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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RAB3A mRNA] | CTD | PMID:31150632 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | RGD:11212 | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:15099020 | 17beta-estradiol | multiple interactions | ISO | RGD:735498 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of RAB3A mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:11212 | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAB3A mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RAB3A mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:11212 | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of RAB3A mRNA | CTD | PMID:25975270 | aflatoxin B1 | increases methylation | ISO | RGD:735498 | 6480464 | Aflatoxin B1 results in increased methylation of RAB3A polyA tail | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RAB3A mRNA | CTD | PMID:16483693 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of RAB3A mRNA | CTD | PMID:30779732 | aripiprazole | increases expression | EXP | | 6480464 | Aripiprazole results in increased expression of RAB3A mRNA | CTD | PMID:17868501 | atrazine | increases expression | ISO | RGD:735498 | 6480464 | Atrazine results in increased expression of RAB3A mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases methylation | ISO | RGD:735498 | 6480464 | Benzo(a)pyrene results in decreased methylation of RAB3A 5' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RAB3A mRNA | CTD | PMID:25181051 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of RAB3A mRNA | CTD | PMID:19167457 | carbon nanotube | decreases expression | ISO | RGD:11212 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | multiple interactions | ISO | RGD:735498 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of RAB3A mRNA | CTD | PMID:27392435 | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of RAB3A mRNA | CTD | PMID:16076954 | copper(II) sulfate | increases expression | ISO | RGD:735498 | 6480464 | Copper Sulfate results in increased expression of RAB3A mRNA | CTD | PMID:19549813 | dicrotophos | increases expression | ISO | RGD:735498 | 6480464 | dicrotophos results in increased expression of RAB3A mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | RGD:735498 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB3A mRNA | CTD | PMID:27188386 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of RAB3A mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | RGD:735498 | 6480464 | entinostat results in increased expression of RAB3A mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | RGD:735498 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB3A mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | RGD:11212 | 6480464 | Ethanol results in increased expression of RAB3A mRNA | CTD | PMID:30319688 | ferroheme b | decreases expression | ISO | RGD:11212 | 6480464 | Heme metabolite results in decreased expression of RAB3A mRNA | CTD | PMID:19191707 | furan | decreases expression | ISO | RGD:11212 | 6480464 | furan results in decreased expression of RAB3A mRNA | CTD | PMID:24183702 | gamma-tocopherol | increases expression | ISO | RGD:11212 | 6480464 | Tocopherols results in increased expression of RAB3A mRNA | CTD | PMID:17654050 | GDP | affects binding | EXP | | 6480464 | Guanosine Diphosphate binds to RAB3A protein | CTD | PMID:7929154 | GDP | multiple interactions | EXP | | 6480464 | [alpha-latrotoxin promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein], [black widow spider venom promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein] | CTD | PMID:7929154 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RAB3A mRNA | CTD | PMID:33387578 | GTP | affects binding | EXP | | 6480464 | [RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein more ... | CTD | PMID:29289693, PMID:7929154 | GTP | increases cleavage | EXP | | 6480464 | RAB3A protein results in increased cleavage of Guanosine Triphosphate | CTD | PMID:7929154 | GTP | multiple interactions | EXP | | 6480464 | [alpha-latrotoxin promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein] more ... | CTD | PMID:29289693, PMID:7929154 | heme b | decreases expression | ISO | RGD:11212 | 6480464 | Heme metabolite results in decreased expression of RAB3A mRNA | CTD | PMID:19191707 | hydralazine | multiple interactions | ISO | RGD:735498 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RAB3A mRNA | CTD | PMID:17183730 | ivermectin | decreases expression | ISO | RGD:735498 | 6480464 | Ivermectin results in decreased expression of RAB3A protein | CTD | PMID:32959892 | lithocholic acid | affects binding | EXP | | 6480464 | Lithocholic Acid binds to RAB3A protein | CTD | PMID:18641422 | manganese(II) chloride | multiple interactions | EXP | | 6480464 | manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein] more ... | CTD | PMID:29289693 | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of RAB3A mRNA | CTD | PMID:28801915 | morphine | affects expression | ISO | RGD:11212 | 6480464 | Morphine affects the expression of RAB3A protein | CTD | PMID:16522322 | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | RGD:11212 | 6480464 | Ethylnitrosourea results in increased mutagenesis of RAB3A gene | CTD | PMID:16724327 | N-methyl-D-aspartic acid | multiple interactions | ISO | RGD:11212 | 6480464 | N-Methylaspartate inhibits the reaction [gelsenicine results in increased phosphorylation of RAB3A protein] | CTD | PMID:34389372 | ozone | decreases expression | EXP | | 6480464 | Ozone results in decreased expression of RAB3A mRNA | CTD | PMID:16330353 | paracetamol | increases expression | ISO | RGD:735498 | 6480464 | Acetaminophen results in increased expression of RAB3A mRNA | CTD | PMID:21420995 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RAB3A mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | RGD:735498 | 6480464 | Acetaminophen results in decreased expression of RAB3A mRNA | CTD | PMID:22230336 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of RAB3A mRNA | CTD | PMID:32680482 | pirinixic acid | decreases expression | ISO | RGD:11212 | 6480464 | pirinixic acid results in decreased expression of RAB3A mRNA | CTD | PMID:23811191 | propanal | increases expression | ISO | RGD:735498 | 6480464 | propionaldehyde results in increased expression of RAB3A mRNA | CTD | PMID:26079696 | rotenone | multiple interactions | ISO | RGD:11212 | 6480464 | Rotenone promotes the reaction [SNCA protein mutant form binds to RAB3A protein] | CTD | PMID:15099020 | SB 431542 | multiple interactions | ISO | RGD:735498 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB3A mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | RGD:735498 | 6480464 | sodium arsenite results in increased expression of RAB3A mRNA | CTD | PMID:12016162, PMID:34032870 | sodium fluoride | increases expression | ISO | RGD:11212 | 6480464 | Sodium Fluoride results in increased expression of RAB3A protein | CTD | PMID:27548804 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RAB3A mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of RAB3A mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of RAB3A mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of RAB3A mRNA | CTD | PMID:30012374 | tocopherol | increases expression | ISO | RGD:11212 | 6480464 | Tocopherols results in increased expression of RAB3A mRNA | CTD | PMID:17654050 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of RAB3A mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of RAB3A mRNA | CTD | PMID:23558232 | triptonide | decreases expression | ISO | RGD:11212 | 6480464 | triptonide results in decreased expression of RAB3A mRNA | CTD | PMID:33045310 | valproic acid | multiple interactions | ISO | RGD:735498 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RAB3A mRNA | CTD | PMID:17183730 | valproic acid | increases expression | ISO | RGD:735498 | 6480464 | Valproic Acid results in increased expression of RAB3A mRNA | CTD | PMID:28001369 | valproic acid | affects expression | ISO | RGD:735498 | 6480464 | Valproic Acid affects the expression of RAB3A mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of RAB3A mRNA | CTD | PMID:23869203 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of RAB3A mRNA | CTD | PMID:23034163 | zinc atom | multiple interactions | EXP | | 6480464 | [MT3 protein binds to RAB3A protein] which results in decreased susceptibility to Zinc | CTD | PMID:15039103 | zinc atom | increases expression | ISO | RGD:735498 | 6480464 | Zinc deficiency results in increased expression of RAB3A mRNA | CTD | PMID:18356318 | zinc(0) | multiple interactions | EXP | | 6480464 | [MT3 protein binds to RAB3A protein] which results in decreased susceptibility to Zinc | CTD | PMID:15039103 | zinc(0) | increases expression | ISO | RGD:735498 | 6480464 | Zinc deficiency results in increased expression of RAB3A mRNA | CTD | PMID:18356318 | |