Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Adgra3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Adgra3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ADGRA3 mRNA | CTD | PMID:36331819 | Adgra3 | Rat | 1,1-dichloroethene | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of ADGRA3 mRNA | CTD | PMID:26682919 | Adgra3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Adgra3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADGRA3 mRNA | CTD | PMID:22206623 | Adgra3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of GPR125 mRNA | CTD | PMID:22206623 | Adgra3 | Rat | 17beta-estradiol | affects expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Estradiol affects the expression of ADGRA3 mRNA | CTD | PMID:22574217 | Adgra3 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ADGRA3 mRNA and Estradiol results in decreased expression of GPR125 mRNA | CTD | PMID:32145629 | Adgra3 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:27291303 | Adgra3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADGRA3 mRNA | CTD | PMID:20106945 and PMID:21632981 | Adgra3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADGRA3 mRNA | CTD | PMID:21215274 and PMID:33387578 | Adgra3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] affects the methylation of ADGRA3 gene | CTD | PMID:31601247 | Adgra3 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of ADGRA3 mRNA | CTD | PMID:28959563 | Adgra3 | Rat | aflatoxin B1 | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of ADGRA3 mRNA | CTD | PMID:19770486 | Adgra3 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ADGRA3 mRNA | CTD | PMID:35163327 | Adgra3 | Rat | aristolochic acid A | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ADGRA3 mRNA | CTD | PMID:33212167 | Adgra3 | Rat | benzo[a]pyrene | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ADGRA3 mRNA | CTD | PMID:20064835 | Adgra3 | Rat | benzo[a]pyrene | decreases methylation | ISO | ADGRA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of GPR125 exon | CTD | PMID:27901495 | Adgra3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Adgra3 | Rat | benzo[b]fluoranthene | increases expression | ISO | Adgra3 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of ADGRA3 mRNA | CTD | PMID:26377693 | Adgra3 | Rat | bisphenol A | increases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ADGRA3 mRNA | CTD | PMID:29275510 | Adgra3 | Rat | bisphenol A | decreases methylation | ISO | ADGRA3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ADGRA3 gene | CTD | PMID:31601247 | Adgra3 | Rat | bisphenol A | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ADGRA3 gene | CTD | PMID:31601247 | Adgra3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ADGRA3 mRNA and bisphenol A results in decreased expression of GPR125 mRNA | CTD | PMID:30816183 more ... | Adgra3 | Rat | cadmium atom | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ADGRA3 mRNA | CTD | PMID:35301059 | Adgra3 | Rat | cadmium dichloride | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ADGRA3 mRNA | CTD | PMID:35301059 | Adgra3 | Rat | carbon nanotube | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Adgra3 | Rat | CGP 52608 | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GPR125 gene] | CTD | PMID:28238834 | Adgra3 | Rat | chlorpyrifos | increases expression | ISO | Adgra3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of ADGRA3 mRNA | CTD | PMID:37019170 | Adgra3 | Rat | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of ADGRA3 mRNA | CTD | PMID:22023808 | Adgra3 | Rat | copper(II) sulfate | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ADGRA3 mRNA | CTD | PMID:19549813 | Adgra3 | Rat | cyclosporin A | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ADGRA3 mRNA | CTD | PMID:20106945 and PMID:25562108 | Adgra3 | Rat | cylindrospermopsin | increases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of ADGRA3 mRNA | CTD | PMID:24921660 | Adgra3 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of ADGRA3 mRNA | CTD | PMID:23640034 | Adgra3 | Rat | dexamethasone | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of ADGRA3 mRNA | CTD | PMID:22733784 | Adgra3 | Rat | doxorubicin | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ADGRA3 mRNA | CTD | PMID:29803840 | Adgra3 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ADGRA3 mRNA | CTD | PMID:29391264 | Adgra3 | Rat | ethanol | increases expression | ISO | Adgra3 (Mus musculus) | 6480464 | Ethanol results in increased expression of ADGRA3 mRNA | CTD | PMID:30319688 | Adgra3 | Rat | folic acid | multiple interactions | ISO | Adgra3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADGRA3 mRNA | CTD | PMID:22206623 | Adgra3 | Rat | formaldehyde | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ADGRA3 mRNA | CTD | PMID:23649840 | Adgra3 | Rat | fulvestrant | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ADGRA3 gene and [bisphenol S co-treated with Fulvestrant] affects the methylation of ADGRA3 gene | CTD | PMID:31601247 | Adgra3 | Rat | fulvestrant | increases methylation | ISO | ADGRA3 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of ADGRA3 gene | CTD | PMID:31601247 | Adgra3 | Rat | hydralazine | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of ADGRA3 mRNA | CTD | PMID:17183730 | Adgra3 | Rat | menadione | affects expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ADGRA3 mRNA | CTD | PMID:20044591 | Adgra3 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ADGRA3 gene | CTD | PMID:35440735 | Adgra3 | Rat | methyl methanesulfonate | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ADGRA3 mRNA | CTD | PMID:23649840 | Adgra3 | Rat | N(4)-hydroxycytidine | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | N(4)-hydroxycytidine results in decreased expression of ADGRA3 mRNA | CTD | PMID:37748715 | Adgra3 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of ADGRA3 gene | CTD | PMID:33148267 | Adgra3 | Rat | paracetamol | affects expression | ISO | Adgra3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ADGRA3 mRNA | CTD | PMID:17562736 | Adgra3 | Rat | paracetamol | increases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ADGRA3 mRNA | CTD | PMID:26690555 | Adgra3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Adgra3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ADGRA3 mRNA | CTD | PMID:36331819 | Adgra3 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ADGRA3 mRNA | CTD | PMID:35163327 | Adgra3 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of ADGRA3 gene | CTD | PMID:33148267 | Adgra3 | Rat | phenobarbital | affects expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ADGRA3 mRNA | CTD | PMID:19159669 | Adgra3 | Rat | pirinixic acid | increases expression | ISO | Adgra3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ADGRA3 mRNA | CTD | PMID:18301758 | Adgra3 | Rat | pirinixic acid | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ADGRA3 mRNA | CTD | PMID:18445702 | Adgra3 | Rat | quercetin | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of ADGRA3 mRNA | CTD | PMID:21632981 | Adgra3 | Rat | raloxifene | increases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in increased expression of ADGRA3 mRNA | CTD | PMID:19429434 | Adgra3 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of ADGRA3 mRNA | CTD | PMID:19281266 | Adgra3 | Rat | testosterone | decreases expression | ISO | ADGRA3 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of GPR125 mRNA | CTD | PMID:33359661 | Adgra3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ADGRA3 mRNA | CTD | PMID:31150632 | Adgra3 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ADGRA3 mRNA | CTD | PMID:34492290 | Adgra3 | Rat | triptonide | decreases expression | ISO | Adgra3 (Mus musculus) | 6480464 | triptonide results in decreased expression of ADGRA3 mRNA | CTD | PMID:33045310 | Adgra3 | Rat | valproic acid | multiple interactions | ISO | ADGRA3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of ADGRA3 mRNA | CTD | PMID:17183730 | Adgra3 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of ADGRA3 gene | CTD | PMID:31682807 | |