SEPTIN5 (septin 5) - Rat Genome Database

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Gene: SEPTIN5 (septin 5) Sus scrofa
Analyze
Symbol: SEPTIN5
Name: septin 5
RGD ID: 14139964
Description: ENCODES a protein that exhibits GDP binding (ortholog); phosphatidylinositol binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN adult behavior (ortholog); positive regulation of exocytosis (ortholog); regulation of synaptic vesicle docking (ortholog); ASSOCIATED WITH adult respiratory distress syndrome (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN axon terminus (ortholog); calyx of Held (ortholog); cell cortex (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SEPT5; septin-5
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,252,815 - 51,261,244 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,252,815 - 51,260,851 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,892,042 - 54,900,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SEPTIN5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,252,815 - 51,261,244 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,252,815 - 51,260,851 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,892,042 - 54,900,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEPTIN5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,714,503 - 19,723,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,714,503 - 19,724,224 (+)EnsemblGRCh38hg38GRCh38
GRCh372219,702,026 - 19,710,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map22q11.21NCBI
HuRef223,322,278 - 3,330,831 (+)NCBIHuRef
CHM1_12219,701,568 - 19,710,409 (+)NCBICHM1_1
T2T-CHM13v2.02220,091,294 - 20,100,110 (+)NCBIT2T-CHM13v2.0
Septin5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,440,561 - 18,448,688 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,439,252 - 18,448,704 (-)EnsemblGRCm39 Ensembl
GRCm381618,621,811 - 18,629,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,620,502 - 18,629,954 (-)EnsemblGRCm38mm10GRCm38
MGSCv371618,621,904 - 18,630,031 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,535,374 - 18,543,501 (-)NCBIMGSCv36mm8
Celera1619,195,904 - 19,204,004 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.53NCBI
Septin5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,877,946 - 95,883,738 (+)NCBIGRCr8
mRatBN7.21182,373,601 - 82,379,393 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,369,754 - 82,379,393 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,103,250 - 91,109,040 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,764,456 - 83,770,246 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,817,972 - 82,823,762 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,516,377 - 86,522,169 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,512,797 - 86,522,168 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,616,382 - 89,622,161 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,365,193 - 84,370,972 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11184,405,788 - 84,410,228 (+)NCBI
Celera1181,149,418 - 81,155,210 (+)NCBICelera
Cytogenetic Map11q23NCBI
SEPTIN5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,568,776 - 29,573,837 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,569,586 - 29,573,842 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,525,805 - 29,534,528 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,972,530 - 30,980,666 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,971,910 - 30,980,677 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,019,021 - 29,027,743 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,644,701 - 28,653,412 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,730,245 - 29,738,980 (-)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in SEPTIN5
65 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 22 2
Low 9 4 5 2 1 2 3 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000034752   ⟹   ENSSSCP00000028931
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1451,257,149 - 51,261,244 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000037080   ⟹   ENSSSCP00000034317
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1451,252,815 - 51,260,848 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000048800   ⟹   ENSSSCP00000037888
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1451,252,881 - 51,261,244 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000062308   ⟹   ENSSSCP00000039469
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1451,252,815 - 51,260,848 (+)Ensembl
RefSeq Acc Id: XM_001929628   ⟹   XP_001929663
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11451,252,815 - 51,260,851 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003133010   ⟹   XP_003133058
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11451,256,193 - 51,260,851 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001929663   ⟸   XM_001929628
- Peptide Label: isoform X2
- UniProtKB: A0A173G6H0 (UniProtKB/TrEMBL),   A0A287A1T3 (UniProtKB/TrEMBL),   A0A4X1USS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003133058   ⟸   XM_003133010
- Peptide Label: isoform X1
- UniProtKB: A0A480TPT3 (UniProtKB/TrEMBL),   A0A4X1USQ5 (UniProtKB/TrEMBL),   A0A8D0LDV0 (UniProtKB/TrEMBL),   A0A8D0Y398 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000037888   ⟸   ENSSSCT00000048800
RefSeq Acc Id: ENSSSCP00000028931   ⟸   ENSSSCT00000034752
RefSeq Acc Id: ENSSSCP00000034317   ⟸   ENSSSCT00000037080
RefSeq Acc Id: ENSSSCP00000039469   ⟸   ENSSSCT00000062308
Protein Domains
Septin-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010128 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005002706 UniProtKB/TrEMBL
  ENSSSCG00025065359 UniProtKB/TrEMBL
  ENSSSCG00030070397 UniProtKB/TrEMBL
  ENSSSCG00040074452 UniProtKB/TrEMBL
  ENSSSCG00045036272 UniProtKB/TrEMBL
  ENSSSCG00050070402 UniProtKB/TrEMBL
  ENSSSCG00055008451 UniProtKB/TrEMBL
  ENSSSCG00060022875 UniProtKB/TrEMBL
  ENSSSCG00065078388 UniProtKB/TrEMBL
  ENSSSCG00070019123 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000034752 ENTREZGENE
  ENSSSCT00000034752.4 UniProtKB/TrEMBL
  ENSSSCT00000037080.3 UniProtKB/TrEMBL
  ENSSSCT00000048800 ENTREZGENE
  ENSSSCT00000048800.3 UniProtKB/TrEMBL
  ENSSSCT00000062308.3 UniProtKB/TrEMBL
  ENSSSCT00005004282.1 UniProtKB/TrEMBL
  ENSSSCT00005004340.1 UniProtKB/TrEMBL
  ENSSSCT00005004416.1 UniProtKB/TrEMBL
  ENSSSCT00025090136.1 UniProtKB/TrEMBL
  ENSSSCT00030098516.1 UniProtKB/TrEMBL
  ENSSSCT00030098656.1 UniProtKB/TrEMBL
  ENSSSCT00040103019.1 UniProtKB/TrEMBL
  ENSSSCT00045062498.1 UniProtKB/TrEMBL
  ENSSSCT00050095974.1 UniProtKB/TrEMBL
  ENSSSCT00050096001.1 UniProtKB/TrEMBL
  ENSSSCT00055016605.1 UniProtKB/TrEMBL
  ENSSSCT00060031066.1 UniProtKB/TrEMBL
  ENSSSCT00065108624.1 UniProtKB/TrEMBL
  ENSSSCT00070037830.1 UniProtKB/TrEMBL
  ENSSSCT00070037840.1 UniProtKB/TrEMBL
  ENSSSCT00070037862.1 UniProtKB/TrEMBL
  ENSSSCT00070037873.1 UniProtKB/TrEMBL
  ENSSSCT00070037885.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro G_SEPTIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Septin UniProtKB/TrEMBL
KEGG Report ssc:100156312 UniProtKB/TrEMBL
NCBI Gene SEPT5 ENTREZGENE
PANTHER PTHR18884:SF68 UniProtKB/TrEMBL
  SEPTIN UniProtKB/TrEMBL
Pfam Septin UniProtKB/TrEMBL
PIRSF Septin UniProtKB/TrEMBL
PROSITE G_SEPTIN UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A173G6H0 ENTREZGENE, UniProtKB/TrEMBL
  A0A286ZRX1_PIG UniProtKB/TrEMBL
  A0A287A1T3 ENTREZGENE
  A0A287A666_PIG UniProtKB/TrEMBL
  A0A480TPT3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UNM6_PIG UniProtKB/TrEMBL
  A0A4X1USE1_PIG UniProtKB/TrEMBL
  A0A4X1USQ5 ENTREZGENE
  A0A4X1USS9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UTP5_PIG UniProtKB/TrEMBL
  A0A8D0LDV0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Y398 ENTREZGENE, UniProtKB/TrEMBL
  K7GM43_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287A1T3 UniProtKB/TrEMBL
  A0A4X1USQ5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-09 SEPTIN5  septin 5  SEPT5    Symbol and/or name change 5135510 APPROVED