SUMO1 (small ubiquitin like modifier 1) - Rat Genome Database

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Gene: SUMO1 (small ubiquitin like modifier 1) Canis lupus familiaris
Analyze
Symbol: SUMO1
Name: small ubiquitin like modifier 1
RGD ID: 12347260
Description: ENCODES a protein that exhibits enzyme binding (ortholog); potassium channel regulator activity (ortholog); small protein activating enzyme binding (ortholog); INVOLVED IN cellular response to cadmium ion (ortholog); cellular response to heat (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN sumoylation pathway; ASSOCIATED WITH autoimmune lymphoproliferative syndrome type 2B (ortholog); Autoimmune Lymphoproliferative Syndrome, Type V (ortholog); cleft lip (ortholog); FOUND IN dendrite (ortholog); fibrillar center (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: small ubiquitin-like modifier 1; small ubiquitin-related modifier 1; SMT3 suppressor of mif two 3 homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,199,937 - 11,229,743 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,200,590 - 11,229,754 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,083,987 - 12,113,143 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,136,626 - 11,165,785 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,133,840 - 11,166,196 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,087,432 - 11,116,739 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,065,890 - 11,095,045 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,059,162 - 11,088,313 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SUMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,199,937 - 11,229,743 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,200,590 - 11,229,754 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,083,987 - 12,113,143 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,136,626 - 11,165,785 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,133,840 - 11,166,196 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,087,432 - 11,116,739 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,065,890 - 11,095,045 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,059,162 - 11,088,313 (-)NCBIUU_Cfam_GSD_1.0
SUMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,206,171 - 202,238,597 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,206,182 - 202,238,599 (-)EnsemblGRCh38hg38GRCh38
GRCh372203,070,894 - 203,103,320 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362202,779,148 - 202,811,567 (-)NCBINCBI36Build 36hg18NCBI36
Build 342202,896,408 - 202,928,828NCBI
Celera2196,822,670 - 196,855,115 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2194,919,783 - 194,951,410 (-)NCBIHuRef
CHM1_12203,077,457 - 203,109,867 (-)NCBICHM1_1
T2T-CHM13v2.02202,687,204 - 202,719,634 (-)NCBIT2T-CHM13v2.0
Sumo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,678,593 - 59,709,993 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,625,717 - 59,709,993 (-)EnsemblGRCm39 Ensembl
GRCm38159,639,434 - 59,670,834 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,586,558 - 59,670,834 (-)EnsemblGRCm38mm10GRCm38
MGSCv37159,696,278 - 59,727,678 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36159,583,983 - 59,615,355 (-)NCBIMGSCv36mm8
Celera160,154,082 - 60,185,562 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.32NCBI
Sumo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,572,901 - 68,602,803 (-)NCBIGRCr8
mRatBN7.2961,078,790 - 61,108,697 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,077,435 - 61,108,761 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,573,528 - 69,603,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,689,507 - 74,719,450 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,007,792 - 73,037,736 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,453,428 - 66,483,614 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,453,438 - 66,483,614 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,258,853 - 66,288,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,212,538 - 58,242,760 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,359,520 - 58,389,742 (-)NCBI
Celera958,513,570 - 58,543,459 (-)NCBICelera
Cytogenetic Map9q31NCBI
Sumo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,538,480 - 12,565,803 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545712,538,974 - 12,565,803 (+)NCBIChiLan1.0ChiLan1.0
SUMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213104,831,064 - 104,863,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B104,846,063 - 104,878,299 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B89,461,773 - 89,493,879 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B207,613,649 - 207,645,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B207,613,654 - 207,645,590 (-)Ensemblpanpan1.1panPan2
