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Gene: HPCA (hippocalcin) Homo sapiens
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Symbol: HPCA
Name: hippocalcin
Description: Exhibits actin binding activity; calcium ion binding activity; and identical protein binding activity. Involved in cellular response to calcium ion and regulation of voltage-gated calcium channel activity. Localizes to the cytoplasm. Implicated in torsion dystonia 2. Biomarker of Huntington's disease and colorectal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDR2; calcium-binding protein BDR-2; dystonia 2, torsion (autosomal recessive); DYT2; neuron specific calcium-binding protein hippocalcin; neuron-specific calcium-binding protein hippocalcin
Orthologs:
Mus musculus (house mouse) : Hpca (hippocalcin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hpca (hippocalcin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpca (hippocalcin)
Pan paniscus (bonobo/pygmy chimpanzee) : HPCA (hippocalcin)
Canis lupus familiaris (dog) : HPCA (hippocalcin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpca (hippocalcin)
Sus scrofa (pig) : HPCA (hippocalcin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl132,885,994 - 32,898,441 (+)Ensembl
GRCh38132,885,965 - 32,894,646 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37133,351,688 - 33,360,247 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,124,685 - 33,132,834 (+)NCBINCBI36hg18NCBI36
Build 34133,021,190 - 33,029,339NCBI
Celera131,620,733 - 31,628,882 (+)NCBI
Cytogenetic Map1p35.1NCBI
HuRef131,467,222 - 31,475,369 (+)NCBIHuRef
CHM1_1133,467,533 - 33,475,680 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HPCA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735421
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.