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Gene: HPCA (hippocalcin) Canis lupus familiaris

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Symbol:

HPCA

Name:

hippocalcin

RGD ID:

12181497

Description:

ENCODES a protein that exhibits kinase binding (ortholog); INVOLVED IN activation of phospholipase D activity (ortholog); calcium-mediated signaling (ortholog); cellular response to electrical stimulus (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); colorectal adenocarcinoma (ortholog); Huntington's disease (ortholog); FOUND IN axon (ortholog); dendrite cytoplasm (ortholog); dendrite membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neuron-specific calcium-binding protein hippocalcin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HPCA (hippocalcin)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Hpca (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hpca (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hpca (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HPCA (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hpca (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HPCA (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HPCA (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hpca (hippocalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	68,464,631 - 68,473,661 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	68,465,280 - 68,473,310 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	65,045,221 - 65,053,618 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	69,030,436 - 69,038,834 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	69,029,808 - 69,039,028 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	65,841,971 - 65,850,366 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	66,864,436 - 66,872,823 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	67,856,319 - 67,864,715 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HPCA	Dog	colorectal adenocarcinoma	severity	ISO	RGD:735421	9068941	mRNA, protein:increased expression:colon carcinoma (human)	RGD	PMID:22696308\|REF_RGD_ID:9693683
HPCA	Dog	Huntington's disease		ISO	RGD:735421	9068941	mRNA:decreased expression:brain (human)	RGD	PMID:19686238\|REF_RGD_ID:9693681
HPCA	Dog	isolated growth hormone deficiency		ISO	RGD:735422	9068941	protein:altered expression:cerebral cortex, cerebellum, hippocampus (mouse)	RGD	PMID:7882001\|REF_RGD_ID:9693682

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HPCA	Dog	Charcot-Marie-Tooth disease dominant intermediate C		ISO	RGD:735421	8554872	ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate C	ClinVar	PMID:28492532
HPCA	Dog	torsion dystonia 2		ISO	RGD:735421	8554872	ClinVar Annotator: match by term: HPCA-related condition \| ClinVar Annotator: match by term: Torsion dystonia more ...	ClinVar	PMID:14694054\|PMID:25741868\|PMID:25799108\|PMID:28492532\|PMID:6115727

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HPCA	Dog	torsion dystonia 2		ISO	RGD:735421	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HPCA	Dog	activation of phospholipase D activity		ISO	RGD:620060	9068941		RGD	PMID:11211872\|REF_RGD_ID:9686445
HPCA	Dog	calcium-mediated signaling		ISO	RGD:620060	9068941		RGD	PMID:20704590\|REF_RGD_ID:9686447
HPCA	Dog	cellular response to calcium ion	involved_in	IEA	UniProtKB:P84074\|ensembl:ENSP00000362566	150520179		Ensembl	GO_REF:0000107
HPCA	Dog	cellular response to electrical stimulus		ISO	RGD:620060	9068941		RGD	PMID:20704590\|REF_RGD_ID:9686447
HPCA	Dog	cellular response to L-glutamate		ISO	RGD:620060	9068941		RGD	PMID:20704590\|REF_RGD_ID:9686447
HPCA	Dog	inner ear development	acts_upstream_of_or_within	IEA	UniProtKB:P84075\|ensembl:ENSMUSP00000112145	150520179		Ensembl	GO_REF:0000107
HPCA	Dog	negative regulation of guanylate cyclase activity		ISO	RGD:620060	9068941		RGD	PMID:15336960\|REF_RGD_ID:9686438
HPCA	Dog	positive regulation of adenylate cyclase activity		ISO	RGD:620060	9068941		RGD	PMID:15336960\|REF_RGD_ID:9686438
HPCA	Dog	positive regulation of phospholipase activity		ISO	RGD:620060	9068941		RGD	PMID:11211872\|REF_RGD_ID:9686445
HPCA	Dog	positive regulation of protein targeting to membrane		ISO	RGD:620060	9068941		RGD	PMID:23142228\|REF_RGD_ID:9686444
HPCA	Dog	regulation of postsynaptic neurotransmitter receptor internalization	involved_in	ISO	RGD:620060	9068941	PMID:20852624	SynGO	PMID:20852624\|REF_RGD_ID:13702412
HPCA	Dog	regulation of signal transduction	involved_in	IBA	FB:FBgn0013303\|PANTHER:PTN008588905\|RGD:1308712\|RGD:68417\|SGD:S000002781	150520179		GO_Central	GO_REF:0000033
HPCA	Dog	regulation of voltage-gated calcium channel activity	involved_in	ISO	RGD:735421	9068941	PMID:28398555	UniProt	PMID:28398555
HPCA	Dog	response to Aroclor 1254		ISO	RGD:620060	9068941		RGD	PMID:18602130\|REF_RGD_ID:2303788
HPCA	Dog	response to ketamine		ISO	RGD:620060	9068941		RGD	PMID:12614903\|REF_RGD_ID:9686446
HPCA	Dog	response to L-glutamate		ISO	RGD:620060	9068941		RGD	PMID:20704590\|REF_RGD_ID:9686447
HPCA	Dog	retina development in camera-type eye		ISO	RGD:620060	9068941		RGD	PMID:7789406\|REF_RGD_ID:9686441

