WFS1 (wolframin ER transmembrane glycoprotein) - Rat Genome Database

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Gene: WFS1 (wolframin ER transmembrane glycoprotein) Homo sapiens
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Symbol: WFS1
Name: wolframin ER transmembrane glycoprotein
RGD ID: 731649
HGNC Page HGNC:12762
Description: Enables ATPase binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of ATF6-mediated unfolded protein response; negative regulation of apoptotic process; and protein stabilization. Located in endoplasmic reticulum membrane and secretory granule. Implicated in several diseases, including Wolfram syndrome (multiple); auditory system disease (multiple); cataract 41; diabetes mellitus (multiple); and optic atrophy (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CTRCT41; FLJ51211; WFRS; WFS; WFSL; Wolfram syndrome 1 (wolframin); wolframin
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3846,269,850 - 6,303,265 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl46,269,849 - 6,303,265 (+)EnsemblGRCh38hg38GRCh38
GRCh3746,271,577 - 6,304,992 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3646,322,478 - 6,355,893 (+)NCBINCBI36Build 36hg18NCBI36
Build 3446,389,648 - 6,423,064NCBI
Celera46,172,234 - 6,205,670 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef46,205,316 - 6,238,436 (+)NCBIHuRef
CHM1_146,269,525 - 6,302,942 (+)NCBICHM1_1
T2T-CHM13v2.046,243,866 - 6,277,297 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model