Hpca (hippocalcin) - Rat Genome Database

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Gene: Hpca (hippocalcin) Mus musculus
Analyze
Symbol: Hpca
Name: hippocalcin
RGD ID: 735422
MGI Page MGI
Description: Predicted to enable several functions, including actin binding activity; calcium ion binding activity; and identical protein binding activity. Acts upstream of or within inner ear development. Predicted to be located in several cellular components, including dendrite; neuronal cell body membrane; and perikaryon. Predicted to be active in glutamatergic synapse and postsynapse. Is expressed in ganglia; salivary gland primordium; and telencephalon. Human ortholog(s) of this gene implicated in torsion dystonia 2. Orthologous to human HPCA (hippocalcin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neuron-specific calcium-binding protein hippocalcin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,005,363 - 129,019,712 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,005,363 - 129,015,829 (-)EnsemblGRCm39 Ensembl
GRCm384129,111,570 - 129,125,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,111,570 - 129,122,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv374128,788,819 - 128,798,984 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,613,879 - 128,621,062 (-)NCBIMGSCv36mm8
Celera4127,451,599 - 127,461,862 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
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Original Reference(s)
HpcaMousecolorectal adenocarcinoma severityISOHPCA (Homo sapiens)9693683mRNA and protein:increased expression:colon carcinoma (human)RGD 
HpcaMouseHuntington's disease  ISOHPCA (Homo sapiens)9693681mRNA:decreased expression:brain (human)RGD 
HpcaMouseisolated growth hormone deficiency  IEP 9693682protein:altered expression:cerebral cortex more ...RGD 
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Original Reference(s)
HpcaMouseCharcot-Marie-Tooth disease dominant intermediate C  ISOHPCA (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate CClinVarPMID:28492532
HpcaMousetorsion dystonia 2  ISOHPCA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14694054 more ...
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Original Reference(s)
HpcaMousetorsion dystonia 2  ISOHPCA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
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Original Reference(s)
HpcaMousetorsion dystonia 2  ISOHPCA (Homo sapiens)7240710 OMIM 

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Original Reference(s)
HpcaMouse(S)-nicotine increases expressionEXP 6480464Nicotine results in increased expression of HPCA mRNACTDPMID:21955143
HpcaMouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of HPCA mRNACTDPMID:21570461
HpcaMouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOHpca (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of HPCA mRNACTDPMID:32109520
HpcaMouse2,3,7,8-Tetrachlorodibenzofuran decreases expressionISOHpca (Rattus norvegicus)64804642 more ...CTDPMID:32109520
HpcaMouse4,4'-sulfonyldiphenol decreases expressionEXP 6480464bisphenol S results in decreased expression of HPCA mRNACTDPMID:30951980
HpcaMouse4,4'-sulfonyldiphenol affects methylationEXP 6480464bisphenol S affects the methylation of HPCA geneCTDPMID:31683443
HpcaMouse4,4'-sulfonyldiphenol decreases methylationEXP 6480464bisphenol S results in decreased methylation of HPCA promoterCTDPMID:33297965
HpcaMouse8-Br-cAMP decreases expressionISOHPCA (Homo sapiens)64804648-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HPCA mRNACTDPMID:22079614
HpcaMouseall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of HPCA mRNACTDPMID:36189433
HpcaMouseall-trans-retinoic acid multiple interactionsEXP 6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HPCA mRNACTDPMID:36189433
HpcaMouseammonium chloride affects expressionISOHpca (Rattus norvegicus)6480464Ammonium Chloride affects the expression of HPCA mRNACTDPMID:16483693
HpcaMousearsenous acid decreases expressionISOHPCA (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of HPCA mRNACTDPMID:20458559
HpcaMousebenzo[a]pyrene decreases expressionISOHPCA (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of HPCA mRNACTDPMID:22316170
HpcaMousebenzo[a]pyrene affects methylationISOHPCA (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of HPCA promoterCTDPMID:27901495
HpcaMousebenzo[a]pyrene increases methylationISOHPCA (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of HPCA 5' UTRCTDPMID:27901495
HpcaMousebenzo[a]pyrene multiple interactionsEXP 6480464AHR protein affects the reaction [Benzo(a)pyrene affects the expression of HPCA mRNA]CTDPMID:22228805
HpcaMousebisphenol A decreases expressionISOHPCA (Homo sapiens)6480464bisphenol A results in decreased expression of HPCA mRNACTDPMID:33670352
HpcaMousebisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of HPCA mRNACTDPMID:32156529
HpcaMousebisphenol A increases methylationISOHPCA (Homo sapiens)6480464bisphenol A results in increased methylation of HPCA geneCTDPMID:31601247
HpcaMousebisphenol F decreases expressionEXP 6480464bisphenol F results in decreased expression of HPCA mRNACTDPMID:38685157

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Biological Process
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Original Reference(s)
HpcaMouseactivation of phospholipase D activity  ISOHpca (Rattus norvegicus)9068941 RGDPMID:11211872 and REF_RGD_ID:9686445
HpcaMousecalcium-mediated signaling  ISOHpca (Rattus norvegicus)9068941 RGDPMID:20704590 and REF_RGD_ID:9686447
HpcaMousecalcium-mediated signaling involved_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousecellular response to calcium ion involved_inISSUniProtKB:P840742290270 UniProtGO_REF:0000024
HpcaMousecellular response to calcium ion involved_inISOUniProtKB:P840742290270 GO_CentralGO_REF:0000119
HpcaMousecellular response to electrical stimulus involved_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousecellular response to electrical stimulus  ISOHpca (Rattus norvegicus)9068941 RGDPMID:20704590 and REF_RGD_ID:9686447
HpcaMousecellular response to L-glutamate involved_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousecellular response to L-glutamate involved_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousecellular response to L-glutamate  ISOHpca (Rattus norvegicus)9068941 RGDPMID:20704590 and REF_RGD_ID:9686447
HpcaMouseinner ear development acts_upstream_of_or_withinIDA 2290270 PMID:21795542MGIPMID:21795542
HpcaMousenegative regulation of guanylate cyclase activity  ISOHpca (Rattus norvegicus)9068941 RGDPMID:15336960 and REF_RGD_ID:9686438
HpcaMousepositive regulation of adenylate cyclase activity  ISOHpca (Rattus norvegicus)9068941 RGDPMID:15336960 and REF_RGD_ID:9686438
HpcaMousepositive regulation of phospholipase activity  ISOHpca (Rattus norvegicus)9068941 RGDPMID:11211872 and REF_RGD_ID:9686445
HpcaMousepositive regulation of protein targeting to membrane  ISOHpca (Rattus norvegicus)9068941 RGDPMID:23142228 and REF_RGD_ID:9686444
HpcaMousepositive regulation of protein targeting to membrane involved_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousepositive regulation of protein targeting to membrane involved_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMouseregulation of postsynaptic neurotransmitter receptor internalization involved_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMouseregulation of postsynaptic neurotransmitter receptor internalization involved_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMouseregulation of signal transduction involved_inIBAPANTHER:PTN008588905 more ...2290270 GO_CentralGO_REF:0000033
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Cellular Component
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Original Reference(s)
HpcaMouseaxon  ISOHpca (Rattus norvegicus)9068941 RGDPMID:7789406 and REF_RGD_ID:9686441
HpcaMouseaxon located_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMouseaxon located_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousecytoplasm located_inISOUniProtKB:P840742290270 GO_CentralGO_REF:0000119
HpcaMousecytoplasm located_inISSUniProtKB:P840742290270 UniProtGO_REF:0000024
HpcaMousecytosol located_inISSUniProtKB:P840762290270 UniProtGO_REF:0000024
HpcaMousecytosol located_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousedendrite cytoplasm located_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousedendrite cytoplasm located_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousedendrite cytoplasm  ISOHpca (Rattus norvegicus)9068941 RGDPMID:8233019 and REF_RGD_ID:9686436
HpcaMousedendrite membrane located_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousedendrite membrane located_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousedendrite membrane  ISOHpca (Rattus norvegicus)9068941 RGDPMID:8233019 and REF_RGD_ID:9686436
HpcaMousedendritic spine head  ISOHpca (Rattus norvegicus)9068941 RGDPMID:20704590 and REF_RGD_ID:9686447
HpcaMousedendritic spine head located_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousedendritic spine head located_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMouseglutamatergic synapse located_inIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMouseglutamatergic synapse is_active_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousemembrane located_inISSUniProtKB:P840762290270 UniProtGO_REF:0000024
HpcaMousemembrane located_inISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
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Molecular Function
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Original Reference(s)
HpcaMouseactin binding enablesISSUniProtKB:P840742290270 UniProtGO_REF:0000024
HpcaMouseactin binding enablesISOUniProtKB:P840742290270 GO_CentralGO_REF:0000119
HpcaMousecalcium ion binding enablesISOUniProtKB:P840742290270 GO_CentralGO_REF:0000119
HpcaMousecalcium ion binding enablesIBAPANTHER:PTN000550679 more ...2290270 GO_CentralGO_REF:0000033
HpcaMousecalcium ion binding enablesISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousecalcium ion binding enablesISSUniProtKB:P840742290270 UniProtGO_REF:0000024
HpcaMouseidentical protein binding enablesISOUniProtKB:P840742290270 GO_CentralGO_REF:0000119
HpcaMouseidentical protein binding enablesISSUniProtKB:P840742290270 UniProtGO_REF:0000024
HpcaMousekinase binding enablesISOHpca (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
HpcaMousekinase binding enablesIEAUniProtKB:P84076 and ensembl:ENSRNOP000000091532290270 EnsemblGO_REF:0000107
HpcaMousekinase binding  ISOCkb (Rattus norvegicus)9068941 RGDPMID:23142228 and REF_RGD_ID:9686444
HpcaMouseprotein binding enablesIPIUniProtKB:Q084602290270 PMID:19423573IntActPMID:19423573
HpcaMouseprotein binding enablesIPIPR:Q3TDX82290270 PMID:14739275MGIPMID:14739275
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Reference Title
Reference Citation
1. Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma. Conesa-Zamora P, etal., Int J Cancer. 2013 Jan 15;132(2):297-307. doi: 10.1002/ijc.27674. Epub 2012 Jun 28.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Diminished hippocalcin expression in Huntington's disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons. Rudinskiy N, etal., J Neurochem. 2009 Oct;111(2):460-72. doi: 10.1111/j.1471-4159.2009.06344.x. Epub 2009 Aug 17.
12. Hippocalcin expression in the brain of the Snell dwarf mutant mouse. Sugisaki T, etal., Brain Res. 1994 Nov 28;665(1):101-6.
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PMID:8889548   PMID:9931466   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11978849   PMID:12477932   PMID:12819125   PMID:14610273   PMID:14739275   PMID:15489334   PMID:15607944  
PMID:15878804   PMID:16141072   PMID:16141073   PMID:16203087   PMID:16602821   PMID:17257765   PMID:17296551   PMID:19398467   PMID:19423573   PMID:21267068   PMID:21795542   PMID:21873635  
PMID:22639951   PMID:22903314   PMID:23142228   PMID:23260046   PMID:24014668   PMID:25752619   PMID:30091036   PMID:30256386   PMID:31845734   PMID:32325033   PMID:34193558   PMID:34321999  
PMID:35831953   PMID:36417873   PMID:37142655   PMID:38355793  



Hpca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,005,363 - 129,019,712 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,005,363 - 129,015,829 (-)EnsemblGRCm39 Ensembl
GRCm384129,111,570 - 129,125,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,111,570 - 129,122,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv374128,788,819 - 128,798,984 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,613,879 - 128,621,062 (-)NCBIMGSCv36mm8
Celera4127,451,599 - 127,461,862 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.88NCBI
HPCA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38132,885,996 - 32,894,646 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl132,885,994 - 32,898,441 (+)EnsemblGRCh38hg38GRCh38
GRCh37133,352,092 - 33,360,247 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,124,685 - 33,132,834 (+)NCBINCBI36Build 36hg18NCBI36
Build 34133,021,190 - 33,029,339NCBI
Celera131,620,733 - 31,628,882 (+)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,467,222 - 31,475,369 (+)NCBIHuRef
CHM1_1133,467,533 - 33,475,680 (+)NCBICHM1_1
T2T-CHM13v2.0132,745,769 - 32,754,441 (+)NCBIT2T-CHM13v2.0
Hpca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,739,978 - 146,750,961 (-)NCBIGRCr8
mRatBN7.25141,455,616 - 141,466,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,455,613 - 141,463,841 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5144,153,733 - 144,162,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05145,923,554 - 145,932,014 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05145,923,306 - 145,931,631 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05147,295,124 - 147,305,757 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,294,820 - 147,303,346 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05151,029,882 - 151,040,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,267,898 - 148,276,223 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15148,277,936 - 148,286,262 (-)NCBI
Celera5139,935,623 - 139,943,977 (-)NCBICelera
Cytogenetic Map5q36NCBI
Hpca
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,140,373 - 11,154,261 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545211,142,282 - 11,150,798 (+)NCBIChiLan1.0ChiLan1.0
HPCA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21193,927,688 - 193,936,359 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11193,049,890 - 193,058,560 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,176,465 - 32,185,133 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,362,921 - 33,371,524 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,363,673 - 33,371,524 (+)Ensemblpanpan1.1panPan2
HPCA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,464,631 - 68,473,661 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,465,280 - 68,473,310 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha265,045,221 - 65,053,618 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0269,030,436 - 69,038,834 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl269,029,808 - 69,039,028 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,841,971 - 65,850,366 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,864,436 - 66,872,823 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,856,319 - 67,864,715 (-)NCBIUU_Cfam_GSD_1.0
Hpca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505849,961,196 - 49,969,278 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647415,785,879 - 15,798,740 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647415,786,171 - 15,794,830 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HPCA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl689,188,133 - 89,197,045 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1689,187,544 - 89,197,049 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,214,827 - 83,224,104 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HPCA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12099,974,952 - 99,983,194 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2099,975,742 - 99,980,728 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603316,708,814 - 16,717,377 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hpca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476415,990,729 - 15,999,615 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476415,990,910 - 15,999,617 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Hpca
710 total Variants

Predicted Target Of
Summary Value
Count of predictions:2418
Count of miRNA genes:531
Interacting mature miRNAs:655
Transcripts:ENSMUST00000030572, ENSMUST00000095807, ENSMUST00000116442, ENSMUST00000116444, ENSMUST00000125931, ENSMUST00000135763, ENSMUST00000139450, ENSMUST00000149763, ENSMUST00000164649
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 66 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse

1 to 10 of 66 rows
AB015200  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384129,112,175 - 129,112,269UniSTSGRCm38
MGSCv374128,789,419 - 128,789,513UniSTSGRCm37
Celera4127,452,201 - 127,452,295UniSTS
Cytogenetic Map4D2-D3UniSTS
Whitehead/MRC_RH41682.5UniSTS
AI507302  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384129,111,384 - 129,111,479UniSTSGRCm38
MGSCv374128,788,628 - 128,788,723UniSTSGRCm37
Celera4127,451,408 - 127,451,503UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic Map4D2-D3UniSTS
Whitehead/MRC_RH41673.6UniSTS
D5Wox35  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384129,111,700 - 129,111,856UniSTSGRCm38
MGSCv374128,788,944 - 128,789,100UniSTSGRCm37
Celera4127,451,724 - 127,451,882UniSTS
Cytogenetic Map4D2-D3UniSTS
Cytogenetic Map4D2.2UniSTS






1 to 30 of 32 rows
RefSeq Transcripts NM_001130419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_185239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_185240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_185241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006502775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB015200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF326551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF326552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI835374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL606977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY128037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY129411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY769297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU210925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX238650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX239660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 32 rows

Ensembl Acc Id: ENSMUST00000030572   ⟹   ENSMUSP00000030572
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,005,369 - 129,015,084 (-)Ensembl
GRCm38.p6 Ensembl4129,111,576 - 129,121,291 (-)Ensembl
Ensembl Acc Id: ENSMUST00000095807   ⟹   ENSMUSP00000093486
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,005,363 - 129,012,760 (-)Ensembl
GRCm38.p6 Ensembl4129,111,570 - 129,118,967 (-)Ensembl
Ensembl Acc Id: ENSMUST00000116442   ⟹   ENSMUSP00000112143
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,006,053 - 129,014,739 (-)Ensembl
GRCm38.p6 Ensembl4129,112,260 - 129,120,946 (-)Ensembl
Ensembl Acc Id: ENSMUST00000116444   ⟹   ENSMUSP00000112145
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,005,363 - 129,015,829 (-)Ensembl
GRCm38.p6 Ensembl4129,111,570 - 129,122,036 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125931   ⟹   ENSMUSP00000115031
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,006,242 - 129,015,718 (-)Ensembl
GRCm38.p6 Ensembl4129,112,449 - 129,121,925 (-)Ensembl
Ensembl Acc Id: ENSMUST00000135763   ⟹   ENSMUSP00000120655
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,012,398 - 129,015,501 (-)Ensembl
GRCm38.p6 Ensembl4129,118,605 - 129,121,708 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139450   ⟹   ENSMUSP00000119178
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,006,067 - 129,015,682 (-)Ensembl
GRCm38.p6 Ensembl4129,112,274 - 129,121,889 (-)Ensembl
Ensembl Acc Id: ENSMUST00000149763   ⟹   ENSMUSP00000115619
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,006,468 - 129,015,532 (-)Ensembl
GRCm38.p6 Ensembl4129,112,675 - 129,121,739 (-)Ensembl
Ensembl Acc Id: ENSMUST00000164649   ⟹   ENSMUSP00000129548
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,005,369 - 129,015,533 (-)Ensembl
GRCm38.p6 Ensembl4129,111,576 - 129,121,740 (-)Ensembl
RefSeq Acc Id: NM_001130419   ⟹   NP_001123891
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,516 (-)NCBI
GRCm384129,111,570 - 129,121,747 (-)NCBI
MGSCv374128,788,819 - 128,798,984 (-)RGD
Celera4127,451,594 - 127,462,047 (-)NCBI
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001286081   ⟹   NP_001273010
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,728 (-)NCBI
GRCm384129,111,570 - 129,121,925 (-)NCBI
Celera4127,451,594 - 127,462,047 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286083   ⟹   NP_001273012
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,516 (-)NCBI
GRCm384129,111,570 - 129,120,172 (-)NCBI
Celera4127,451,594 - 127,462,047 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001421088   ⟹   NP_001408017
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,516 (-)NCBI
RefSeq Acc Id: NM_001421089   ⟹   NP_001408018
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,899 (-)NCBI
RefSeq Acc Id: NM_001421090   ⟹   NP_001408019
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,899 (-)NCBI
RefSeq Acc Id: NM_001421091   ⟹   NP_001408020
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,899 (-)NCBI
RefSeq Acc Id: NM_001421092   ⟹   NP_001408021
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,050 (-)NCBI
RefSeq Acc Id: NM_010471   ⟹   NP_034601
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,050 (-)NCBI
GRCm384129,111,570 - 129,121,303 (-)NCBI
MGSCv374128,788,819 - 128,798,984 (-)RGD
Celera4127,451,594 - 127,462,047 (-)NCBI
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_185239
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,019,700 (-)NCBI
RefSeq Acc Id: NR_185240
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,019,705 (-)NCBI
RefSeq Acc Id: NR_185241
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,016,336 (-)NCBI
RefSeq Acc Id: XM_006502775   ⟹   XP_006502838
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,894 (-)NCBI
GRCm384129,111,570 - 129,122,101 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253224   ⟹   XP_030109084
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,019,712 (-)NCBI
GRCm384129,111,570 - 129,125,919 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253225   ⟹   XP_030109085
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,005,363 - 129,015,616 (-)NCBI
GRCm384129,111,570 - 129,121,823 (-)NCBI
Sequence:
1 to 30 of 32 rows
Protein RefSeqs NP_001123891 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273010 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273012 (Get FASTA)   NCBI Sequence Viewer  
  NP_001408017 (Get FASTA)   NCBI Sequence Viewer  
  NP_001408018 (Get FASTA)   NCBI Sequence Viewer  
  NP_001408019 (Get FASTA)   NCBI Sequence Viewer  
  NP_001408020 (Get FASTA)   NCBI Sequence Viewer  
  NP_001408021 (Get FASTA)   NCBI Sequence Viewer  
  NP_034601 (Get FASTA)   NCBI Sequence Viewer  
  XP_006502838 (Get FASTA)   NCBI Sequence Viewer  
  XP_030109084 (Get FASTA)   NCBI Sequence Viewer  
  XP_030109085 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH49607 (Get FASTA)   NCBI Sequence Viewer  
  AAH58588 (Get FASTA)   NCBI Sequence Viewer  
  AAL37397 (Get FASTA)   NCBI Sequence Viewer  
  AAL37398 (Get FASTA)   NCBI Sequence Viewer  
  BAA74455 (Get FASTA)   NCBI Sequence Viewer  
  BAB22502 (Get FASTA)   NCBI Sequence Viewer  
  EDL30215 (Get FASTA)   NCBI Sequence Viewer  
  EDL30216 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000030572
  ENSMUSP00000030572.4
  ENSMUSP00000093486.4
  ENSMUSP00000112143
  ENSMUSP00000112143.3
  ENSMUSP00000112145
  ENSMUSP00000112145.3
  ENSMUSP00000119178
  ENSMUSP00000119178.3
  ENSMUSP00000129548
1 to 30 of 32 rows
1 to 5 of 21 rows
1 to 5 of 21 rows
RefSeq Acc Id: NP_034601   ⟸   NM_010471
- Peptide Label: isoform 1
- UniProtKB: A2A7R4 (UniProtKB/Swiss-Prot),   P84075 (UniProtKB/Swiss-Prot),   E9PV73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123891   ⟸   NM_001130419
- Peptide Label: isoform 1
- UniProtKB: A2A7R4 (UniProtKB/Swiss-Prot),   P84075 (UniProtKB/Swiss-Prot),   E9PV73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273010   ⟸   NM_001286081
- Peptide Label: isoform 1
- UniProtKB: A2A7R4 (UniProtKB/Swiss-Prot),   P84075 (UniProtKB/Swiss-Prot),   E9PV73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273012   ⟸   NM_001286083
- Peptide Label: isoform 1
- UniProtKB: A2A7R4 (UniProtKB/Swiss-Prot),   P84075 (UniProtKB/Swiss-Prot),   E9PV73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502838   ⟸   XM_006502775
- Peptide Label: isoform X1
- UniProtKB: A2A7R4 (UniProtKB/Swiss-Prot),   P84075 (UniProtKB/Swiss-Prot),   E9PV73 (UniProtKB/TrEMBL)
- Sequence:
EF-hand

Name Modeler Protein Id AA Range Protein Structure
AF-P84075-F1-model_v2 AlphaFold P84075 1-193 view protein structure

RGD ID:6884734
Promoter ID:EPDNEW_M5818
Type:initiation region
Name:Hpca_1
Description:Mus musculus hippocalcin , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384129,121,246 - 129,121,306EPDNEW


1 to 39 of 39 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000028785 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030572 ENTREZGENE
  ENSMUST00000030572.10 UniProtKB/Swiss-Prot
  ENSMUST00000095807.10 UniProtKB/Swiss-Prot
  ENSMUST00000116442 ENTREZGENE
  ENSMUST00000116442.9 UniProtKB/Swiss-Prot
  ENSMUST00000116444 ENTREZGENE
  ENSMUST00000116444.10 UniProtKB/Swiss-Prot
  ENSMUST00000139450 ENTREZGENE
  ENSMUST00000139450.8 UniProtKB/Swiss-Prot
  ENSMUST00000164649 ENTREZGENE
  ENSMUST00000164649.8 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Recoverin UniProtKB/Swiss-Prot
KEGG Report mmu:15444 UniProtKB/Swiss-Prot
MGD MGI:1336200 ENTREZGENE
NCBI Gene 15444 ENTREZGENE
PANTHER NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN UniProtKB/Swiss-Prot
  PTHR23055 UniProtKB/Swiss-Prot
Pfam EF-hand_1 UniProtKB/Swiss-Prot
  EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Hpca PhenoGen
PRINTS RECOVERIN UniProtKB/Swiss-Prot
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A2A7R4 ENTREZGENE
  A2A7R5_MOUSE UniProtKB/TrEMBL
  A2A7R6_MOUSE UniProtKB/TrEMBL
  E9PV73 ENTREZGENE, UniProtKB/TrEMBL
  HPCA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A2A7R4 UniProtKB/Swiss-Prot
  P32076 UniProtKB/Swiss-Prot
  P41211 UniProtKB/Swiss-Prot
  P70510 UniProtKB/Swiss-Prot
1 to 39 of 39 rows