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HPCA	Dog	axon		ISO	RGD:620060	9068941		RGD	PMID:7789406\|REF_RGD_ID:9686441
HPCA	Dog	cytoplasm	located_in	IEA	UniProtKB:P84074\|ensembl:ENSP00000362566	150520179		Ensembl	GO_REF:0000107
HPCA	Dog	cytosol	located_in	IEA	UniProtKB-SubCell:SL-0091	150520179		UniProt	GO_REF:0000044
HPCA	Dog	dendrite cytoplasm		ISO	RGD:620060	9068941		RGD	PMID:8233019\|REF_RGD_ID:9686436
HPCA	Dog	dendrite membrane		ISO	RGD:620060	9068941		RGD	PMID:8233019\|REF_RGD_ID:9686436
HPCA	Dog	dendritic spine head		ISO	RGD:620060	9068941		RGD	PMID:20704590\|REF_RGD_ID:9686447
HPCA	Dog	glutamatergic synapse	is_active_in	ISO	RGD:620060	9068941	PMID:20704590	SynGO	PMID:20704590\|REF_RGD_ID:9686447
HPCA	Dog	glutamatergic synapse	is_active_in	ISO	RGD:620060	9068941	PMID:20852624	SynGO	PMID:20852624\|REF_RGD_ID:13702412
HPCA	Dog	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	150520179		UniProt	GO_REF:0000044
HPCA	Dog	neuronal cell body membrane		ISO	RGD:620060	9068941		RGD	PMID:8233019\|REF_RGD_ID:9686436
HPCA	Dog	perikaryon		ISO	RGD:620060	9068941		RGD	PMID:8233019\|REF_RGD_ID:9686436
HPCA	Dog	postsynapse	is_active_in	ISO	RGD:620060	9068941	PMID:20704590	SynGO	PMID:20704590\|REF_RGD_ID:9686447

