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Gene: PENK (proenkephalin) Homo sapiens
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Symbol: PENK
Name: proenkephalin
Description: Predicted to have opioid receptor binding activity. Predicted to be involved in chemical synaptic transmission and neuropeptide signaling pathway. Predicted to localize to several cellular components, including the axon terminus; dendrite; and neuronal cell body.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: enkephalin A; PE; PENK-A; peptide F; preproenkephalin; proenkephalin-A
Orthologs:
Mus musculus (house mouse) : Penk (preproenkephalin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Penk (proenkephalin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Penk (proenkephalin)
Pan paniscus (bonobo/pygmy chimpanzee) : PENK (proenkephalin)
Canis lupus familiaris (dog) : PENK (proenkephalin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Penk (proenkephalin)
Sus scrofa (pig) : PENK (proenkephalin)
Chlorocebus sabaeus (green monkey) : PENK (proenkephalin)
Heterocephalus glaber (naked mole-rat) : Penk (proenkephalin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl856,436,674 - 56,446,671 (-)Ensembl
GRCh38856,440,957 - 56,446,641 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37857,353,513 - 57,359,282 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36857,516,070 - 57,521,143 (-)NCBINCBI36hg18NCBI36
Build 34857,516,069 - 57,521,143NCBI
Celera853,344,310 - 53,350,077 (-)NCBI
Cytogenetic Map8q12.1NCBI
HuRef852,820,608 - 52,826,373 (-)NCBIHuRef
CHM1_1857,405,395 - 57,411,169 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PENK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68998
Created: 2001-11-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.