Il17ra (interleukin 17 receptor A) - Rat Genome Database

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Gene: Il17ra (interleukin 17 receptor A) Rattus norvegicus
Analyze
Symbol: Il17ra
Name: interleukin 17 receptor A
RGD ID: 1306559
Description: Predicted to enable interleukin-17 receptor activity and signaling receptor binding activity. Involved in cellular response to cytokine stimulus. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 51. Orthologous to human IL17RA (interleukin 17 receptor A); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Il17r; interleukin 17 receptor; interleukin-17 receptor A; LOC312679
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84155,339,742 - 155,362,382 (+)NCBIGRCr8
mRatBN7.24153,667,534 - 153,690,174 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4153,667,534 - 153,690,174 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4159,942,994 - 159,965,630 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04155,726,725 - 155,749,362 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04154,350,081 - 154,372,717 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04152,995,865 - 153,018,394 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4152,995,865 - 153,018,394 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,083,472 - 220,106,001 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44156,838,353 - 156,862,345 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14157,083,050 - 157,107,186 (+)NCBI
Celera4142,518,868 - 142,541,353 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatExperimental Liver Cirrhosis treatmentIEP 151665755 RGD 
Il17raRatextrinsic allergic alveolitis  ISOIl17ra (Mus musculus)5144217 RGD 
Il17raRatHuman Influenza  ISOIl17ra (Mus musculus)4889102 RGD 
Il17raRatpulmonary emphysema  ISOIl17ra (Mus musculus)5144212 RGD 
Il17raRatviral pneumonia  ISOIL17RA (Homo sapiens)9068941mRNA:decreased expression:bronchoalveolar lavage (human)RGDPMID:32407669 and REF_RGD_ID:30296672
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatchronic mucocutaneous candidiasis  ISOIL17RA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16670328 more ...
Il17raRatimmunodeficiency 51  ISOIL17RA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
Il17raRatNeurodevelopmental Disorders  ISOIL17RA (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Il17raRatPolyarteritis Nodosa, Childhood-Onset  ISOIL17RA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24552284 more ...
Il17raRatpsoriasis  ISOIL17RA (Homo sapiens)8554872ClinVar Annotator: match by term: PsoriasisClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatbrain ischemia  ISOIL17RA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15829914
Il17raRatInflammation  ISOIL17RA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:29724254
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatimmunodeficiency 51  ISOIL17RA (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRat(+)-catechin multiple interactionsISOIL17RA (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of IL17RA mRNACTDPMID:24763279
Il17raRat(1->4)-beta-D-glucan multiple interactionsISOIl17ra (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IL17RA mRNACTDPMID:36331819
Il17raRat1,2-dimethylhydrazine increases expressionISOIl17ra (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of IL17RA mRNACTDPMID:22206623
Il17raRat17alpha-ethynylestradiol increases expressionISOIl17ra (Mus musculus)6480464Ethinyl Estradiol results in increased expression of IL17RA mRNACTDPMID:12072388 and PMID:36329302
Il17raRat17beta-estradiol affects expressionISOIl17ra (Mus musculus)6480464Estradiol affects the expression of IL17RA mRNACTDPMID:15598610
Il17raRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of IL17RA mRNACTDPMID:22298810
Il17raRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of IL17RA mRNACTDPMID:34747641
Il17raRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOIl17ra (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of IL17RA mRNACTDPMID:25975270
Il17raRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of IL17RA mRNACTDPMID:21215274
Il17raRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of IL17R mRNACTDPMID:21346803
Il17raRat2-hydroxypropanoic acid decreases expressionISOIL17RA (Homo sapiens)6480464Lactic Acid results in decreased expression of IL17RA mRNACTDPMID:30851411
Il17raRat4,4'-sulfonyldiphenol decreases expressionISOIl17ra (Mus musculus)6480464bisphenol S results in decreased expression of IL17RA mRNACTDPMID:39298647
Il17raRat4,4'-sulfonyldiphenol increases methylationISOIL17RA (Homo sapiens)6480464bisphenol S results in increased methylation of IL17RA geneCTDPMID:31601247
Il17raRat4-hydroxyphenyl retinamide increases expressionISOIl17ra (Mus musculus)6480464Fenretinide results in increased expression of IL17RA mRNACTDPMID:28973697
Il17raRat7,12-dimethyltetraphene multiple interactionsISOIl17ra (Mus musculus)6480464IL17RA results in increased susceptibility to [9 more ...CTDPMID:22359662
Il17raRatacrylamide increases expressionISOIL17RA (Homo sapiens)6480464Acrylamide results in increased expression of IL17RA mRNACTDPMID:32763439
Il17raRataflatoxin B1 increases methylationISOIL17RA (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of IL17RA geneCTDPMID:27153756
Il17raRataldehydo-D-glucose increases expressionISOIl17ra (Mus musculus)6480464Glucose results in increased expression of IL17RA mRNACTDPMID:18310510
Il17raRatall-trans-retinoic acid decreases expressionISOIL17RA (Homo sapiens)6480464Tretinoin results in decreased expression of IL17RA mRNACTDPMID:33167477
Il17raRatantirheumatic drug decreases expressionISOIL17RA (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of IL17RA mRNACTDPMID:24449571

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Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatcellular response to cytokine stimulus  IDA 5144218IL-1β and /IFN-γRGD 
Il17raRatdefense response to fungus involved_inISOIl17ra (Mus musculus)1624291 PMID:20554964RGDPMID:20554964
Il17raRatfibroblast activation involved_inISOIL17RA (Homo sapiens)1624291 PMID:21145111RGDPMID:21145111
Il17raRatgranulocyte chemotaxis involved_inISOIl17ra (Mus musculus)1624291 PMID:20554964RGDPMID:20554964
Il17raRatinterleukin-17-mediated signaling pathway involved_inISOIL17RA (Homo sapiens)1624291 PMID:21350122 and PMID:33723527RGDPMID:21350122 and PMID:33723527
Il17raRatinterleukin-17-mediated signaling pathway involved_inISOIl17ra (Mus musculus)1624291 PMID:19825828 more ...RGDPMID:19825828 more ...
Il17raRatinterleukin-17A-mediated signaling pathway involved_inISOIL17RA (Homo sapiens)1624291 PMID:9367539RGDPMID:9367539
Il17raRatpositive regulation of chemokine (C-X-C motif) ligand 1 production involved_inISOIL17RA (Homo sapiens)1624291 PMID:21350122RGDPMID:21350122
Il17raRatpositive regulation of cytokine production involved in inflammatory response involved_inISOIL17RA (Homo sapiens)1624291 PMID:33723527RGDPMID:33723527
Il17raRatpositive regulation of cytokine production involved in inflammatory response involved_inISOIl17ra (Mus musculus)1624291 PMID:33723527RGDPMID:33723527
Il17raRatpositive regulation of cytokine production involved in inflammatory response acts_upstream_of_or_withinISOIl17ra (Mus musculus)1624291MGI:107364 more ...RGDPMID:16785495
Il17raRatpositive regulation of inflammatory response involved_inISOIl17ra (Mus musculus)1624291 PMID:33723527RGDPMID:33723527
Il17raRatpositive regulation of inflammatory response acts_upstream_of_or_withinISOIl17ra (Mus musculus)1624291MGI:2450882 PMID:18768888RGDPMID:18768888
Il17raRatpositive regulation of inflammatory response involved_inISOIL17RA (Homo sapiens)1624291 PMID:33723527RGDPMID:33723527
Il17raRatpositive regulation of interleukin-13 production acts_upstream_of_or_withinISOIl17ra (Mus musculus)1624291MGI:2450882 PMID:18768888RGDPMID:18768888
Il17raRatpositive regulation of interleukin-23 production involved_inISOIL17RA (Homo sapiens)1624291 PMID:21145111RGDPMID:21145111
Il17raRatpositive regulation of interleukin-5 production acts_upstream_of_or_withinISOIl17ra (Mus musculus)1624291MGI:2450882 PMID:18768888RGDPMID:18768888
Il17raRatpositive regulation of interleukin-6 production involved_inISOIL17RA (Homo sapiens)1624291 PMID:21350122RGDPMID:21350122
Il17raRatprotein catabolic process involved_inISOIl17ra (Mus musculus)1624291 PMID:28561022RGDPMID:28561022
Il17raRatresponse to virus involved_inISOIl17ra (Mus musculus)1624291 PMID:33723527RGDPMID:33723527
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Il17raRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Il17raRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Il17raRatplasma membrane located_inISOIl17ra (Mus musculus)1624291 PMID:17911633RGDPMID:17911633

