Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | adult respiratory distress syndrome | | ISO | SEPTIN5 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25070658 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | adult respiratory distress syndrome | | ISO | SEPTIN5 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25070658 | |
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# | Reference Title | Reference Citation |
1. | The septin CDCrel-1 binds syntaxin and inhibits exocytosis. | Beites CL, etal., Nat Neurosci 1999 May;2(5):434-9. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
5. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
7. | Sept12 is a component of the mammalian sperm tail annulus. | Steels JD, etal., Cell Motil Cytoskeleton. 2007 Oct;64(10):794-807. |
8. | Reciprocal expression of infant- and adult-preferring transcripts of CDCrel-1 septin gene in the rat neocortex. | Toda S, etal., Biochem Biophys Res Commun 2000 Jul 5;273(2):723-8. |
9. | Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. | Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884. |
PMID:11064363 | PMID:11739749 | PMID:12475938 | PMID:14530399 | PMID:15214843 | PMID:15355307 | PMID:18385322 | PMID:18398426 | PMID:18809578 | PMID:19240081 | PMID:20624595 | PMID:20680483 |
PMID:21767234 | PMID:22589251 | PMID:24722188 | PMID:25416956 | PMID:29476059 | PMID:31814881 |
Septin5 (Rattus norvegicus - Norway rat) |
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SEPTIN5 (Homo sapiens - human) |
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Septin5 (Mus musculus - house mouse) |
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SEPTIN5 (Canis lupus familiaris - dog) |
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SEPTIN5 (Sus scrofa - pig) |
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Variants in Septin5
20 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH133449 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 6 | 72 | 16 | 20 | |||||||||
Low | 3 | 37 | 46 | 30 | 19 | 30 | 8 | 11 | 2 | 19 | 21 | 11 | 8 |
Below cutoff | 11 | 11 | 11 |
RefSeq Acc Id: | ENSRNOT00000041168 ⟹ ENSRNOP00000039995 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000051680 ⟹ ENSRNOP00000042895 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_053931 ⟹ NP_446383 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | NP_446383 ⟸ NM_053931 |
- UniProtKB: | D3ZDH8 (UniProtKB/TrEMBL), A6JSF4 (UniProtKB/TrEMBL), A6JSF3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000039995 ⟸ ENSRNOT00000041168 |
RefSeq Acc Id: | ENSRNOP00000042895 ⟸ ENSRNOT00000051680 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9JJM9-F1-model_v2 | AlphaFold | Q9JJM9 | 1-369 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13698302 | ||||||||
Promoter ID: | EPDNEW_R8823 | ||||||||
Type: | initiation region | ||||||||
Name: | Sept5_1 | ||||||||
Description: | septin 5 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R8824 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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RGD ID: | 13698299 | ||||||||
Promoter ID: | EPDNEW_R8824 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Sept5_2 | ||||||||
Description: | septin 5 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R8823 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621763 | AgrOrtholog |
BioCyc Gene | G2FUF-20667 | BioCyc |
Ensembl Genes | ENSRNOG00000029912 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000041168 | ENTREZGENE |
ENSRNOT00000041168.6 | UniProtKB/TrEMBL | |
ENSRNOT00000051680.7 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.40.50.300 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | G_SEPTIN_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Septin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:116728 | UniProtKB/TrEMBL |
NCBI Gene | 116728 | ENTREZGENE |
PANTHER | PTHR18884:SF68 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SEPTIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Septin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Septin5 | PhenoGen |
PIRSF | Septin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | G_SEPTIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000029912 | RatGTEx |
Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A6JSF3 | ENTREZGENE, UniProtKB/TrEMBL |
A6JSF4 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZDH8 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZT07_RAT | UniProtKB/TrEMBL | |
Q9JJM9 | ENTREZGENE, UniProtKB/Swiss-Prot | |
UniProt Secondary | Q8R2F7 | UniProtKB/Swiss-Prot |
Q9JJM8 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2019-08-05 | Septin5 | septin 5 | Sept5 | septin 5 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-05-02 | Sept5 | septin 5 | Pnutl1 | peanut (Drosophila)-like 1 | Symbol and Name updated to reflect Human and Mouse nomenclature | 1299863 | APPROVED |
2002-08-07 | Pnutl1 | peanut (Drosophila)-like 1 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |