Rab3a (RAB3A, member RAS oncogene family) - Rat Genome Database

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Gene: Rab3a (RAB3A, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab3a
Name: RAB3A, member RAS oncogene family
RGD ID: 3528
Description: Enables several functions, including ATPase binding activity; GTP binding activity; and protein C-terminus binding activity. Involved in regulation of secretion by cell; regulation of synaptic vesicle priming; and synaptic vesicle cycle. Located in several cellular components, including cytosol; secretory vesicle; and terminal bouton. Part of protein-containing complex. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB3A (RAB3A, member RAS oncogene family); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: RAB3; ras-related protein Rab-3A; Ras-related small GTP binding protein 3A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21618,684,185 - 18,688,297 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1618,684,188 - 18,688,336 (-)Ensembl
Rnor_6.01620,435,098 - 20,439,206 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,435,101 - 20,439,206 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,292,166 - 20,296,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,189,765 - 19,193,874 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,189,765 - 19,193,872 (-)NCBI
Celera1618,876,401 - 18,880,512 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Ependymomas  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Brondyk WH, etal., Mol Cell Biol 1995 Mar;15(3):1137-43.
2. Coppola T, etal., Mol Biol Cell 2002 Jun;13(6):1906-15.
3. Cussac D, etal., Mol Cell Endocrinol. 1996 May 31;119(2):195-206.
4. Dai Z, etal., J Cell Biochem. 2017 Nov;118(11):3696-3705. doi: 10.1002/jcb.26016. Epub 2017 May 16.
5. de Hoop MJ, etal., Neuron. 1994 Jul;13(1):11-22.
6. Deak F, etal., EMBO J. 2006 Jun 21;25(12):2856-66. Epub 2006 Jun 8.
7. Francis SC, etal., J Biol Chem 2002 Mar 8;277(10):7816-23.
8. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. GOA data from the GO Consortium
10. Han SY, etal., Biochem J 2000 Nov 15;352 Pt 1:165-73.
11. Handley MT, etal., J Cell Sci. 2007 Mar 15;120(Pt 6):973-84. doi: 10.1242/jcs.03406. Epub 2007 Feb 20.
12. Huang CC, etal., Traffic. 2011 Oct;12(10):1356-70. doi: 10.1111/j.1600-0854.2011.01237.x. Epub 2011 Jul 20.
13. Luo HR, etal., Neuron 2001 Aug 16;31(3):439-51.
14. Maienschein V, etal., Glia. 1999 May;26(3):233-44.
15. Martincic I, etal., J Biol Chem 1997 Oct 24;272(43):26991-8.
16. MGD data from the GO Consortium
17. NCBI rat LocusLink and RefSeq merged data July 26, 2002
18. Ostermeier C and Brunger AT, Cell. 1999 Feb 5;96(3):363-74.
19. Park JB, etal., Biochem J 2002 Mar 15;362(Pt 3):651-7.
20. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
21. RGD automated data pipeline
22. RGD automated import pipeline for gene-chemical interactions
23. Sakisaka T, etal., EMBO J 2002 Nov 15;21(22):6125-35.
24. Stahl B, etal., EMBO J. 1996 Apr 15;15(8):1799-809.
25. Star EN, etal., J Physiol. 2005 Nov 15;569(Pt 1):103-17. Epub 2005 Sep 1.
26. Tabellini G, etal., Eur J Histochem 2001;45(4):347-56.
27. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
28. Tang X, etal., Int J Biol Macromol. 2017 Mar;96:736-742. doi: 10.1016/j.ijbiomac.2016.12.074. Epub 2017 Jan 3.
29. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
30. Wang Z and Thurmond DC, J Cell Sci. 2009 Apr 1;122(Pt 7):893-903.
31. Zahraoui A, etal., Nucleic Acids Res 1988 Feb 11;16(3):1204.
Additional References at PubMed
PMID:2732579   PMID:3317403   PMID:9194562   PMID:10196122   PMID:10748113   PMID:10859313   PMID:11134008   PMID:11182090   PMID:11359932   PMID:11598194   PMID:12167638   PMID:12192047  
PMID:12477932   PMID:12937130   PMID:12972569   PMID:15039103   PMID:15489334   PMID:15837622   PMID:16704978   PMID:16782817   PMID:16822953   PMID:17149709   PMID:17534942   PMID:18448650  
PMID:18798275   PMID:19077034   PMID:20338242   PMID:21128978   PMID:21262767   PMID:21349835   PMID:22248876   PMID:22899725   PMID:24006491   PMID:24472545   PMID:24625528   PMID:24769233  
PMID:24891604   PMID:25002582   PMID:26024738   PMID:27325790   PMID:28634303   PMID:29476059  