Molecular Function

  

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il17raRatcytokine mediated signaling pathway  IEA 6907045 KEGGrno:04060

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#
Reference Title
Reference Citation
1. Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated {beta}-Cell Death. Arif S, etal., Diabetes. 2011 Aug;60(8):2112-9. Epub 2011 Jun 9.
2. IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. Chen K, etal., PLoS One. 2011;6(5):e20333. Epub 2011 May 27.
3. Critical role of IL-17RA in immunopathology of influenza infection. Crowe CR, etal., J Immunol. 2009 Oct 15;183(8):5301-10. Epub 2009 Sep 25.
4. Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl4-induced rat liver fibrosis. Farouk S, etal., PLoS One. 2018 Oct 22;13(10):e0206130. doi: 10.1371/journal.pone.0206130. eCollection 2018.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis. Simonian PL, etal., J Immunol. 2009 May 15;182(10):6540-9.
1 to 13 of 13 rows
PMID:16785495   PMID:17827167   PMID:17911633   PMID:18768888   PMID:20554964   PMID:21145111   PMID:22851861   PMID:28898718  



Il17ra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84155,339,742 - 155,362,382 (+)NCBIGRCr8
mRatBN7.24153,667,534 - 153,690,174 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4153,667,534 - 153,690,174 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4159,942,994 - 159,965,630 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04155,726,725 - 155,749,362 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04154,350,081 - 154,372,717 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04152,995,865 - 153,018,394 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4152,995,865 - 153,018,394 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,083,472 - 220,106,001 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44156,838,353 - 156,862,345 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14157,083,050 - 157,107,186 (+)NCBI
Celera4142,518,868 - 142,541,353 (+)NCBICelera
Cytogenetic Map4q42NCBI
IL17RA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382217,085,000 - 17,115,693 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2217,084,954 - 17,115,693 (+)EnsemblGRCh38hg38GRCh38
GRCh372217,565,890 - 17,596,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362215,945,849 - 15,971,405 (+)NCBINCBI36Build 36hg18NCBI36
Build 342215,940,411 - 15,965,941NCBI
Celera221,188,127 - 1,213,694 (+)NCBICelera
Cytogenetic Map22q11.1NCBI
HuRef221,385,786 - 1,416,555 (+)NCBIHuRef
CHM1_12217,570,853 - 17,601,396 (+)NCBICHM1_1
T2T-CHM13v2.02217,761,784 - 17,792,571 (+)NCBIT2T-CHM13v2.0
Il17ra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396120,440,143 - 120,460,692 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6120,440,208 - 120,464,520 (+)EnsemblGRCm39 Ensembl
GRCm386120,463,181 - 120,483,731 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6120,463,247 - 120,487,559 (+)EnsemblGRCm38mm10GRCm38
MGSCv376120,413,215 - 120,433,745 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366120,428,854 - 120,448,651 (+)NCBIMGSCv36mm8
Celera6122,300,019 - 122,320,559 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map656.95NCBI
Il17ra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554545,230,522 - 5,254,394 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554545,230,384 - 5,252,769 (+)NCBIChiLan1.0ChiLan1.0
IL17RA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22327,397,454 - 27,430,661 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12229,947,499 - 29,981,308 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v022511,091 - 541,504 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12215,950,069 - 15,974,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2215,950,463 - 15,974,865 (+)Ensemblpanpan1.1panPan2
IL17RA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12744,798,960 - 44,812,287 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2744,791,066 - 44,811,064 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha271,866,105 - 1,888,771 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02745,159,783 - 45,182,452 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12745,089,350 - 45,111,971 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02745,061,199 - 45,083,837 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0271,223,566 - 1,246,226 (-)NCBIUU_Cfam_GSD_1.0
Il17ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945110,779,728 - 110,802,955 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936807143,165 - 165,820 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL17RA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl569,461,290 - 69,480,112 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1569,461,280 - 69,480,343 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Il17ra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473510,138,418 - 10,164,198 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473510,139,787 - 10,164,074 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Il17ra
90 total Variants