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HPCA	Dog	actin binding	enables	IEA	UniProtKB:P84074\|ensembl:ENSP00000362566	150520179		Ensembl	GO_REF:0000107
HPCA	Dog	calcium ion binding	enables	IEA	InterPro:IPR002048\|InterPro:IPR028846	150520179		InterPro	GO_REF:0000002
HPCA	Dog	calcium ion binding	enables	IBA	FB:FBgn0013303\|FB:FBgn0030897\|FB:FBgn0083228\|MGI:1929258\|MGI:1933131\|MGI:97883\|PANTHER:PTN000550679\|PomBase:SPAC18B11.04\|RGD:620060\|RGD:620258\|RGD:68417\|RGD:70886\|RGD:70887\|UniProtKB:P46065\|UniProtKB:P84074\|UniProtKB:Q6PIL6\|UniProtKB:Q8T893\|UniProtKB:Q9NZI2\|ZFIN:ZDB-GENE-011128-5\|ZFIN:ZDB-GENE-011128-6\|ZFIN:ZDB-GENE-030829-1\|ZFIN:ZDB-GENE-040426-1577\|ZFIN:ZDB-GENE-040724-231\|ZFIN:ZDB-GENE-050120-1\|dictyBase:DDB_G0270210\|dictyBase:DDB_G0275931	150520179		GO_Central	GO_REF:0000033
HPCA	Dog	calcium ion binding	enables	IEA	UniProtKB:P84074\|ensembl:ENSP00000362566	150520179		Ensembl	GO_REF:0000107
HPCA	Dog	identical protein binding	enables	IEA	UniProtKB:P84074\|ensembl:ENSP00000362566	150520179		Ensembl	GO_REF:0000107
HPCA	Dog	kinase binding		ISO	RGD:2357	9068941		RGD	PMID:23142228\|REF_RGD_ID:9686444
HPCA	Dog	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
HPCA	Dog	protein binding	enables	ISO	UniProtKB:P14100	9068941	PMID:16470652	IntAct	PMID:16470652\|REF_RGD_ID:8554798
HPCA	Dog	protein binding	enables	ISO	UniProtKB:Q08460	9068941	PMID:19423573	IntAct	PMID:19423573
HPCA	Dog	protein binding	enables	ISO	PR:Q3TDX8	9068941	PMID:14739275	MGI	PMID:14739275
HPCA	Dog	protein binding	enables	ISO	UniProtKB:O15427\|UniProtKB:P0CG20\|UniProtKB:P12532\|UniProtKB:P14927\|UniProtKB:P55197-2\|UniProtKB:Q03060-25\|UniProtKB:Q2TAL6\|UniProtKB:Q86UW9\|UniProtKB:Q969H8\|UniProtKB:Q96N21\|UniProtKB:Q9BWX5\|UniProtKB:Q9BXJ5\|UniProtKB:Q9UBH0	9068941	PMID:32296183	IntAct	PMID:32296183
HPCA	Dog	protein binding	enables	ISO	UniProtKB:Q86UW9	9068941	PMID:33961781	IntAct	PMID:33961781

PMID:22301074	PMID:30032202

HPCA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	68,464,631 - 68,473,661 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	68,465,280 - 68,473,310 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	65,045,221 - 65,053,618 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	69,030,436 - 69,038,834 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	69,029,808 - 69,039,028 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	65,841,971 - 65,850,366 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	66,864,436 - 66,872,823 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	67,856,319 - 67,864,715 (-)	NCBI		UU_Cfam_GSD_1.0

HPCA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	32,885,996 - 32,894,646 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	32,885,994 - 32,898,441 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	33,352,092 - 33,360,247 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	33,124,685 - 33,132,834 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	33,021,190 - 33,029,339	NCBI
Celera	1	31,620,733 - 31,628,882 (+)	NCBI		Celera
Cytogenetic Map	1	p35.1	NCBI
HuRef	1	31,467,222 - 31,475,369 (+)	NCBI		HuRef
CHM1_1	1	33,467,533 - 33,475,680 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	32,745,769 - 32,754,441 (+)	NCBI		T2T-CHM13v2.0

Hpca
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	129,005,363 - 129,019,712 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	129,005,363 - 129,015,829 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	129,111,570 - 129,125,919 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	129,111,570 - 129,122,036 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	128,788,819 - 128,798,984 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	128,613,879 - 128,621,062 (-)	NCBI		MGSCv36	mm8
Celera	4	127,451,599 - 127,461,862 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	62.88	NCBI

Hpca
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	146,739,978 - 146,750,961 (-)	NCBI		GRCr8
mRatBN7.2	5	141,455,616 - 141,466,252 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	141,455,613 - 141,463,841 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	144,153,733 - 144,162,193 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	145,923,554 - 145,932,014 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	145,923,306 - 145,931,631 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	147,295,124 - 147,305,757 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	147,294,820 - 147,303,346 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	151,029,882 - 151,040,514 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	148,267,898 - 148,276,223 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	148,277,936 - 148,286,262 (-)	NCBI
Celera	5	139,935,623 - 139,943,977 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Hpca
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	11,140,373 - 11,154,261 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	11,142,282 - 11,150,798 (+)	NCBI	ChiLan1.0	ChiLan1.0

HPCA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	193,927,688 - 193,936,359 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	193,049,890 - 193,058,560 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	32,176,465 - 32,185,133 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	33,362,921 - 33,371,524 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	33,363,673 - 33,371,524 (+)	Ensembl	panpan1.1		panPan2

Hpca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	49,961,196 - 49,969,278 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	15,785,879 - 15,798,740 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	15,786,171 - 15,794,830 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HPCA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	89,188,133 - 89,197,045 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	89,187,544 - 89,197,049 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	83,214,827 - 83,224,104 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HPCA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	99,974,952 - 99,983,194 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	99,975,742 - 99,980,728 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	16,708,814 - 16,717,377 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hpca
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	15,990,729 - 15,999,615 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	15,990,910 - 15,999,617 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in HPCA
84 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_005617615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022411818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038461662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_849499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000016577 ⟹ ENSCAFP00000015339

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	68,465,280 - 68,473,310 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845009442 ⟹ ENSCAFP00845007388

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	69,029,808 - 69,038,222 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845009448 ⟹ ENSCAFP00845007392

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	69,029,808 - 69,037,725 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845009451 ⟹ ENSCAFP00845007395

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	69,029,810 - 69,039,028 (-)	Ensembl

RefSeq Acc Id:

XM_005617615 ⟹ XP_005617672

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	68,465,262 - 68,473,661 (-)	NCBI
Dog10K_Boxer_Tasha	2	65,045,221 - 65,053,618 (-)	NCBI

Sequence:

show sequence

GATCCCGGGCGGTAGGCAGGAGATGGGGGCGGGGCTCTCTAAGGCCGAGGTAGGGTAGGGGGCGTGTCTTTCCCCCGAAGACCTCCGGGACCGGAGGAGTGGGCGCTGCCCCTCGCGGAAGAGCCCCC
AGCTCAATTAGTTCCCGAGTTGAGGCGCGGGGGCAGGGAAGGTGCCTATCCAACCGCCCAGGCTCCGGATTCCGCCCGCGGAGCGACGTGCAGCTCCGCGCACAGGTGGGACTTGGCTTGGTGGCCAT
GGGCAAGCAGAACAGCAAGCTGCGGCCGGAGATGCTGCAGGACCTGCGGGAGAACACGGAGTTCTCGGAGCTGGAGCTTCAGGAGTGGTACAAGGGCTTCCTCAAGGACTGTCCCACGGGCATCCTCA
ACGTGGACGAGTTCAAGAAGATCTACGCCAACTTCTTCCCCTATGGTGACGCCTCTAAATTTGCTGAGCACGTCTTCCGTACGTTCGACACCAACAGCGATGGCACCATTGACTTCCGGGAGTTCATC
ATCGCGCTGAGTGTGACCTCACGTGGCCGCCTGGAGCAGAAGCTCATGTGGGCCTTCAGCATGTATGACCTGGATGGCAACGGCTACATCAGCCGCGAGGAGATGCTCGAGATTGTGCAGGCCATTTA
CAAGATGGTTTCGTCCGTAATGAAGATGCCGGAGGACGAGTCGACCCCAGAAAAGAGGACCGAGAAGATCTTCCGCCAAATGGACACGAACAACGACGGCAAGCTGTCCCTGGAGGAGTTCATCCGCG
GAGCCAAAAGCGACCCGTCCATCGTGCGTCTGCTGCAGTGCGACCCCAGCAGCGCCTCCCAGTTCTGAGCGAGAGGACCCAGGTTCCCCCTCCTCCCTGCCTTCACTGGCCCTCTCCCGGCTCTCAGC
TTCCTCTCCCTTGTGTCTGTCCAGCCTGGGGGTCAGACTGGGCTCCCCCAGGGCCTGCATTCCGGGGTCTATGGAGAAGGGAACCCCGCGGTAGCCCCAATGCCCAAGCAAGCAAGCGGTCAGCACCT
CCCGTCGAGGCA

hide sequence

RefSeq Acc Id:

XM_038461662 ⟹ XP_038317590

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	2	65,045,221 - 65,052,785 (-)	NCBI

RefSeq Acc Id:

XM_038470336 ⟹ XP_038326264

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	65,841,971 - 65,849,789 (-)	NCBI

RefSeq Acc Id:

XM_038470337 ⟹ XP_038326265

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	65,841,971 - 65,849,538 (-)	NCBI

RefSeq Acc Id:

XM_038470338 ⟹ XP_038326266

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	65,841,971 - 65,850,366 (-)	NCBI

RefSeq Acc Id:

XM_038531181 ⟹ XP_038387109

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	67,856,319 - 67,864,138 (-)	NCBI

RefSeq Acc Id:

