Penk (proenkephalin) - Rat Genome Database

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Gene: Penk (proenkephalin) Ictidomys tridecemlineatus
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Symbol: Penk
Name: proenkephalin
RGD ID: 12677787
Description: ENCODES a protein that exhibits opioid receptor binding (ortholog); INVOLVED IN aggressive behavior (ortholog); aging (ortholog); behavioral fear response (ortholog); ASSOCIATED WITH alcohol use disorder (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); Anhedonia (ortholog); FOUND IN axon (ortholog); axon terminus (ortholog); cell body fiber (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proenkephalin-A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530371,763,745 - 71,769,230 (+)NCBI
SpeTri2.0NW_0049364963,016,247 - 3,021,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Penk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530371,763,745 - 71,769,230 (+)NCBI
SpeTri2.0NW_0049364963,016,247 - 3,021,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PENK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38856,440,957 - 56,446,641 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl856,436,674 - 56,446,671 (-)EnsemblGRCh38hg38GRCh38
GRCh37857,353,516 - 57,359,200 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36857,516,070 - 57,521,143 (-)NCBINCBI36hg18NCBI36
Build 34857,516,069 - 57,521,143NCBI
Celera853,344,310 - 53,350,077 (-)NCBI
Cytogenetic Map8q12.1NCBI
HuRef852,820,608 - 52,826,373 (-)NCBIHuRef
CHM1_1857,405,395 - 57,411,158 (-)NCBICHM1_1
T2T-CHM13v2.0856,818,203 - 56,823,883 (-)NCBI
Penk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3944,133,536 - 4,138,815 (-)NCBIGRCm39mm39
GRCm39 Ensembl44,133,531 - 4,138,819 (-)Ensembl
GRCm3844,133,536 - 4,138,815 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl44,133,531 - 4,138,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv3744,060,683 - 4,065,592 (-)NCBIGRCm37mm9NCBIm37
MGSCv3644,060,683 - 4,065,592 (-)NCBImm8
Celera44,092,742 - 4,097,651 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map42.31NCBI
Penk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2517,183,799 - 17,189,160 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl517,183,806 - 17,189,129 (-)Ensembl
Rnor_6.0517,056,412 - 17,061,762 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl517,056,419 - 17,061,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0521,834,409 - 21,839,759 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4517,509,323 - 17,514,265 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1517,516,079 - 17,517,452 (-)NCBI
Celera516,529,164 - 16,534,106 (-)NCBICelera
Cytogenetic Map5q12NCBI
Penk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545415,426,017 - 15,426,685 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545415,425,712 - 15,426,685 (-)NCBIChiLan1.0ChiLan1.0
PENK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1850,234,170 - 50,239,949 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl850,234,170 - 50,239,949 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0852,864,388 - 52,870,144 (-)NCBIMhudiblu_PPA_v0panPan3
PENK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1297,757,543 - 7,763,137 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl297,757,857 - 7,762,398 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha298,069,914 - 8,075,462 (-)NCBI
ROS_Cfam_1.0297,832,106 - 7,837,657 (-)NCBI
UMICH_Zoey_3.1297,844,842 - 7,850,120 (-)NCBI
UNSW_CanFamBas_1.0297,975,639 - 7,980,923 (-)NCBI
UU_Cfam_GSD_1.0298,254,882 - 8,260,429 (-)NCBI
PENK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl475,525,555 - 75,530,876 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1475,525,497 - 75,530,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2482,444,889 - 82,449,745 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PENK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1852,458,113 - 52,463,933 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl852,457,904 - 52,463,859 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603989,329,730 - 89,335,563 (+)NCBIVero_WHO_p1.0
Penk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248863,595,450 - 3,613,593 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248863,595,485 - 3,613,117 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005322930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005322930   ⟹   XP_005322987
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530371,763,745 - 71,769,230 (+)NCBI
SpeTri2.0NW_0049364963,016,247 - 3,021,726 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005322987 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3274131 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005322987   ⟸   XM_005322930
- UniProtKB: I3MGR7 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011137 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000009989 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000029885 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011135 UniProtKB/TrEMBL
  ENSSTOT00000039402 UniProtKB/TrEMBL
InterPro Opioid_neupept UniProtKB/TrEMBL
  Proenkphlin_A UniProtKB/TrEMBL
NCBI Gene Penk ENTREZGENE
PANTHER PTHR11438 UniProtKB/TrEMBL
  PTHR11438:SF3 UniProtKB/TrEMBL
Pfam Opiods_neuropep UniProtKB/TrEMBL
PRINTS OPIOIDPRCRSR UniProtKB/TrEMBL
  PENKAPRCRSR UniProtKB/TrEMBL
PROSITE OPIOIDS_PRECURSOR UniProtKB/TrEMBL
UniProt I3MGR7 ENTREZGENE, UniProtKB/TrEMBL