Predicted Target Of
Summary Value
Count of predictions:137
Count of miRNA genes:110
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000014885
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000014885   ⟹   ENSRNOP00000014885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4153,667,534 - 153,690,174 (+)Ensembl
Rnor_6.0 Ensembl4152,995,865 - 153,018,394 (+)Ensembl
RefSeq Acc Id: NM_001107883   ⟹   NP_001101353
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84155,339,742 - 155,362,382 (+)NCBI
mRatBN7.24153,667,534 - 153,690,174 (+)NCBI
Rnor_6.04152,995,865 - 153,018,394 (+)NCBI
Rnor_5.04220,083,472 - 220,106,001 (+)NCBI
RGSC_v3.44156,838,353 - 156,862,345 (+)RGD
Celera4142,518,868 - 142,541,353 (+)RGD
Sequence:
Protein RefSeqs NP_001101353 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM02034 (Get FASTA)   NCBI Sequence Viewer  
  EDM02035 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014885
  ENSRNOP00000014885.6
RefSeq Acc Id: NP_001101353   ⟸   NM_001107883
- UniProtKB: D4A740 (UniProtKB/TrEMBL),   A6ILA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014885   ⟸   ENSRNOT00000014885
SEFIR

Name Modeler Protein Id AA Range Protein Structure
AF-D4A740-F1-model_v2 AlphaFold D4A740 1-868 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693356
Promoter ID:EPDNEW_R3880
Type:initiation region
Name:Il17ra_1
Description:interleukin 17 receptor A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04152,995,882 - 152,995,942EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-43199 BioCyc
Ensembl Genes ENSRNOG00000011153 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014885 ENTREZGENE
  ENSRNOT00000014885.7 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2150 UniProtKB/TrEMBL
  2.60.40.2160 UniProtKB/TrEMBL
  3.40.50.11530 UniProtKB/TrEMBL
InterPro IL-17_rcpt-like UniProtKB/TrEMBL
  IL17R_fnIII_D1 UniProtKB/TrEMBL
  IL17RA/B_FnIII-like_1_sf UniProtKB/TrEMBL
  IL17RA/B_FnIII-like_2_sf UniProtKB/TrEMBL
  SEFIR UniProtKB/TrEMBL
KEGG Report rno:312679 UniProtKB/TrEMBL
NCBI Gene 312679 ENTREZGENE
PANTHER INTERLEUKIN-17 RECEPTOR A UniProtKB/TrEMBL
  PTHR15583 UniProtKB/TrEMBL
Pfam IL17R_fnIII_D1 UniProtKB/TrEMBL
  IL17R_fnIII_D2 UniProtKB/TrEMBL
  SEFIR UniProtKB/TrEMBL
PhenoGen Il17ra PhenoGen
PROSITE SEFIR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011153 RatGTEx
UniProt A6ILA4 ENTREZGENE, UniProtKB/TrEMBL
  D4A740 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Il17ra  interleukin 17 receptor A  Il17r_predicted  interleukin 17 receptor (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Il17r_predicted  interleukin 17 receptor (predicted)      Symbol and Name status set to approved 70820 APPROVED