:15637059   PMID:15660128  
PMID:15767674   PMID:15950612   PMID:15959518   PMID:16144832   PMID:16626738   PMID:16735515   PMID:16791210   PMID:16955485   PMID:16990542   PMID:17000718   PMID:17053029   PMID:17081985  
PMID:17081986   PMID:17696781   PMID:18408734   PMID:18538659   PMID:18571432   PMID:18579533   PMID:18644859   PMID:18681895   PMID:19033381   PMID:19200349   PMID:19223394   PMID:19744555  
PMID:19819240   PMID:20209145   PMID:20725866   PMID:21070824   PMID:21454665   PMID:21518833   PMID:21900893   PMID:21931855   PMID:21965678   PMID:21968017   PMID:22082260   PMID:22406621  
PMID:22658674   PMID:23639777   PMID:24651376   PMID:25220405   PMID:25236484   PMID:25378699   PMID:25634095   PMID:25976847   PMID:26979866   PMID:28553222   PMID:28902364   PMID:31642335  
PMID:35002525  



Sumo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,572,901 - 68,602,803 (-)NCBIGRCr8
mRatBN7.2961,078,790 - 61,108,697 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,077,435 - 61,108,761 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,573,528 - 69,603,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,689,507 - 74,719,450 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,007,792 - 73,037,736 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,453,428 - 66,483,614 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,453,438 - 66,483,614 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,258,853 - 66,288,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,212,538 - 58,242,760 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,359,520 - 58,389,742 (-)NCBI
Celera958,513,570 - 58,543,459 (-)NCBICelera
Cytogenetic Map9q31NCBI
SUMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,206,171 - 202,238,597 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,206,182 - 202,238,599 (-)EnsemblGRCh38hg38GRCh38
GRCh372203,070,894 - 203,103,320 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362202,779,148 - 202,811,567 (-)NCBINCBI36Build 36hg18NCBI36
Build 342202,896,408 - 202,928,828NCBI
Celera2196,822,670 - 196,855,115 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2194,919,783 - 194,951,410 (-)NCBIHuRef
CHM1_12203,077,457 - 203,109,867 (-)NCBICHM1_1
T2T-CHM13v2.02202,687,204 - 202,719,634 (-)NCBIT2T-CHM13v2.0
Sumo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,678,593 - 59,709,993 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,625,717 - 59,709,993 (-)EnsemblGRCm39 Ensembl
GRCm38159,639,434 - 59,670,834 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,586,558 - 59,670,834 (-)EnsemblGRCm38mm10GRCm38
MGSCv37159,696,278 - 59,727,678 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36159,583,983 - 59,615,355 (-)NCBIMGSCv36mm8
Celera160,154,082 - 60,185,562 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.32NCBI
Sumo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,538,480 - 12,565,803 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545712,538,974 - 12,565,803 (+)NCBIChiLan1.0ChiLan1.0
SUMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213104,831,064 - 104,863,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B104,846,063 - 104,878,299 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B89,461,773 - 89,493,879 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B207,613,649 - 207,645,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B207,613,654 - 207,645,590 (-)Ensemblpanpan1.1panPan2
SUMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,199,937 - 11,229,743 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,200,590 - 11,229,754 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,083,987 - 12,113,143 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,136,626 - 11,165,785 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,133,840 - 11,166,196 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,087,432 - 11,116,739 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,065,890 - 11,095,045 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,059,162 - 11,088,313 (-)NCBIUU_Cfam_GSD_1.0
Sumo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,432,685 - 159,443,682 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,399,050 - 1,429,205 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,402,977 - 1,413,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15105,818,858 - 105,850,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115105,820,237 - 105,850,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,249,291 - 117,249,369 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SUMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11087,917,324 - 87,957,152 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040111,440,837 - 111,472,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sumo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476514,205,051 - 14,229,864 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476514,205,071 - 14,229,864 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Sumo1
120 total Variants

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:97
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000022047
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat

1 to 10 of 29 rows
BE117566  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,095,681 - 61,095,831 (+)MAPPERmRatBN7.2
Rnor_6.0966,470,604 - 66,470,753NCBIRnor6.0
Rnor_5.0966,275,093 - 66,275,242UniSTSRnor5.0
RGSC_v3.4958,229,750 - 58,229,899UniSTSRGSC3.4
Celera958,530,447 - 58,530,596UniSTS
RH 3.4 Map9515.8UniSTS
Cytogenetic Map9q31UniSTS
RH136616  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24155,619,936 - 155,620,127 (+)MAPPERmRatBN7.2
Rnor_6.04155,206,093 - 155,206,283NCBIRnor6.0
Rnor_5.04222,231,621 - 222,231,811UniSTSRnor5.0
RGSC_v3.44158,849,978 - 158,850,168UniSTSRGSC3.4
Celera4144,441,045 - 144,441,235UniSTS
Cytogenetic Map9q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000022047   ⟹   ENSRNOP00000022048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,078,797 - 61,108,761 (-)Ensembl
Rnor_6.0 Ensembl966,453,438 - 66,483,614 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108699   ⟹   ENSRNOP00000087606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,077,435 - 61,095,467 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109220   ⟹   ENSRNOP00000092576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,078,818 - 61,108,500 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109290   ⟹   ENSRNOP00000080272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,077,435 - 61,108,725 (-)Ensembl
RefSeq Acc Id: NM_001009672   ⟹   NP_001009672
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,572,901 - 68,602,803 (-)NCBI
mRatBN7.2961,078,790 - 61,108,697 (-)NCBI
Rnor_6.0966,453,428 - 66,483,614 (-)NCBI
Rnor_5.0966,258,853 - 66,288,103 (-)NCBI
RGSC_v3.4958,212,538 - 58,242,760 (-)RGD
Celera958,513,570 - 58,543,459 (-)RGD
Sequence:
Protein RefSeqs NP_001009672 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88322 (Get FASTA)   NCBI Sequence Viewer  
  EDL98949 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022048
GenBank Protein Q5I0H3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009672   ⟸   NM_001009672
- UniProtKB: Q5I0H3 (UniProtKB/Swiss-Prot),   A6IPB1 (UniProtKB/TrEMBL),   A0A8I6A3G5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022048   ⟸   ENSRNOT00000022047
Ensembl Acc Id: ENSRNOP00000092576   ⟸   ENSRNOT00000109220
Ensembl Acc Id: ENSRNOP00000087606   ⟸   ENSRNOT00000108699
Ensembl Acc Id: ENSRNOP00000080272   ⟸   ENSRNOT00000109290
Ubiquitin-like

Name Modeler Protein Id AA Range Protein Structure
AF-Q5I0H3-F1-model_v2 AlphaFold Q5I0H3 1-101 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696702
Promoter ID:EPDNEW_R7227
Type:initiation region
Name:Sumo1_1
Description:small ubiquitin-like modifier 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0966,483,686 - 66,483,746EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-27405 BioCyc
Ensembl Genes ENSRNOG00000016133 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022047 ENTREZGENE
Gene3D-CATH Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7325996 IMAGE-MGC_LOAD
InterPro Rad60/SUMO-like_dom UniProtKB/Swiss-Prot
  SUMO1_Ubl UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
  Ubiquitin_dom UniProtKB/Swiss-Prot
KEGG Report rno:301442 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109561 IMAGE-MGC_LOAD
NCBI Gene 301442 ENTREZGENE
PANTHER SMALL UBIQUITIN-RELATED MODIFIER UniProtKB/Swiss-Prot
Pfam Rad60-SLD UniProtKB/Swiss-Prot
PhenoGen Sumo1 PhenoGen
PROSITE UBIQUITIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016133 RatGTEx
SMART UBQ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPY9_RAT UniProtKB/TrEMBL
  A0A8I6A3G5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AI63_RAT UniProtKB/TrEMBL
  A0A8L2UJM8_RAT UniProtKB/TrEMBL
  A6IPB1 ENTREZGENE, UniProtKB/TrEMBL
  Q5I0H3 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-14 Sumo1  small ubiquitin-like modifier 1  Sumo1  SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Sumo1  SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)  Sumo1  SMT3 suppressor of mif two 3 homolog 1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sumo1  SMT3 suppressor of mif two 3 homolog 1 (yeast)  Sumo1_predicted  SMT3 suppressor of mif two 3 homolog 1 (yeast) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sumo1_predicted  SMT3 suppressor of mif two 3 homolog 1 (yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED