Nelfa (negative elongation factor complex member A) - Rat Genome Database

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Gene: Nelfa (negative elongation factor complex member A) Rattus norvegicus
Analyze
Symbol: Nelfa
Name: negative elongation factor complex member A
RGD ID: 1305556
Description: Enables chromatin binding activity. Involved in positive regulation of protein modification process and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nuclear body. Predicted to be part of NELF complex. Orthologous to human NELFA (negative elongation factor complex member A); PARTICIPATES IN RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC305455; MGC95174; negative elongation factor A; Whsc2; Wolf-Hirschhorn syndrome candidate 2; Wolf-Hirschhorn syndrome candidate 2 (human)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,033,470 - 81,057,546 (+)NCBIGRCr8
mRatBN7.21476,808,920 - 76,832,998 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1476,808,870 - 76,832,994 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,260,792 - 81,284,853 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01482,501,435 - 82,525,496 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01478,946,688 - 78,970,749 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,093,837 - 82,117,913 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,093,837 - 82,117,906 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01482,778,077 - 82,802,153 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41482,502,840 - 82,526,916 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11482,505,230 - 82,529,304 (+)NCBI
Celera1475,732,469 - 75,756,545 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NelfaRatcherubism  ISONELFA (Homo sapiens)8554872ClinVar Annotator: match by term: Fibrous dysplasia of jawClinVarPMID:28492532

1 to 20 of 68 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NelfaRat17alpha-ethynylestradiol increases expressionISONelfa (Mus musculus)6480464Ethinyl Estradiol results in increased expression of NELFA mRNACTDPMID:17942748
NelfaRat17alpha-ethynylestradiol multiple interactionsISONelfa (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NELFA mRNACTDPMID:17942748
NelfaRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONelfa (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NELFA mRNACTDPMID:17942748
NelfaRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NELFA mRNACTDPMID:33387578
NelfaRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONelfa (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NELFA mRNACTDPMID:21570461
NelfaRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of NELFA mRNACTDPMID:21346803
NelfaRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of NELFA mRNACTDPMID:21346803
NelfaRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISONELFA (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NELFA mRNACTDPMID:28628672
NelfaRat4,4'-sulfonyldiphenol increases expressionISONelfa (Mus musculus)6480464bisphenol S results in increased expression of NELFA mRNACTDPMID:39298647
NelfaRat5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole multiple interactionsISONelfa (Mus musculus)6480464Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]] more ...CTDPMID:23589332
NelfaRat5,6-dichlorobenzimidazole riboside multiple interactionsISONelfa (Mus musculus)6480464Dichlororibofuranosylbenzimidazole inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]] more ...CTDPMID:23589332
NelfaRatacrolein multiple interactionsISONELFA (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NELFA mRNA more ...CTDPMID:32699268 and PMID:32845096
NelfaRataflatoxin B1 increases methylationISONELFA (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of NELFA intronCTDPMID:30157460
NelfaRatAflatoxin B2 alpha decreases methylationISONELFA (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of NELFA intronCTDPMID:30157460
NelfaRatalpha-pinene multiple interactionsISONELFA (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NELFA mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NELFA mRNACTDPMID:32699268
NelfaRatalvocidib multiple interactionsISONelfa (Mus musculus)6480464alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]] more ...CTDPMID:23589332
NelfaRatantirheumatic drug increases expressionISONELFA (Homo sapiens)6480464Antirheumatic Agents results in increased expression of NELFA mRNACTDPMID:24449571
NelfaRatarsane affects methylationISONELFA (Homo sapiens)6480464Arsenic affects the methylation of NELFA geneCTDPMID:25304211
NelfaRatarsenic atom affects methylationISONELFA (Homo sapiens)6480464Arsenic affects the methylation of NELFA geneCTDPMID:25304211
NelfaRatbenzo[a]pyrene affects methylationISONELFA (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of NELFA intronCTDPMID:30157460

1 to 20 of 68 rows

Biological Process

  