XM_038531182 ⟹ XP_038387110

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	67,856,319 - 67,863,885 (-)	NCBI

RefSeq Acc Id:

XM_038531183 ⟹ XP_038387111

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	67,856,319 - 67,864,715 (-)	NCBI

RefSeq Acc Id:

XM_038595403 ⟹ XP_038451331

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	66,864,436 - 66,871,991 (-)	NCBI

RefSeq Acc Id:

XM_038595405 ⟹ XP_038451333

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	66,864,436 - 66,872,823 (-)	NCBI

RefSeq Acc Id:

XM_038595406 ⟹ XP_038451334

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	66,864,436 - 66,872,278 (-)	NCBI

RefSeq Acc Id:

XM_038659484 ⟹ XP_038515412

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	69,030,436 - 69,038,257 (-)	NCBI

RefSeq Acc Id:

XM_038659485 ⟹ XP_038515413

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	69,030,436 - 69,038,004 (-)	NCBI

RefSeq Acc Id:

XM_038659486 ⟹ XP_038515414

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	69,030,436 - 69,038,834 (-)	NCBI

RefSeq Acc Id:

XM_849499 ⟹ XP_854592

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	68,464,631 - 68,473,105 (-)	NCBI
Dog10K_Boxer_Tasha	2	65,045,221 - 65,053,040 (-)	NCBI

Sequence:

show sequence

GCAGTCCCTCCCCCCGCCCCCCGCCCGCCCCTCCGGCCGCCTCTGCCGCCGCGCGCCGCAGCAG
CGCCGCCTTCCCTGCGCAGTCGGTGTCTCCGCGTCGCTGGGTGGGACTTGGCTTGGTGGCCATGGGCAAGCAGAACAGCAAGCTGCGGCCGGAGATGCTGCAGGACCTGCGGGAGAACACGGAGTTCT
CGGAGCTGGAGCTTCAGGAGTGGTACAAGGGCTTCCTCAAGGACTGTCCCACGGGCATCCTCAACGTGGACGAGTTCAAGAAGATCTACGCCAACTTCTTCCCCTATGGTGACGCCTCTAAATTTGCT
GAGCACGTCTTCCGTACGTTCGACACCAACAGCGATGGCACCATTGACTTCCGGGAGTTCATCATCGCGCTGAGTGTGACCTCACGTGGCCGCCTGGAGCAGAAGCTCATGTGGGCCTTCAGCATGTA
TGACCTGGATGGCAACGGCTACATCAGCCGCGAGGAGATGCTCGAGATTGTGCAGGCCATTTACAAGATGGTTTCGTCCGTAATGAAGATGCCGGAGGACGAGTCGACCCCAGAAAAGAGGACCGAGA
AGATCTTCCGCCAAATGGACACGAACAACGACGGCAAGCTGTCCCTGGAGGAGTTCATCCGCGGAGCCAAAAGCGACCCGTCCATCGTGCGTCTGCTGCAGTGCGACCCCAGCAGCGCCTCCCAGTTC
TGAGCGAGAGGACCCAGGTTCCCCCTCCTCCCTGCCTTCACTGGCCCTCTCCCGGCTCTCAGCTTCCTCTCCCTTGTGTCTGTCCAGCCTGGGGGTCAGACTGGGCTCCCCCAGGGCCTGCATTCCGG
GGTCTATGGAGAAGGGAACCCCGCGGTAGCCCCAATGCCCAAGCAAGCAAGCGGTCAGCACCTCCCGTCGAGGCAGTAGCTCCCTGAGGCCGTGGTTGAGACGCAGGCTCTGGCTGGGTCAGCCTTCT
CTTACCATTCTCCTGCCCCCCCCCACCCCGCCCCTACCCGCAGCCTCAAGCTCCTCCCCGAGCCCCCACCCAGCTCTAGTAGCTCTCCGTTAGGGTGGAGGGGGAATCATGCCCAGGTGAGGAGGCTG
TCTTCATTTGGAAAGAAGAGAAGGATTCCAGAGGTGTTTGAGGAAAAAGCTTCCTTGAGCAGTCCTTCCCTGCAGGAAGGCCTCAACTCTTCCTGTTCCGCTGCTTTTGTCGGGCCTGGAGGCCAGGA
TGCAAAGGAGAACCTCCCAGTCCAGCCTCCCAGCTGTGGGTCCCATGAACCCCTACCTGCCTTTCAGCACTTGGATGAACACAGACCCACTGATCCTTCTGTGTAGTTTTCCTCTCTCAGACACACAC
ATGCACACACACACACACACACACACACACACAGGCCCACGGATGGGCAGACACACCCAGAGCCCCACCCACAGCATCCTGTGTGGGAAAGAAGCACAGGCCCCCTGGCCAAGTCCCCGCCCCTGCTG
CATGCATCCATGTGGAGCATCTCTGTTCTTTTTAATAACTTCAGAATAAAGTCTCATTTCAGCGCA

hide sequence


Protein RefSeqs	XP_005617672	(Get FASTA)	NCBI Sequence Viewer
	XP_038317590	(Get FASTA)	NCBI Sequence Viewer
	XP_038326264	(Get FASTA)	NCBI Sequence Viewer
	XP_038326265	(Get FASTA)	NCBI Sequence Viewer
	XP_038326266	(Get FASTA)	NCBI Sequence Viewer
	XP_038387109	(Get FASTA)	NCBI Sequence Viewer
	XP_038387110	(Get FASTA)	NCBI Sequence Viewer
	XP_038387111	(Get FASTA)	NCBI Sequence Viewer
	XP_038451331	(Get FASTA)	NCBI Sequence Viewer
	XP_038451333	(Get FASTA)	NCBI Sequence Viewer
	XP_038451334	(Get FASTA)	NCBI Sequence Viewer
	XP_038515412	(Get FASTA)	NCBI Sequence Viewer
	XP_038515413	(Get FASTA)	NCBI Sequence Viewer
	XP_038515414	(Get FASTA)	NCBI Sequence Viewer
	XP_854592	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000015339.3
	ENSCAFP00000072736.1
	ENSCAFP00000073969.1
	ENSCAFP00030024930.1
	ENSCAFP00845007388
	ENSCAFP00845007388.1
	ENSCAFP00845007392.1
	ENSCAFP00845007395.1

RefSeq Acc Id:	XP_854592 ⟸ XM_849499
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LHZ4 (UniProtKB/TrEMBL), A0A8I3MZQ6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAI YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF hide sequence

RefSeq Acc Id:	XP_005617672 ⟸ XM_005617615
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LHZ4 (UniProtKB/TrEMBL), A0A8I3MZQ6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAI YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF hide sequence

Ensembl Acc Id:

ENSCAFP00000015339 ⟸ ENSCAFT00000016577

RefSeq Acc Id:	XP_038326266 ⟸ XM_038470338
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038326264 ⟸ XM_038470336
- Peptide Label:	isoform X2

Protein Domains

EF-hand

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000010425	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030015512	UniProtKB/TrEMBL
	ENSCAFG00845005304	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000016577.5	UniProtKB/TrEMBL
	ENSCAFT00000100420.1	UniProtKB/TrEMBL
	ENSCAFT00000108543.1	UniProtKB/TrEMBL
	ENSCAFT00030028587.1	UniProtKB/TrEMBL
	ENSCAFT00845009442	ENTREZGENE
	ENSCAFT00845009442.1	UniProtKB/TrEMBL
	ENSCAFT00845009448.1	UniProtKB/TrEMBL
	ENSCAFT00845009451.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	Recoverin	UniProtKB/TrEMBL
NCBI Gene	HPCA	ENTREZGENE
PANTHER	NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN	UniProtKB/TrEMBL
	PTHR23055	UniProtKB/TrEMBL
Pfam	EF-hand_1	UniProtKB/TrEMBL
	EF-hand_7	UniProtKB/TrEMBL
PRINTS	RECOVERIN	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A8C0LHZ4	ENTREZGENE
	A0A8C0RKX5_CANLF	UniProtKB/TrEMBL
	A0A8I3MVD1_CANLF	UniProtKB/TrEMBL
	A0A8I3MY83_CANLF	UniProtKB/TrEMBL
	A0A8I3MZQ6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0PQD5_CANLF	UniProtKB/TrEMBL
	A0A8P0TRU3_CANLF	UniProtKB/TrEMBL
UniProt Secondary	A0A8P0SFJ5	UniProtKB/TrEMBL
VGNC ID	VGNC:52136	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar

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