Genomics

Comparative Map Data
Rab3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21618,684,185 - 18,688,297 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1618,684,188 - 18,688,336 (-)Ensembl
Rnor_6.01620,435,098 - 20,439,206 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,435,101 - 20,439,206 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,292,166 - 20,296,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,189,765 - 19,193,874 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,189,765 - 19,193,872 (-)NCBI
Celera1618,876,401 - 18,880,512 (-)NCBICelera
Cytogenetic Map16p14NCBI
RAB3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,196,784 - 18,204,042 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1918,196,784 - 18,204,042 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,307,594 - 18,314,852 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,168,611 - 18,175,839 (-)NCBINCBI36hg18NCBI36
Build 341918,168,610 - 18,175,839NCBI
Celera1918,209,348 - 18,216,613 (-)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1917,871,059 - 17,878,307 (-)NCBIHuRef
CHM1_11918,307,151 - 18,314,427 (-)NCBICHM1_1
T2T-CHM13v2.01918,330,909 - 18,338,143 (-)NCBI
Rab3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,207,258 - 71,211,276 (+)NCBIGRCm39mm39
GRCm39 Ensembl871,207,328 - 71,211,323 (+)Ensembl
GRCm38870,754,703 - 70,758,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,754,679 - 70,758,677 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,278,578 - 73,282,585 (+)NCBIGRCm37mm9NCBIm37
MGSCv36873,683,712 - 73,687,666 (+)NCBImm8
Celera873,315,980 - 73,319,984 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Rab3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,221,366 - 3,224,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,220,108 - 3,224,376 (+)NCBIChiLan1.0ChiLan1.0
RAB3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11918,649,166 - 18,656,768 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,649,166 - 18,656,768 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01917,672,661 - 17,679,541 (-)NCBIMhudiblu_PPA_v0panPan3
RAB3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,796,740 - 44,802,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,796,895 - 44,801,692 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,710,693 - 44,716,183 (+)NCBI
ROS_Cfam_1.02045,282,514 - 45,288,006 (+)NCBI
ROS_Cfam_1.0 Ensembl2045,282,528 - 45,287,983 (+)Ensembl
UMICH_Zoey_3.12044,519,685 - 44,525,177 (+)NCBI
UNSW_CanFamBas_1.02044,930,125 - 44,935,626 (+)NCBI
UU_Cfam_GSD_1.02045,205,632 - 45,211,124 (+)NCBI
Rab3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,441,225 - 203,447,398 (+)NCBI
SpeTri2.0NW_0049365962,990,367 - 2,995,935 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,603,117 - 59,609,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,603,090 - 59,609,773 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,142,410 - 59,149,077 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,671,388 - 16,678,780 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660742,699,847 - 2,707,085 (+)NCBIVero_WHO_p1.0
Rab3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,530,312 - 1,536,129 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249081,532,857 - 1,537,159 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH130738  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,683,921 - 18,684,127 (+)MAPPERmRatBN7.2
Rnor_6.01620,434,835 - 20,435,040NCBIRnor6.0
Rnor_5.01620,291,903 - 20,292,108UniSTSRnor5.0
RGSC_v3.41619,189,502 - 19,189,707UniSTSRGSC3.4
Celera1618,876,138 - 18,876,343UniSTS
RH 3.4 Map16195.1UniSTS
Cytogenetic Map16p14UniSTS
RH133798  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,684,256 - 18,684,416 (+)MAPPERmRatBN7.2
Rnor_6.01620,435,170 - 20,435,329NCBIRnor6.0
Rnor_5.01620,292,238 - 20,292,397UniSTSRnor5.0
RGSC_v3.41619,189,837 - 19,189,996UniSTSRGSC3.4
Celera1618,876,473 - 18,876,632UniSTS
RH 3.4 Map16196.0UniSTS
Cytogenetic Map16p14UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8hepatic copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:58
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000026391
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 35 2 2 72 25 25 5
Low 3 8 55 41 19 41 8 9 2 10 16 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000026391   ⟹   ENSRNOP00000026392
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,684,188 - 18,688,336 (-)Ensembl
Rnor_6.0 Ensembl1620,435,101 - 20,439,206 (-)Ensembl
RefSeq Acc Id: NM_013018   ⟹   NP_037150
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21618,684,185 - 18,688,297 (-)NCBI
Rnor_6.01620,435,098 - 20,439,206 (-)NCBI
Rnor_5.01620,292,166 - 20,296,274 (-)NCBI
RGSC_v3.41619,189,765 - 19,193,874 (-)RGD
Celera1618,876,401 - 18,880,512 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_037150 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87580 (Get FASTA)   NCBI Sequence Viewer  
  CAA30005 (Get FASTA)   NCBI Sequence Viewer  
  EDL90732 (Get FASTA)   NCBI Sequence Viewer  
  P63012 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037150   ⟸   NM_013018
- UniProtKB: P63012 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000026392   ⟸   ENSRNOT00000026391

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63012-F1-model_v2 AlphaFold P63012 1-220 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700018
Promoter ID:EPDNEW_R10540
Type:multiple initiation site
Name:Rab3a_1
Description:RAB3A, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,439,233 - 20,439,293EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3528 AgrOrtholog
BIND 134440
  134445
BioCyc Gene G2FUF-11805 BioCyc
Ensembl Genes ENSRNOG00000019433 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000026392 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026391 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7314616 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Rab3 UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
KEGG Report rno:25531 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105485 IMAGE-MGC_LOAD
NCBI Gene 25531 ENTREZGENE
Pfam Ras UniProtKB/Swiss-Prot
PhenoGen Rab3a PhenoGen
PROSITE RAB UniProtKB/Swiss-Prot
SMART RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
TIGR TC214203
TIGRFAMs small_GTP UniProtKB/Swiss-Prot
UniProt P63012 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P05713 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Rab3a  RAB3A, member RAS oncogene family    Ras-related small GTP binding protein 3A  Name updated 629478 APPROVED
2002-06-10 Rab3a  Ras-related small GTP binding protein 3A      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference