 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Brondyk WH, etal., Mol Cell Biol 1995 Mar;15(3):1137-43. |
| 2. | Coppola T, etal., Mol Biol Cell 2002 Jun;13(6):1906-15. |
| 3. | Cussac D, etal., Mol Cell Endocrinol. 1996 May 31;119(2):195-206. |
| 4. | Dai Z, etal., J Cell Biochem. 2017 Nov;118(11):3696-3705. doi: 10.1002/jcb.26016. Epub 2017 May 16. |
| 5. | de Hoop MJ, etal., Neuron. 1994 Jul;13(1):11-22. |
| 6. | Deak F, etal., EMBO J. 2006 Jun 21;25(12):2856-66. Epub 2006 Jun 8. |
| 7. | Francis SC, etal., J Biol Chem 2002 Mar 8;277(10):7816-23. |
| 8. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 9. | GOA data from the GO Consortium |
| 10. | Han SY, etal., Biochem J 2000 Nov 15;352 Pt 1:165-73. |
| 11. | Handley MT, etal., J Cell Sci. 2007 Mar 15;120(Pt 6):973-84. doi: 10.1242/jcs.03406. Epub 2007 Feb 20. |
| 12. | Huang CC, etal., Traffic. 2011 Oct;12(10):1356-70. doi: 10.1111/j.1600-0854.2011.01237.x. Epub 2011 Jul 20. |
| 13. | Luo HR, etal., Neuron 2001 Aug 16;31(3):439-51. |
| 14. | Maienschein V, etal., Glia. 1999 May;26(3):233-44. |
| 15. | Martincic I, etal., J Biol Chem 1997 Oct 24;272(43):26991-8. |
| 16. | MGD data from the GO Consortium |
| 17. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 18. | Ostermeier C and Brunger AT, Cell. 1999 Feb 5;96(3):363-74. |
| 19. | Park JB, etal., Biochem J 2002 Mar 15;362(Pt 3):651-7. |
| 20. | Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010. |
| 21. | RGD automated data pipeline |
| 22. | RGD automated import pipeline for gene-chemical interactions |
| 23. | Sakisaka T, etal., EMBO J 2002 Nov 15;21(22):6125-35. |
| 24. | Stahl B, etal., EMBO J. 1996 Apr 15;15(8):1799-809. |
| 25. | Star EN, etal., J Physiol. 2005 Nov 15;569(Pt 1):103-17. Epub 2005 Sep 1. |
| 26. | Tabellini G, etal., Eur J Histochem 2001;45(4):347-56. |
| 27. | Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46. |
| 28. | Tang X, etal., Int J Biol Macromol. 2017 Mar;96:736-742. doi: 10.1016/j.ijbiomac.2016.12.074. Epub 2017 Jan 3. |
| 29. | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
| 30. | Wang Z and Thurmond DC, J Cell Sci. 2009 Apr 1;122(Pt 7):893-903. |
| 31. | Zahraoui A, etal., Nucleic Acids Res 1988 Feb 11;16(3):1204. |
References - uncurated| PubMed | 2732579 3317403 9194562 10196122 10748113 10859313 11134008 11182090 11359932 11598194 12167638 12192047 12477932 12937130 12972569 15039103 15489334 15837622 16704978 16782817 16822953 17149709 17534942 18448650 18798275 19077034 20338242 21128978 21262767 21349835 22248876 22899725 24006491 24472545 24625528 24769233 24891604 25002582 26024738 27325790 28634303 29476059 |
Genomics
Comparative Map Data| Rab3a (Rattus norvegicus - Norway rat) |
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| RAB3A (Homo sapiens - human) |
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| Rab3a (Mus musculus - house mouse) |
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| Rab3a (Chinchilla lanigera - long-tailed chinchilla) |
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| RAB3A (Pan paniscus - bonobo/pygmy chimpanzee) |
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| RAB3A (Canis lupus familiaris - dog) |
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| Rab3a (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| RAB3A (Sus scrofa - pig) |
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| RAB3A (Chlorocebus sabaeus - African green monkey) |
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| Rab3a (Heterocephalus glaber - naked mole-rat) |
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Position Markers| RH130738 |
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| RH133798 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 35 | 2 | 2 | 72 | 25 | 25 | 5 | ||||||
| Low | 3 | 8 | 55 | 41 | 19 | 41 | 8 | 9 | 2 | 10 | 16 | 6 | 8 |
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_013018 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07024876 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01086846 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC087580 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474031 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ214110 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ214415 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ214465 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| X06889 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000026391 ⟹ ENSRNOP00000026392 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_013018 ⟹ NP_037150 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GAGCCTCCACCGCCGCCTGCAGCCCCCGCATCTTCTTCTGGGGCCCGGTCGCCAGCGCAGTCGChide sequence |
Protein Sequences| Protein RefSeqs | NP_037150 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAH87580 | (Get FASTA) | NCBI Sequence Viewer |
| CAA30005 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL90732 | (Get FASTA) | NCBI Sequence Viewer | |
| P63012 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_037150 ⟸ NM_013018 |
| - UniProtKB: | P63012 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIhide sequence |
| RefSeq Acc Id: | ENSRNOP00000026392 ⟸ ENSRNOT00000026391 |
TranscriptomePromoters| RGD ID: | 13700018 | ||||||||
| Promoter ID: | EPDNEW_R10540 | ||||||||
| Type: | multiple initiation site | ||||||||
| Name: | Rab3a_1 | ||||||||
| Description: | RAB3A, member RAS oncogene family | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:3528 | AgrOrtholog |
| BIND | 134440 | |
| 134445 | ||
| Ensembl Genes | ENSRNOG00000019433 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000026392 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000026391 | ENTREZGENE, UniProtKB/Swiss-Prot |
| IMAGE_CLONE | IMAGE:7314616 | IMAGE-MGC_LOAD |
| InterPro | P-loop_NTPase | UniProtKB/Swiss-Prot |
| Rab3 | UniProtKB/Swiss-Prot | |
| Small_GTP-bd_dom | UniProtKB/Swiss-Prot | |
| Small_GTPase | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:25531 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:105485 | IMAGE-MGC_LOAD |
| NCBI Gene | 25531 | ENTREZGENE |
| Pfam | Ras | UniProtKB/Swiss-Prot |
| PhenoGen | Rab3a | PhenoGen |
| PROSITE | RAB | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot |
| TIGR | TC214203 | |
| TIGRFAMs | small_GTP | UniProtKB/Swiss-Prot |
| UniGene | Rn.44409 | ENTREZGENE |
| UniProt | P63012 | ENTREZGENE, UniProtKB/Swiss-Prot |
| UniProt Secondary | P05713 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2003-04-09 | Rab3a | RAB3A, member RAS oncogene family | Ras-related small GTP binding protein 3A | Name updated | 629478 | APPROVED | |
| 2002-06-10 | Rab3a | Ras-related small GTP binding protein 3A | Symbol and Name status set to approved | 70586 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
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| More on Rab3a | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 3528 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-07-07 |
| Status: | ACTIVE |