Sumo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,432,685 - 159,443,682 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,399,050 - 1,429,205 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,402,977 - 1,413,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15105,818,858 - 105,850,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115105,820,237 - 105,850,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,249,291 - 117,249,369 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SUMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11087,917,324 - 87,957,152 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040111,440,837 - 111,472,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sumo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476514,205,051 - 14,229,864 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476514,205,071 - 14,229,864 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SUMO1
345 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000019737   ⟹   ENSCAFP00000018307
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3711,200,590 - 11,229,743 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000066252   ⟹   ENSCAFP00000052182
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3711,209,377 - 11,225,791 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074317   ⟹   ENSCAFP00000047284
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3711,200,590 - 11,229,645 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000075569   ⟹   ENSCAFP00000052963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3711,201,027 - 11,229,754 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845027217   ⟹   ENSCAFP00845021411
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3711,133,840 - 11,165,687 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845027253   ⟹   ENSCAFP00845021442
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3711,136,295 - 11,166,196 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845027273   ⟹   ENSCAFP00845021461
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3711,137,063 - 11,165,799 (-)Ensembl
RefSeq Acc Id: NM_001252263   ⟹   NP_001239192
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13711,200,590 - 11,229,743 (-)NCBI
Dog10K_Boxer_Tasha3712,083,987 - 12,113,143 (-)NCBI
ROS_Cfam_1.03711,136,626 - 11,165,785 (-)NCBI
UMICH_Zoey_3.13711,087,432 - 11,116,739 (-)NCBI
UNSW_CanFamBas_1.03711,065,890 - 11,095,045 (-)NCBI
UU_Cfam_GSD_1.03711,059,162 - 11,088,313 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001239192   ⟸   NM_001252263
- UniProtKB: A0A8C0RNS4 (UniProtKB/TrEMBL),   A0A8P0PJL9 (UniProtKB/TrEMBL),   A0A8C0QU37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000047284   ⟸   ENSCAFT00000074317
RefSeq Acc Id: ENSCAFP00000018307   ⟸   ENSCAFT00000019737
RefSeq Acc Id: ENSCAFP00000052182   ⟸   ENSCAFT00000066252
RefSeq Acc Id: ENSCAFP00000052963   ⟸   ENSCAFT00000075569
RefSeq Acc Id: ENSCAFP00845021442   ⟸   ENSCAFT00845027253
RefSeq Acc Id: ENSCAFP00845021411   ⟸   ENSCAFT00845027217
RefSeq Acc Id: ENSCAFP00845021461   ⟸   ENSCAFT00845027273
Protein Domains
Rad60/SUMO-like   Ubiquitin-like

Promoters
RGD ID:13689120
Promoter ID:EPDNEW_C7188
Type:initiation region
Name:SUMO1_1
Description:small ubiquitin-like modifier 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13711,229,757 - 11,229,817EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012431 Ensembl
  ENSCAFG00000053787 UniProtKB/TrEMBL
  ENSCAFG00030019311 UniProtKB/TrEMBL
  ENSCAFG00040024530 UniProtKB/TrEMBL
  ENSCAFG00845015246 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000075569.2 UniProtKB/TrEMBL
  ENSCAFT00000095095.1 UniProtKB/TrEMBL
  ENSCAFT00000096885.1 UniProtKB/TrEMBL
  ENSCAFT00030035618.1 UniProtKB/TrEMBL
  ENSCAFT00030035669.1 UniProtKB/TrEMBL
  ENSCAFT00030035711.1 UniProtKB/TrEMBL
  ENSCAFT00040045697.1 UniProtKB/TrEMBL
  ENSCAFT00040045713.1 UniProtKB/TrEMBL
  ENSCAFT00040045731.1 UniProtKB/TrEMBL
  ENSCAFT00845027217.1 UniProtKB/TrEMBL
  ENSCAFT00845027253.1 UniProtKB/TrEMBL
  ENSCAFT00845027273.1 UniProtKB/TrEMBL
InterPro Rad60/SUMO-like_dom UniProtKB/TrEMBL
  SUMO1_Ubl UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report cfa:478874 UniProtKB/TrEMBL
NCBI Gene SUMO1 ENTREZGENE
PANTHER SMALL UBIQUITIN-RELATED MODIFIER UniProtKB/TrEMBL
  SMALL UBIQUITIN-RELATED MODIFIER 1 UniProtKB/TrEMBL
Pfam Rad60-SLD UniProtKB/TrEMBL
PROSITE UBIQUITIN_2 UniProtKB/TrEMBL
SMART UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A8C0NSF2_CANLF UniProtKB/TrEMBL
  A0A8C0QU37 ENTREZGENE
  A0A8C0RNS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TQY8_CANLF UniProtKB/TrEMBL
  A0A8I3NW98_CANLF UniProtKB/TrEMBL
  A0A8I3NZS0_CANLF UniProtKB/TrEMBL
  A0A8I3P0M5_CANLF UniProtKB/TrEMBL
  A0A8P0PJL9 ENTREZGENE
UniProt Secondary A0A8P0PJL9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-26 SUMO1  small ubiquitin like modifier 1    small ubiquitin-like modifier 1  Symbol and/or name change 5135510 APPROVED