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NelfaRatcytosol located_inIEAUniProtKB:Q9H3P2 and ensembl:ENSP000003723351600115GO_REF:0000107EnsemblGO_REF:0000107
NelfaRatcytosol located_inISONELFA (Homo sapiens) and UniProtKB:Q9H3P2-11624291 RGDGO_REF:0000052
NelfaRatNELF complex part_ofISONELFA (Homo sapiens)1624291 PMID:12612062RGDPMID:12612062
NelfaRatNELF complex part_ofIBAFB:FBgn0038872 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NelfaRatNELF complex part_ofIEAUniProtKB:Q9H3P2 and ensembl:ENSP000003723351600115GO_REF:0000107EnsemblGO_REF:0000107
NelfaRatnuclear body located_inIEAUniProtKB:Q9H3P2 and ensembl:ENSP000003723351600115GO_REF:0000107EnsemblGO_REF:0000107
NelfaRatnuclear body located_inISONELFA (Homo sapiens) and UniProtKB:Q9H3P2-11624291 RGDGO_REF:0000052
NelfaRatnucleoplasm located_inISONELFA (Homo sapiens) and UniProtKB:Q9H3P2-11624291 RGDGO_REF:0000052
NelfaRatnucleoplasm located_inIEAUniProtKB:Q9H3P2 and ensembl:ENSP000003723351600115GO_REF:0000107EnsemblGO_REF:0000107
NelfaRatnucleus located_inISONelfa (Mus musculus)1624291 PMID:19796622RGDPMID:19796622
NelfaRatnucleus located_inIEAUniProtKB:Q9H3P2 and ensembl:ENSP000003723351600115GO_REF:0000107EnsemblGO_REF:0000107
NelfaRatnucleus located_inIEAUniProtKB:Q8BG30 and ensembl:ENSMUSP000000309931600115GO_REF:0000107EnsemblGO_REF:0000107
NelfaRatnucleus located_inISONELFA (Homo sapiens)1624291 PMID:12612062RGDPMID:12612062
1 to 13 of 13 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NelfaRatRNA polymerase II transcription elongation pathway  ISONELFA (Homo sapiens)9681735 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II. Saha RN, etal., Nat Neurosci. 2011 May 29;14(7):848-56. doi: 10.1038/nn.2839.
PMID:12477932   PMID:12612062   PMID:19796622   PMID:21670248   PMID:24097989  



Nelfa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,033,470 - 81,057,546 (+)NCBIGRCr8
mRatBN7.21476,808,920 - 76,832,998 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1476,808,870 - 76,832,994 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,260,792 - 81,284,853 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01482,501,435 - 82,525,496 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01478,946,688 - 78,970,749 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,093,837 - 82,117,913 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,093,837 - 82,117,906 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01482,778,077 - 82,802,153 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41482,502,840 - 82,526,916 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11482,505,230 - 82,529,304 (+)NCBI
Celera1475,732,469 - 75,756,545 (+)NCBICelera
Cytogenetic Map14q21NCBI
NELFA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,982,723 - 2,008,974 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl41,982,717 - 2,041,903 (-)EnsemblGRCh38hg38GRCh38
GRCh3741,984,450 - 2,010,701 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,954,248 - 1,980,547 (-)NCBINCBI36Build 36hg18NCBI36
Build 3441,951,683 - 1,977,980NCBI
Celera41,896,671 - 1,923,194 (-)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef41,925,800 - 1,952,332 (-)NCBIHuRef
CHM1_141,983,104 - 2,009,627 (-)NCBICHM1_1
T2T-CHM13v2.041,981,232 - 2,007,492 (-)NCBIT2T-CHM13v2.0
Nelfa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39534,055,263 - 34,093,615 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl534,055,260 - 34,093,757 (-)EnsemblGRCm39 Ensembl
GRCm38533,897,916 - 33,936,301 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,897,916 - 33,936,413 (-)EnsemblGRCm38mm10GRCm38
MGSCv37534,240,828 - 34,278,907 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36534,215,036 - 34,253,115 (-)NCBIMGSCv36mm8
Celera531,375,430 - 31,405,361 (-)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.83NCBI
Nelfa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555141,162,993 - 1,173,278 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555141,162,993 - 1,173,278 (-)NCBIChiLan1.0ChiLan1.0
NELFA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v232,310,013 - 2,374,814 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan142,247,052 - 2,311,265 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v042,119,699 - 2,147,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.142,027,939 - 2,054,669 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl42,027,939 - 2,054,669 (-)Ensemblpanpan1.1panPan2
NELFA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1362,147,948 - 62,164,039 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl362,147,948 - 62,164,112 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha364,665,674 - 64,682,273 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0362,623,281 - 62,639,884 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl362,623,336 - 62,639,877 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1362,115,860 - 62,133,779 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0362,319,512 - 62,337,145 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0362,679,577 - 62,696,178 (+)NCBIUU_Cfam_GSD_1.0
Nelfa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528567,740,863 - 67,758,307 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647721,442,380 - 21,464,005 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647721,442,493 - 21,459,999 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NELFA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl81,018,453 - 1,039,134 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.181,018,443 - 1,039,091 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28515,274 - 626,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NELFA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12746,759,742 - 46,786,835 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2746,760,707 - 46,787,090 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660513,131,850 - 3,158,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nelfa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475525,498,431 - 25,508,753 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475525,498,336 - 25,508,753 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Nelfa
46 total Variants


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
14 82799073 82799074 C T snv LEC/Tj (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), BDIX/NemOda (KyushuU) View more Information

Predicted Target Of
Summary Value
Count of predictions:501
Count of miRNA genes:242
Interacting mature miRNAs:291
Transcripts:ENSRNOT00000021593
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 23 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat

1 to 10 of 23 rows
RH143710  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21476,832,677 - 76,832,884 (+)MAPPERmRatBN7.2
Rnor_6.01482,117,593 - 82,117,799NCBIRnor6.0
Rnor_5.01482,801,833 - 82,802,039UniSTSRnor5.0
RGSC_v3.41482,526,596 - 82,526,802UniSTSRGSC3.4
Celera1475,756,225 - 75,756,431UniSTS
Cytogenetic Map14q21UniSTS
RH137290  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21476,832,751 - 76,832,946 (+)MAPPERmRatBN7.2
Rnor_6.01482,117,667 - 82,117,861NCBIRnor6.0
Rnor_5.01482,801,907 - 82,802,101UniSTSRnor5.0
RGSC_v3.41482,526,670 - 82,526,864UniSTSRGSC3.4
Celera1475,756,299 - 75,756,493UniSTS
Cytogenetic Map14q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000021593   ⟹   ENSRNOP00000021593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1476,808,967 - 76,832,994 (+)Ensembl
Rnor_6.0 Ensembl1482,093,837 - 82,117,906 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118033   ⟹   ENSRNOP00000076832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1476,808,870 - 76,832,988 (+)Ensembl
RefSeq Acc Id: NM_001008339   ⟹   NP_001008340
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,033,470 - 81,057,546 (+)NCBI
mRatBN7.21476,808,920 - 76,832,998 (+)NCBI
Rnor_6.01482,093,837 - 82,117,913 (+)NCBI
Rnor_5.01482,778,077 - 82,802,153 (+)NCBI
RGSC_v3.41482,502,840 - 82,526,916 (+)RGD
Celera1475,732,469 - 75,756,545 (+)RGD
Sequence:
Protein RefSeqs NP_001008340 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85948 (Get FASTA)   NCBI Sequence Viewer  
  EDM00112 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021593
  ENSRNOP00000021593.6
  ENSRNOP00000076832.1
RefSeq Acc Id: NP_001008340   ⟸   NM_001008339
- UniProtKB: Q5U2N1 (UniProtKB/TrEMBL),   F7FPZ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021593   ⟸   ENSRNOT00000021593
Ensembl Acc Id: ENSRNOP00000076832   ⟸   ENSRNOT00000118033
HDAg

Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2N1-F1-model_v2 AlphaFold Q5U2N1 1-530 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699407
Promoter ID:EPDNEW_R9931
Type:initiation region
Name:Nelfa_1
Description:negative elongation factor complex member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01482,093,881 - 82,093,941EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-15271 BioCyc
Ensembl Genes ENSRNOG00000015474 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021593 ENTREZGENE
  ENSRNOT00000021593.6 UniProtKB/TrEMBL
  ENSRNOT00000118033.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7130899 IMAGE-MGC_LOAD
InterPro HDAG_dom UniProtKB/TrEMBL
  NELF-A_domain UniProtKB/TrEMBL
KEGG Report rno:305455 UniProtKB/TrEMBL
MGC_CLONE MGC:95174 IMAGE-MGC_LOAD
NCBI Gene 305455 ENTREZGENE
PANTHER NEGATIVE ELONGATION FACTOR A UniProtKB/TrEMBL
  NEGATIVE ELONGATION FACTOR A NELF-A UniProtKB/TrEMBL
PhenoGen Nelfa PhenoGen
PROSITE HDAG UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015474 RatGTEx
UniProt A0A8I5Y6E2_RAT UniProtKB/TrEMBL
  F7FPZ3 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2N1 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-07 Nelfa  negative elongation factor complex member A  Whsc2  Wolf-Hirschhorn syndrome candidate 2 (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Whsc2  Wolf-Hirschhorn syndrome candidate 2 (human)    Wolf-Hirschhorn syndrome candidate 2  Name updated 1299863 APPROVED
2005-12-06 Whsc2  Wolf-Hirschhorn syndrome candidate 2  Whsc2_predicted  Wolf-Hirschhorn syndrome candidate 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Whsc2_predicted  Wolf-Hirschhorn syndrome candidate 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED